Macrophage migration technique using coccidioidin.

abstract：:Streptococcus suis capsular type 2 is an important etiological agent of swine meningitis, and it is also a zoonotic agent. Since one hypothesis of the pathogenesis of S. suis infection is that bacteria enter the bloodstream and invade the meninges and other tissues in close association with mononuclear phagocytes, the...

journal_title：Infection and immunity

authors： Segura M,Gottschalk M

更新日期：2002-08-01 00:00:00

abstract：:The 34-kilodalton (kDa) antigen of Treponema pallidum subsp. pallidum (T. pallidum) is a pathogen-specific integral membrane protein. DNA sequence analysis of the cloned gene revealed an open reading frame encoding a primary product of 204 residues with a molecular mass of 22,087 daltons. Sequences that correspond to ...

journal_title：Infection and immunity

authors： Swancutt MA,Riley BS,Radolf JD,Norgard MV

更新日期：1989-11-01 00:00:00

abstract：:We have developed a rapid, continuous method for real-time monitoring of biofilms, both in vitro and in a mouse infection model, through noninvasive imaging of bioluminescent bacteria colonized on Teflon catheters. Two important biofilm-forming bacterial pathogens, Staphylococcus aureus and Pseudomonas aeruginosa, wer...

journal_title：Infection and immunity

authors： Kadurugamuwa JL,Sin L,Albert E,Yu J,Francis K,DeBoer M,Rubin M,Bellinger-Kawahara C,Parr TR Jr,Contag PR

更新日期：2003-02-01 00:00:00

abstract：:Lysogenic conversion of Shigella flexneri type antigens was studied with the aid of wild-type and thermosensitive mutant phages. With all wild-type phages, the appearance of glycosylated antigen was accompanied by the appearance of polyprenyl phosphate glucose synthetase activity. With some of the mutant phages, the a...

journal_title：Infection and immunity

authors： Financsek I,Ketyi I,Sasak W,Jankowski W,Janczura E,Chojnacki T

更新日期：1976-12-01 00:00:00

abstract：:A receptor specific for lipoglycans from Acholeplasma axanthum and Acholeplasma granularum was isolated from sheep erythrocyte stroma by extraction with n-pentanol and permeation chromatography. The purified receptor appeared as one band on sodium dodecyl sulfate-polyacrylamide gels and stained with Coomassie blue, pe...

journal_title：Infection and immunity

authors： Al-Samarrai TH,Smith PF,Lynn RJ

更新日期：1982-12-01 00:00:00

abstract：:The recent development of acellular pertussis vaccines has been a significant improvement in the conventional whole-cell diphtheria-pertussis-tetanus toxoid vaccines, but high production costs will limit its widespread use in developing countries. Since Mycobacterium bovis BCG vaccination against tuberculosis is used ...

journal_title：Infection and immunity

authors： Nascimento IP,Dias WO,Mazzantini RP,Miyaji EN,Gamberini M,Quintilio W,Gebara VC,Cardoso DF,Ho PL,Raw I,Winter N,Gicquel B,Rappuoli R,Leite LC

更新日期：2000-09-01 00:00:00

abstract：:The hemolysins of Serpulina hyodysenteriae are active at 27 to 40 degrees C and pH 3 to 9 and are unaffected by enzymatic inhibitors. Pore formation was demonstrated by the inhibition of hemolysis with molecules of 2.0 to 2.3 nm in diameter and the release of 86rubidium from erythrocytes without hemoglobin release aft...

journal_title：Infection and immunity

authors： Hyatt DR,Joens LA

更新日期：1997-11-01 00:00:00

abstract：:Studies concerned with the mechanisms responsible for relative resistance or susceptibility of strains of inbred mice to Trypanosoma musculi infections are presented. Treatment with 400 rads of ionizing radiation, silica dust, or trypan blue (reticuloendothelial blocking agents) rendered C3H mice unable to control the...

journal_title：Infection and immunity

authors： Albright JW,Albright JF

更新日期：1989-06-01 00:00:00

abstract：:Mycobacterium tuberculosis grows within the phagocytic vacuoles of macrophages, where it encounters a moderately acidic and possibly nutrient-restricted environment. Other mycobacterial species encounter acidic conditions in soil and aquatic environments. We have evaluated the influence of pH and divalent cation level...

journal_title：Infection and immunity

authors： Piddington DL,Kashkouli A,Buchmeier NA

更新日期：2000-08-01 00:00:00

abstract：:Uropathogenic Escherichia coli (UPEC) is responsible for the majority of uncomplicated urinary tract infections (UTI) and represents the most common bacterial infection in adults. UPEC utilizes a wide range of virulence factors to colonize the host, including the novel repeat-in-toxin (RTX) protein TosA, which is spec...

journal_title：Infection and immunity

authors： Vigil PD,Wiles TJ,Engstrom MD,Prasov L,Mulvey MA,Mobley HL

更新日期：2012-02-01 00:00:00

abstract：:Escherichia coli strains that cause nonbloody diarrhea in infants are known to present three distinct patterns of adherence to epithelial cells, namely, localized (LA), diffuse (DA), and aggregative (AA) adherence. Strains with LA (typical Enteropathogenic Escherichia coli [EPEC]) are well recognized as a cause of sec...

journal_title：Infection and immunity

authors： Scaletsky IC,Pedroso MZ,Oliva CA,Carvalho RL,Morais MB,Fagundes-Neto U

更新日期：1999-07-01 00:00:00

abstract：:Neisseria meningitidis is a human-specific pathogen and leading cause of meningitis and septicemia. Factor H binding protein (fHbp), a virulence factor which protects N. meningitidis from innate immunity by binding the human complement regulator factor H (fH) with high affinity, is also a key antigen in vaccines being...

journal_title：Infection and immunity

authors： van der Veen S,Johnson S,Jongerius I,Malik T,Genovese A,Santini L,Staunton D,Ufret-Vincenty RL,Pickering MC,Lea SM,Tang CM

更新日期：2014-03-01 00:00:00

abstract：:The morphology and pathology of cultured mouse glomeruli were examined at the cellular and subcellular levels after infection with a physiological isotonic L-form of Streptococcus pyogenes type 12 or exposure to streptococcal lipoteichoic acid. These changes, as viewed by light microscopy, were identical regardless of...

journal_title：Infection and immunity

authors： Tomlinson K,Leon O,Panos C

更新日期：1983-12-01 00:00:00

abstract：:Cell-mediated immunity is pivotal in host resistance to Blastomyces dermatitidis infection. Immunization of mice with the WI-1 adhesin enhances resistance against experimental pulmonary infection but elicits features of a mixed T-helper-cell immune response. Immune mice acquire delayed-type hypersensitivity (DTH) but ...

journal_title：Infection and immunity

authors： Wüthrich M,Finkel-Jiminez BE,Klein BS

更新日期：2000-12-01 00:00:00

abstract：:Peritoneal exudate T lymphocytes from Listeria monocytogenes-immune mice in the presence of the homologous antigen (heat-killed L. monocytogenes) and normal macrophages showed L. monocytogenes-specific proliferative responses. Proliferation was inhibited by macrophages from L. monocytogenes- or Corynebacterium parvum-...

journal_title：Infection and immunity

authors： Kaufmann SH,Simon MM,Hahn H

更新日期：1982-12-01 00:00:00

abstract：:Humoral and cellular immune responses to several antigens were compared in control and hypercholesterolemic groups of monkeys. Chronic hypercholesterolemia, with concomitant hyperphospholipidemia and hypotriglyceridemia, was produced experimentally by feeding monkeys a high-fat, high-cholesterol diet. When studied pri...

journal_title：Infection and immunity

authors： Fiser RH Jr,Denniston JC,McGann VG,Kaplan J,Alder WH 3rd,Kastello MD,Beisel WR

更新日期：1973-07-01 00:00:00

abstract：:Growing Streptococcus gordonii Spp+ phase variants, which have normal levels of glucosyltransferase (GTF) activity, use sucrose to promote their accumulation on surfaces by forming a cohesive bacterium-insoluble glucan polymer mass (BPM). Spp- phase variants, which have lower levels of GTF activity, do not form BPMs a...

journal_title：Infection and immunity

authors： Vickerman MM,Jones GW

更新日期：1992-10-01 00:00:00

abstract：:Some strains of Streptococcus mutans were found to recognize and bind collagen type I. Binding of 125I-labeled collagen type I was specific in that collagen types I and II, but not unrelated proteins, were able to inhibit binding of the labeled ligand to bacteria. Collagen binding to S. mutans was partially reversible...

journal_title：Infection and immunity

authors： Switalski LM,Butcher WG,Caufield PC,Lantz MS

更新日期：1993-10-01 00:00:00

abstract：:Pseudomonas aeruginosa utilizes a number of distinct pathways to secrete proteins that play various roles during infection. These include the type II secretion system, which is responsible for the secretion of the majority of exoproducts into the surrounding environment, including toxins and degradative enzymes. In co...

journal_title：Infection and immunity

authors： Lee VT,Smith RS,Tümmler B,Lory S

更新日期：2005-03-01 00:00:00

abstract：:When phagocytosis of Staphylococcus aureus by human polymorphonuclear leukocytes (PMN) takes place on the surface of cultured human endothelial cells, the endothelial monolayers are damaged by lysosomal enzymes that are released by the PMN. Because PMN can phagocytose opsonized as well as unopsonized staphylococci on ...

journal_title：Infection and immunity

authors： Vandenbroucke-Grauls CM,Thijssen HM,Verhoef J

更新日期：1987-06-01 00:00:00

abstract：:Gamma interferon (IFN-gamma) is produced in response to circulating lipopolysaccharide (LPS) and contributes to the lethality of endotoxic shock. To address the cellular source of IFN-gamma production in vivo, T cells and B cells were magnetically purified from C57BL/6 mouse spleens 5 h following endotoxin injection. ...

journal_title：Infection and immunity

authors： Heinzel FP,Rerko RM,Ling P,Hakimi J,Schoenhaut DS

更新日期：1994-10-01 00:00:00

abstract：:The genes encoding alpha-hemolysin and mannose-resistant hemagglutination were shown to be closely linked in cloned DNA from two Escherichia coli urinary tract isolates of serotypes O4 (J96) and O6 (C1212). DNA hybridization experiments demonstrated that the hly and mrh gene clusters of other E. coli O6 serotypes were...

journal_title：Infection and immunity

authors： Low D,David V,Lark D,Schoolnik G,Falkow S

更新日期：1984-01-01 00:00:00

abstract：:Intact tissues are relatively resistant to Pseudomonas aeruginosa-induced disease, and injury predisposes tissue to infection. Intact epithelia contain polarized cells that have distinct apical and basolateral membranes with unique lipids and proteins. In this study, the role of cell polarity in epithelial cell suscep...

journal_title：Infection and immunity

authors： Fleiszig SM,Evans DJ,Do N,Vallas V,Shin S,Mostov KE

更新日期：1997-07-01 00:00:00

abstract：:The mechanism(s) of interaction between Mycoplasma pulmonis and eucaryotic cells was studied by adherence to and hemagglutination of erythrocytes. Simple and complex carbohydrates and glycoproteins were unable to inhibit either adherence or hemagglutination, indicating that neither was a lectin activity. Both interact...

journal_title：Infection and immunity

authors： Minion FC,Cassell GH,Pnini S,Kahane I

更新日期：1984-05-01 00:00:00

abstract：:Monoclonal antibodies secreted by six hybridomas and recognizing antigenic sites on glycoproteins gC, gAB, gD, gE, and gF of herpes simplex virus type 2 were examined for their ability to protect BALB/c mice from lethal infection by the virus. Administration of monoclonal antibodies to individual glycoproteins intrape...

journal_title：Infection and immunity

authors： Balachandran N,Bacchetti S,Rawls WE

更新日期：1982-09-01 00:00:00

abstract：:Pathogenic members of the Yersinia genus require the translocator protein LcrV for proper function of the type III secretion apparatus, which is crucial for virulence. LcrV has also been reported to play an independent immunosuppressive role via the induction of interleukin-10 (IL-10) through stimulation of Toll-like ...

journal_title：Infection and immunity

authors： Pouliot K,Pan N,Wang S,Lu S,Lien E,Goguen JD

更新日期：2007-07-01 00:00:00

abstract：:Rhodococcus equi is an intracellular pathogen which causes pneumonia in young horses and in immunocompromised humans. R. equi arrests phagosome maturation in macrophages at a prephagolysosome stage and grows inside a privileged compartment. Here, we show that, in murine macrophages activated with gamma interferon and ...

journal_title：Infection and immunity

authors： von Bargen K,Wohlmann J,Taylor GA,Utermöhlen O,Haas A

更新日期：2011-05-01 00:00:00

abstract：:We purified three proline-rich antimicrobial peptides from elastase-treated extracts of sheep and goat leukocytes and subjected two of them, OaBac5alpha and ChBac5, to detailed analysis. OaBac5alpha and ChBac5 were homologous to each other and to bovine Bac5. Both exhibited potent, broad-spectrum antimicrobial activit...

journal_title：Infection and immunity

authors： Shamova O,Brogden KA,Zhao C,Nguyen T,Kokryakov VN,Lehrer RI

更新日期：1999-08-01 00:00:00

abstract：:Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single infectious agent. Recent studies targeting candidate genes and "case-control" association have revealed numerous polymorphisms implicated in host susceptibility to TB. Here, we review current progress in the understanding of cau...

journal_title：Infection and immunity

authors： Azad AK,Sadee W,Schlesinger LS

更新日期：2012-10-01 00:00:00

abstract：:Raising the magnesium level from 0.4 to 1.5 mM in a medium containing only amino acids (2.08%), salts, and vitamins increased enterotoxin B production by Staphylococcus aureus S-6 by about 80%. The level of phosphates in the medium was lowered to one-tenth (to 2.87 mM) the original amount without adversely affecting g...

journal_title：Infection and immunity

authors： Keller GM,Hanson RS,Bergdoll MS

更新日期：1978-04-01 00:00:00