Collagen mediates adhesion of Streptococcus mutans to human dentin.

abstract：:The effect of growth temperature on the virulence of a strain of broth-grown serogroup 1 Legionella pneumophila (Wadsworth F889) was examined by growing the bacterium at different temperatures and then infecting guinea pigs (by intratracheal injection) and guinea pig alveolar macrophages. The 50% lethal dose for guine...

journal_title：Infection and immunity

authors： Edelstein PH,Beer KB,DeBoynton ED

更新日期：1987-11-01 00:00:00

abstract：:Mycobacterium leprae are killed by myeloperoxidase (or eosinophil peroxidase), H2O2, and a halide, thus suggesting a mechanism for their destruction by peroxidase-containing phagocytes. ...

journal_title：Infection and immunity

authors： Klebanoff SJ,Shepard CC

更新日期：1984-05-01 00:00:00

abstract：:In the present study, the role of virulence factors in and the effect of opsonization on the interactions between Bordetella pertussis and human monocytes were investigated. The methods used facilitated the distinction between attachment and ingestion of bacteria by monocytes. Nonopsonized virulent B. pertussis cells ...

journal_title：Infection and immunity

authors： Hazenbos WL,van den Berg BM,van't Wout JW,Mooi FR,van Furth R

更新日期：1994-11-01 00:00:00

abstract：:Streptococcus pneumoniae is a leading cause of bacterial pneumonia, meningitis, and sepsis in children. Human immunity to pneumococcal infections has been assumed to depend on anticapsular antibodies. However, recent findings from murine models suggest that alternative mechanisms, dependent on T helper cells, are also...

journal_title：Infection and immunity

authors： Olliver M,Hiew J,Mellroth P,Henriques-Normark B,Bergman P

更新日期：2011-10-01 00:00:00

abstract：:Genomics revealed the sequence of 3924 genes of the H37Rv strain of Mycobacterium tuberculosis. Proteomics complements genomics in showing which genes are really expressed, and here we show the expression of six genes not predicted by genomics, as proved by two-dimensional electrophoresis and matrix-assisted laser des...

journal_title：Infection and immunity

authors： Jungblut PR,Müller EC,Mattow J,Kaufmann SH

更新日期：2001-09-01 00:00:00

abstract：:Cross-reactive humoral immune responses between antigens of different developmental stages of the worm Schistosoma mansoni have previously been demonstrated. In contrast, information on antigenic cross-reactivity at the T-cell level is still very sparse. The present study examined the cross-reactive T-cell responses t...

journal_title：Infection and immunity

authors： Lukacs NW,Boros DL

更新日期：1991-09-01 00:00:00

abstract：:Characteristics of four transmissible gastroenteritis (TGE) virus field strains (Miller, Purdue, Bl, and V203) and four cell culture-attenuated strains (Purdue, SH, CKp, and Bl) were studied to find methods of differentiation between the two groups of viruses. TGE field virus strains did not replicate as well as atten...

journal_title：Infection and immunity

authors： Hess RG,Bachmann PA

更新日期：1976-06-01 00:00:00

abstract：:The region of DNA encoding the mannose-fucose-resistant hemagglutinin (MFRHA) of Vibrio cholerae O1 has been localized, and the nucleotide sequence has been determined. The region contains a single open reading frame encoding 230 amino acids, corresponding to a protein of 26.9 kDa. The N terminus of this protein is at...

journal_title：Infection and immunity

authors： Franzon VL,Barker A,Manning PA

更新日期：1993-07-01 00:00:00

abstract：:In a previous report (Y. Ohmori, S. Hanazawa, S. Amano, T. Miyoshi, K. Hirose, and S. Kitano, infect. Immun. 55:947-954, 1987), we showed that human gingival fibroblasts spontaneously produce thymocyte-activating factor (FTAF), which stimulates mitogen-induced thymocyte proliferation. In the present study, we examined...

journal_title：Infection and immunity

authors： Hanazawa S,Hirose K,Ohmori Y,Amano S,Kitano S

更新日期：1988-01-01 00:00:00

abstract：:Two glucosyltransferase genes from Streptococcus mutans GS-5, gtfB and gtfC, have been previously isolated and sequenced in this laboratory. In the present communication a third gtf gene, gtfD, was isolated and characterized. Isolation of the gene involved a novel procedure utilizing the integration plasmid pVA891. A ...

journal_title：Infection and immunity

authors： Hanada N,Kuramitsu HK

更新日期：1989-07-01 00:00:00

abstract：:Various invasive pathogens attach to host tissues via the extracellular matrix component laminin, the major glycoprotein found within basement membranes. Previous investigations identified the laminin-binding adhesin Tp0751 within the spirochete bacterium Treponema pallidum. In the current study, Tp0751 was shown to a...

journal_title：Infection and immunity

authors： Cameron CE,Brouwer NL,Tisch LM,Kuroiwa JM

更新日期：2005-11-01 00:00:00

abstract：:Genomic DNA fingerprint analysis was performed on 39 Staphylococcus aureus and 28 Enterococcus faecalis endophthalmitis isolates collected from multiple clinical centers. Among 21 S. aureus genomic DNA fingerprint patterns identified, five clonotypes were recovered from multiple unrelated patients and accounted for 58...

journal_title：Infection and immunity

authors： Booth MC,Hatter KL,Miller D,Davis J,Kowalski R,Parke DW,Chodosh J,Jett BD,Callegan MC,Penland R,Gilmore MS

更新日期：1998-01-01 00:00:00

abstract：:Immune responses in the guinea pig model are understudied because of a lack of commercial reagents. We have developed a custom-made guinea pig oligonucleotide microarray (81 spots) and have examined the gene expression profile of splenocytes restimulated in vitro from Mycobacterium bovis BCG-vaccinated and naive anima...

journal_title：Infection and immunity

authors： Tree JA,Elmore MJ,Javed S,Williams A,Marsh PD

更新日期：2006-02-01 00:00:00

abstract：:Patent filarial infection is associated with the downregulation of parasite-specific immune reactivity. In the present study, the relationship between in vitro parasite antigen-specific humoral and cellular immune responsiveness was investigated in Brugia pahangi-infected jirds and in jirds immunized with soluble anti...

journal_title：Infection and immunity

authors： Prier RC,Lammie PJ

更新日期：1988-12-01 00:00:00

abstract：:The study of how bacteria respond to and obtain divalent metal ions provides insight into the regulation of virulence factors in the host environment. Regulation of metal permease operons in gram-positive bacteria may involve the binding of metal-responsive repressors to palindromic domains in their control regions. T...

journal_title：Infection and immunity

authors： Oetjen J,Fives-Taylor P,Froeliger EH

更新日期：2002-10-01 00:00:00

abstract：:Binding of radiolabeled human fibrinogen and aggregated beta-microglobulin was measured in 60 strains of beta-hemolytic group B streptococci. Positive fibrinogen binding was detected in seven of the strains. Six of the group B strains showed an uptake of aggregated beta 2-microglobulin. Four individual strains carried...

journal_title：Infection and immunity

authors： Schönbeck C,Björck L,Kronvall G

更新日期：1981-03-01 00:00:00

abstract：:Comparison of the susceptibility of outbred OF1 and inbred BALB/c, C57BL/6, DBA/2, and CBA mice to heat-stable toxin (STa) of enterotoxigenic Escherichia coli was made at different levels of induced secretion. STa was able to elicit fluid accumulation into the intestine of each strain of mice; however, quantitatively ...

journal_title：Infection and immunity

authors： Bertin A

更新日期：1992-08-01 00:00:00

abstract：:The in vitro effects of pneumolysin, a sulfhydryl-activated toxin produced by Streptococcus pneumoniae, on various functions of human polymorphonuclear leukocytes (PMNLs) was investigated. Treatment of PMNLs with highly purified toxin significantly inhibited respiratory burst (in response to stimulation), ability to k...

journal_title：Infection and immunity

authors： Paton JC,Ferrante A

更新日期：1983-09-01 00:00:00

abstract：:Iron starvation conditions limited the growth of Salmonella typhi, as evidenced by an increase in the lag phase of a culture and a decrease in the number of bacteria reached in the stationary phase. The analysis of the outer membrane of bacteria grown under these conditions identified new protein components with appar...

journal_title：Infection and immunity

authors： Fernandez-Beros ME,Gonzalez C,McIntosh MA,Cabello FC

更新日期：1989-04-01 00:00:00

abstract：:Invasive aspergillosis is a serious fungal infection caused by the proliferation and invasion of Aspergillus hyphae in tissue. Neutrophils (PMNs) are the most important line of defense against Aspergillus hyphae. To investigate the role of granulocyte colony-stimulating factor (G-CSF) and gamma interferon (IFN-gamma) ...

journal_title：Infection and immunity

authors： Roilides E,Uhlig K,Venzon D,Pizzo PA,Walsh TJ

更新日期：1993-04-01 00:00:00

abstract：:A 2.9-kilobase pair locus in Neisseria meningitidis was identified as containing transcriptionally linked open reading frames encoding TolC- and HlyD-like proteins. Although the meningococcal TolC protein was required for extracellular production of the repeats-in-toxin (RTX) FrpC toxin, it could not functionally repl...

journal_title：Infection and immunity

authors： Kamal N,Rouquette-Loughlin C,Shafer WM

更新日期：2007-12-01 00:00:00

abstract：:Staphylococcal alpha-toxin was purified from Staphylococcus aureus growth medium using adsorption chromatography on controlled pore glass beads. Elution of alpha-toxin from the unmodified glass surface of the beads with various anions generally followed the chaotropic series. Alpha-toxin, purified by glass bead chroma...

journal_title：Infection and immunity

authors： Cassidy P,Harshman S

更新日期：1976-03-01 00:00:00

abstract：:Activation of macrophages was assessed in strains of mice inoculated intraperitoneally with 1,000 times the 50% lethal dose of Rickettsia akari. Macrophages from mice resistant to R. akari infection (C3H/HeN, C57BL/10J, and BALB/cN) were nonspecifically tumoricidal 2 to 4 days after rickettsial inoculation. Moreover, ...

journal_title：Infection and immunity

authors： Nacy CA,Meltzer MS

更新日期：1982-06-01 00:00:00

abstract：:Chlorphenesin (3-p-chlorophenoxy-1,2-propanediol), when injected intravenously together with either of two common bacterial antigens, inhibits the antibody response of the rabbit. The antigens studied are those common to Enterobacteriaceae and to gram-positive bacteria. The immunosuppression is contingent upon incubat...

journal_title：Infection and immunity

authors： Whang HY,Neter E

更新日期：1970-07-01 00:00:00

abstract：:We have previously identified two K88ac adhesion receptors (210 and 240 kDa) which are present in membrane preparations from adhesive but not nonadhesive porcine intestinal brush border cells; these adhesin receptors are postulated to be important determinants of the susceptibility of pigs to K88ac+ enterotoxigenic Es...

journal_title：Infection and immunity

authors： Erickson AK,Baker DR,Bosworth BT,Casey TA,Benfield DA,Francis DH

更新日期：1994-12-01 00:00:00

abstract：:Knowledge of whether Mycobacterium tuberculosis resides within a relatively impermeable membrane-bound vacuole or is free within the cytoplasm within its host cell is central to an understanding of the immunobiology of this intracellular parasite but is a matter of controversy. To explore this issue, we assessed the a...

journal_title：Infection and immunity

authors： Clemens DL,Lee BY,Horwitz MA

更新日期：2002-10-01 00:00:00

abstract：:We have previously shown that splenocytes from mice acutely infected with Trypanosoma cruzi exhibit high levels of nitric oxide (NO)-mediated apoptosis. In the present study, we used the gamma interferon (IFN-gamma)-knockout (IFN-gamma(-/-)) mice to investigate the role of IFN-gamma in modulating apoptosis induction a...

journal_title：Infection and immunity

authors： Martins GA,Vieira LQ,Cunha FQ,Silva JS

更新日期：1999-08-01 00:00:00

abstract：:Synthetic peptides and murine monoclonal antibodies were used to map cross-reactive chlamydial epitopes. A species-specific epitope in the central region of variable sequence region 4 abuts the amino-terminal end of a B-serogroup-specific or F/G-serogroup-specific epitope, which in turn abuts known serovar-specific ep...

journal_title：Infection and immunity

authors： Batteiger BE,Lin PM,Jones RB,Van Der Pol BJ

更新日期：1996-07-01 00:00:00

abstract：:A study of the rise and fall in circulating tetanus antitoxin in a group of 15 adults after basic and booster immunization indicates that although individuals vary greatly in their responsiveness to toxoid, the falloff in antitoxin appears to be fractionally constant for each individual, and over periods of 5 to 6 yea...

journal_title：Infection and immunity

authors： Trinca JC

更新日期：1974-07-01 00:00:00

abstract：:In this study we demonstrate the capability of Chlamydia trachomatis to infect cultured human mesothelial cell (MC) monolayers and to induce the production of the proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-8. Seventy-two hours after initial infection, both the procoagulant activity of MC and the act...

journal_title：Infection and immunity

authors： van Westreenen M,Pronk A,Diepersloot RJ,de Groot PG,Leguit P

更新日期：1998-05-01 00:00:00