Perturbation and proinflammatory type activation of V delta 1(+) gamma delta T cells in African children with Plasmodium falciparum malaria.

abstract：:Borrelia burgdorferi, a causative agent of Lyme borreliosis, is a zoonotic pathogen that survives in nutrient-limited environments within a tick, prior to transmission to its mammalian host. Survival under these prolonged nutrient-limited conditions is thought to be similar to survival during stationary phase, which i...

journal_title：Infection and immunity

authors： Fazzino L,Tilly K,Dulebohn DP,Rosa PA

更新日期：2015-12-01 00:00:00

abstract：:We have determined the amounts of specific anti-class 1 outer membrane protein antibodies in sera from 25 patients during the course of systemic meningococcal disease, using purified class 1 protein as the sensitizing antigen in an enzyme-linked immunosorbent assay. The class 1 protein was obtained from a variant of s...

journal_title：Infection and immunity

authors： Guttormsen HK,Wetzler LM,Solberg CO

更新日期：1994-04-01 00:00:00

abstract：:Neutrophils play a major role in defending the periodontium against infection by oral, gram-negative, facultative bacteria, such as Actinobacillus actinomycetemcomitans, Eikenella corrodens, and Capnocytophaga spp. We examined the sensitivity of these bacteria to a mixture of low-molecular-weight peptides and highly p...

journal_title：Infection and immunity

authors： Miyasaki KT,Bodeau AL,Ganz T,Selsted ME,Lehrer RI

更新日期：1990-12-01 00:00:00

abstract：:Based upon the lipopolysaccharide (LPS) structure and antigenicity of Shigella group B, a strategy for broad cross-protection against 14 Shigella flexneri serotypes was designed. This strategy involves the use of two S. flexneri serotypes (2a and 3a), which together bear the all of the major antigenic group factors of...

journal_title：Infection and immunity

authors： Noriega FR,Liao FM,Maneval DR,Ren S,Formal SB,Levine MM

更新日期：1999-02-01 00:00:00

abstract：:The intravascular trematode Schistosoma mansoni is a causative agent of schistosomiasis, a disease that constitutes a major health problem globally. In this study we cloned and characterized the schistosome tegumental phosphodiesterase SmNPP-5 and evaluated its role in parasite virulence. SmNPP-5 is a 52.5-kDa protein...

journal_title：Infection and immunity

authors： Bhardwaj R,Krautz-Peterson G,Da'dara A,Tzipori S,Skelly PJ

更新日期：2011-10-01 00:00:00

abstract：:Our knowledge of pathogenesis has benefited from a better understanding of the roles of specific virulence factors in disease. To determine the role of the virulence factor ZapA, a 54-kDa metalloproteinase of Proteus mirabilis, in prostatitis, rats were infected with either wild-type (WT) P. mirabilis or its isogenic ...

journal_title：Infection and immunity

authors： Phan V,Belas R,Gilmore BF,Ceri H

更新日期：2008-11-01 00:00:00

abstract：:The diphtheria toxin repressor (DtxR) is an iron-dependent regulator of diphtheria toxin production and iron uptake in Corynebacterium diphtheriae. It is activated in vitro by divalent metal ions including Fe2+, Cd2+, Co2+, Mn2+, Ni2+, and Zn2+. We characterized 20 different mutations in dtxR induced by bisulfite muta...

journal_title：Infection and immunity

authors： Wang Z,Schmitt MP,Holmes RK

更新日期：1994-05-01 00:00:00

abstract：:Sensitized mouse spleen cells decrease the spread of herpes simplex virus infection in cell culture lines derived from human and murine tissues. These washed, sensitized cells act alone and additively in combination with antibody to diminish the ability of single virus-infected cells to spread infection to contiguous ...

journal_title：Infection and immunity

authors： Ennis FA

更新日期：1973-06-01 00:00:00

abstract：:Campylobacter rectus is a putative periodontopathogen which expresses a proteinaceous surface layer (S-layer) external to the outer membrane. S-layers are considered to play a protective role for the microorganism in hostile environments. The S-layer proteins from six different C. rectus strains (five human isolates a...

journal_title：Infection and immunity

authors： Nitta H,Holt SC,Ebersole JL

更新日期：1997-02-01 00:00:00

abstract：:A receptor moiety and blood group substance recognized by the O75X adhesin was studied. Well-defined erythrocytes representing different blood group systems and bacterial derivatives carrying plasmid pBJN406 encoding the adhesin were used in a direct hemagglutination assay. We showed that Dr blood group antigen, a com...

journal_title：Infection and immunity

authors： Nowicki B,Moulds J,Hull R,Hull S

更新日期：1988-05-01 00:00:00

abstract：:Counts of acid-fast bacilli were made on homogenates of whole liver, whole spleen, and two femurs of CBA mice killed at various time intervals after intravenous infection with Mycobacterium lepraemurium. The growth curves so obtained showed that the bacillus multiplied faster in bone marrow than in liver or spleen. No...

journal_title：Infection and immunity

authors： Brown IN,Krenzien HN

更新日期：1976-02-01 00:00:00

abstract：:In experimental Leishmania donovani infection in BALB/c mice, initial susceptibility gives way to T-cell-dependent acquired resistance and eventual control over visceral infection. Since various cytokines appear to underlie the host response to Leishmania infection, we examined infected liver tissue for gene expressio...

journal_title：Infection and immunity

authors： Miralles GD,Stoeckle MY,McDermott DF,Finkelman FD,Murray HW

更新日期：1994-03-01 00:00:00

abstract：:The type-specific antigens of group B type Ic (old designation type Ii) streptococci were extracted, purified, and characterized by serological and chemical methods. The Ia antigen, shared by types Ia and Ic, is a polysaccharide composed of 69% galactose and 25% glucosamine (i.e., 31% N-acetyl-glucosamine). However, t...

journal_title：Infection and immunity

authors： Wilkinson HW,Eagon RG

更新日期：1971-11-01 00:00:00

abstract：:Antigen 2 (Ag2), a major immunoreactive component of Coccidioides immitis mycelium- and spherule-phase cell walls, was recently cloned in our laboratory and was shown to elicit T-cell responses in Coccidioides-immune mice. In this investigation, we evaluated recombinant Ag2 (rAg2) and PCR-generated Ag2 truncations for...

journal_title：Infection and immunity

authors： Zhu Y,Tryon V,Magee DM,Cox RA

更新日期：1997-08-01 00:00:00

abstract：:It was demonstrated that complement-coated sheep erythrocytes bind to Candida albicans cells grown in serum-free RPMI 1640 medium. Testing of purified complement components proved that iC3b and C3d were responsible for the reaction, whereas C3b and C3b-H reacted only slightly if at all. Binding occurred only to C. alb...

journal_title：Infection and immunity

authors： Heidenreich F,Dierich MP

更新日期：1985-11-01 00:00:00

abstract：:Knowledge of whether Mycobacterium tuberculosis resides within a relatively impermeable membrane-bound vacuole or is free within the cytoplasm within its host cell is central to an understanding of the immunobiology of this intracellular parasite but is a matter of controversy. To explore this issue, we assessed the a...

journal_title：Infection and immunity

authors： Clemens DL,Lee BY,Horwitz MA

更新日期：2002-10-01 00:00:00

abstract：:Streptococcus mutans, a major oral pathogen responsible for dental caries formation, possesses a variety of mechanisms for survival in the human oral cavity, where the conditions of the external environment are diverse and in a constant state of flux. The formation of biofilms, survival under conditions of acidic pH, ...

journal_title：Infection and immunity

authors： Chong P,Drake L,Biswas I

更新日期：2008-07-01 00:00:00

abstract：:We developed an efficient electrotransformation system for the pathogenic fungus Histoplasma capsulatum and used it to examine the effects of features of the transforming DNA on transformation efficiency and fate of the transforming DNA and to demonstrate fungal expression of two recombinant Escherichia coli genes, hp...

journal_title：Infection and immunity

authors： Woods JP,Heinecke EL,Goldman WE

更新日期：1998-04-01 00:00:00

abstract：:An antiserum, C16, was raised in cattle against freeze-thawed extracts of sporozoites of Theileria parva (Muguga). This antiserum, which neutralizes sporozoite infectivity in vitro, identified theileria-specific antigens having approximate molecular masses of 105, 90, 85, 69, 67, 52, 47, and 43 kilodaltons (kDa) on We...

journal_title：Infection and immunity

authors： Iams KP,Hall R,Webster P,Musoke AJ

更新日期：1990-06-01 00:00:00

abstract：:Uropathogenic Escherichia coli strain J96 carries multiple determinants for fimbrial adhesins. The regulatory protein PapB of P fimbriae has previously been implicated in potential coregulatory events. The focB gene of the F1C fimbria determinant is highly homologous to papB; the translated sequences share 81% identit...

journal_title：Infection and immunity

authors： Lindberg S,Xia Y,Sondén B,Göransson M,Hacker J,Uhlin BE

更新日期：2008-02-01 00:00:00

abstract：:A murine monoclonal antibody was raised against the B95-8 strain of Epstein-Barr virus (EBV), which was isolated from a case of mononucleosis after blood transfusion (Hoffman et al. Proc. Natl. Acad. Sci. U.S.A. 77:2979, 1980). We provide evidence that neutralization of immortalization by this monoclonal antibody is v...

journal_title：Infection and immunity

authors： Miller G,Heston L,Hoffman G

更新日期：1982-09-01 00:00:00

abstract：:The virulence of Neisseria gonorrhoeae for chicken embryos can be modified in a predictable manner by the addition of microbial siderophores to the inoculum. "Meningobactin" and "gonobactin," siderophores isolated from iron-limited cultures of meningococci and gonococci, respectively, enhance the virulence of the rela...

journal_title：Infection and immunity

authors： Finkelstein RA,Yancey RJ

更新日期：1981-05-01 00:00:00

abstract：:C57BL/6J mice infected with Plasmodium berghei ANKA develop neurological dysfunction and die within 7 days of infection. We show that treatment of infected mice with a kynurenine-3-hydroxylase inhibitor prevents them from developing neurological symptoms and extends their life span threefold until severe anemia develo...

journal_title：Infection and immunity

authors： Clark CJ,Mackay GM,Smythe GA,Bustamante S,Stone TW,Phillips RS

更新日期：2005-08-01 00:00:00

abstract：:Using a murine respiratory infection model, we have demonstrated previously that infection with Bordetella pertussis or immunization with a whole-cell pertussis vaccine induced antigen-specific Th1 cells, which conferred a high level of protection against aerosol challenge. In contrast, immunization with an acellular ...

journal_title：Infection and immunity

authors： Mahon BP,Ryan MS,Griffin F,Mills KH

更新日期：1996-12-01 00:00:00

abstract：:Lactoferrin (Lf) is an iron-binding antimicrobial protein present in milk and on mucosal surfaces, with a suggested role in preimmune host defense. Certain strains of Escherichia coli (bacterial whole cells) demonstrate specific interaction with 125I-labeled Lf. A band with a mass of approximately 37 kDa, which was re...

journal_title：Infection and immunity

authors： Erdei J,Forsgren A,Naidu AS

更新日期：1994-04-01 00:00:00

abstract：:Aeromonas salmonicida causes furunculosis in salmonids and is a threat to Atlantic salmon aquaculture. The epithelial surfaces that the pathogen colonizes are covered by a mucus layer predominantly comprised of secreted mucins. By using mass spectrometry to identify mucin glycan structures with and without enzymatic r...

journal_title：Infection and immunity

authors： Padra JT,Sundh H,Sundell K,Venkatakrishnan V,Jin C,Samuelsson T,Karlsson NG,Lindén SK

更新日期：2017-07-19 00:00:00

abstract：:Female mice infected at birth with 10(7) 50% tissue culture infective doses of polyoma virus were mated when at least 6 weeks old. Polyoma was not detected in any tissues of 27 female mice before mating except for trace amounts in the kidneys of 2 mice, but late in gestation polyoma virus could be found in the kidneys...

journal_title：Infection and immunity

authors： McCance DJ,Mims CA

更新日期：1979-09-01 00:00:00

abstract：:Three strains of anaerobic, dextranase-producing, gram-positive, rod-shaped bacteria were isolated from human dental plaque associated with root carious lesions. The isolates produced a molar ratio of acetate to lactate from glucose fermentation ranging from 1.1 to 1.9. Each strain also produced fructose-6-phosphate p...

journal_title：Infection and immunity

authors： Kaster AG,Brown LR

更新日期：1983-11-01 00:00:00

abstract：:Herpes simplex virus (HSV) infection of mouse liver after partial hepatectomy was studied. Partial hepatectomy resulted in the rapid onset of cellular DNA synthesis and the appearance of many mitotic figures (peak, 3 days after surgery). Similar changes were not seen in control animals. After partial hepatectomy, the ...

journal_title：Infection and immunity

authors： Fang ZY,Tenser RB,Rapp F

更新日期：1983-10-01 00:00:00

abstract：:Changes in the structural components of the Streptococcus pyogenes membrane between exponential and early stationary phases of growth are reported. The overall protein composition ranged from 70 to 73% of the dry weight of the membranes, irrespective of the phase of growth from which they were isolated. Amino acid ana...

journal_title：Infection and immunity

authors： van de Rijn I,Kessler RE

更新日期：1979-12-01 00:00:00