Reactivation of polyoma virus in kidneys of persistently infected mice during pregnancy.

abstract：:Neisseria gonorrhoeae is generally considered to be an obligate aerobe; it can, however, grow in the absence of oxygen by anaerobic respiration by using nitrite as a terminal electron acceptor. The outer membrane protein compositions of aerobically and anaerobically grown N. gonorrhoeae strains were compared by one- a...

journal_title：Infection and immunity

authors： Clark VL,Campbell LA,Palermo DA,Evans TM,Klimpel KW

更新日期：1987-06-01 00:00:00

abstract：:The outer membrane protein OmpU of Vibrio cholerae O1 strain 86B3 was characterized with reference to colonization of the intestine by the organism. The purified OmpU exhibited a pI of 3.6. Upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis, it migrated to 38, 32, and 110 kDa when the sample was heated at ...

journal_title：Infection and immunity

authors： Nakasone N,Iwanaga M

更新日期：1998-10-01 00:00:00

abstract：:No effective therapy exists for Cryptosporidium parvum, a coccidial protozoan parasite that causes severe diarrhea in patients with AIDS. The role of microtubules in parasite invasion of host cells was investigated by incubating 10(7) oocysts with a HT 29.74 cell line for 24 h in the presence of microtubule-disrupting...

journal_title：Infection and immunity

authors： Wiest PM,Johnson JH,Flanigan TP

更新日期：1993-11-01 00:00:00

abstract：:Ehrlichia risticii incubated with mouse peritoneal macrophages elicited with thioglycolate broth survived and replicated, thereby allowing examination of the effects of several immunopotentiating agents. Treatment of the macrophages with recombinant murine gamma interferon (rMuIFN-gamma) in vitro at 1 day before or 3 ...

journal_title：Infection and immunity

authors： Park J,Rikihisa Y

更新日期：1991-10-01 00:00:00

abstract：:Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL), SylvioX10/4 (SYL), and a cultured clone (TCC) exhibited differe...

journal_title：Infection and immunity

authors： Zago MP,Hosakote YM,Koo SJ,Dhiman M,Piñeyro MD,Parodi-Talice A,Basombrio MA,Robello C,Garg NJ

更新日期：2016-05-24 00:00:00

abstract：:Paracoccidioidomycosis patients show hyperactive humoral immune responses. Consequently, we investigated whether cytokines in supernatants from Paracoccidioides brasiliensis-stimulated gamma/delta T cells support B-cell activation. We detected proliferation of B cells and increased immunoglobulin M (IgM) and IgG produ...

journal_title：Infection and immunity

authors： Munk ME,Fazioli RA,Calich VL,Kaufmann SH

更新日期：1995-04-01 00:00:00

abstract：:We investigated the effect of a pH 4-treated human immunoglobulin preparation for intravenous use (pH4-G) on the production of tumor necrosis factor alpha (TNF-alpha) in vivo. The level of TNF-alpha in the sera of rabbits receiving pH4-G before lipopolysaccharide (LPS) injection was lower than that in rabbits receivin...

journal_title：Infection and immunity

authors： Shimozato T,Iwata M,Tamura N

更新日期：1990-05-01 00:00:00

abstract：:Enterococcus faecalis strains are resident intestinal bacteria associated with invasive infections, inflammatory bowel diseases, and colon cancer. Although factors promoting E. faecalis colonization of intestines are not fully known, one implicated pathway is a phosphotransferase system (PTS) in E. faecalis strain OG1...

journal_title：Infection and immunity

authors： Fan TJ,Goeser L,Naziripour A,Redinbo MR,Hansen JJ

更新日期：2019-06-20 00:00:00

abstract：:Tuberculosis (TB) remains an enormous global health problem, and a new vaccine against TB more potent than the current inadequate vaccine, Mycobacterium bovis BCG, is urgently needed. We describe a recombinant BCG vaccine (rBCG30) expressing and secreting the 30-kDa major secretory protein of Mycobacterium tuberculosi...

journal_title：Infection and immunity

authors： Horwitz MA,Harth G

更新日期：2003-04-01 00:00:00

abstract：:Neonates are at increased risk for bacterial sepsis. We established that the immune-suppressive cytokine interleukin-27 (IL-27) is elevated in neonatal mice. Similarly, human cord blood-derived macrophages express IL-27 genes and secrete more cytokine than macrophages from adults. In the present work, we hypothesized ...

journal_title：Infection and immunity

authors： Seman BG,Vance JK,Rawson TW,Witt MR,Huckaby AB,Povroznik JM,Bradford SD,Barbier M,Robinson CM

更新日期：2020-02-20 00:00:00

abstract：:We have previously shown that Bacillus anthracis lethal toxin represses glucocorticoid receptor (GR) transactivation. We now report that repression of GR activity also occurs with the large clostridial toxins produced by Clostridium sordellii and C. difficile. This was demonstrated using a transient transfection assay...

journal_title：Infection and immunity

authors： Tait AS,Dalton M,Geny B,D'Agnillo F,Popoff MR,Sternberg EM

更新日期：2007-08-01 00:00:00

abstract：:Studies conducted with F1 and F2 progeny of crosses between strains of inbred mice that differ greatly in their capacity to make an antibody response to type III pneumococcal polysaccharide, dextran B-1355, and lipopolysaccharide from Escherichia coli 0113 have shown that multiple genes influence the magnitude of the ...

journal_title：Infection and immunity

authors： Baker PJ,Rudbach JA,Prescott B,Caldes G,Evans C,Stashak PW

更新日期：1984-07-01 00:00:00

abstract：:The mechanism by which bacterial heat-stable enterotoxins (ST I STA) cause diarrhea in humans and animals has been linked to the activation of an intestinal membrane-bound guanylate cyclase. Guanylin, a recently discovered rat intestinal peptide, is homologous in structure to ST I and can activate guanylate cyclase pr...

journal_title：Infection and immunity

authors： Carpick BW,Gariépy J

更新日期：1993-11-01 00:00:00

abstract：:Results of earlier investigations have indicated that the saprobic phase of Coccidioides immitis produces a heat-stable, 19-kDa antigen with serine proteinase activity which has been suggested to be specific for this pathogenic fungus. In the present study we have determined the N-terminal and partial internal amino a...

journal_title：Infection and immunity

authors： Pan S,Cole GT

更新日期：1995-10-01 00:00:00

abstract：:The amino acid sequence of heat-stable enterotoxin produced by enterotoxigenic Escherichia coli 18D has been revised. Amino acids originally assigned to positions 11 and 18, i.e., Tyr and Asn, respectively, were found to occupy positions 18 and 11, respectively. Thus all heat-stable enterotoxins composed of 18 amino a...

journal_title：Infection and immunity

authors： Thompson MR,Giannella RA

更新日期：1985-03-01 00:00:00

abstract：:Cigarette smoke exposure increases the risk of pulmonary and invasive infections caused by Streptococcus pneumoniae, the most commonly isolated organism from patients with community-acquired pneumonia. Despite this association, the mechanisms by which cigarette smoke exposure diminishes host defense against S. pneumon...

journal_title：Infection and immunity

authors： Phipps JC,Aronoff DM,Curtis JL,Goel D,O'Brien E,Mancuso P

更新日期：2010-03-01 00:00:00

abstract：:Mucosa-associated invariant T (MAIT) cells are an innate-like T cell subset in mammals that recognize microbial vitamin B metabolites presented by the evolutionarily conserved major histocompatibility complex class I (MHC I)-related molecule, MR1. Emerging data suggest that MAIT cells may be an attractive target for v...

journal_title：Infection and immunity

authors： Vorkas CK,Levy O,Skular M,Li K,Aubé J,Glickman MS

更新日期：2020-12-15 00:00:00

abstract：:Various features of salmonellosis were examined in a burned-mouse model. In this model, which uses an outbred mouse strain, a challenge dose of ca. 100 CFU with any of several strains of Salmonella typhimurium caused a fatal infection. A variety of mutated strains attenuated for virulence in Salmonella-susceptible par...

journal_title：Infection and immunity

authors： Carsiotis M,Stocker BA,Holder IA

更新日期：1989-09-01 00:00:00

abstract：:The effect of continuous exposure to 80% oxygen on newborn mice with Ureaplasma urealyticum pneumonia was determined. Mice were inoculated intranasally with either U. urealyticum or sterile broth and then housed in either 80% oxygen or room air (21% oxygen). The mice were sacrificed at either 7 or 14 days after inocul...

journal_title：Infection and immunity

authors： Crouse DT,Cassell GH,Waites KB,Foster JM,Cassady G

更新日期：1990-11-01 00:00:00

abstract：:The production and role of tumor necrosis factor alpha (TNF-alpha) in pneumococcal pneumonia were investigated in a mouse pneumonia model. When approximately 10(6) CFU of Streptococcus pneumoniae TUM19 were used to inoculate CBA/J mice intranasally, TNF-alpha levels in the lungs and serum began to increase from 1 and ...

journal_title：Infection and immunity

authors： Takashima K,Tateda K,Matsumoto T,Iizawa Y,Nakao M,Yamaguchi K

更新日期：1997-01-01 00:00:00

abstract：:This study compared infection and transformation of peripheral blood mononuclear cells (PBM) of Boran cattle and African buffalo in vitro to determine whether differences occurred which could account for the greater susceptibility of Boran cattle to infection with Theileria parva subsp. parva and T. parva subsp. lawre...

journal_title：Infection and immunity

authors： Baldwin CL,Malu MN,Kinuthia SW,Conrad PA,Grootenhuis JG

更新日期：1986-07-01 00:00:00

abstract：:Groups of female C57BL/6 and C3H/St mice were inoculated intraperitoneally (i.p.) with 10(9), 10(7), and 10(5) bacilli and into the right hind footpad with 10(7) and 10(5) bacilli of Mycobacterium lepraemurium. The incidence of death from leprosy and the mean survival time of leprous mice were recorded. In addition, t...

journal_title：Infection and immunity

authors： Turcotte R

更新日期：1980-06-01 00:00:00

abstract：:Growth of a streptomycin-resistant strain of Escherichia coli (VL-2) in the presence of 30 microgram of streptomycin per ml resulted in the production by these bacteria of structurally altered, nonfunctional type 1 fimbriae. This strain, when grown in this subinhibitory concentration of streptomycin, became incapable ...

journal_title：Infection and immunity

authors： Eisenstein BI,Ofek I,Beachey EH

更新日期：1981-02-01 00:00:00

abstract：:Among a number of laboratory strains of Listeria monocytogenes used in experimental infection, strain LO28 is highly capable of inducing robust beta interferon (IFN-β) production in infected macrophages. In this study, we investigated the molecular mechanism of the IFN-β-inducing ability of LO28 by comparing it with t...

journal_title：Infection and immunity

authors： Yamamoto T,Hara H,Tsuchiya K,Sakai S,Fang R,Matsuura M,Nomura T,Sato F,Mitsuyama M,Kawamura I

更新日期：2012-07-01 00:00:00

abstract：:In order to approximate and adhere to mucosal epithelial cells, Candida must traverse the overlying mucus layer. Interactions of Candida species with mucin and human buccal epithelial cells (BECs) were thus investigated in vitro. Binding of the Candida species to purified small intestinal mucin showed a close correlat...

journal_title：Infection and immunity

authors： de Repentigny L,Aumont F,Bernard K,Belhumeur P

更新日期：2000-06-01 00:00:00

abstract：:We measured the microbicidal peptides MCP-1 and MCP-2 in rabbit alveolar macrophages (AM), comparing rabbits pretreated with complete Freund adjuvant with untreated control animals. Levels of MCP-1 increased from 4.7 +/- 0.6 microgram/10(7) resident AM to 13.2 +/- 0.1 microgram/10(7) complete Freund adjuvant-elicited ...

journal_title：Infection and immunity

authors： Lehrer RI,Szklarek D,Selsted ME,Fleischmann J

更新日期：1981-09-01 00:00:00

abstract：:Meningococcal sodC encodes periplasmic copper- and zinc-cofactored superoxide dismutase (Cu,Zn SOD) which catalyzes the conversion of the superoxide radical anion to hydrogen peroxide, preventing a sequence of reactions leading to production of toxic hydroxyl free radicals. From its periplasmic location, Cu,Zn SOD was...

journal_title：Infection and immunity

authors： Wilks KE,Dunn KL,Farrant JL,Reddin KM,Gorringe AR,Langford PR,Kroll JS

更新日期：1998-01-01 00:00:00

abstract：:The urease gene cluster from the virulent Actinobacillus pleuropneumoniae serotype 1 strain CM5 was cloned and sequenced. The urease activity was associated with a 6.3-kbp region which contains eight long open reading frames (ORFs). The structural genes, ureABC, are separated from the accessory genes, ureEFGD, by a 61...

journal_title：Infection and immunity

authors： Bossé JT,MacInnes JI

更新日期：1997-11-01 00:00:00

abstract：:We have previously demonstrated that fibronectin mediates streptococcal adhesion to host cells and that streptococci interact primarily with the N-terminal domain of fibronectin. FBP54 is a 54-kDa protein from group A streptococci that binds fibronectin. In this report, we show that the N-terminal domain of fibronecti...

journal_title：Infection and immunity

authors： Courtney HS,Dale JB,Hasty DI

更新日期：1996-07-01 00:00:00

abstract：:The ocular damage in young adult mice produced by purified Pseudomonas aeruginosa exotoxin A was microscopically characterized at 1 and 5 h and at 1, 3, 5, 7, 10, 14, and 21 days after toxin A challenge, using light, transmission, and scanning electron microscopic techniques. Similarly to previously described infectio...

journal_title：Infection and immunity

authors： Hazlett LD,Berk RS,Iglewski BH

更新日期：1981-12-01 00:00:00