Paracoccidioides brasiliensis-stimulated human gamma/delta T cells support antibody production by B cells.

Abstract:

:Paracoccidioidomycosis patients show hyperactive humoral immune responses. Consequently, we investigated whether cytokines in supernatants from Paracoccidioides brasiliensis-stimulated gamma/delta T cells support B-cell activation. We detected proliferation of B cells and increased immunoglobulin M (IgM) and IgG production. Thus, gamma/delta T cells may participate in polyclonal B-cell activation during paracoccidioidomycosis.

journal_name

Infect Immun

journal_title

Infection and immunity

authors

Munk ME,Fazioli RA,Calich VL,Kaufmann SH

doi

10.1128/IAI.63.4.1608-1610.1995

subject

Has Abstract

pub_date

1995-04-01 00:00:00

pages

1608-10

issue

4

eissn

0019-9567

issn

1098-5522

journal_volume

63

pub_type

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