Preclinical immunoprophylactic and immunotherapeutic efficacy of antisera to capsular polysaccharide-tetanus toxoid conjugate vaccines of Vibrio vulnificus.

abstract：:Intravenous injection of rat anti-mouse gamma interferon (IFN-gamma) monoclonal antibody as well as rabbit anti-mouse tumor necrosis factor (TNF) antibody into mice which had received a sublethal infection with Listeria monocytogenes cells resulted in acceleration of listeriosis. Endogenous IFN-gamma seemed to be prod...

journal_title：Infection and immunity

authors： Nakane A,Minagawa T,Kohanawa M,Chen Y,Sato H,Moriyama M,Tsuruoka N

更新日期：1989-11-01 00:00:00

abstract：:Four classes of mutants of type III group B streptococcus were isolated by serial subculture of the wild-type strain in the presence of type III-specific rabbit antiserum. Class I mutants no longer synthesized sialic acid but still elaborated the core antigen. Class II mutants maintained the ability to synthesize sial...

journal_title：Infection and immunity

authors： Yeung MK,Mattingly SJ

更新日期：1983-10-01 00:00:00

abstract：:The symptoms of Lyme disease are caused by inflammation induced by species of the Borrelia burgdorferisensu lato complex. The various presentations of Lyme disease in the population suggest that differences exist in the intensity and regulation of the host response to the spirochete. Previous work has described correl...

journal_title：Infection and immunity

authors： Siebers EM,Liedhegner ES,Lawlor MW,Schell RF,Nardelli DT

更新日期：2020-10-19 00:00:00

abstract：:Lipopolysaccharide (LPS) binding protein (LBP) is an acute-phase protein that enhances the responsiveness of immune cells to LPS by virtue of its capacity to transfer LPS to CD14. To determine the role of LBP in the innate immune response to peritonitis, LBP gene-deficient (LBP(-/-)) and normal wild-type mice were int...

journal_title：Infection and immunity

authors： Knapp S,de Vos AF,Florquin S,Golenbock DT,van der Poll T

更新日期：2003-12-01 00:00:00

abstract：:Nonimmune binding of immunoglobulin to whole bacteria was quantitated for North American isolates of Haemophilus somnus recovered from cattle with pneumonia, reproductive failure (abortion), or thromboembolic meningoencephalitis or from the vagina or prepuce of carrier cattle. Quantitative binding activity covered a w...

journal_title：Infection and immunity

authors： Widders PR,Dorrance LA,Yarnall M,Corbeil LB

更新日期：1989-02-01 00:00:00

abstract：:A cohort of 111 children from Bangui, Central African Republic, was surveyed for enteric Campylobacter infections from birth to the age of 2 years; stools were examined biweekly in these children until 6 months of age and at least four times per year thereafter until 2 years of age and after each diarrheal episode. Bl...

journal_title：Infection and immunity

authors： Martin PM,Mathiot J,Ipero J,Kirimat M,Georges AJ,Georges-Courbot MC

更新日期：1989-08-01 00:00:00

abstract：:Lymphocyte blastogenesis assays and immunoblotting were used to investigate and compare murine B-cell responses to preparations of extracellular membrane blebs (BAg) and spirochetes (Ag) of Borrelia burgdorferi. Immunoblotting BAg, Ag, and medium control preparations with serum from naive and infected C57BL/10 mice re...

journal_title：Infection and immunity

authors： Whitmire WM,Garon CF

更新日期：1993-04-01 00:00:00

abstract：:Intrakingdom cell-to-cell communication and interkingdom cell-to-cell communication play essential roles in the virulence of enterohemorrhagic Escherichia coli (EHEC). Four signals, autoinducer 2 (AI-2), AI-3, and the human hormones epinephrine and norepinephrine, are important in this communication. The effect of the...

journal_title：Infection and immunity

authors： Kendall MM,Rasko DA,Sperandio V

更新日期：2007-10-01 00:00:00

abstract：:Groups of specific pathogen-free Hartley strain guinea pigs were vaccinated with viable Mycobacterium bovis BCG and maintained on isocaloric purified diets containing either 30 or 10% protein (ovalbumin) combined with either 50 ppm (microgram/g) or no added zinc. Seven weeks later the guinea pigs were skin tested with...

journal_title：Infection and immunity

authors： McMurray DN,Yetley EA

更新日期：1983-02-01 00:00:00

abstract：:With a purified beta-propiolactone-inactivated rabies virus, a significant increase in footpad swelling was elicited in normal or in BCG-pretreated mice after immunization with varying doses of rabies vaccine. These footpad reactions were shown to peak at 24 h and to be associated with an infiltration of newly formed ...

journal_title：Infection and immunity

authors： Lagrange PH,Tsiang H,Hurtrel B,Ravisse P

更新日期：1978-09-01 00:00:00

abstract：:Attention has recently been focused on immunoglobulin A1 (IgA1) protease production as a possible virulence factor of bacteria implicated in meningitis and gonorrhea. This report demonstrates that suspected principal etiological agents in destructive periodontal disease include bacteria capable of degrading IgA1, IgA2...

journal_title：Infection and immunity

authors： Kilian M

更新日期：1981-12-01 00:00:00

abstract：:A simple and convenient method was developed for the preparation of Streptococcus pneumoniae type 14 polysaccharide (Pn14PS)-tetanus toxoid (TT) conjugate vaccines, using terminally linked Pn14PS fragments of different lengths. Native Pn14PS was simultaneously depolymerized and activated for conjugation by partial N-d...

journal_title：Infection and immunity

authors： Laferriere CA,Sood RK,de Muys JM,Michon F,Jennings HJ

更新日期：1998-06-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4), which recognizes lipopolysaccharide from Gram-negative bacteria, plays a major role in resistance of mice and humans to Salmonella infection. In chickens, Salmonella may establish a carrier state whereby bacteria are able to persist in the host organism without triggering clinical signs. B...

journal_title：Infection and immunity

authors： Chaussé AM,Grépinet O,Bottreau E,Le Vern Y,Menanteau P,Trotereau J,Robert V,Wu Z,Kerboeuf D,Beaumont C,Velge P

更新日期：2011-08-01 00:00:00

abstract：:We have previously shown that a Pasteurella multocida cexA mutant (PBA875) was impaired in capsule export and highly attenuated in virulence for mice (J. D. Boyce and B. Adler, Infect. Immun. 68:3463-3468, 2000). In this study we show that immunization with high, but not low, doses of PBA875 can confer significant pro...

journal_title：Infection and immunity

authors： Boyce JD,Adler B

更新日期：2001-03-01 00:00:00

abstract：:A C3d-binding glycoprotein was purified from the culture filtrate of Candida albicans by preparative isoelectric focusing. The protein possessed a pI of 3.9 to 4.1 and could inhibit rosetting of EAC3d (sheep erythrocytes conjugated to C3d) by pseudohyphae of C. albicans. When analyzed by polyacrylamide gel electrophor...

journal_title：Infection and immunity

authors： Saxena A,Calderone R

更新日期：1990-02-01 00:00:00

abstract：:Since secondary Streptococcus pneumoniae infections greatly increase the mortality of influenza infections, we determined the relative roles of neutrophil-dependent and -independent mechanisms in increased susceptibility to S. pneumoniae during influenza infection. Mice infected with influenza for 6 days, but not 3 da...

journal_title：Infection and immunity

authors： McNamee LA,Harmsen AG

更新日期：2006-12-01 00:00:00

abstract：:Pregnant mice, guinea pigs, rats, and rabbits responded to injections of Moraxella bovis strain EPP-63(300) with abortion, death, embryo resorption, and production of small litters. The nature of response appeared to depend primarily on the number of viable cells injected and to some extent on the species of animal an...

journal_title：Infection and immunity

authors： Norman JO,Elissalde MH

更新日期：1979-05-01 00:00:00

abstract：:Twenty monoclonal antibodies have been prepared to the erythrocytes from CBA/Ca mice infected with the rodent malaria Plasmodium chabaudi. By immunofluorescence, 15 of these antibodies recognized parasite antigens expressed only during the development of mature trophozoites to schizonts and merozoites, 2 recognized pa...

journal_title：Infection and immunity

authors： Boyle DB,Newbold CI,Smith CC,Brown KN

更新日期：1982-10-01 00:00:00

abstract：:Gram-negative bacterial cells exposed to a complement source may carry membrane attack complexes containing variable numbers of C9 molecules per C5b-8 site. In order to investigate the assembly of this complex, the ability of C9 molecules to bind to C5b-8 complexes was compared with the binding characteristics of C9 f...

journal_title：Infection and immunity

authors： MacKay SL,Dankert JR

更新日期：1994-07-01 00:00:00

abstract：:Yersinia pestis KIM5 was found to be cytotoxic for the IC21 and P388D1 mouse macrophage cell lines, as well as for resident peritoneal macrophages from C57BL/6 mice. Affected cells phagocytosed KIM5 inefficiently, became spherical, detached readily from culture dishes, and retained 51Cr poorly. The cytotoxic effect wa...

journal_title：Infection and immunity

authors： Goguen JD,Walker WS,Hatch TP,Yother J

更新日期：1986-03-01 00:00:00

abstract：:An immunosuppressed rat model of Pneumocystis carinii pneumonia is described that utilizes simple, noninvasive intratracheal (i.t.) inoculation of cryopreserved parasites and results in development of severe P. carinii pneumonia within 5 weeks. This is an improvement over the most commonly used models of P. carinii pn...

journal_title：Infection and immunity

authors： Boylan CJ,Current WL

更新日期：1992-04-01 00:00:00

abstract：:Transposon Tn916 was used to insertionally inactivate a coaggregation-relevant locus of Streptococcus gordonii DL1 (Challis). One mutant (F11) was isolated that lost the ability to coaggregate with the streptococcal partners of DL1 but retained the ability to coaggregate with partners belonging to other genera. A prob...

journal_title：Infection and immunity

authors： Whittaker CJ,Clemans DL,Kolenbrander PE

更新日期：1996-10-01 00:00:00

abstract：:In this study we have characterized the association of a polysaccharide-deficient, lipid-rich lipopolysaccharide (LPS) with rabbit erythrocytes (RaRBC). With polymyxin B sulfate-mediated hemolysis as a probe, we have shown that Salmonella minnesota R595 LPS interacts with RaRBC in two distinguishable steps. The first ...

journal_title：Infection and immunity

authors： Carr C Jr,Morrison DC

更新日期：1984-02-01 00:00:00

abstract：:Most oral bacteria tested formed colonies on a chemically defined medium with a chromogenic arylsulfatase substrate. Arylsulfatase activity was, however, restricted to Campylobacter-Wolinella group organisms, including Wolinella recta, a possible periodontopathogen. W. recta was the only arylsulfatase-active species a...

journal_title：Infection and immunity

authors： Wyss C

更新日期：1989-05-01 00:00:00

abstract：:Hypoferremia, the reduction of plasma transferrin iron levels during infection, has been shown to control Neisseria meningitidis infection in mice. The exact nature of the mechanism that regulates this response has been obscure. We have previously shown that hypoferremia does not result from an accelerated removal of ...

journal_title：Infection and immunity

authors： Letendre ED,Holbein BE

更新日期：1984-05-01 00:00:00

abstract：:Invasive aspergillosis is a serious fungal infection caused by the proliferation and invasion of Aspergillus hyphae in tissue. Neutrophils (PMNs) are the most important line of defense against Aspergillus hyphae. To investigate the role of granulocyte colony-stimulating factor (G-CSF) and gamma interferon (IFN-gamma) ...

journal_title：Infection and immunity

authors： Roilides E,Uhlig K,Venzon D,Pizzo PA,Walsh TJ

更新日期：1993-04-01 00:00:00

abstract：:In studies of experimental Lyme disease, a major obstacle has been the unavailability of a suitable animal model. We found that irradiated LSH/Ss Lak hamsters developed arthritis after injection of Borrelia burgdorferi in the hind paws. When nonirradiated hamsters were injected in the hind paws with B. burgdorferi, ac...

journal_title：Infection and immunity

authors： Schmitz JL,Schell RF,Hejka A,England DM,Konick L

更新日期：1988-09-01 00:00:00

abstract：:Ocular inflammation is one of the consequences of infection with the protozoan parasite Toxoplasma gondii. Even if lesions are self-healing in immunocompetent persons, they pose a lifetime risk of reactivation and are a serious threat to vision. As there are virtually no immunological data on reactivating ocular toxop...

journal_title：Infection and immunity

authors： Rochet É,Brunet J,Sabou M,Marcellin L,Bourcier T,Candolfi E,Pfaff AW

更新日期：2015-05-01 00:00:00

abstract：:Infection of C3H mice with Borrelia burgdorferi, the causative agent of Lyme disease, reliably produces an infectious arthritis and carditis that peak around 3 weeks postinfection and then spontaneously resolve. Macrophage polarization has been suggested to drive inflammation, the clearance of bacteria, and tissue rep...

journal_title：Infection and immunity

authors： Lasky CE,Olson RM,Brown CR

更新日期：2015-07-01 00:00:00

abstract：:The ability of various strains of rats to produce interferon in response to polyriboinosinic-polyribocytodilic acid was investigated. ACI and DA (RT-1a), BN (RT-1n), Buffalo (RT-1b), August (RT-1c), and GH (RT-1l) strains produced low levels of interferon in response to intraperitoneal administration of polyriboinosin...

journal_title：Infection and immunity

authors： Davis CT,Blankenhorn EP,Murasko DM

更新日期：1984-02-01 00:00:00