Interactions between endogenous gamma interferon and tumor necrosis factor in host resistance against primary and secondary Listeria monocytogenes infections.

abstract：:Bovine NK cells have recently been characterized and the present study describes the interaction between NK cells, antigen-presenting cells, and secreted mycobacterial proteins. Gamma interferon (IFN-gamma) production by NK cells was seen in approximately 30% of noninfected calves in response to the Mycobacterium tube...

journal_title：Infection and immunity

authors： Olsen I,Boysen P,Kulberg S,Hope JC,Jungersen G,Storset AK

更新日期：2005-09-01 00:00:00

abstract：:A2G mice are genetically resistant to lethal infection with neurotropic and pneumotropic influenza viruses. A possible immunological explanation for this resistance was sought by assessing the effect of cyclophosphamide and X irradiation immunosuppression on the infection of A2G mice with lethal doses of neurovirulent...

journal_title：Infection and immunity

authors： Fiske RA,Klein PA

更新日期：1975-03-01 00:00:00

abstract：:Mutant cultures that lacked the ability to produce filamentous hemagglutinin were obtained by UV irradiation of Bordetella pertussis strain 18-323. Various biological activities of these mutants were compared with those of the parent culture. It was found that the leukocytosis-promoting, histamine-sensitizing, and mou...

journal_title：Infection and immunity

authors： Watanabe M,Nakase Y

更新日期：1982-03-01 00:00:00

abstract：:The antiinflammatory cytokine response during urosepsis was determined by measurement of concentrations of soluble tumor necrosis factor receptor (sTNFR) types I and II, interleukin 1 receptor antagonist (IL-1ra), soluble IL-1 receptor type II (sIL-1RII), and interleukin 10 in sera and urine of 30 patients with cultur...

journal_title：Infection and immunity

authors： Olszyna DP,Prins JM,Buis B,van Deventer SJ,Speelman P,van der Poll T

更新日期：1998-08-01 00:00:00

abstract：:The P8 proteoglycolipid complex (P8 PGLC) is a glyconjugate expressed by Leishmania mexicana complex parasites. We previously have shown that vaccination with P8 PGLC provides protection against cutaneous leishmaniasis in susceptible BALB/c mice. However, the biological importance of this complex remains unknown. Here...

journal_title：Infection and immunity

authors： Whitaker SM,Colmenares M,Pestana KG,McMahon-Pratt D

更新日期：2008-05-01 00:00:00

abstract：:Help from CD4 T cells is often important for the establishment of primary and memory CD8 T-cell responses. However, it has yet to be determined whether T helper polarization affects the delivery of help and/or whether responding CD8 T cells helped by Th1 or Th2 cells express distinct effector properties. To address th...

journal_title：Infection and immunity

authors： Ekkens MJ,Shedlock DJ,Jung E,Troy A,Pearce EL,Shen H,Pearce EJ

更新日期：2007-05-01 00:00:00

abstract：:The protection and immune response to infection caused by the parasite Schistosoma mansoni were studied by comparison of two murine irradiated-vaccine models. Mice were exposed from 1 to 4 times to infective-stage cercariae attenuated with either a moderate dose (15 kilorads) or a high dose (50 kilorads) of radiation....

journal_title：Infection and immunity

authors： Reynolds SR,Harn DA

更新日期：1992-01-01 00:00:00

abstract：:An impressive change in the epidemiology and severity of invasive group A streptococcal infections occurred in the 1980s, and the incidence of streptococcal toxic shock syndrome cases continues to rise. The reason for the resurgence of severe invasive cases remains a mystery-has there been a change in the pathogen or ...

journal_title：Infection and immunity

authors： Basma H,Norrby-Teglund A,Guedez Y,McGeer A,Low DE,El-Ahmedy O,Schwartz B,Kotb M

更新日期：1999-04-01 00:00:00

abstract：:One mechanism by which interferons (IFNs) can inhibit chlamydial infection is by the induction of the enzyme indoleamine 2,3-dioxygenase (IDO), which restricts the availability of tryptophan, which is required for chlamydial growth. Other immunomodulating agents, including interleukin-1 (IL-1), can interact synergisti...

journal_title：Infection and immunity

authors： Carlin JM,Weller JB

更新日期：1995-05-01 00:00:00

abstract：:Production of interleukin-10 (IL-10) by C57BL/6 mice following infection with Borrelia burgdorferi has been proposed as a mechanism whereby resistance to the development of experimental Lyme arthritis is maintained. In the current study, we sought to determine the role of IL-10 during infection of arthritis- and cardi...

journal_title：Infection and immunity

authors： Brown CR,Lai AY,Callen ST,Blaho VA,Hughes JM,Mitchell WJ

更新日期：2008-12-01 00:00:00

abstract：:Bacteroides spp. may contribute to the chronicity of mixed infections by affecting the normal functions of polymorphonuclear leukocytes (PMN). This study evaluated the physiologic and biochemical responses of human peripheral blood PMN to a variety of strains of the oral periodontal pathogen Porphyromonas (Bacteroides...

journal_title：Infection and immunity

authors： Novak MJ,Cohen HJ

更新日期：1991-09-01 00:00:00

abstract：:Intact tissues are relatively resistant to Pseudomonas aeruginosa-induced disease, and injury predisposes tissue to infection. Intact epithelia contain polarized cells that have distinct apical and basolateral membranes with unique lipids and proteins. In this study, the role of cell polarity in epithelial cell suscep...

journal_title：Infection and immunity

authors： Fleiszig SM,Evans DJ,Do N,Vallas V,Shin S,Mostov KE

更新日期：1997-07-01 00:00:00

abstract：:Evidence is presented to indicate that Plasmodium berghei merozoites, but not trophozotites, have an antiphagocytic capsule. The capsule appears to form around the developing merozoties of the schizont in the parasitophorous vacuole. Serum from animals immune to P. berghei reacts with this capsule. After reaction with...

journal_title：Infection and immunity

authors： Brooks C,Kreier JP

更新日期：1978-06-01 00:00:00

abstract：:The expression of the Shigella flexneri chromosomal aerobactin genes during growth of the bacterium within tissue culture cells was assayed. During intracellular growth, aerobactin promoter activity was repressed relative to the level observed in bacteria grown extracellularly, even when the bacteria had been starved ...

journal_title：Infection and immunity

authors： Headley V,Hong M,Galko M,Payne SM

更新日期：1997-02-01 00:00:00

abstract：:We have developed an animal model for studying mycobacterial pathogenesis using Mycobacterium marinum and the goldfish, Carassius auratus. Goldfish are injected intraperitoneally with doses between 10(2) and 10(9) CFU of M. marinum organisms. Depending on the dose of M. marinum organisms administered, an acute or chro...

journal_title：Infection and immunity

authors： Talaat AM,Reimschuessel R,Wasserman SS,Trucksis M

更新日期：1998-06-01 00:00:00

abstract：:Temperate bacteriophage can transfer toxin-encoding genes between bacteria, often resulting in acquired pathogenicity. However, little is known regarding the effects of the eukaryotic host on the phage-pathogen interaction. Using Streptococcus pyogenes as a model, we demonstrate, both in vitro and in vivo, that the eu...

journal_title：Infection and immunity

authors： Broudy TB,Fischetti VA

更新日期：2003-07-01 00:00:00

abstract：:Guinea pig and mouse peritoneal macrophages in culture transport glucose by a specific, saturable system with characteristics compatible with facilitated diffusion. Phagocytosis of killed staphylococci or polystyrene latex spheres results in a significant increase in uptake of 2-deoxy-d-glucose. Reciprocal plot analys...

journal_title：Infection and immunity

authors： Bonventre PF,Mukkada AJ

更新日期：1974-12-01 00:00:00

abstract：:In the present investigation we studied the nature of a Shigella flexneri O antigen, the type III antigen. No structural entity has yet been attributed to this antigen. Phenol-water-extracted lipopolysaccharides (LPSs) from all S. flexneri serotypes possessing either group 6 antigen or both type III antigen and group ...

journal_title：Infection and immunity

authors： Carlin NI,Wehler T,Lindberg AA

更新日期：1986-07-01 00:00:00

abstract：:Preliminary studies established methods for obtaining maximum yields of viable cells. Liquid shaken cultures of Histoplasma capsulatum provided a maximum of 4 x 10(8) to 5 x 10(8) cells/ml regardless of the inoculum size. Under optimum conditions, cells were viable (90 to 95%) for 168 to 240 hr. Generation times range...

journal_title：Infection and immunity

authors： Garcia JP,Howard DH

更新日期：1971-08-01 00:00:00

abstract：:The pH 6 antigen (Psa) of Yersinia pestis consists of fimbriae with adhesive properties of potential importance for the pathogenesis of plague, including pneumonic plague. The Psa fimbriae mediate bacterial binding to human alveolar epithelial cells. The Psa fimbriae bound mostly to one component present in the total ...

journal_title：Infection and immunity

authors： Galván EM,Chen H,Schifferli DM

更新日期：2007-03-01 00:00:00

abstract：:Escherichia coli isolates from patients with bacteriuria of pregnancy were compared by PCR with isolates from patients with community-acquired cystitis for the presence of established virulence determinants. The strains from patients with bacteriuria of pregnancy were less likely to carry genes for P-family, S-family,...

journal_title：Infection and immunity

authors： Graham JC,Leathart JB,Keegan SJ,Pearson J,Bint A,Gally DL

更新日期：2001-02-01 00:00:00

abstract：:Previously, we isolated a high-molecular-weight immunogenic polysaccharide (designated PS) from Pseudomonas aeruginosa immunotype 1 (IT-1). The method which we used was modified to permit the isolation of a similar PS from P. aeruginosa IT-2. This antigen was composed primarily of carbohydrate, had a complex monosacch...

journal_title：Infection and immunity

authors： Pier GB,Sidberry HF,Sadoff JC

更新日期：1981-11-01 00:00:00

abstract：:Mucosal immune responses to fungal infection range from T helper type 2 (Th2) cell-directed allergic inflammation to Th1-predominant neutrophilic inflammation, but the mechanisms directing these divergent mucosal immune outcomes and the role of T cells in host defense against mucosal fungal infections are not known. H...

journal_title：Infection and immunity

authors： Porter PC,Roberts L,Fields A,Knight M,Qian Y,Delclos GL,Han S,Kheradmand F,Corry DB

更新日期：2011-11-01 00:00:00

abstract：:The Burkholderia cepacia epidemic strain marker (BCESM) is a useful epidemiological marker for virulent B. cenocepacia strains that infect patients with cystic fibrosis. However, there was no evidence that the original marker, identified by random amplified polymorphic DNA fingerprinting, contributed to pathogenicity....

journal_title：Infection and immunity

authors： Baldwin A,Sokol PA,Parkhill J,Mahenthiralingam E

更新日期：2004-03-01 00:00:00

abstract：:The guinea pig migration inhibition technique, an accepted in vitro correlate of delayed hypersensitivity, has been adapted to a murine system. Peritoneal exudate cells from CF-1 mice vaccinated with viable cells of the H37Ra strain of Mycobacterium tuberculosis were inhibited in vitro by purified protein derivative (...

journal_title：Infection and immunity

authors： Neiburger RG,Youmans GP

更新日期：1973-02-01 00:00:00

abstract：:Chlamydia trachomatis is an obligate intracellular pathogen that causes sexually transmitted disease. In women, chlamydial infections may cause pelvic inflammatory disease (PID), ectopic pregnancy, and infertility. The role of antibodies in protection against a primary Chlamydia infection is unclear and was a focus of...

journal_title：Infection and immunity

authors： Shillova N,Howe SE,Hyseni B,Ridgell D,Fisher DJ,Konjufca V

更新日期：2020-12-15 00:00:00

abstract：:Streptococcus mutans, a major pathogen of dental caries, is considered one of the causative agents of infective endocarditis (IE). Recently, bacterial DNA encoding 120-kDa cell surface collagen-binding proteins (CBPs) has frequently been detected from S. mutans-positive IE patients. In addition, some of the CBP-positi...

journal_title：Infection and immunity

authors： Otsugu M,Nomura R,Matayoshi S,Teramoto N,Nakano K

更新日期：2017-11-17 00:00:00

abstract：:The protective immunity conferred by T-cell subsets against infection with Treponema pallidum subsp. pertenue was studied. We demonstrated that hamster T cells can be separated into two subsets by monoclonal antibody (MAb) GK 1.5 (anti-L3T4) and MAb 38. Eighty-five percent of hamster thymocytes were L3T4+ and 87% were...

journal_title：Infection and immunity

authors： Liu H,Alder JD,Steiner BM,Stein-Streilein J,Lim L,Schell RF

更新日期：1991-02-01 00:00:00

abstract：:l-Arginine (1 M) eluted measles virus adsorbed on monkey erythrocytes without affecting the infectious and hemagglutinating activities of the virus. This phenomenon was also observed for encephalomyocarditis virus and Newcastle disease virus. ...

journal_title：Infection and immunity

authors： Lebon P,Protat A,Moline P

更新日期：1975-06-01 00:00:00

abstract：:Chlamydial inclusions were demonstrated by indirect immunofluorescence (IF) with antiserum to the chlamydial group antigen when McCoy cell monolayers infected with either Chlamydia trachomatis or Chlamydia psittaci were fixed in formaldehyde or paraformaldehyde, provided the monolayer was not allowed to dry. If these ...

journal_title：Infection and immunity

authors： Richmond SJ,Stirling P

更新日期：1981-11-01 00:00:00