The Burkholderia cepacia epidemic strain marker is part of a novel genomic island encoding both virulence and metabolism-associated genes in Burkholderia cenocepacia.

abstract：:To characterize the mechanism by which interleukin 10 (IL-10) inhibits Th1 responses to intracellular pathogens, we evaluated the interaction between IL-10 and Mycobacterium tuberculosis-induced gamma interferon (IFN-gamma) production by peripheral blood mononuclear cells from persons across the spectrum of tuberculou...

journal_title：Infection and immunity

authors： Gong JH,Zhang M,Modlin RL,Linsley PS,Iyer D,Lin Y,Barnes PF

更新日期：1996-03-01 00:00:00

abstract：:Resequencing estA3, an allele of the methanol-soluble heat-stable enterotoxin of Escherichia coli showed that the proline triplet 19 is in fact an alanine codon; thus, estA alleles 3 and 4 were shown to be identical. Resequencing has also shown that the carboxy terminus of another allele, estA2, is not the previously ...

journal_title：Infection and immunity

authors： Guzman-Verduzco LM,Kupersztoch YM

更新日期：1989-02-01 00:00:00

abstract：:Viral hepatitis caused by infection with murine hepatitis virus strain A59 has been shown to affect the mitotic response after partial hepatectomy in mice. Normal mice showed a delayed response, whereas nude mice did not show any response, even 5 days after partial hepatectomy. ...

journal_title：Infection and immunity

authors： Carthew P

更新日期：1981-08-01 00:00:00

abstract：:In experimentally infected human volunteers, the cutaneous immune response to Haemophilus ducreyi is orchestrated by serum, polymorphonuclear leukocytes, macrophages, T cells, and myeloid dendritic cells (DC). This response either leads to spontaneous resolution of infection or progresses to pustule formation, which i...

journal_title：Infection and immunity

authors： Humphreys TL,Li L,Li X,Janowicz DM,Fortney KR,Zhao Q,Li W,McClintick J,Katz BP,Wilkes DS,Edenberg HJ,Spinola SM

更新日期：2007-12-01 00:00:00

abstract：:Infectious pancreatic necrosis virus was stable for 10 days at 4 C in stream and well water, after which the virus had a half-life of 7.5 days. At 15 C, the virus was stable for 5 days, and then had a half-life between 5 and 6 days. Viral antigen in infected cells developed much more slowly at 4 C than at 20 C. Infect...

journal_title：Infection and immunity

authors： Tu KC,Spendlove RS,Goede RW

更新日期：1975-06-01 00:00:00

abstract：:Brucella abortus injected into CBA mice replicated primarily in the spleen and liver, reaching a peak bacterial count in both organs about 7 days postinfection. The organism was eliminated from the liver but declined to a chronic phase in the spleen. The infection caused hepatosplenomegaly. An influx of macrophages in...

journal_title：Infection and immunity

authors： Doyle AG,Halliday WJ,Barnett CJ,Dunn TL,Hume DA

更新日期：1992-04-01 00:00:00

abstract：:A chemically defined medium developed for Neisseria gonorrhoeae was modified to support the growth of Campylobacter jejuni and Campylobacter coli. A total of 76 isolates of C. jejuni and 14 isolates of C. coli were tested on this medium, which was designated Campylobacter defined medium (CDM), over a 3-month period. A...

journal_title：Infection and immunity

authors： Tenover FC,Knapp JS,Patton C,Plorde JJ

更新日期：1985-05-01 00:00:00

abstract：:Formation of compact colonies of Staphylococcus aureus in serum-soft agar is mainly a result of a reaction between protein A and the Fc-part of immunoglobulin G and not a clumping factor-fibrinogen reaction. ...

journal_title：Infection and immunity

authors： Forsum U,Forsgren A,Hjelm E

更新日期：1972-10-01 00:00:00

abstract：:A common concern with many autoimmune diseases of unknown etiology is the extent to which tissue T-lymphocyte infiltrates, versus a nonspecific infiltrate, reflect a response to the causative agent. Lyme arthritis can histologically resemble rheumatoid synovitis, particularly the prominent infiltration by T lymphocyte...

journal_title：Infection and immunity

authors： Roessner K,Trivedi H,Gaur L,Howard D,Aversa J,Cooper SM,Sigal LH,Budd RC

更新日期：1998-03-01 00:00:00

abstract：:A clone expressing a 58-kDa protein reactive with human convalescent-phase serum was isolated from a recombinant library of Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis. Sequencing identified two open reading frames, one encoding a 10.3-kDa polypeptide consisting of 94 amino acids and another encod...

journal_title：Infection and immunity

authors： Sumner JW,Sims KG,Jones DC,Anderson BE

更新日期：1993-08-01 00:00:00

abstract：:We identified a T-cell determinant of the 35-kDa antigen of Mycobacterium leprae which is discriminatory against cross-sensitization by its closely related homologue in Mycobacterium avium. From synthetic peptides covering the entire sequence, those with the highest affinity and permissive binding to purified HLA-DR m...

journal_title：Infection and immunity

authors： Wilkinson RJ,Wilkinson KA,Jurcevic S,Hills A,Sinha S,Sengupta U,Lockwood DN,Katoch K,Altman D,Ivanyi J

更新日期：1999-03-01 00:00:00

abstract：:Three MudJ prototrophs demonstrated that intracellular replication is a Salmonella virulence trait (K. Y. Leung and B. B. Finlay, Proc. Natl. Acad. Sci. USA, 88:11470-11474, 1991). mutS and mutH are disrupted in mutants 3-11 and 12-23, and ssaQ is disrupted in mutant 17-21. Further analysis revealed that loss of Salmo...

journal_title：Infection and immunity

authors： Suvarnapunya AE,Zurawski DV,Guy RL,Stein MA

更新日期：2003-04-01 00:00:00

abstract：:Biomaterial-associated infections (BAI), which are predominantly caused by Staphylococcus epidermidis, are a significant problem in modern medicine. Biofilm formation is considered the pivotal element in the pathogenesis, but in previous mouse studies we retrieved S. epidermidis from peri-implant tissue. To assess the...

journal_title：Infection and immunity

authors： Broekhuizen CA,de Boer L,Schipper K,Jones CD,Quadir S,Feldman RG,Dankert J,Vandenbroucke-Grauls CM,Weening JJ,Zaat SA

更新日期：2007-03-01 00:00:00

abstract：:Mosquitoes are infected with Plasmodium falciparum by taking a blood meal from a gametocyte carrier. Since a mosquito takes a volume of 1 to 2 microl, a blood meal may contain 1 x 10(4) to 3 x 10(4) leukocytes (WBC). The majority of WBC are composed of neutrophils which may phagocytose and kill developing gametes insi...

journal_title：Infection and immunity

authors： Lensen AH,Bolmer-Van de Vegte M,van Gemert GJ,Eling WM,Sauerwein RW

更新日期：1997-09-01 00:00:00

abstract：:FMS-like tyrosine kinase-3 ligand (Flt3L) is a dendritic cell (DC) growth and differentiation factor with potential in antitumor therapies and antibacterial immunization strategies. However, the effect of systemic Flt3L treatment on lung-protective immunity against bacterial infection is incompletely defined. Here, we...

journal_title：Infection and immunity

authors： Brumshagen C,Maus R,Bischof A,Ueberberg B,Bohling J,Osterholzer JJ,Ogunniyi AD,Paton JC,Welte T,Maus UA

更新日期：2012-12-01 00:00:00

abstract：:gamma delta T cells have variously been implicated in the protection against, and the pathogenesis of, malaria, but few studies have examined the gamma delta T-cell response to malaria in African children, who suffer the large majority of malaria-associated morbidity and mortality. This is unfortunate, since available...

journal_title：Infection and immunity

authors： Hviid L,Kurtzhals JA,Adabayeri V,Loizon S,Kemp K,Goka BQ,Lim A,Mercereau-Puijalon O,Akanmori BD,Behr C

更新日期：2001-05-01 00:00:00

abstract：:A murine respiratory infection model was used to study the mechanism of protective immunity to Bordetella pertussis. We found that nude mice, which are deficient in T cells, developed a persistent infection and failed to clear the bacteria after aerosol inoculation. In contrast, normal adult nonimmune mice cleared a r...

journal_title：Infection and immunity

authors： Mills KH,Barnard A,Watkins J,Redhead K

更新日期：1993-02-01 00:00:00

abstract：:Spleen cells from BALB/c mice infected with 2 X 10(7) L. major promastigotes and developing progressive disease produced significantly lower levels of interleukin-2 (IL-2) in response to concanavalin A stimulation than did spleen cells from uninfected mice. In contrast, spleen cells from sublethally irradiated and inf...

journal_title：Infection and immunity

authors： Cillari E,Liew FY,Lelchuk R

更新日期：1986-11-01 00:00:00

abstract：:Immunoprecipitation of radiolabeled antigens with bovine antisera indicated that many Babesia bigemina and Babesia bovis merozoite proteins contain isolate-common epitopes, while at least 16 B. bigemina and 8 B. bovis proteins contain species-cross-reactive epitopes. One immunogenic, isolate-common, and species-specif...

journal_title：Infection and immunity

authors： McElwain TF,Palmer GH,Goff WL,McGuire TC

更新日期：1988-06-01 00:00:00

abstract：:Chromosomes from Cryptococcus neoformans, an encapsulated yeast pathogen, were separated by contour-clamped homogeneous field gel electrophoresis. Seven strains representing all four serotypes were studied. It was found that each strain had a unique, reproducible pattern of chromosome bands which could potentially be ...

journal_title：Infection and immunity

authors： Perfect JR,Magee BB,Magee PT

更新日期：1989-09-01 00:00:00

abstract：:Intracellular survival of Chlamydia psittaci is in part dependent on the ability of the organism to thwart phagolysosome formation. Circumvention of phagolysosome fusion could be either localized to chlamydia-laden vacuoles or generalized to all phagosomes in the host cell. To determine which of these modes is in oper...

journal_title：Infection and immunity

authors： Eissenberg LG,Wyrick PB

更新日期：1981-05-01 00:00:00

abstract：:We report here on the isolation of isogenic strains of Aeromonas hydrophila AB3 deleted for a segment of the aerolysin gene. All aer mutants obtained lacked the 49-kilodalton aerolysin gene product and were neither hemolytic for blood erythrocytes nor cytotoxic for Chinese hamster ovary tissue culture cells. One such ...

journal_title：Infection and immunity

authors： Chakraborty T,Huhle B,Hof H,Bergbauer H,Goebel W

更新日期：1987-09-01 00:00:00

abstract：:A ruthenium red-staining capsule was observed on two pathogenic strains, but not on one nonpathogenic strain of Mycoplasma gallisepticum. The capsule appeared to mediate cytadsorption of mycoplasmas to the chicken tracheal epithelium without evidence of membrane fusion. No relationship was seen between the presence of...

journal_title：Infection and immunity

authors： Tajima M,Yagihashi T,Miki Y

更新日期：1982-05-01 00:00:00

abstract：:Staphylococcus aureus is an important opportunistic pathogen and is the etiological agent of many hospital- and community-acquired infections. The golden pigment, staphyloxanthin, of S. aureus colonies distinguishes it from other staphylococci and related Gram-positive cocci. Staphyloxanthin is the product of a series...

journal_title：Infection and immunity

authors： Hall JW,Yang J,Guo H,Ji Y

更新日期：2017-01-26 00:00:00

abstract：:A gene from Haemophilus influenzae encoding an outer membrane lipoprotein of about 15,000 daltons and which comigrates with the peptidoglycan-associated lipoprotein (PAL) of H. influenzae on sodium dodecyl sulfate-polyacrylamide gel electrophoresis has been previously reported and designated pcp gene, and its product ...

journal_title：Infection and immunity

authors： Deich RA,Anilionis A,Fulginiti J,Metcalf BJ,Quataert S,Quinn-Dey T,Zlotnick GW,Green BA

更新日期：1990-10-01 00:00:00

abstract：:The antiinflammatory cytokine response during urosepsis was determined by measurement of concentrations of soluble tumor necrosis factor receptor (sTNFR) types I and II, interleukin 1 receptor antagonist (IL-1ra), soluble IL-1 receptor type II (sIL-1RII), and interleukin 10 in sera and urine of 30 patients with cultur...

journal_title：Infection and immunity

authors： Olszyna DP,Prins JM,Buis B,van Deventer SJ,Speelman P,van der Poll T

更新日期：1998-08-01 00:00:00

abstract：:Amebic erythrophagocytosis is characteristic of invasive amebiasis, and mutants deficient in erythrocyte ingestion are avirulent. We sought to understand the molecular mechanisms underlying erythrocyte phagocytosis by Entamoeba histolytica. Following adherence to amebae, erythrocytes became round and crenulated, and p...

journal_title：Infection and immunity

authors： Boettner DR,Huston CD,Sullivan JA,Petri WA Jr

更新日期：2005-06-01 00:00:00

abstract：:A main feature in the pathogenesis of bacterial endocarditis is the activation of the coagulation system via the extrinsic pathway, resulting in the formation of infected endocardial vegetations. Earlier studies gave indirect evidence that monocytes play an important role in the procoagulant response during the course...

journal_title：Infection and immunity

authors： Bancsi MJ,Veltrop MH,Bertina RM,Thompson J

更新日期：1996-02-01 00:00:00

abstract：:The protein P2 comprises a large proportion of the outer membrane of nontypable Haemophilus influenzae and functions as a porin. In view of the importance of the protein as a surface antigen, the present study was designed to purify and analyze P2 with particular emphasis on detection of antigenic determinants express...

journal_title：Infection and immunity

authors： Murphy TF,Bartos LC

更新日期：1988-05-01 00:00:00

abstract：:Slime production is not a generally recognized feature of Staphylococcus epidermidis. In a recent outbreak of S. epidermidis intravascular catheter-associated sepsis, we noted that 63% of clinically implicated strains grew as a slimy film coating the culture tube walls when propagated in tryptic soy broth. Only 37% of...

journal_title：Infection and immunity

authors： Christensen GD,Simpson WA,Bisno AL,Beachey EH

更新日期：1982-07-01 00:00:00