Leukocytes in a Plasmodium falciparum-infected blood meal reduce transmission of malaria to Anopheles mosquitoes.

abstract：:Changes in cell viability and in factors affecting metabolic integrity were examined after exposure of Escherichia coli LP1092 to human serum. Antibody-dependent classical pathway activity accounted for the rapid killing of strain LP1092 by complement. Removal of serum lysozyme by bentonite absorption or by neutraliza...

journal_title：Infection and immunity

authors： Taylor PW,Kroll HP

更新日期：1983-01-01 00:00:00

abstract：:Despite effective antimicrobial chemotherapy, control of Chlamydia trachomatis urogenital infection will likely require a vaccine. We have assessed the protective effect of an outer membrane protein-based vaccine by using a murine model of chlamydial genital infection. Female mice were first vaccinated with Chlamydia ...

journal_title：Infection and immunity

authors： Farris CM,Morrison SG,Morrison RP

更新日期：2010-10-01 00:00:00

abstract：:The route of pathogen inoculation by needle has been shown to influence the outcome of infection. Employing needle inoculation of the obligately intracellular parasite Leishmania major, which is transmitted in nature following intradermal (i.d.) deposition of parasites by the bite of an infected sand fly, we identifie...

journal_title：Infection and immunity

authors： Ribeiro-Gomes FL,Roma EH,Carneiro MB,Doria NA,Sacks DL,Peters NC

更新日期：2014-07-01 00:00:00

abstract：:Woodchuck sera were tested for antigens and antibodies with tests which detect human hepatitis virus antigens and antibodies. Data on 264 woodchuck sera are presented. ...

journal_title：Infection and immunity

authors： Millman I,Halbherr T,Simmons H

更新日期：1982-02-01 00:00:00

abstract：:Performing patch-clamp experiments on human macrophages, we show that the K(+) channel MaxiK is activated by lipopolysaccharide, peptidoglycan, and interleukin-1. Cytokine production initiated by several Toll-like receptor (TLR) ligands and by interleukin-1 is inhibited by MaxiK blockade. This provides evidence for fu...

journal_title：Infection and immunity

authors： Scheel O,Papavlassopoulos M,Blunck R,Gebert A,Hartung T,Zähringer U,Seydel U,Schromm AB

更新日期：2006-07-01 00:00:00

abstract：:Curli are thin, coiled fibers expressed on the surface of Escherichia coli that bind several matrix and plasma proteins such as fibronectin, laminin, plasminogen, tissue plasminogen activator, and H-kininogen. In this work, we examined the interactions between curli-expressing E. coli and human major histocompatibilit...

journal_title：Infection and immunity

authors： Olsén A,Wick MJ,Mörgelin M,Björck L

更新日期：1998-03-01 00:00:00

abstract：:Invasive aspergillosis is a serious fungal infection caused by the proliferation and invasion of Aspergillus hyphae in tissue. Neutrophils (PMNs) are the most important line of defense against Aspergillus hyphae. To investigate the role of granulocyte colony-stimulating factor (G-CSF) and gamma interferon (IFN-gamma) ...

journal_title：Infection and immunity

authors： Roilides E,Uhlig K,Venzon D,Pizzo PA,Walsh TJ

更新日期：1993-04-01 00:00:00

abstract：:The triggering receptor expressed on myeloid cell type 1 (TREM-1) is a cell surface molecule that has been identified on both human and murine polymorphonuclear neutrophils and mature monocytes. The activation of TREM-1 in the presence of microbial components amplifies the inflammatory response and may be responsible ...

journal_title：Infection and immunity

authors： Gibot S,Buonsanti C,Massin F,Romano M,Kolopp-Sarda MN,Benigni F,Faure GC,Béné MC,Panina-Bordignon P,Passini N,Lévy B

更新日期：2006-05-01 00:00:00

abstract：:Several strains of gram-negative bacteria (seven genera, eight species) isolated from patients with urinary tract infections were found to hydrolyze myeloma immunoglobulin A (IgA) protein. Human IgG and IgM and colostrum IgA were not degraded by these organisms. Examination of cleavage digests showed two fragments of ...

journal_title：Infection and immunity

authors： Milazzo FH,Delisle GJ

更新日期：1984-01-01 00:00:00

abstract：:Although protective immunity in C57BL/6 mice induced by a single dose of the radiation-attenuated schistosome vaccine is believed to be mediated by Th1-type immune responses, we here report that in BALB/c mice protection can also depend upon signaling via the interleukin-4 (IL-4) receptor which conventionally governs ...

journal_title：Infection and immunity

authors： Mountford AP,Hogg KG,Coulson PS,Brombacher F

更新日期：2001-01-01 00:00:00

abstract：:We evaluated sexual recombination in the apicomplexan parasite Theileria parva using genome-wide marker analysis of haploid sporozoite populations obtained from infected Rhipicephalus appendiculatus ticks. Analysis of 231 parasite clones derived by in vitro infection of bovine lymphocytes revealed 48 distinct combinat...

journal_title：Infection and immunity

authors： Katzer F,Ngugi D,Oura C,Bishop RP,Taracha EL,Walker AR,McKeever DJ

更新日期：2006-10-01 00:00:00

abstract：:Escherichia coli is a major cause of enteric/diarrheal diseases, urinary tract infections, and sepsis. E. coli K1 is the leading gram-negative organism causing neonatal meningitis, but the microbial basis of E. coli K1 meningitis is incompletely understood. Here we employed comparative genomic hybridization to investi...

journal_title：Infection and immunity

authors： Yao Y,Xie Y,Kim KS

更新日期：2006-04-01 00:00:00

abstract：:Intrauterine infections lead to serious complications for mother and fetus, including preterm birth, maternal and fetal death, and neurological sequelae in the surviving offspring. Improving maternal and child heath is a global priority. Yet, the development of strategies to prevent and treat pregnancy-related disease...

journal_title：Infection and immunity

authors： Lowe DE,Robbins JR,Bakardjiev AI

更新日期：2018-05-22 00:00:00

abstract：:This study was undertaken to determine the sequence of events in the microenvironment of the intestinal tract that culminate in the symptoms of cholera and to attempt to define more clearly the mechanisms involved in antibacterial immunity. The extent to which mucus occurs in the normal intestine of rabbits and the ap...

journal_title：Infection and immunity

authors： Schrank GD,Verwey WF

更新日期：1976-01-01 00:00:00

abstract：:Molecular approaches to the rapid analysis of the serotyping antigens of Neisseria meningitidis, the class 2 and 3 outer membrane proteins (OMPs), were developed, evaluated, and used to study 12 antigenic variants of these proteins. A primer set for the polymerase chain reaction (PCR) amplification of the genes encodi...

journal_title：Infection and immunity

authors： Feavers IM,Suker J,McKenna AJ,Heath AB,Maiden MC

更新日期：1992-09-01 00:00:00

abstract：:The objective of these studies was to determine the role of macrophage inflammatory protein 1alpha/CCL3 in pulmonary host defense during Klebsiella pneumoniae infection. Following intratracheal inoculation, 7-day survival of CCL3(-/-) mice was less than 10%, compared to 60% for CCL3(+/+) mice. Survival of CCR5(-/-) mi...

journal_title：Infection and immunity

authors： Lindell DM,Standiford TJ,Mancuso P,Leshen ZJ,Huffnagle GB

更新日期：2001-10-01 00:00:00

abstract：:The antigenic relationship of six different strains of Paracoccidioides brasiliensis was investigated by the agar-gel immunodiffusion test. Soluble antigens prepared from the two morphological phases of the fungus were diffused against human sera obtained from eight patients with paracoccidioidomycosis (South American...

journal_title：Infection and immunity

authors： Restrepo-Moreno A

更新日期：1970-09-01 00:00:00

abstract：:We have developed a novel ileal loop model for use in calves to analyze the contribution of Salmonella enterica serovar Typhimurium type III secretion systems to disease processes in vivo. Our model involves constructing ileal loops with end-to-end anastamoses to restore the patency of the small intestine, thereby all...

journal_title：Infection and immunity

authors： Coombes BK,Coburn BA,Potter AA,Gomis S,Mirakhur K,Li Y,Finlay BB

更新日期：2005-11-01 00:00:00

abstract：:We have shown that a member of the 70-kDa heat shock protein (Hsp70) family is a major target of the humoral immune response during Leishmania donovani infection. A recombinant fusion protein was recognized by sera from 92% (35 of 38) of patients with visceral leishmaniasis, including representatives from each of the ...

journal_title：Infection and immunity

authors： Wallace GR,Ball AE,MacFarlane J,el Safi SH,Miles MA,Kelly JM

更新日期：1992-07-01 00:00:00

abstract：:Conditions are described for the production of an extracellular cytotoxin or CHO cell-killing factor by Vibrio fluvialis, a recently recognized enteric pathogen. The cell-killing factor was ammonium sulfate precipitable, heat labile, and inactivated by proteases, and had an isoelectric point (estimated by sucrose dens...

journal_title：Infection and immunity

authors： Wall VW,Kreger AS,Richardson SH

更新日期：1984-12-01 00:00:00

abstract：:Interleukin-10 (IL-10) is associated with inhibition of cell-mediated immunity and downregulation of the expression of costimulatory molecules required for T-cell activation. When IL-10-deficient (IL-10KO) mice are infected with Toxoplasma gondii, they succumb to a T-cell-mediated shock-like reaction characterized by ...

journal_title：Infection and immunity

authors： Villegas EN,Wille U,Craig L,Linsley PS,Rennick DM,Peach R,Hunter CA

更新日期：2000-05-01 00:00:00

abstract：:PspA is an antigenically variable surface protein of Streptococcus pneumoniae that appears to be essential for full pneumococcal virulence. In addition, monoclonal antibodies to PspA protect mice against infection with specific strains of pneumococci virulent for mice. In this study, we have isolated the 43-kDa N-term...

journal_title：Infection and immunity

authors： Talkington DF,Crimmins DL,Voellinger DC,Yother J,Briles DE

更新日期：1991-04-01 00:00:00

abstract：:Vibrio parahaemolyticus, an important agent of seafood-borne gastroenteritis, expresses several putative virulence factors that could account for the disease symptoms of infected humans, namely, diarrhea, nausea, and abdominal cramps. The pathogenicity of V. parahaemolyticus correlates well with the Kanagawa phenomeno...

journal_title：Infection and immunity

authors： Huntley JS,Hall AC,Sathyamoorthy V,Hall RH

更新日期：1993-10-01 00:00:00

abstract：:Gram-negative bacterial pathogens utilize virulence-associated secretion systems to inject, or translocate, effector proteins into host cells to manipulate cellular processes and promote bacterial replication. However, translocated bacterial products are sensed by nucleotide binding domain and leucine-rich repeat-cont...

journal_title：Infection and immunity

authors： Zwack EE,Feeley EM,Burton AR,Hu B,Yamamoto M,Kanneganti TD,Bliska JB,Coers J,Brodsky IE

更新日期：2017-09-20 00:00:00

abstract：:A comparison of viral-induced unresponsiveness of phytohemagglutinin (PHA)-induced deoxyribonucleic acid (DNA) synthesis of mouse lymphocytes was made by culturing the cells under identical conditions in the presence of HEPES buffer in a humid-air atmosphere. The degree of PHA-induced DNA synthesis was found to vary, ...

journal_title：Infection and immunity

authors： Rogers HJ

更新日期：1973-03-01 00:00:00

abstract：:Mice pretreated intraperitoneally with trehalose-6,6'-dimycolate (cord factor) were protected against an intraperitoneal challenge with Salmonella typhi strain Ty2 or Salmonella typhimurium strain SR 11. The nonspecific resistance to S. typhi and S. typhimurium was still detectable 7 and 14 days, respectively, after a...

journal_title：Infection and immunity

authors： Yarkoni E,Bekierkunst A

更新日期：1976-11-01 00:00:00

abstract：:Gastroesophageal reflux (GER) frequently occurs in patients with respiratory disease and is particularly prevalent in patients with cystic fibrosis. GER is a condition in which the duodenogastric contents of the stomach leak into the esophagus, in many cases resulting in aspiration into the respiratory tract. As such,...

journal_title：Infection and immunity

authors： Legendre C,Reen FJ,Woods DF,Mooij MJ,Adams C,O'Gara F

更新日期：2014-09-01 00:00:00

abstract：:An immunogenic aminopeptidase was purified from Brucella melitensis strain VTRM1. The purification procedure consisted of ammonium sulfate fractionation and three chromatographic steps. This procedure resulted in a yield of 29% and a 144-fold increase in specific activity. The aminopeptidase appeared to be a monomeric...

journal_title：Infection and immunity

authors： Contreras-Rodriguez A,Ramirez-Zavala B,Contreras A,Schurig GG,Sriranganathan N,Lopez-Merino A

更新日期：2003-09-01 00:00:00

abstract：:Toll-like receptor (TLR)-based signaling pathways in the host may be modulated by pathogens during the course of infection. We describe a novel immunomodulatory mechanism in which Aspergillus fumigatus conidia induce attenuation of TLR2- and TLR4-mediated interleukin (IL)-6 and IL-1beta proinflammatory responses in hu...

journal_title：Infection and immunity

authors： Chai LY,Kullberg BJ,Vonk AG,Warris A,Cambi A,Latgé JP,Joosten LA,van der Meer JW,Netea MG

更新日期：2009-05-01 00:00:00

abstract：:The method of Garra and Baygorria, for localized antibody production, has been adapted for obtaining high-titered and monospecific antibodies against the murine toxin of Yersinia pestis. A hollow, perforated plastic golf ball surgically implanted under the skin of rabbits induced the formation of a granuloma. When the...

journal_title：Infection and immunity

authors： Hillam RP,Tengerdy RP,Brown GL

更新日期：1974-09-01 00:00:00