Abortion in laboratory animals induced by Moraxella bovis.

Abstract:

:Pregnant mice, guinea pigs, rats, and rabbits responded to injections of Moraxella bovis strain EPP-63(300) with abortion, death, embryo resorption, and production of small litters. The nature of response appeared to depend primarily on the number of viable cells injected and to some extent on the species of animal and stage of pregnancy. Intraperitoneal injection of mice with 3 X 10(5) viable cells induced 100% abortion and no deaths. Embryo resorption and smaller litters were induced with injection of lower doses of M. bovis. None of the rats used in this study aborted; however, resorption rates were higher in rats than mice. Bacteria-free filtrates prepared from aqueous extracts of blood agar on which M. bovis had been grown induced abortion in mice and guinea pigs, at a rate similar to that caused by viable cells. The lyophilized filtrate could be diluted to produce 100% abortion with no death of injected mice. Abortion-inducing, nonlethal doses of M. bovis and lyophilized filtrates appeared to have no effect on nonpregnant female or male mice.

journal_name

Infect Immun

journal_title

Infection and immunity

authors

Norman JO,Elissalde MH

doi

10.1128/IAI.24.2.427-433.1979

subject

Has Abstract

pub_date

1979-05-01 00:00:00

pages

427-33

issue

2

eissn

0019-9567

issn

1098-5522

journal_volume

24

pub_type

杂志文章
  • M proteins of group G streptococci isolated from bacteremic human infections.

    abstract::We studied seven strains of group G streptococci isolated from clinically severe bacteremic infections in six intravenous drug abusers. These group G strains multiplied luxuriantly in fresh human blood. On electron microscopy, they exhibited surface fibrillae similar to those observed in M-protein-rich group A strepto...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.55.3.753-757.1987

    authors: Bisno AL,Craven DE,McCabe WR

    更新日期:1987-03-01 00:00:00

  • Experimental hematogenous candidiasis caused by Candida krusei and Candida albicans: species differences in pathogenicity.

    abstract::Hematogenous infections caused by Candida krusei have been noted with increasing frequency, particularly in cancer patients receiving prophylaxis with antifungal triazoles. Progress in understanding the pathogenesis of this emerging infection has been limited by the lack of an animal model. We developed a CF1 mouse in...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.61.4.1268-1271.1993

    authors: Anaissie E,Hachem R,K-Tin-U C,Stephens LC,Bodey GP

    更新日期:1993-04-01 00:00:00

  • Role of a cell surface-associated protein in adherence and dental caries.

    abstract::Insertional inactivation of the Streptococcus mutans spaP gene was used to construct an isogenic mutant (834) of strain NG8 (serotype c) which lacked the major cell surface-associated protein referred to as P1 (15). Results of several studies suggest that P1 is involved in the adherence of S. mutans to saliva-coated a...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.59.12.4606-4609.1991

    authors: Bowen WH,Schilling K,Giertsen E,Pearson S,Lee SF,Bleiweis A,Beeman D

    更新日期:1991-12-01 00:00:00

  • Complement-independent binding of microorganisms to primate erythrocytes in vitro by cross-linked monoclonal antibodies via complement receptor 1.

    abstract::Under certain circumstances, soluble antigens, particulate antigens, and/or microorganisms have been shown to bind to primate erythrocytes via complement receptor 1 (CR1) in the presence of specific antibodies and complement. This immune adherence reaction, specific for CR1, can lead to neutralization of antigens in t...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.63.4.1329-1335.1995

    authors: Powers JH,Buster BL,Reist CJ,Martin E,Bridges M,Sutherland WM,Taylor RP,Scheld WM

    更新日期:1995-04-01 00:00:00

  • Localization of translocating Escherichia coli, Proteus mirabilis, and Enterococcus faecalis within cecal and colonic tissues of monoassociated mice.

    abstract::Normal bacteria can translocate (migrate) across an intact intestinal mucosa, but the anatomical site of bacterial translocation has not been defined. Gastrointestinal (GI) cross-sections were obtained from mice monoassociated with high cecal concentrations of Escherichia coli, Proteus mirabilis, or Enterococcus faeca...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.59.12.4693-4697.1991

    authors: Wells CL,Erlandsen SL

    更新日期:1991-12-01 00:00:00

  • Properties of crude Campylobacter jejuni heat-labile enterotoxin.

    abstract::The amount of crude Campylobacter jejuni enterotoxin present in culture products was quantitated by comparing the response of these preparations with that of pure Escherichia coli heat-labile toxin (LT) in the Chinese hamster ovary assay and in enzyme-linked immunosorbent assays that used GM ganglioside or antisera to...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.45.2.314-319.1984

    authors: Klipstein FA,Engert RF

    更新日期:1984-08-01 00:00:00

  • Experimental infection in mice with Treponema hyodysenteriae.

    abstract::Nineteen of 22 female mice (CF1 strain) inoculated intragastrically with Treponema hyodysenteriae developed cecal and colonic lesions consisting of catarrhal inflammation, edema, and occasional hemorrhage. ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.25.2.757-760.1979

    authors: Joens LA,Glock RD

    更新日期:1979-08-01 00:00:00

  • Serum immune response to Shigella protein antigens in rhesus monkeys and humans infected with Shigella spp.

    abstract::The serum antibody response to proteins encoded by the virulence-associated plasmid of Shigella flexneri was determined in monkeys challenged with virulent S. flexneri serotype 2a. With water-extractable antigen in an enzyme-linked immunosorbent assay, a significant increase in antibody titer against proteins from a p...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.53.1.57-63.1986

    authors: Oaks EV,Hale TL,Formal SB

    更新日期:1986-07-01 00:00:00

  • Ultrastructural observations on cellular and subcellular aspects of experimental Mycoplasma pneumoniae disease.

    abstract::The ultrastructural organization of Mycoplasma pneumoniae membranes and spatial relationships of this pathogen to epithelial cells in tracheal organ cultures were examined ultrastructurally by freeze-fracture techniques. Areas of morphologically distinct cell membrane variability characterized by membrane blebs and al...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:

    authors: Carson JL,Collier AM,Hu SC

    更新日期:1980-09-01 00:00:00

  • Impact of mosquito bites on asexual parasite density and gametocyte prevalence in asymptomatic chronic Plasmodium falciparum infections and correlation with IgE and IgG titers.

    abstract::An immunomodulatory role of arthropod saliva has been well documented, but evidence for an effect on Plasmodium sp. infectiousness remains controversial. Mosquito saliva may orient the immune response toward a Th2 profile, thereby priming a Th2 response against subsequent antigens, including Plasmodium. Orientation to...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.06414-11

    authors: Lawaly R,Konate L,Marrama L,Dia I,Diallo D,Diène Sarr F,Schneider BS,Casademont I,Diallo M,Brey PT,Sakuntabhai A,Mecheri S,Paul R

    更新日期:2012-06-01 00:00:00

  • Bivalency is required for anticapsular monoclonal antibodies to optimally suppress activation of the alternative complement pathway by the Cryptococcus neoformans capsule.

    abstract::Encapsulated cells of Cryptococcus neoformans are potent activators of the alternative complement pathway. Previous studies found that monoclonal antibodies (MAbs) specific for the major capsular polysaccharide, termed glucuronoxylomannan (GXM), can markedly suppress the ability of the capsule to accumulate C3 from no...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.66.4.1547-1553.1998

    authors: Kozel TR,MacGill RS,Wall KK

    更新日期:1998-04-01 00:00:00

  • Adhesion of enterotoxigenic Escherichia coli to human small intestinal enterocytes.

    abstract::An improved enterocyte adhesion assay has been used to examine a collection of 44 strains of enterotoxigenic Escherichia coli (ETEC) for their ability to adhere to the brush border of isolated human duodenal enterocytes. Fourteen strains showed good adhesion; in each case the ability to adhere correlated with the prod...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.48.3.824-831.1985

    authors: Knutton S,Lloyd DR,Candy DC,McNeish AS

    更新日期:1985-06-01 00:00:00

  • Local passive immunization by monoclonal antibodies against streptococcal antigen I/II in the prevention of dental caries.

    abstract::Local passive immunization with monoclonal antibodies (Mc Ab) to Streptococcus mutans was attempted as an alternative approach to active systemic immunization. We prepared an immunoglobulin G class Mc Ab to the cell surface protein determinant of streptococcal antigen I/II and applied it repeatedly to the teeth of rhe...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.50.3.796-799.1985

    authors: Lehner T,Caldwell J,Smith R

    更新日期:1985-12-01 00:00:00

  • Biochemical and immunological characterization of deoxythymidine kinase of thymidine kinaseless HeLa cells biochemically transformed by herpes simplex virus type.

    abstract::Thymidine kinase (TK) from herpes simplex virus type 1 (HSV-1) biochemically transformed HeLa cells, purified by affinity chromatography, has been characterized with respect to its electrophoretic mobility, molecular weight, activation energy, substrate specificity, and immunological specificity. TK purified from HSV-...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.16.2.486-492.1977

    authors: Cheng YC,Chadha KC,Hughes RG Jr

    更新日期:1977-05-01 00:00:00

  • HYP1, a hydrophobin gene from Aspergillus fumigatus, complements the rodletless phenotype in Aspergillus nidulans.

    abstract::Aspergillus fumigatus produces conidia that are highly dispersable and resistant to degradation. We have sought to analyze these properties by studying the rodlets which form the outer spore coat protein. Degenerate primers based on hydrophobins in other fungi were applied to genomic DNA from A. fumigatus in PCR. A pr...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.62.10.4389-4395.1994

    authors: Parta M,Chang Y,Rulong S,Pinto-DaSilva P,Kwon-Chung KJ

    更新日期:1994-10-01 00:00:00

  • Function of various intestinal bacteria in converting germfree mice to the normal state.

    abstract::Earlier work had shown that a collection of anaerobic bacteria, in conjunction with facultative anaerobes, may be implanted into germfree mice, thereby rendering the animals "normal" with respect to a variety of parameters tested. The present experiments indicate that a different collection of anaerobic bacteria, isol...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.6.2.119-126.1972

    authors: Freter R,Abrams GD

    更新日期:1972-08-01 00:00:00

  • Bordetella pertussis infection of primary human monocytes alters HLA-DR expression.

    abstract::Bordetella pertussis is the causative agent of whooping cough, a potentially lethal respiratory disease in children. In immunocompetent individuals, B. pertussis infection elicits an effective adaptive immune response driven by activated CD4(+) T cells. However, live B. pertussis persists in the host for 3 to 4 weeks ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/iai.72.3.1450-1462.2004

    authors: Shumilla JA,Lacaille V,Hornell TM,Huang J,Narasimhan S,Relman DA,Mellins ED

    更新日期:2004-03-01 00:00:00

  • Effect of gamma interferon on phospholipid hydrolysis and fatty acid incorporation in L929 cells infected with Rickettsia prowazekii.

    abstract::Treatment of Rickettsia prowazekii-infected L929 cells with gamma interferon (IFN-gamma) immediately after infection altered the lipid metabolism of the host cells as determined by measurement of phospholipid hydrolysis and oleic acid incorporation into phospholipids and neutral lipids. At 48 h postinfection, there wa...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.61.8.3412-3415.1993

    authors: Winkler HH,Day L,Daugherty R,Turco J

    更新日期:1993-08-01 00:00:00

  • Growth within macrophages increases the efficiency of Mycobacterium avium in invading other macrophages by a complement receptor-independent pathway.

    abstract::Infections caused by organisms of the Mycobacterium avium complex occur in approximately 50 to 60% of patients with AIDS. M. avium is an intracellular pathogen that survives and multiplies within mononuclear phagocytes. In this study, we investigated the uptake of M. avium grown within macrophages (intracellular growt...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.65.5.1916-1925.1997

    authors: Bermudez LE,Parker A,Goodman JR

    更新日期:1997-05-01 00:00:00

  • Microbial amyloids induce interleukin 17A (IL-17A) and IL-22 responses via Toll-like receptor 2 activation in the intestinal mucosa.

    abstract::The Toll-like receptor 2 (TLR2)/TLR1 receptor complex responds to amyloid fibrils, a common component of biofilm material produced by members of the phyla Firmicutes, Bacteroidetes, and Proteobacteria. To determine whether this TLR2/TLR1 ligand stimulates inflammatory responses when bacteria enter intestinal tissue, w...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00911-12

    authors: Nishimori JH,Newman TN,Oppong GO,Rapsinski GJ,Yen JH,Biesecker SG,Wilson RP,Butler BP,Winter MG,Tsolis RM,Ganea D,Tükel Ç

    更新日期:2012-12-01 00:00:00

  • Restriction of Toxoplasma gondii growth in human brain microvascular endothelial cells by activation of indoleamine 2,3-dioxygenase.

    abstract::One of the first steps in the development of cerebral toxoplasmosis is the penetration of the blood-brain barrier, which is comprised of microvascular endothelial cells. We examined the capacity of human brain microvascular endothelial cells (HBMEC) to interact with Toxoplasma gondii. We found that stimulation of HBME...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.69.10.6527-6531.2001

    authors: Däubener W,Spors B,Hucke C,Adam R,Stins M,Kim KS,Schroten H

    更新日期:2001-10-01 00:00:00

  • Use of an alkali-soluble water-soluble extract of Blastomyces dermatitidis yeast-phase cell walls and isoelectrically focused components in peripheral lymphocyte transformations.

    abstract::An alkali-soluble water-soluble extract of Blastomyces dermatitidis yeast-phase cell walls was tested for its ability to elicit a response in lymphocytes isolated from the peripheral blood of Blastomyces-infected guinea pigs. Sequential preparations of the antigen were reproducible and specific in the in vitro lymphoc...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.19.2.411-415.1978

    authors: Hall NK,Deighton F,Larsh HW

    更新日期:1978-02-01 00:00:00

  • Inability of pyrogenic, purified Bordetella pertussis lipid A to induce interleukin-1 release by human monocytes.

    abstract::Free lipid A of Bordetella pertussis, Neisseria meningitidis, and Escherichia coli lipopolysaccharide (LPS) was prepared by hydrolysis in acetate buffer (pH 4.5); in addition, lipid A from B. pertussis and E. coli was prepared by hydrolysis in mineral acid (HCl). The precipitates obtained were purified by extraction m...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.54.2.465-471.1986

    authors: Caroff M,Cavaillon JM,Fitting C,Haeffner-Cavaillon N

    更新日期:1986-11-01 00:00:00

  • Capsule reduces adherence of enterotoxigenic Escherichia coli to isolated intestinal epithelial cells of pigs.

    abstract::Previous reports have demonstrated that heat-stable (A-type) capsule on piliated enterotoxigenic Escherichia coli enhances colonization of enterotoxigenic E. coli in the small intestine and enhances virulence of enterotoxigenic E. coli. In this report, four encapsulated enterotoxigenic E. coli strains and one encapsul...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.45.3.737-740.1984

    authors: Runnels PL,Moon HW

    更新日期:1984-09-01 00:00:00

  • Immunochemistry of the streptococcal group R cell wall polysaccharide antigen.

    abstract::The group R streptococcal group antigen has been shown to be a polysaccharide located at the surface of the cell wall of the organism. The antigen was extracted from cell walls in 0.05 n HCl or 5% trichloracetic acid at 100 C, from whole cells at room temperature in 0.85% NaCl or 0.1 m acetate (pH 5.0), and by sonic o...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.5.1.91-97.1972

    authors: Soprey P,Slade HD

    更新日期:1972-01-01 00:00:00

  • Contribution of clumping factor B to pathogenesis of experimental endocarditis due to Staphylococcus aureus.

    abstract::Staphylococcus aureus Newman with an insertion mutation in clfB, the gene encoding clumping factor B, only marginally decreased infection rate (P>0.05) in rats with experimental endocarditis. In contrast, clfB complementation on a multicopy plasmid significantly increased infectivity (P<0.05) over the deleted mutants....

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/iai.68.9.5443-5446.2000

    authors: Entenza JM,Foster TJ,Ni Eidhin D,Vaudaux P,Francioli P,Moreillon P

    更新日期:2000-09-01 00:00:00

  • Identification of lipoprotein homologues of pneumococcal PsaA in the equine pathogens Streptococcus equi and Streptococcus zooepidemicus.

    abstract::Streptococcus equi and Streptococcus zooepidemicus are major etiological agents of upper and lower airway disease in horses. Despite the considerable animal suffering and economic burden associated with these diseases, the factors that contribute to the virulence of these equine pathogens have not been extensively inv...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/iai.68.10.6048-6051.2000

    authors: Harrington DJ,Greated JS,Chanter N,Sutcliffe IC

    更新日期:2000-10-01 00:00:00

  • Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin.

    abstract::Conjugated polysaccharide vaccines protect against serogroup C meningococci. However, this approach cannot be applied to serogroup B, which is still a major cause of meningitis. We evaluated the immunogenicity of three surface-exposed proteins from serogroup B Neisseria meningitidis (App, NhhA, and NadA) identified du...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.72.7.4052-4060.2004

    authors: Bowe F,Lavelle EC,McNeela EA,Hale C,Clare S,Arico B,Giuliani MM,Rae A,Huett A,Rappuoli R,Dougan G,Mills KH

    更新日期:2004-07-01 00:00:00

  • Production of cholera toxin-like toxin by Vibrio mimicus and non-O1 Vibrio cholerae: batch culture conditions for optimum yields and isolation of hypertoxigenic lincomycin-resistant mutants.

    abstract::Vibrio mimicus 61892, isolated in 1977 from a case of watery diarrhea in Bangladesh, produces an enterotoxin which possesses activity in Y-1 mouse adrenal cells and in rabbit ileal loops which is identical to the prototype cholera toxin (CT) produced by Vibrio cholerae 569B. The neutralization of the adrenal cell acti...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.42.2.501-509.1983

    authors: Spira WM,Fedorka-Cray PJ

    更新日期:1983-11-01 00:00:00

  • T lymphocyte subpopulations in congenital cytomegalovirus infection.

    abstract::T lymphocyte subpopulations in the peripheral blood of children with congenital cytomegalovirus infections and in controls were enumerated with monoclonal antibodies. Infants of less than 1 year of age with symptomatic infections showed significant increases in the proportion of suppressor cells and decreases in the r...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.41.3.1380-1382.1983

    authors: Pass RF,Roper MA,August AM

    更新日期:1983-09-01 00:00:00