Immunochemistry of the streptococcal group R cell wall polysaccharide antigen.

abstract：:We undertook a morphological and immunochemical comparison of purified outer membrane antigens from oral and nonoral isolates of Bacteroides asaccharolyticus. Electron micrographs of thin sections of whole bacteria revealed a compact, electron-dense capsule external to the outer membrane of oral strains. A loose, web-...

journal_title：Infection and immunity

authors： Mansheim BJ,Coleman SE

更新日期：1980-02-01 00:00:00

abstract：:Yersinia pestis causes bubonic, pneumonic, and septicemic plague, diseases that are rapidly lethal to most mammals, including humans. Plague develops as a consequence of bacterial neutralization of the host's innate immune response, which permits uncontrolled growth and causes the systemic hyperactivation of the infla...

journal_title：Infection and immunity

authors： Dhariwala MO,Olson RM,Anderson DM

更新日期：2017-10-18 00:00:00

abstract：:The immunopathology of Chagas' disease was studied in the experimental model of chronic infection in C57BL/10JT or mice. Sublethal infection with Trypanosoma cruzi, Y strain, induced specific antibodies and a delayed hypersensitivity response to parasite antigens. Mice developed chronic chagasic myocarditis but not sk...

journal_title：Infection and immunity

authors： Mortatti RC,Maia LC,de Oliveira AV,Munk ME

更新日期：1990-11-01 00:00:00

abstract：:A group of insertion mutants was used to define the genes of plasmid pDC5 required for the expression of mannose-resistant fimbriae. Minicell experiments identified four polypeptides (71,000, 45,000, 27,000, and 17,000 daltons) concerned with fimbrial production, the smallest of these being the fimbrial subunit. The a...

journal_title：Infection and immunity

authors： Clegg S,Pierce JK

更新日期：1983-12-01 00:00:00

abstract：:Cell-free hemoglobin (Hb) is being developed as an erythrocyte substitute. We have previously demonstrated that cell-free Hb is an endotoxin-binding protein which disaggregates endotoxin and subsequently increases the biological activity of endotoxin in several in vitro assays. Because much of the morbidity and mortal...

journal_title：Infection and immunity

authors： Su D,Roth RI,Yoshida M,Levin J

更新日期：1997-04-01 00:00:00

abstract：:Suitability of the rhesus monkey (Macaca mulatta) as an experimental host for evaluation of vaccines against airborne infection with Mycobacterium tuberculosis strain H37Rv was investigated. Nonvaccinated monkeys were exposed to estimated doses of 12, 25, or 49 units of H37Rv in a modified Henderson apparatus, and the...

journal_title：Infection and immunity

authors： Barclay WR,Anacker RL,Brehmer W,Leif W,Ribi E

更新日期：1970-11-01 00:00:00

abstract：:Naturally occurring antibodies for Vibrio fetus with whole-cell and O antigen specificities were detected in sera of mature cattle by means of the agglutination and indirect immunofluorescence reactions. O antibodies occurred in each of 21 sera examined, and whole-cell antibodies, in lower concentrations, occurred in ...

journal_title：Infection and immunity

authors： Duncan JR,Wilkie BN,Winter AJ

更新日期：1972-05-01 00:00:00

abstract：:Bacteria alter their cell surface in response to changing environments, including those encountered upon invasion of a host during infection. One alteration that occurs in several Gram-positive pathogens is the presentation of cell wall-anchored components of the iron-regulated surface determinant (Isd) system, which ...

journal_title：Infection and immunity

authors： Farrand AJ,Haley KP,Lareau NM,Heilbronner S,McLean JA,Foster T,Skaar EP

更新日期：2015-09-01 00:00:00

abstract：:Hepatitis, proliferative typhlitis, and colitis were characterized in young adult and older SCID/NCr mice naturally infected with Helicobacter hepaticus. Liver lesions consisted of Kupffer, Ito, and oval cell hyperplasia along with multifocal to coalescing coagulative hepatocyte necrosis. Numerous Warthin-Starry-posit...

journal_title：Infection and immunity

authors： Li X,Fox JG,Whary MT,Yan L,Shames B,Zhao Z

更新日期：1998-11-01 00:00:00

abstract：:Dissemination of Leishmania within the host is related to parasites undergoing unchecked proliferation. We therefore studied the effects of oxidant generating systems on promastigote multiplication by (i) direct determinations of organism proliferation and (ii) the incorporation of [3H]uracil into promastigote nucleop...

journal_title：Infection and immunity

authors： Reiner NE,Kazura JW

更新日期：1982-06-01 00:00:00

abstract：:γ9δ2 T cells provide a natural bridge between innate and adaptive immunity, rapidly and potently respond to pathogen infection in mucosal tissues, and are prominently induced by both tuberculosis (TB) infection and bacillus Calmette Guérin (BCG) vaccination. Mycobacterium-expanded γ9δ2 T cells represent only a subset ...

journal_title：Infection and immunity

authors： Xia M,Hesser DC,De P,Sakala IG,Spencer CT,Kirkwood JS,Abate G,Chatterjee D,Dobos KM,Hoft DF

更新日期：2016-08-19 00:00:00

abstract：:Each of the serotypes of Haemophilus influenzae (types a to f) may colonize the respiratory tract of humans, but only type b strains commonly cause invasive systemic infections. To investigate the role of complement in immunity to encapsulated non-type b strains, rats were depleted of C3 with cobra venom factor and ch...

journal_title：Infection and immunity

authors： Corrall CJ,Winkelstein JA,Moxon ER

更新日期：1982-03-01 00:00:00

abstract：:In the present investigation we studied the nature of a Shigella flexneri O antigen, the type III antigen. No structural entity has yet been attributed to this antigen. Phenol-water-extracted lipopolysaccharides (LPSs) from all S. flexneri serotypes possessing either group 6 antigen or both type III antigen and group ...

journal_title：Infection and immunity

authors： Carlin NI,Wehler T,Lindberg AA

更新日期：1986-07-01 00:00:00

abstract：:Antiserum and purified immunoglobulin directed against Mycoplasma pneumoniae membrane protein P1 were examined for their influence on mycoplasma viability, metabolism, and cytadsorption. Anti-P1 immunoglobulin inhibited adherence of M. pneumoniae to hamster tracheal rings in vitro by up to 80% and inhibited hemadsorpt...

journal_title：Infection and immunity

authors： Krause DC,Baseman JB

更新日期：1983-03-01 00:00:00

abstract：:Growth in colonies with type 1 morphology and the presence of pili are characteristics that have been associated with virulence of gonococci for humans. To determine whether the presence of pili per se might be responsible for colony type 1 morphology, the relationship of pili to colony type was examined in various sp...

journal_title：Infection and immunity

authors： McGee ZA,Dourmashkin RR,Gross JG,Clark JB,Taylor-Robinson D

更新日期：1977-02-01 00:00:00

abstract：:Candida albicans is a ubiquitous mucosal commensal that is normally prevented from causing acute or chronic invasive disease. Neutrophils contribute to protection in oral infection but exacerbate vulvovaginal candidiasis. To dissect the role of neutrophils during mucosal candidiasis, we took advantage of a new, transp...

journal_title：Infection and immunity

authors： Gratacap RL,Scherer AK,Seman BG,Wheeler RT

更新日期：2017-08-18 00:00:00

abstract：:Recent evidence suggests that immune-mediated gastric epithelial cell apoptosis through Fas-Fas ligand interactions participates in Helicobacter pylori disease pathogenesis. To define the role of Fas signaling in vivo, H. pylori strain SS1 infection in C57BL/6 mice was compared to that in mice deficient in the Fas lig...

journal_title：Infection and immunity

authors： Jones NL,Day AS,Jennings H,Shannon PT,Galindo-Mata E,Sherman PM

更新日期：2002-05-01 00:00:00

abstract：:Legionella pneumophila is a gram-negative facultative intracellular parasite of macrophages. Although L. pneumophila is the causative agent of a severe pneumonia known as Legionnaires' disease, it is likely that most infections caused by this organism are cleared by the host innate immune system. It is predicted that ...

journal_title：Infection and immunity

authors： Archer KA,Roy CR

更新日期：2006-06-01 00:00:00

abstract：:The aroC gene of the facultative intracellular pathogen Brucella suis was cloned and sequenced. The cloned aroC gene complements Escherichia coli and Salmonella enterica serovar Typhimurium aroC mutants. A B. suis aroC mutant was found to be unable to grow in a defined medium without aromatic compounds. The mutant was...

journal_title：Infection and immunity

authors： Foulongne V,Walravens K,Bourg G,Boschiroli ML,Godfroid J,Ramuz M,O'Callaghan D

更新日期：2001-01-01 00:00:00

abstract：:The protective efficacy of Mycobacterium bovis BCG can be markedly augmented by stable integration of Mycobacterium tuberculosis genomic region RD1. BCG complemented with RD1 (BCG::RD1) encodes nine additional proteins. Among them, 10-kDa culture filtrate protein (CFP-10) and ESAT-6 (6-kDa early secreted antigenic tar...

journal_title：Infection and immunity

authors： Demangel C,Brodin P,Cockle PJ,Brosch R,Majlessi L,Leclerc C,Cole ST

更新日期：2004-04-01 00:00:00

abstract：:Staphylococcus aureus is an important pathogen of humans and other animals, causing bacteremia, abscesses, endocarditis, and other infectious syndromes. A signature-tagged mutagenesis (STM) system was adapted for use in studying the genes required for in vivo survival of S. aureus. An STM library was ultimately create...

journal_title：Infection and immunity

authors： Schwan WR,Coulter SN,Ng EY,Langhorne MH,Ritchie HD,Brody LL,Westbrock-Wadman S,Bayer AS,Folger KR,Stover CK

更新日期：1998-02-01 00:00:00

abstract：:Peptidoglycan (PG) turnover in exponentially growing Neisseria gonorrhoeae RD5 type 4 was accompanied by release of soluble PG fragments into the medium. Turnover of the D-[14C]glucosamine-labeled glycan moiety and of the meso-[3H]diaminopimelic acid (DAP)-labeled peptide region occurred at similar rates (ca. 35% per ...

journal_title：Infection and immunity

authors： Rosenthal RS

更新日期：1979-06-01 00:00:00

abstract：:Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn's disease (CD). Mechanisms that favor fibrosis are not well understood, and therapeutic strategies are limited. Here we demonstrate that colitis-susceptible Il10-deficient mice dev...

journal_title：Infection and immunity

authors： Ellermann M,Gharaibeh RZ,Fulbright L,Dogan B,Moore LN,Broberg CA,Lopez LR,Rothemich AM,Herzog JW,Rogala A,Gordon IO,Rieder F,Brouwer CR,Simpson KW,Jobin C,Sartor RB,Arthur JC

更新日期：2019-10-18 00:00:00

abstract：:We used the Salmonella typhi galactose epimerase (galE) mutant strain Ty21a, shown to be a safe, effective, living, attenuated oral typhoid vaccine, as a recipient for a recombinant plasmid containing the gene for production of the nontoxic B subunit of the heat-labile enterotoxin of Escherichia coli. The S. typhi der...

journal_title：Infection and immunity

authors： Clements JD,El-Morshidy S

更新日期：1984-11-01 00:00:00

abstract：:We determined the heavy (H)- and light (L)-chain variable (V) region nucleotide and translated amino acid sequences of the human immunoglobulin M(kappa) monoclonal antibody (MAb) 5E1, which is specific for the polysaccharide capsule of Escherichia coli K1 and Neisseria meningitidis group B (poly[alpha(2-->8)-N-acetyln...

journal_title：Infection and immunity

authors： Azmi FH,Lucas AH,Raff HV,Granoff DM

更新日期：1994-05-01 00:00:00

abstract：:Protective immunity against Toxoplasma gondii is known to be mediated mainly by T lymphocytes and gamma interferon (IFN-gamma). The contribution of CD4(+) and CD8(+) T-lymphocyte subsets to protective immune responses against T. gondii infection, triggered by a GRA1 (p24) DNA vaccine, was assessed in this study. In vi...

journal_title：Infection and immunity

authors： Scorza T,D'Souza S,Laloup M,Dewit J,De Braekeleer J,Verschueren H,Vercammen M,Huygen K,Jongert E

更新日期：2003-01-01 00:00:00

abstract：:The Yersinia high-pathogenicity island (HPI) is common to multiple virulence strategies used by Escherichia coli strains associated with urinary tract infection (UTI). Among the genes in this island are ybtP and ybtQ, encoding distinctive ATP binding cassette (ABC) proteins associated with iron(III)-yersiniabactin imp...

journal_title：Infection and immunity

authors： Koh EI,Hung CS,Henderson JP

更新日期：2016-04-22 00:00:00

abstract：:Dendritic cell interactions with pathogenic microbes initiate and direct the development of subsequent adaptive responses. The protozoan pathogen Giardia lamblia infects the mammalian small intestine, leading to nutrient malabsorption and diarrhea but rarely causing inflammation. In order to begin to understand how th...

journal_title：Infection and immunity

authors： Kamda JD,Singer SM

更新日期：2009-02-01 00:00:00

abstract：:The adhesion of gram-positive bacteria to extracellular matrix (ECM) proteins is regarded as an important determinant of pathogenicity. A comparison of the adhesion of Streptococcus agalactiae strain O90R to different ECM proteins showed that the most pronounced binding could be observed for immobilized fibrinogen. To...

journal_title：Infection and immunity

authors： Spellerberg B,Rozdzinski E,Martin S,Weber-Heynemann J,Lütticken R

更新日期：2002-05-01 00:00:00

abstract：:This work evaluated the kinetics of events that occur in the placenta of Calomys callosus after Toxoplasma gondii infection. Animals on the first day of pregnancy (dop) and virgin nonpregnant females were perorally infected with 20 cysts of T. gondii strain ME49. After 100 days of infection, the virgin animals were ma...

journal_title：Infection and immunity

authors： Ferro EA,Silva DA,Bevilacqua E,Mineo JR

更新日期：2002-12-01 00:00:00