Uropathogenic Escherichia coli CFT073 is adapted to acetatogenic growth but does not require acetate during murine urinary tract infection.

abstract：:We previously reported that infection by Fusobacterium nucleatum strongly induced the expression of both human beta-defensin 2 (HBD-2) and HBD-3 by gingival epithelial cells. The aim of this study was to characterize the pattern recognition receptors (PRRs) and regulatory mechanisms involved in the induction of HBD-2 ...

journal_title：Infection and immunity

authors： Ji S,Shin JE,Kim YS,Oh JE,Min BM,Choi Y

更新日期：2009-03-01 00:00:00

abstract：:Cholera toxin has been widely used to obtain insight into the cellular dynamics of the antigen-specific mucosal immune response. The present study was undertaken to clarify the influence of the organized intestinal lymphoid tissue (Peyer's patches [PP]) on the distribution of anti-cholera-toxin-containing cells (ACC) ...

journal_title：Infection and immunity

authors： Enders GA,Delius M,Ballhaus S,Brendel W

更新日期：1987-09-01 00:00:00

abstract：:Malaria elimination efforts would benefit from vaccines that block transmission of Plasmodium falciparum gametocytes from humans to mosquitoes. A clear understanding of gametocyte-specific antibody responses in exposed populations could help determine whether transmission-blocking vaccines (TBV) would be boosted by na...

journal_title：Infection and immunity

authors： Skinner J,Huang CY,Waisberg M,Felgner PL,Doumbo OK,Ongoiba A,Kayentao K,Traore B,Crompton PD,Williamson KC

更新日期：2015-11-01 00:00:00

abstract：:Strains of indigenous Escherichia coli, Bacteroides, and Lactobacillus were isolated from the gastrointestinal tracts of specific pathogen-free (SPF) mice. Nonvaccinated SPF mice exhibited in their spleens low numbers of plaque-forming cells (PFC) and rosette-forming cells reacting with antigens of these andigenous ba...

journal_title：Infection and immunity

authors： Berg RD,Savage DC

更新日期：1975-02-01 00:00:00

abstract：:A virus, 78-238, isolated from the cerebrospinal fluid of a dog with neurological dysfunction, was characterized as a paramyxovirus. This conclusion was supported by viral cytopathic effects and morphological appearance of virions and nucleocapsids in infected cells. Nucleocapsids were found in the cytoplasm of all in...

journal_title：Infection and immunity

authors： Baumgärtner WK,Metzler AE,Krakowka S,Koestner A

更新日期：1981-03-01 00:00:00

abstract：:The expression of T cell differentiation markers is known to increase during Mycobacterium tuberculosis infection, and yet the biological role of such markers remains unclear. We examined the requirement of the T cell differentiation marker killer cell lectin-like receptor G1 (KLRG1) during M. tuberculosis infection u...

journal_title：Infection and immunity

authors： Cyktor JC,Carruthers B,Stromberg P,Flaño E,Pircher H,Turner J

更新日期：2013-04-01 00:00:00

abstract：:Attempts were made to isolate an antigen(s) from Candida albicans suitable for detecting hypersensitivity in a murine model of candidiasis. Using footpad reactivity in cutaneously infected animals as the assay, comparisons were made of two commercial extracts and cell wall and cytoplasmic preparations made in the labo...

journal_title：Infection and immunity

authors： Domer JE,Moser SA

更新日期：1978-04-01 00:00:00

abstract：:In order to plan for the wide-scale introduction of meningococcal C conjugate (MCC) vaccine for United Kingdom children up to 18 years old, phase II trials were undertaken to investigate whether there was any interaction between MCC vaccines conjugated to tetanus toxoid (TT) or a derivative of diphtheria toxin (CRM(19...

journal_title：Infection and immunity

authors： Burrage M,Robinson A,Borrow R,Andrews N,Southern J,Findlow J,Martin S,Thornton C,Goldblatt D,Corbel M,Sesardic D,Cartwight K,Richmond P,Miller E

更新日期：2002-09-01 00:00:00

abstract：:Immunochemically identical components were isolated from water-soluble phases of five Staphylococcus aureus strains by affinity chromatography on fibrinogen-linked Sepharose 4B. The elution was performed with 1 M MgCl2. The component could be isolated from sonicated preparations of whole cells, cell walls, and extrace...

journal_title：Infection and immunity

authors： Espersen F,Clemmensen I,Barkholt V

更新日期：1985-09-01 00:00:00

abstract：:Protection against infection with virulent blood (trypomastigote) forms of Trypanosoma cruzi was accomplished in mice by immunization with culture (mainly epimastigote) forms killed by treatment with sodium perchlorate. Sodium chloride, used instead of sodium perchlorate, with all other conditions kept the same, faile...

journal_title：Infection and immunity

authors： Kierszenbaum F,Budzko DB

更新日期：1975-09-01 00:00:00

abstract：:Tox-+ staphylococcal strains, as opposed to Tox-minus strains, produce epidermal exfoliation within 18 h after direct subcutaneous or intraperitoneal injection into newborn mice. The extracellular product responsible for exfoliation is termed exfoliative toxin (ET). When culture supernatant fluid from the plasmid-cure...

journal_title：Infection and immunity

authors： Keyhani M,Rogolsky M,Wiley BB,Glasgow LA

更新日期：1975-07-01 00:00:00

abstract：:Susceptibility of Syrian hamsters of the inbred LSH and MHA strains to injection of as few as 10 plaque-forming units of vesicular stomatitis virus (VSV) was shown to occur only after intraperitoneal and intrapleural injection and not after injection of VSV intravenously, intranasally, or in the footpads. Despite the ...

journal_title：Infection and immunity

authors： Fultz PN,Shadduck JA,Kang CY,Streilein JW

更新日期：1981-11-01 00:00:00

abstract：:The mouse humoral immune response toward native or detergent-extracted outer membrane vesicles (NOMVs and DOMVs, respectively) from Neisseria meningitidis was determined after intranasal immunization. Both preparations elicited high frequencies of NOMV-specific antibody-forming cells (AFCs) locally in the nasal associ...

journal_title：Infection and immunity

authors： Guthrie T,Wong SY,Liang B,Hyland L,Hou S,Høiby EA,Andersen SR

更新日期：2004-05-01 00:00:00

abstract：:In this study, we examined the binding of Candida albicans synchronized yeast-phase cells to plastic, immobilized amino acids and bovine serum albumin (BSA) and quantified the binding by using an XTT tetrazolium salt assay and absorbance determination. Our results show that C. albicans binds efficiently and specifical...

journal_title：Infection and immunity

authors： Hawser SP,Islam K

更新日期：1998-01-01 00:00:00

abstract：:Existing evidence suggests that oxidative insults and antioxidant defense mechanisms play a critical role in the host cell response during infection of endothelial cells by Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever. Heme oxygenase (HO), a rate-limiting enzyme in the pathway for heme ca...

journal_title：Infection and immunity

authors： Rydkina E,Sahni A,Silverman DJ,Sahni SK

更新日期：2002-08-01 00:00:00

abstract：:Ocular inflammation is one of the consequences of infection with the protozoan parasite Toxoplasma gondii. Even if lesions are self-healing in immunocompetent persons, they pose a lifetime risk of reactivation and are a serious threat to vision. As there are virtually no immunological data on reactivating ocular toxop...

journal_title：Infection and immunity

authors： Rochet É,Brunet J,Sabou M,Marcellin L,Bourcier T,Candolfi E,Pfaff AW

更新日期：2015-05-01 00:00:00

abstract：:The multiple antigen peptide (MAP) approach is an effective method to chemically synthesize and deliver multiple T-cell and B-cell epitopes as the constituents of a single immunogen. Here we report on the design, chemical synthesis, and immunogenicity of three Plasmodium falciparum MAP vaccines that incorporated antig...

journal_title：Infection and immunity

authors： Mahajan B,Berzofsky JA,Boykins RA,Majam V,Zheng H,Chattopadhyay R,de la Vega P,Moch JK,Haynes JD,Belyakov IM,Nakhasi HL,Kumar S

更新日期：2010-11-01 00:00:00

abstract：:Spleen cells from BALB/c mice infected with 2 X 10(7) L. major promastigotes and developing progressive disease produced significantly lower levels of interleukin-2 (IL-2) in response to concanavalin A stimulation than did spleen cells from uninfected mice. In contrast, spleen cells from sublethally irradiated and inf...

journal_title：Infection and immunity

authors： Cillari E,Liew FY,Lelchuk R

更新日期：1986-11-01 00:00:00

abstract：:To develop targeted gene integration in the periodontal pathogen Actinobacillus actinomycetemcomitans, a ColE1-based, spectinomycin-resistant plasmid containing a segment of the leukotoxin gene was electroporated into strain JP2. In all of the stable spectinomycin-resistant transformants that arose, the plasmid had re...

journal_title：Infection and immunity

authors： Kolodrubetz D,Phillips LH,Ezzo PJ,Kraig E

更新日期：1995-07-01 00:00:00

abstract：:Infection of mice with the murine sarcoma virus (Moloney) markedly suppressed the humoral antibody response to sheep erythrocyte antigen injected 10 days after infection, when tumor size was maximal, and on day 26, when primary tumors had partially regressed. Humoral antibody response was also inhibited when antigen w...

journal_title：Infection and immunity

authors： Chan SP,Hook WA,Turner W,Chirigos MA

更新日期：1970-03-01 00:00:00

abstract：:The adhesion of gram-positive bacteria to extracellular matrix (ECM) proteins is regarded as an important determinant of pathogenicity. A comparison of the adhesion of Streptococcus agalactiae strain O90R to different ECM proteins showed that the most pronounced binding could be observed for immobilized fibrinogen. To...

journal_title：Infection and immunity

authors： Spellerberg B,Rozdzinski E,Martin S,Weber-Heynemann J,Lütticken R

更新日期：2002-05-01 00:00:00

abstract：:Bordetella bronchiseptica is closely related to Bordetella pertussis, which produces respiratory disease primarily in mammals other than humans. However, its importance as a human pathogen is being increasingly recognized. Although a large amount of research on Bordetella has been generated regarding protein virulence...

journal_title：Infection and immunity

authors： Sisti F,Fernández J,Rodríguez ME,Lagares A,Guiso N,Hozbor DF

更新日期：2002-04-01 00:00:00

abstract：:Cell wall lytic enzyme (Kyowa lytic no. 2 enzyme) liberated arthritogenic hydrosoluble peptidoglycans from both arthritogenic and non-arthritogenic bacterial cell walls. From these cell walls, mutanolysin (peptidoglycan-degrading enzyme) also liberated hydrosoluble peptidoglycans which, however, lacked arthritogenicit...

journal_title：Infection and immunity

authors： Kohashi O,Pearson CM,Watanabe Y,Kotani S

更新日期：1977-06-01 00:00:00

abstract：:Nonspecific interactions related to physicochemical properties of bacterial cell surfaces, such as hydrophobicity and electrostatic charge, are known to have important roles in bacterium-host cell encounters. Streptococcus pneumoniae (pneumococcus) expresses multiple, surface-exposed, choline-binding proteins (CBPs) w...

journal_title：Infection and immunity

authors： Swiatlo E,Champlin FR,Holman SC,Wilson WW,Watt JM

更新日期：2002-01-01 00:00:00

abstract：:A toxin associated with Toxoplasma gondii infection was obtained from the trophozoites and culture medium used to propagate the parasite in cell cultures. The toxin, named Toxofactor (TF), administered parenterally or nonparenterally in adult mice, produces transient symptoms of lethargy, ruffled fur, and body weight ...

journal_title：Infection and immunity

authors： Grimwood B,O'Connor G,Gaafar HA

更新日期：1983-12-01 00:00:00

abstract：:Cultures of Serpulina pilosicoli 95/1000, isolated from a pig with porcine intestinal spirochetosis (PIS), and S. pilosicoli WesB, isolated from an Aboriginal child with diarrhea, were used to infect 5-week-old newly weaned pigs. Four of 12 pigs infected with strain 95/1000 and 2 of 12 pigs infected with strain WesB b...

journal_title：Infection and immunity

authors： Trott DJ,Huxtable CR,Hampson DJ

更新日期：1996-11-01 00:00:00

abstract：:Adherence of blastoconidia to epidermal corneocytes is an early event in Candida colonization and infection of the skin. Pathogenic species adhere more avidly than nonpathogenic species, transform to hyphal growth, and invade the stratum corneum of the skin. Adherence was studied by scanning electron microscopy of exp...

journal_title：Infection and immunity

authors： Ray TL,Payne CD

更新日期：1988-08-01 00:00:00

abstract：:Interleukin-10 (IL-10)-producing B cells (B10 cells) play a critical role in the immune system balance by negatively regulating inflammatory responses. This study was conducted to determine the effect of local B10 cell induction on periodontal inflammation and bone loss in ligature-induced experimental periodontitis i...

journal_title：Infection and immunity

authors： Yu P,Hu Y,Liu Z,Kawai T,Taubman MA,Li W,Han X

更新日期：2016-12-29 00:00:00

abstract：:Whereas infections of macrophages by promastigote forms of Leishmania mexicana pifanoi induce the production of superoxide, infections by amastigotes barely induce superoxide production. Several approaches were employed to gain insight into the mechanism by which amastigotes avoid eliciting superoxide production. Firs...

journal_title：Infection and immunity

authors： Pham NK,Mouriz J,Kima PE

更新日期：2005-12-01 00:00:00

abstract：:Some interrelationships among age, ambient temperature, intestinal transit, and enterotoxigenic Escherichia coli infection were studied in an infant mouse model. The transit of dye in the small intestine was accelerated during the response to heat-stable E. coli enterotoxin. Transit in the small intestine of normal mi...

journal_title：Infection and immunity

authors： Moon HW,Fung PY,Isaacson RE,Booth GD

更新日期：1979-07-01 00:00:00