Role of Peyer's patch in the intestinal immune response to cholera toxin in enterically immunized rats.

abstract：:Modification of three or four of the five histidine residues in the toxic shock syndrome toxin 1 (TSST-1) with diethylpyrocarbonate did not inhibit the precipitin reaction of the modified TSST-1 with polyvalent antisera to the toxin. Monoclonal antibody 7T did not react with the modified TSST-1, but monoclonal antibod...

journal_title：Infection and immunity

authors： Kokan-Moore NP,Bergdoll MS

更新日期：1989-07-01 00:00:00

abstract：:There is an emerging paradigm shift from coronary heart disease having a purely hereditary and nutritional causation to possibly having an infectious etiology. Recent epidemiological studies have shown a correlation between periodontal disease and coronary heart disease. However, to date, there is minimal information ...

journal_title：Infection and immunity

authors： Dorn BR,Dunn WA Jr,Progulske-Fox A

更新日期：1999-11-01 00:00:00

abstract：:Woodchuck sera were tested for antigens and antibodies with tests which detect human hepatitis virus antigens and antibodies. Data on 264 woodchuck sera are presented. ...

journal_title：Infection and immunity

authors： Millman I,Halbherr T,Simmons H

更新日期：1982-02-01 00:00:00

abstract：:Haemophilus ducreyi, the etiologic agent of the sexually transmitted disease chancroid, has been shown to inhibit phagocytosis of both itself and secondary targets in vitro. Immunodepletion of LspA proteins from H. ducreyi culture supernatant fluid abolished this inhibitory effect, indicating that the LspA proteins ar...

journal_title：Infection and immunity

authors： Mock JR,Vakevainen M,Deng K,Latimer JL,Young JA,van Oers NS,Greenberg S,Hansen EJ

更新日期：2005-12-01 00:00:00

abstract：:We have reported that P388D1 cell line murine macrophages stimulated with lipopolysaccharide (LPS) from Actinobacillus actinomycetemcomitans release interleukin-1 (IL-1) inhibitor. The IL-1 inhibitor was purified from conditioned media of P388D1 cells stimulated with A. actinomycetemcomitans LPS for 72 h to homogeneit...

journal_title：Infection and immunity

authors： Nishihara T,Ohsaki Y,Ueda N,Saito N,Mundy GR

更新日期：1994-02-01 00:00:00

abstract：:High levels of Treponema denticola in subgingival dental plaque are associated with severe periodontal disease. T. denticola, along with Porphyromonas gingivalis and Bacteroides forsythus, are the only cultivatable oral microorganisms that produce significant amounts of "trypsin-like" peptidase activity. The ability o...

journal_title：Infection and immunity

authors： Fenno JC,Lee SY,Bayer CH,Ning Y

更新日期：2001-10-01 00:00:00

abstract：:To produce chronic infection, microbial pathogens must escape host immune defenses. Infection with the human pathogenic fungus Cryptococcus neoformans is typically chronic. To understand the mechanism by which C. neoformans survives in tissue after the infection of immunocompetent hosts, we systematically studied the ...

journal_title：Infection and immunity

authors： Feldmesser M,Kress Y,Novikoff P,Casadevall A

更新日期：2000-07-01 00:00:00

abstract：:A receptor specific for lipoglycans from Acholeplasma axanthum and Acholeplasma granularum was isolated from sheep erythrocyte stroma by extraction with n-pentanol and permeation chromatography. The purified receptor appeared as one band on sodium dodecyl sulfate-polyacrylamide gels and stained with Coomassie blue, pe...

journal_title：Infection and immunity

authors： Al-Samarrai TH,Smith PF,Lynn RJ

更新日期：1982-12-01 00:00:00

abstract：:Paracoccidioidomycosis patients show hyperactive humoral immune responses. Consequently, we investigated whether cytokines in supernatants from Paracoccidioides brasiliensis-stimulated gamma/delta T cells support B-cell activation. We detected proliferation of B cells and increased immunoglobulin M (IgM) and IgG produ...

journal_title：Infection and immunity

authors： Munk ME,Fazioli RA,Calich VL,Kaufmann SH

更新日期：1995-04-01 00:00:00

abstract：:Toll-like receptor (TLR) signal transduction is a central component of the innate immune response to pathogenic challenge. Although recent studies have begun to elucidate differences in acquired immunity in tissues of the human female reproductive tract, there is a relative paucity of work regarding innate defense mec...

journal_title：Infection and immunity

authors： Pioli PA,Amiel E,Schaefer TM,Connolly JE,Wira CR,Guyre PM

更新日期：2004-10-01 00:00:00

abstract：:We examined the immunobiological responses to Histoplasma capsulatum in lungs of gamma interferon (IFN-gamma) knockout mice (GKO mice). Naive GKO mice succumbed by day 9 to intranasal challenge with 2.5 x 10(6) yeasts, whereas all wild-type (WT) mice survived for 45 days. Compared to lungs of WT mice, the lungs of acu...

journal_title：Infection and immunity

authors： Allendoerfer R,Deepe GS Jr

更新日期：1997-07-01 00:00:00

abstract：:We investigated the effect of the extracellular protease of Serratia marcescens on human serum constituents such as immunoglobulins, fibronectin, alpha 1-protease inhibitor, alpha 2-macroglobulin, lysozyme, and transferrin. At a very low concentration of Serratia 56-kilodalton protease (56K protease), purified human p...

journal_title：Infection and immunity

authors： Molla A,Matsumoto K,Oyamada I,Katsuki T,Maeda H

更新日期：1986-09-01 00:00:00

abstract：:Fimbriae, lipopolysaccharide (LPS), and extracellular polymeric substance (EPS) all contribute to biofilm formation by the periodontopathogen Aggregatibacter actinomycetemcomitans. To understand how individual biofilm determinants respond to changing environmental conditions, the transcription of genes responsible for...

journal_title：Infection and immunity

authors： Amarasinghe JJ,Scannapieco FA,Haase EM

更新日期：2009-07-01 00:00:00

abstract：:The type III secretion system (T3SS) of pathogenic bordetellae employs a self-associating tip complex protein Bsp22. This protein is immunogenic during infections by Bordetella bronchiseptica and could be used as a protective antigen to immunize mice against B. bronchiseptica challenge. Since low-passage clinical isol...

journal_title：Infection and immunity

authors： Villarino Romero R,Bibova I,Cerny O,Vecerek B,Wald T,Benada O,Zavadilova J,Osicka R,Sebo P

更新日期：2013-08-01 00:00:00

abstract：:C4BP (C4b-binding protein) is a high-molecular-weight plasma protein that inhibits the classical pathway of complement activation. Recent experiments have demonstrated that C4BP binds to many strains of the gram-positive bacterium Streptococcus pyogenes, a major respiratory tract pathogen. Binding to S. pyogenes was s...

journal_title：Infection and immunity

authors： Berggård K,Johnsson E,Mooi FR,Lindahl G

更新日期：1997-09-01 00:00:00

abstract：:Bacterial infection with group B Streptococcus (GBS) represents a prominent threat to neonates and fetuses in the Western world, causing severe organ damage and even death. To improve current therapeutic strategies and to investigate new approaches, an appropriate in vivo model to study the immune response of a human ...

journal_title：Infection and immunity

authors： Ernst W,Zimara N,Hanses F,Männel DN,Seelbach-Göbel B,Wege AK

更新日期：2013-05-01 00:00:00

abstract：:Escherichia coli strain RDEC-1 causes a diarrheagenic infection in rabbits with AF/R1 fimbriae, which have been identified as an important colonization factor in RDEC-1 adherence leading to disease. The AF/R1-mediated RDEC-1 adherence model has been used as a model systems for E. coli diarrheal diseases. In this study...

journal_title：Infection and immunity

authors： Ryu H,Kim YS,Grange PA,Cassels FJ

更新日期：2001-02-01 00:00:00

abstract：:Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent approach, using multiple-antigen vaccines (MAV) prepared from S. pneumoniae TIGR4...

journal_title：Infection and immunity

authors： Chan WY,Entwisle C,Ercoli G,Ramos-Sevillano E,McIlgorm A,Cecchini P,Bailey C,Lam O,Whiting G,Green N,Goldblatt D,Wheeler JX,Brown JS

更新日期：2019-02-21 00:00:00

abstract：:Microbial heat shock proteins (HSP) are dominant antigens for the host immune response. Because of the high sequence homology between mammalian and microbial HSP, their value as component of a subunit vaccine has been the subject of controversy. Previous work from this laboratory, however, demonstrated for the first t...

journal_title：Infection and immunity

authors： Noll A,AutenriethIB

更新日期：1996-08-01 00:00:00

abstract：:The identification of genes with increased expression in vivo may lead to the identification of novel or unrecognized virulence traits and/or recognition of environmental signals involved in modulating gene expression. Our laboratory is studying an extraintestinal isolate of Escherichia coli as a model pathogen. We ha...

journal_title：Infection and immunity

authors： Russo TA,Carlino UB,Mong A,Jodush ST

更新日期：1999-10-01 00:00:00

abstract：:Mycobacterium tuberculosis, the primary etiologic agent of tuberculosis, is the world's leading cause of death from a single infectious agent, and new vaccines and drugs to combat it are urgently needed. The major extracellular proteins of M. tuberculosis, which are released into its phagosome in macrophages, its host...

journal_title：Infection and immunity

authors： Harth G,Lee BY,Horwitz MA

更新日期：1997-06-01 00:00:00

abstract：:Neisseria gonorrhoeae enters cultured human mucosal cells following binding of a distinct gonococcal opacity (Opa) outer membrane protein to cell surface proteoglycan receptors. We examined the route of internalization that is activated by Opa-expressing gonococci (strain VP1). Microscopy of infected Chang epithelial ...

journal_title：Infection and immunity

authors： Grassmé HU,Ireland RM,van Putten JP

更新日期：1996-05-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4), which recognizes lipopolysaccharide from Gram-negative bacteria, plays a major role in resistance of mice and humans to Salmonella infection. In chickens, Salmonella may establish a carrier state whereby bacteria are able to persist in the host organism without triggering clinical signs. B...

journal_title：Infection and immunity

authors： Chaussé AM,Grépinet O,Bottreau E,Le Vern Y,Menanteau P,Trotereau J,Robert V,Wu Z,Kerboeuf D,Beaumont C,Velge P

更新日期：2011-08-01 00:00:00

abstract：:We investigated the effect of an extract from a helminth (Ascaris suum) in zymosan-induced arthritis (ZYA) or collagen-induced arthritis (CIA). Rats and mice, respectively, received 1 mg and 0.1 mg zymosan intra-articularly (i.a.). Test groups received an A. suum extract either per os (p.o.) or intraperitoneally (i.p....

journal_title：Infection and immunity

authors： Rocha FA,Leite AK,Pompeu MM,Cunha TM,Verri WA Jr,Soares FM,Castro RR,Cunha FQ

更新日期：2008-06-01 00:00:00

abstract：:Previous studies suggested that nontypeable Haemophilus influenzae (NTHI) can form biofilms during human and chinchilla middle ear infections. Microscopic analysis of a 5-day biofilm of NTHI strain 2019 grown in a continuous-flow chamber revealed that the biofilm had a diffuse matrix interlaced with multiple water cha...

journal_title：Infection and immunity

authors： Greiner LL,Watanabe H,Phillips NJ,Shao J,Morgan A,Zaleski A,Gibson BW,Apicella MA

更新日期：2004-07-01 00:00:00

abstract：:We previously reported that two surface-exposed high-molecular-weight proteins, HMW1 and HMW2, expressed by a prototypic strain of nontypeable Haemophilus influenzae (NTHI) mediate attachment to human epithelial cells. These proteins are members of a family of highly immunogenic proteins common to most nontypeable Hae...

journal_title：Infection and immunity

authors： Barenkam SJ,St Geme JW 3rd

更新日期：1996-08-01 00:00:00

abstract：:The leukotrienes and tumor necrosis factor (TNF) play an important role in the pathophysiology of septic shock, in which hypotension, leukopenia, thrombocytopenia, and hemoconcentration are observed. This study was performed to examine the effects of a 5-lipoxygenase inhibitor (AA-861), a selective leukotriene recepto...

journal_title：Infection and immunity

authors： Ogata M,Matsumoto T,Kamochi M,Yoshida SI,Mizuguchi Y,Shigematsu A

更新日期：1992-06-01 00:00:00

abstract：:A set of four monoclonal antibodies was produced against a highly purified pepsin extract of type 5 streptococcal M protein. Three of the four antibodies cross-reacted with purified M proteins from heterologous serotypes and opsonized the respective heterologous organisms. Our studies suggest that monoclonal antibodie...

journal_title：Infection and immunity

authors： Dale JB,Beachey EH

更新日期：1984-10-01 00:00:00

abstract：:Resistance against acute and chronic infection with Taxoplasma gondii in BALB/c and CBA/Ca mice was compared. Intraperitoneal inoculation of either 20, 40, or 80 cysts of the ME49 strain resulted in mortality rates in BALB/c mice of 12% (2 of 17), 50% (6 of 12), and 75% (9 of 12), respectively, within 3 weeks after in...

journal_title：Infection and immunity

authors： Suzuki Y,Orellana MA,Wong SY,Conley FK,Remington JS

更新日期：1993-06-01 00:00:00

abstract：:Previous studies have demonstrated that the Moraxella catarrhalis surface antigen UspA1 is an adhesin for Chang human conjunctival cells. The present report demonstrates that lack of UspA1 expression does not affect the adherence of strain O35E to A549 human lung cells or primary cultures of human middle ear epithelia...

journal_title：Infection and immunity

authors： Holm MM,Vanlerberg SL,Sledjeski DD,Lafontaine ER

更新日期：2003-09-01 00:00:00