Protective effect of an extract from Ascaris suum in experimental arthritis models.

abstract：:Salmonella enterica serovar Typhimurium causes self-limiting gastroenteritis in humans and a typhoid-like disease in mice that serves as a model for typhoid infections in humans. A critical step in Salmonella pathogenesis is the invasion of enterocytes and M cells of the small intestine via expression of a type III se...

journal_title：Infection and immunity

authors： Boddicker JD,Jones BD

更新日期：2004-04-01 00:00:00

abstract：:Bovine digital dermatitis (BDD), an infectious disease of the bovine foot with a predominant treponemal etiology, is a leading cause of lameness in dairy and beef herds worldwide. BDD is poorly responsive to antimicrobial therapy and exhibits a relapsing clinical course; an effective vaccine is therefore urgently soug...

journal_title：Infection and immunity

authors： Staton GJ,Carter SD,Ainsworth S,Mullin J,Smith RF,Evans NJ

更新日期：2020-04-20 00:00:00

abstract：:Whooping cough results from infection of the respiratory tract with Bordetella pertussis, and the secreted adenylate cyclase toxin (ACT) is essential for the bacterium to establish infection. Despite extensive study of the mechanism of ACT cytotoxicity and its effects over a range of concentrations in vitro, ACT has n...

journal_title：Infection and immunity

authors： Eby JC,Gray MC,Warfel JM,Paddock CD,Jones TF,Day SR,Bowden J,Poulter MD,Donato GM,Merkel TJ,Hewlett EL

更新日期：2013-05-01 00:00:00

abstract：:Lyme disease (LD), the most prevalent tick-borne illness in North America, is caused by Borrelia burgdorferi The long-term survival of B. burgdorferi spirochetes in the mammalian host is achieved though VlsE-mediated antigenic variation. It is mathematically predicted that a highly variable surface antigen prolongs ba...

journal_title：Infection and immunity

authors： Rogovskyy AS,Gillis DC,Ionov Y,Gerasimov E,Zelikovsky A

更新日期：2016-12-29 00:00:00

abstract：:Most Helicobacter pylori strains express the BabA adhesin, which binds to ABO/Leb blood group antigens on gastric mucin and epithelial cells and is found more commonly in strains that cause peptic ulcers or gastric cancer, rather than asymptomatic infection. We and others have previously reported that in mice, gerbils...

journal_title：Infection and immunity

authors： Hansen LM,Gideonsson P,Canfield DR,Borén T,Solnick JV

更新日期：2017-05-23 00:00:00

abstract：:In malarial infections of primates, the spleen has been shown to modulate parasite antigen expression on the surfaces of infected erythrocytes. The processes affected include cytoadherence, which is central to the pathophysiology of severe falciparum malaria, and the related phenomenon of rosette formation. In this st...

journal_title：Infection and immunity

authors： Ho M,Bannister LH,Looareesuwan S,Suntharasamai P

更新日期：1992-06-01 00:00:00

abstract：:Treatment with nontoxic monophosphoryl lipid A (MPL), which was derived from a polysaccharide-deficient, heptoseless Re mutant of Salmonella typhimurium, was found to inactivate suppressor T-cell activity, as evidenced by a decrease in the degree of low-dose immunological paralysis expressed and an increase in the mag...

journal_title：Infection and immunity

authors： Baker PJ,Hiernaux JR,Fauntleroy MB,Prescott B,Cantrell JL,Rudbach JA

更新日期：1988-05-01 00:00:00

abstract：:The effect of continuous exposure to 80% oxygen on newborn mice with Ureaplasma urealyticum pneumonia was determined. Mice were inoculated intranasally with either U. urealyticum or sterile broth and then housed in either 80% oxygen or room air (21% oxygen). The mice were sacrificed at either 7 or 14 days after inocul...

journal_title：Infection and immunity

authors： Crouse DT,Cassell GH,Waites KB,Foster JM,Cassady G

更新日期：1990-11-01 00:00:00

abstract：:The combining sites of type 1 fimbrial lectins of various species of enterobacteria were studied by measuring the inhibitory activity of linear and branched oligosaccharides and several glycosides of D-mannose on the agglutination of yeast cells by the organisms. The results showed that all five strains of Escherichia...

journal_title：Infection and immunity

authors： Firon N,Ofek I,Sharon N

更新日期：1984-03-01 00:00:00

abstract：:Exposure to bacterial superantigens such as staphylococcal enterotoxin B (SEB) leads to the induction of toxic shock syndrome which results in multiorgan failure, including liver damage. In the present study, we investigated the role of CD44 in SEB-induced liver injury. Injection of SEB into d-galactosamine-sensitized...

journal_title：Infection and immunity

authors： McKallip RJ,Fisher M,Gunthert U,Szakal AK,Nagarkatti PS,Nagarkatti M

更新日期：2005-01-01 00:00:00

abstract：:The cytoskeletal lesions associated with enteropathogenic Escherichia coli adhering to cultured HeLa epithelial cells were examined by immunofluorescence microscopy. The microfilament-associated proteins actin, alpha-actinin, talin, and ezrin were localized with adherent enteropathogenic E. coli, whereas tropomyosin, ...

journal_title：Infection and immunity

authors： Finlay BB,Rosenshine I,Donnenberg MS,Kaper JB

更新日期：1992-06-01 00:00:00

abstract：:Mice were infected with Chlamydia trachomatis (L2/434) and at various intervals after infection their lymphoid cells were tested directly for cytotoxic activity against Chlamydia-infected L929 cells. In a modified cell-mediated lympholysis assay, splenic, lymph node, and peritoneal exudate cells did not significantly ...

journal_title：Infection and immunity

authors： Pavia CS,Schachter J

更新日期：1983-03-01 00:00:00

abstract：:Francisella tularensis is the causative agent of zoonotic tularemia, a severe pneumonia in humans, and Francisella novicida causes a similarly severe tularemia in mice upon inhalation. The correlates of protective immunity, as well as the virulence mechanisms of this deadly pathogen, are not well understood. In the pr...

journal_title：Infection and immunity

authors： Sharma J,Li Q,Mishra BB,Georges MJ,Teale JM

更新日期：2009-10-01 00:00:00

abstract：:Escherichia coli strains that cause nonbloody diarrhea in infants are known to present three distinct patterns of adherence to epithelial cells, namely, localized (LA), diffuse (DA), and aggregative (AA) adherence. Strains with LA (typical Enteropathogenic Escherichia coli [EPEC]) are well recognized as a cause of sec...

journal_title：Infection and immunity

authors： Scaletsky IC,Pedroso MZ,Oliva CA,Carvalho RL,Morais MB,Fagundes-Neto U

更新日期：1999-07-01 00:00:00

abstract：:Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that other mechanisms of vir...

journal_title：Infection and immunity

authors： McClelland EE,Perrine WT,Potts WK,Casadevall A

更新日期：2005-10-01 00:00:00

abstract：:Murine monoclonal antibodies were generated against streptolysin O. One out of 10 tested immunoglobulin clones exhibited strong neutralizing activity; in solution, the presence of approximately two to four antibody molecules per toxin monomer effected 50% neutralization of hemolytic toxin activity. An enzyme-linked im...

journal_title：Infection and immunity

authors： Hugo F,Reichwein J,Arvand M,Krämer S,Bhakdi S

更新日期：1986-12-01 00:00:00

abstract：:OKM5 antigen and thrombospondin are currently under investigation as potential receptors on the surface of human monocytes, endothelial cells, and melanomas responsible for the cytoadherence of Plasmodium falciparum-infected erythrocytes. We have studies the binding capacity of six human melanoma cell lines and relate...

journal_title：Infection and immunity

authors： Panton LJ,Leech JH,Miller LH,Howard RJ

更新日期：1987-11-01 00:00:00

abstract：:The effects of passive administration of neutralizing monoclonal antibodies (MAB) to respiratory syncytial virus glycoproteins (GP90 and VP70) was evaluated in cotton rats challenged with respiratory syncytial virus. Animals injected with MAB to VP70 had lower mean viral titers in lung tissues than did controls (log10...

journal_title：Infection and immunity

authors： Walsh EE,Schlesinger JJ,Brandriss MW

更新日期：1984-02-01 00:00:00

abstract：:In evolving to an obligate intracellular niche, Chlamydia has streamlined its genome by eliminating superfluous genes as it relies on the host cell for a variety of nutritional needs like amino acids. However, Chlamydia can experience amino acid starvation when the human host cell in which the bacteria reside is expos...

journal_title：Infection and immunity

authors： Ouellette SP,Rueden KJ,Rucks EA

更新日期：2016-08-19 00:00:00

abstract：:Group A streptococci (GAS) are highly prevalent human pathogens whose primary ecological niche is the superficial epithelial layers of the throat and/or skin. Many GAS strains with a strong tendency to cause pharyngitis are distinct from strains that tend to cause impetigo; thus, genetic differences between them may c...

journal_title：Infection and immunity

authors： Rouchon CN,Ly AT,Noto JP,Luo F,Lizano S,Bessen DE

更新日期：2017-10-18 00:00:00

abstract：:Cells of the marine fish pathogen Vibrio anguillarum 775 harboring a plasmid associated with virulence can grow unaffected in the presence of iron-binding compounds such as transferrin. In contrast, the growth of isogenic plasmidless derivatives is inhibited by the presence of iron chelators. Radioactive from (55Fe3+)...

journal_title：Infection and immunity

authors： Crosa JH,Hodges LL

更新日期：1981-01-01 00:00:00

abstract：:A murine monoclonal antibody was raised against the B95-8 strain of Epstein-Barr virus (EBV), which was isolated from a case of mononucleosis after blood transfusion (Hoffman et al. Proc. Natl. Acad. Sci. U.S.A. 77:2979, 1980). We provide evidence that neutralization of immortalization by this monoclonal antibody is v...

journal_title：Infection and immunity

authors： Miller G,Heston L,Hoffman G

更新日期：1982-09-01 00:00:00

abstract：:Tetanus neurotoxin (TeNT) and botulinum neurotoxin (BoNT) are clostridial neurotoxins (CNTs) responsible for the paralytic diseases tetanus and botulism, respectively. CNTs are AB toxins with an N-terminal zinc-metalloprotease light chain that is linked by a disulfide bond to a C-terminal heavy chain that includes a t...

journal_title：Infection and immunity

authors： Blum FC,Przedpelski A,Tepp WH,Johnson EA,Barbieri JT

更新日期：2014-02-01 00:00:00

abstract：:The adherence of Plasmodium falciparum-infected red blood cells (IRBCs) in the human placenta is mediated by chondroitin-4-sulfate (C4S). Although IRBC binding to C4S has been unequivocally established, the adherence characteristics of IRBCs at different stages of parasite development and through successive parasite g...

journal_title：Infection and immunity

authors： Madhunapantula SV,Achur RN,Gowda DC

更新日期：2007-09-01 00:00:00

abstract：:Thirty percent of Streptococcus pneumoniae isolates contain pilus islet 1, coding for a pilus composed of the backbone subunit RrgB and two ancillary proteins, RrgA and RrgC. RrgA is the major determinant of in vitro adhesion associated with pilus 1, is protective in vivo in mouse models, and exists in two variants (c...

journal_title：Infection and immunity

authors： Moschioni M,Emolo C,Biagini M,Maccari S,Pansegrau W,Donati C,Hilleringmann M,Ferlenghi I,Ruggiero P,Sinisi A,Pizza M,Norais N,Barocchi MA,Masignani V

更新日期：2010-12-01 00:00:00

abstract：:Insertional inactivation of the Streptococcus mutans spaP gene was used to construct an isogenic mutant (834) of strain NG8 (serotype c) which lacked the major cell surface-associated protein referred to as P1 (15). Results of several studies suggest that P1 is involved in the adherence of S. mutans to saliva-coated a...

journal_title：Infection and immunity

authors： Bowen WH,Schilling K,Giertsen E,Pearson S,Lee SF,Bleiweis A,Beeman D

更新日期：1991-12-01 00:00:00

abstract：:Mononuclear phagocytes provide the major habitat of intracellular bacteria, including Mycobacterium tuberculosis and Mycobacterium bovis. The capacity of B-cell stimulatory factor 2 (interleukin-6 [IL-6]) to activate tuberculostatic functions was investigated by using murine bone marrow-derived macrophages (BMM phi). ...

journal_title：Infection and immunity

authors： Flesch IE,Kaufmann SH

更新日期：1990-01-01 00:00:00

abstract：:Citrate is a ubiquitous compound and can be utilized by many bacterial species, including enteric pathogens, as a carbon and energy source. Genes involved in citrate utilization have been extensively studied in some enteric bacteria, such as Klebsiella pneumoniae; however, their role in pathogenesis is still not clear...

journal_title：Infection and immunity

authors： Liu M,Hao G,Li Z,Zhou Y,Garcia-Sillas R,Li J,Wang H,Kan B,Zhu J

更新日期：2019-02-21 00:00:00

abstract：:Factors which control the levels of catalase within yeast cells of Histoplasma capsulatum were studied. Only a small fraction of the total catalase activity could be detected in whole cells. The bulk of the activity was revealed in cell-free extracts or in cells permeabilized with acetone. The formation of the enzyme ...

journal_title：Infection and immunity

authors： Howard DH

更新日期：1983-03-01 00:00:00

abstract：:Treponema hyodysenteriae was shown to attach to mouse peritoneal cells in the absence of serum opsonins in vitro. If serotype-specific antiserum from pigs was added to the media and treponemes of that corresponding serotype were employed in the assay, the amount of attachment increased an average of 3.7 times that of ...

journal_title：Infection and immunity

authors： Nuessen ME,Joens LA

更新日期：1982-12-01 00:00:00