Outer membrane proteins induced under conditions of iron limitation in the marine fish pathogen Vibrio anguillarum 775.

abstract：:Although excystation is crucial to the initiation of infection by Giardia lamblia, little is known about the regulation of this important process. We have been able to reliably induce excystation in vitro by mimicking cyst passage through the stomach and upper small intestine by the exposure of in vitro-derived cysts ...

journal_title：Infection and immunity

authors： Meng TC,Hetsko ML,Gillin FD

更新日期：1996-06-01 00:00:00

abstract：:The response to reinfection with Ethiopian Leishmania donovani was evaluated in genetically determined noncure (H-2d) B10.D2 mice that are able to resolve infection due to sublethal irradiation pretreatment after inoculation with a low parasite dose and in C57BL/10 mice that demonstrate the genetically determined cure...

journal_title：Infection and immunity

authors： Ulczak OM,Ghadirian E,Skamene E,Blackwell JM,Kongshavn PA

更新日期：1989-09-01 00:00:00

abstract：:Previous studies showed that Pseudomonas aeruginosa exotoxin A (PA toxin) catalyzes nicotinamide adenine dinucleotide (NAD)-dependent inhibition of protein synthesis in a rabbit reticulocyte lysate and transfer of radioactivity from [14C]adenine-labeled NAD to a protein having the same molecular weight as elongation f...

journal_title：Infection and immunity

authors： Iglewski BH,Liu PV,Kabat D

更新日期：1977-01-01 00:00:00

abstract：:Lipopolysaccharides (LPSs) of Gram-negative bacteria comprise lipid A, core, and O-polysaccharide (OPS) components. Studies have demonstrated that LPSs isolated from the pathogenic species Burkholderia pseudomallei and Burkholderia mallei and from less-pathogenic species, such as Burkholderia thailandensis, are potent...

journal_title：Infection and immunity

authors： Sengyee S,Yoon SH,West TE,Ernst RK,Chantratita N

更新日期：2019-11-18 00:00:00

abstract：:Q fever has been associated with granulomatous changes in clinical biopsy material obtained from liver and bone marrow. Local reactions to skin testing have been described in previously sensitized humans, but histological studies of such reactions have not been reported. We note that delayed hypersensitivity reactions...

journal_title：Infection and immunity

authors： Ascher MS,Berman MA,Parker D,Turk JL

更新日期：1983-01-01 00:00:00

abstract：:Streptococcus mutans, a major oral pathogen responsible for dental caries formation, possesses a variety of mechanisms for survival in the human oral cavity, where the conditions of the external environment are diverse and in a constant state of flux. The formation of biofilms, survival under conditions of acidic pH, ...

journal_title：Infection and immunity

authors： Chong P,Drake L,Biswas I

更新日期：2008-07-01 00:00:00

abstract：:Yersinia pseudotuberculosis inv mutant strains cured of the virulence plasmid exhibit thermoinducible adhesion to cultured mammalian cells. To identify the genes responsible for this phenotype, Y. pseudotuberculosis homologs of the Y. enterocolitica ail and the Y. pestis psa loci were identified. Mutations in the Y. p...

journal_title：Infection and immunity

authors： Yang Y,Merriam JJ,Mueller JP,Isberg RR

更新日期：1996-07-01 00:00:00

abstract：:Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in humans and has potential for use as a biological weapon. The genetic basis of the F. tularensis virulence is poorly understood. This study screened a total of 3,936 transposon mutants of the live vaccine strain for infection ...

journal_title：Infection and immunity

authors： Su J,Yang J,Zhao D,Kawula TH,Banas JA,Zhang JR

更新日期：2007-06-01 00:00:00

abstract：:Mouse peritoneal macrophages were successfully infected with two strains of Junin virus producing high titers with no apparent cell damage. Infected cultures survived longer than noninfected cultures. The pattern of virus release suggested a persistent infection. Virus replication was delayed in macrophages from mice ...

journal_title：Infection and immunity

authors： González PH,Lampuri JS,Coto CE,Laguens RP

更新日期：1982-01-01 00:00:00

abstract：:Infection with Giardia duodenalis is one of the most common causes of diarrheal disease in the world. While numerous studies have identified important contributions of adaptive immune responses to parasite control, much less work has examined innate immunity and its connections to the adaptive response during this inf...

journal_title：Infection and immunity

authors： Li E,Tako EA,Singer SM

更新日期：2016-03-24 00:00:00

abstract：:Polyprotein allergens are a family of structurally homologous molecules from parasitic nematodes which induce specific immunoglobulin E in infected individuals. We show here that both H-2 and non-H-2 factors determine the ability of mice to generate T- and B-cell responses to the filarial polyprotein allergen (Brugia ...

journal_title：Infection and immunity

authors： Allen JE,Lawrence RA,Maizels RM

更新日期：1995-08-01 00:00:00

abstract：:The adherence of invasive Escherichia coli strains 444-3 and 469-3 to human erythrocytes and to cultured HeLa and HEp-2 cells has been examined by electron microscopy. Bacteria elaborating type 1 fimbriae, glycocalyces , and nonfimbrial mannose-resistant hemagglutinins specific for human erythrocytes were identified i...

journal_title：Infection and immunity

authors： Knutton S,Williams PH,Lloyd DR,Candy DC,McNeish AS

更新日期：1984-06-01 00:00:00

abstract：:Murine embryo fibroblasts (MEF) were found to secrete tumor necrosis factor (TNF) in response to stimulation with endotoxin. Endotoxin-induced TNF production by MEF was inhibited by cycloheximide. However, reversal of the effect of this inhibitor on protein synthesis results in TNF being secreted in amounts equivalent...

journal_title：Infection and immunity

authors： Havell EA,Rogerson BJ

更新日期：1993-05-01 00:00:00

abstract：:Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that other mechanisms of vir...

journal_title：Infection and immunity

authors： McClelland EE,Perrine WT,Potts WK,Casadevall A

更新日期：2005-10-01 00:00:00

abstract：:Immunity to Mycobacterium tuberculosis is dependent upon the generation of a protective gamma interferon (IFN-gamma)-producing T-cell response. Recent studies have suggested that interleukin-6 (IL-6) is required for the induction of a protective T-cell response and that IL-4 may suppress the induction of IFN-gamma. To...

journal_title：Infection and immunity

authors： Saunders BM,Frank AA,Orme IM,Cooper AM

更新日期：2000-06-01 00:00:00

abstract：:In the presence of temporary obstruction (20 h), ascending Escherichia coli urinary infection leads to irreversible acute exudative pyelonephritis (AEP) in rats. The purpose of the present study was to investigate the early inflammatory events which take place in response to the presence of bacteria in the kidney pare...

journal_title：Infection and immunity

authors： Glauser MP,Francioli PB,Bille J,Bonard M,Meylan P

更新日期：1983-05-01 00:00:00

abstract：:Following intranasal inoculation, Vibrio cholerae KFV101 (DeltactxAB DeltahapA DeltahlyA DeltartxA) colonizes and stimulates tumor necrosis factor alpha and interleukin 1beta (IL-1beta) in mice, similar to what occurs with isogenic strain P4 (DeltactxAB), but is less virulent and stimulates reduced levels of IL-6, dem...

journal_title：Infection and immunity

authors： Haines GK 3rd,Sayed BA,Rohrer MS,Olivier V,Satchell KJ

更新日期：2005-09-01 00:00:00

abstract：:Toxoplasma gondii is a protozoan parasite that is able to penetrate human monocytes by either passive uptake during phagocytosis or active penetration. It is expected that immunoglobulin G (IgG) opsonization will target the parasite to macrophage Fc gamma receptors for phagocytic processing and subsequent degradation....

journal_title：Infection and immunity

authors： Fadul CE,Channon JY,Kasper LH

更新日期：1995-11-01 00:00:00

abstract：:Neisseria gonorrhoeae releases peptidoglycan fragments during growth, and these molecules induce an inflammatory response in the human host. The proinflammatory molecules include peptidoglycan monomers, peptidoglycan dimers, and free peptides. These molecules can be released by the actions of lytic transglycosylases o...

journal_title：Infection and immunity

authors： Schaub RE,Perez-Medina KM,Hackett KT,Garcia DL,Dillard JP

更新日期：2019-01-24 00:00:00

abstract：:Schistosoma mansoni eggs produced by adult worms in the mesenteric vasculature become trapped in the liver, where they induce granulomatous lesions and strong immune responses. Infected individuals suffer from intestinal schistosomiasis (INT) in 90% of cases, whereas the remaining 10% present with severe hepatosplenic...

journal_title：Infection and immunity

authors： Manivannan B,Rawson P,Jordan TW,Secor WE,La Flamme AC

更新日期：2010-02-01 00:00:00

abstract：:Brucella abortus injected into CBA mice replicated primarily in the spleen and liver, reaching a peak bacterial count in both organs about 7 days postinfection. The organism was eliminated from the liver but declined to a chronic phase in the spleen. The infection caused hepatosplenomegaly. An influx of macrophages in...

journal_title：Infection and immunity

authors： Doyle AG,Halliday WJ,Barnett CJ,Dunn TL,Hume DA

更新日期：1992-04-01 00:00:00

abstract：:In Vibrio cholerae, the transmembrane DNA binding proteins, ToxR and TcpP, activate expression of the regulatory gene toxT in response to specific environmental signals. The resulting enhanced level of ToxT leads to a coordinated increase in the production of a subset of virulence factors, including cholera toxin (CT)...

journal_title：Infection and immunity

authors： Krishnan HH,Ghosh A,Paul K,Chowdhury R

更新日期：2004-07-01 00:00:00

abstract：:Cytomegalovirus (CMV) infections are common in renal transplant recipients. We studied 23 recipients prospectively to determine whether infections by other herpes-group and non-herpes-group viruses were also present. Sera, obtained at the time of surgery and periodically thereafter, were tested for antibody to CMV, he...

journal_title：Infection and immunity

authors： Armstrong JA,Evans AS,Rao N,Ho M

更新日期：1976-10-01 00:00:00

abstract：:Streptococcus suis is one of the most important pathogens affecting the swine industry and is also an emerging zoonotic agent for humans. Two-component signaling systems (TCSs) play important roles in the adaptation of pathogenic bacteria to host environments. In this study, we identified a novel TCS, named TCS09HKRR,...

journal_title：Infection and immunity

authors： Zhong X,Zhang Y,Zhu Y,Dong W,Ma J,Pan Z,Yao H

更新日期：2019-08-21 00:00:00

abstract：:Nontypeable Haemophilus influenzae (NTHI) has four loci, lic-1 to lic-3 and lgtC, that generate phase-variable lipooligosaccharide (LOS) structures. lic-1, which is required for the expression of phosphorylcholine (ChoP), is the best characterized and is associated with an enhanced ability of H. influenzae to persist ...

journal_title：Infection and immunity

authors： Tong HH,Blue LE,James MA,Chen YP,DeMaria TF

更新日期：2000-08-01 00:00:00

abstract：:A canine distemper virus (CDV), DESIGNATED R252, originally recovered from a dog with demyelinating encephalomyelitis was shown to reproduce this disease in gnotobiotic dogs with a high incidence as compared to other CDV strains, which produced an acute fatal infection. In this investigation, R252 was propagated for t...

journal_title：Infection and immunity

authors： Confer AW,Kahn DE,Koestner A,Krakowka S

更新日期：1975-04-01 00:00:00

abstract：:Strain TG is a plasmidless exfoliative toxin (ET) producer. Strain ER201 contains a plasmid, whose loss had no apparent effect on ET production. The plasmid of ER201 was almost identical in size to the plasmid from strain UT0007, which carries an ET determinant. ...

journal_title：Infection and immunity

authors： Rosenblum ED,Tyrone S

更新日期：1976-11-01 00:00:00

abstract：:Galactomannan (GM) extracted from mycelia of Aspergillus fumigatus with cold dilute alkali reacted with antiserum specific for an antigen that circulated in invasive aspergillosis in rabbits and humans. The GM was purified by its affinity for concanavalin A and was separated from a nonantigenic glucan by gel permeatio...

journal_title：Infection and immunity

authors： Reiss E,Lehmann PF

更新日期：1979-07-01 00:00:00

abstract：:Increased protection against a virulent challenge with Mycobacterium tuberculosis is induced mainly by a previous immunization with living avirulent mycobacteria, usually Mycobacterium bovis BCG. Only a transient and marginal protection is obtained after immunization with bacterial extracts or dead bacteria. Both livi...

journal_title：Infection and immunity

authors： Romain F,Laqueyrerie A,Militzer P,Pescher P,Chavarot P,Lagranderie M,Auregan G,Gheorghiu M,Marchal G

更新日期：1993-02-01 00:00:00

abstract：:Initiation of a gonococcal infection involves attachment of Neisseria gonorrhoeae to the plasma membrane of an epithelial cell in the mucosal epithelium and its internalization, transepithelial trafficking, and exocytosis from the basal membrane. Piliation and expression of certain Opa proteins and the immunoglobulin ...

journal_title：Infection and immunity

authors： Hopper S,Wilbur JS,Vasquez BL,Larson J,Clary S,Mehr IJ,Seifert HS,So M

更新日期：2000-02-01 00:00:00