Relationship of virulence factor expression to evolved virulence in mouse-passaged Cryptococcus neoformans lines.

abstract：:Serological tests used in current brucellosis eradication schemes, such as bacterial tube agglutination, do not readily distinguish between infected animals and those immunized with strain 19 or 45/20 Brucella abortus vaccines. In this study, sera from naturally infected cattle were used to identify serologically impo...

journal_title：Infection and immunity

authors： Raybould TJ,Chantler S

更新日期：1980-08-01 00:00:00

abstract：:The plasma level of the chemokine CCL3 is elevated in patients with chronic severe schistosomiasis mansoni. We have previously shown that CCL3(-/-) mice with experimental infection showed diminished pathology and worm burden compared to those of wild-type (WT) mice. To elucidate further the role of CC chemokines durin...

journal_title：Infection and immunity

authors： Souza AL,Souza PR,Pereira CA,Fernandes A,Guabiraba R,Russo RC,Vieira LQ,Corrêa A Jr,Teixeira MM,Negrão-Corrêa D

更新日期：2011-04-01 00:00:00

abstract：:In 2001, a bioterrorism attack involving Bacillus anthracis spore-laced letters resulted in 22 cases of inhalation anthrax, with five fatalities. This incident identified gaps in our health care system and precipitated a renewed interest in identifying both therapeutics and rapid diagnostic assays. To address those ga...

journal_title：Infection and immunity

authors： Rossi CA,Ulrich M,Norris S,Reed DS,Pitt LM,Leffel EK

更新日期：2008-12-01 00:00:00

abstract：:In this study we found that serum inhibitory activity against Blastomyces dermatitidis was principally mediated by albumin. This was confirmed in experiments using albumin from several mammalian species. Analbuminemic rat serum did not inhibit B. dermatitidis growth in vivo; however, the addition of albumin restored i...

journal_title：Infection and immunity

authors： Giles S,Czuprynski C

更新日期：2003-11-01 00:00:00

abstract：:Fifty Borellia burgdorferi strains isolated from humans and ticks in Europe and the United States were analyzed by multilocus enzyme electrophoresis. Eleven genetic loci were characterized on the basis of the electrophoretic mobilities of their products. Ten loci were polymorphic. The average number of alleles per loc...

journal_title：Infection and immunity

authors： Boerlin P,Peter O,Bretz AG,Postic D,Baranton G,Piffaretti JC

更新日期：1992-04-01 00:00:00

abstract：:Campylobacter jejuni is a leading cause of infectious diarrhea throughout the world. In addition, there is growing evidence that Guillain-Barré syndrome, an inflammatory demyelinating disease of the peripheral nervous system, is frequently preceded by C. jejuni infection. In the present study, the hrcA-grpE-dnaK gene ...

journal_title：Infection and immunity

authors： Thies FL,Karch H,Hartung HP,Giegerich G

更新日期：1999-03-01 00:00:00

abstract：:The DNA oligomer 5'-d(TGCGGCCTCTCAGTCCCGCACTTTCATCTTCC)-3' specifically recognizes Haemophilus influenzae 16S rRNA. We report here the use of this oligonucleotide, with a fluorescein label tagged on its 5' end, as a probe for the in situ detection of nonencapsulated nontypeable H. influenzae in sections of adenoid tis...

journal_title：Infection and immunity

authors： Forsgren J,Samuelson A,Ahlin A,Jonasson J,Rynnel-Dagöö B,Lindberg A

更新日期：1994-02-01 00:00:00

abstract：:Rats kept under germfree conditions showed lower specific lysosomal enzyme activities in liver endothelial cells, but not in Kupffer cells. ...

journal_title：Infection and immunity

authors： Knook DL,Barkway C,Sleyster EC

更新日期：1981-08-01 00:00:00

abstract：:Actinomyces naeslundii and Streptococcus gordonii, oral bacteria that possess Gal/GalNAc- and sialic acid-reactive lectins, respectively, were adherent to immobilized secretory immunoglobulin A (IgA) and two IgA1 myeloma proteins but not to two IgA2 myeloma proteins. Apparently, O-linked oligosaccharides at the hinge ...

journal_title：Infection and immunity

authors： Ruhl S,Sandberg AL,Cole MF,Cisar JO

更新日期：1996-12-01 00:00:00

abstract：:The Fcγ receptor IIIb (FcγRIIIb) is a low-affinity receptor of IgG and is essential in neutrophil-mediated effector functions. Different allelic forms of FcγRIIIb carrying human neutrophil antigen (HNA-1a, -1b, -1c, and -1d) have been identified. Here, we have generated stable transfected HEK293 cell lines expressing ...

journal_title：Infection and immunity

authors： Simtong P,Romphruk AV,Traum A,Burg-Roderfeld M,Bein G,Jakubowski K,Dominik A,Theisen M,Kana IH,Sachs UJ,Santoso S

更新日期：2018-07-23 00:00:00

abstract：:Vibrio cholerae is a monoflagellated gram-negative bacterium that causes the severe diarrheal disease cholera. In contrast to Salmonella enterica serovar Typhimurium infection, which is accompanied by both acute diarrhea and high-level inflammation, V. cholerae infection is largely noninflammatory in human hosts. Bact...

journal_title：Infection and immunity

authors： Yoon SS,Mekalanos JJ

更新日期：2008-03-01 00:00:00

abstract：:Blood mononuclear cells (lymphocytes and monocytes) were isolated from infected calves during in vivo control of acute anaplasmosis and cultured with Anaplasma marginale organisms. Supernatants from the cultures reduced the proportion of erythrocytes containing viable A. marginale in vitro, indicating that an antibody...

journal_title：Infection and immunity

authors： Wyatt CR,Davis WC,Knowles DP,Goff WL,Palmer GH,McGuire TC

更新日期：1996-11-01 00:00:00

abstract：:Escherichia coli is the most common cause of urinary tract infection. Elevated blood and urine interleukin-6 (IL-6) levels have been shown in inflammatory urinary tract diseases. The role of IL-6 in mediating the urodynamic dysfunction in response to E. coli-induced urinary tract infection has not yet been fully eluci...

journal_title：Infection and immunity

authors： Weng TI,Wu HY,Lin PY,Liu SH

更新日期：2009-08-01 00:00:00

abstract：:Subtilase cytotoxin (SubAB) is a recently identified AB5 subunit toxin produced by Shiga-toxigenic Escherichia coli. The A subunit is thought to be a subtilase-like, serine protease, whereas the B subunit binds to the toxin receptor on the cell surface. We cloned the genes from a clinical isolate; the toxin was produc...

journal_title：Infection and immunity

authors： Morinaga N,Yahiro K,Matsuura G,Watanabe M,Nomura F,Moss J,Noda M

更新日期：2007-01-01 00:00:00

abstract：:Vaccine candidates against Shigella dysenteriae type 1, which is associated with the most severe cases of bacillary dysentery, were constructed. The rfp and rfb gene clusters, which code for S. dysenteriae 1 O antigen biosynthesis, were randomly integrated into either the chromosome or the virulence plasmid of the rou...

journal_title：Infection and immunity

authors： Klee SR,Tzschaschel BD,Fält I,Kärnell A,Lindberg AA,Timmis KN,Guzmán CA

更新日期：1997-06-01 00:00:00

abstract：:Here we describe a protocol for purifying Borrelia burgdorferi from feeding ticks by velocity centrifugation and Percoll density gradient centrifugation. The purified spirochetes were motile and 10- to 20-fold purer than the bacteria in crude tick homogenates. The purified bacteria were present in sufficient quantity ...

journal_title：Infection and immunity

authors： Rathinavelu S,de Silva AM

更新日期：2001-06-01 00:00:00

abstract：:Three parameters of rotavirus infection, i.e., clinical disease, viral antigen in infected intestines, and infectious virus in feces, were assessed in infant mice nursed by mothers with or without preexisting rotavirus antibody. Diarrhea was the only consistent sign of clinical disease, and its course followed that of...

journal_title：Infection and immunity

authors： Little LM,Shadduck JA

更新日期：1982-11-01 00:00:00

abstract：:Previous studies have suggested that the Pseudomonas aeruginosa PAK pilus adhesin moiety resides in an epithelial cell-binding domain located in the C-terminal region of the PAK pilin structural protein. Synthetic peptides Ac17red (a synthetic peptide with a sequence identical to that of PAK pilin residues 128 to 144,...

journal_title：Infection and immunity

authors： Irvin RT,Doig P,Lee KK,Sastry PA,Paranchych W,Todd T,Hodges RS

更新日期：1989-12-01 00:00:00

abstract：:Tuberculosis (TB) remains an enormous global health problem, and a new vaccine against TB more potent than the current inadequate vaccine, Mycobacterium bovis BCG, is urgently needed. We describe a recombinant BCG vaccine (rBCG30) expressing and secreting the 30-kDa major secretory protein of Mycobacterium tuberculosi...

journal_title：Infection and immunity

authors： Horwitz MA,Harth G

更新日期：2003-04-01 00:00:00

abstract：:In evolving to an obligate intracellular niche, Chlamydia has streamlined its genome by eliminating superfluous genes as it relies on the host cell for a variety of nutritional needs like amino acids. However, Chlamydia can experience amino acid starvation when the human host cell in which the bacteria reside is expos...

journal_title：Infection and immunity

authors： Ouellette SP,Rueden KJ,Rucks EA

更新日期：2016-08-19 00:00:00

abstract：:The level of type-specific antigen (that covalently associated with the cell wall peptidoglycan and that released extracellularly) synthesized by virulent and avirulent strains of type III group B streptococci was quantitated and compared. Additionally, the effect of the physiological age of the cells and the influenc...

journal_title：Infection and immunity

authors： Yeung MK,Mattingly SJ

更新日期：1984-05-01 00:00:00

abstract：:An enhanced memory response, as shown by increased titers of specific immunoglobulin A (IgA), was seen in intestinal secretions from isolated Thiry-Vella loops in rabbits primed orally with live, locally invasive Shigella sp. X16 and challenged 60 days later with a single oral dose of the same antigen. Heat-killed shi...

journal_title：Infection and immunity

authors： Keren DF,McDonald RA,Scott PJ,Rosner AM,Strubel E

更新日期：1985-01-01 00:00:00

abstract：:The within-host dynamics of an infection with the malaria parasite Plasmodium falciparum are the result of a complex interplay between the host immune system and parasite. Continual variation of the P. falciparum erythrocyte membrane protein (PfEMP1) antigens displayed on the surface of infected red blood cells enable...

journal_title：Infection and immunity

authors： Klein EY,Graham AL,Llinás M,Levin S

更新日期：2014-01-01 00:00:00

abstract：:We identified a T-cell determinant of the 35-kDa antigen of Mycobacterium leprae which is discriminatory against cross-sensitization by its closely related homologue in Mycobacterium avium. From synthetic peptides covering the entire sequence, those with the highest affinity and permissive binding to purified HLA-DR m...

journal_title：Infection and immunity

authors： Wilkinson RJ,Wilkinson KA,Jurcevic S,Hills A,Sinha S,Sengupta U,Lockwood DN,Katoch K,Altman D,Ivanyi J

更新日期：1999-03-01 00:00:00

abstract：:Heart and muscle tissues appear to be specific target organs for the in vivo inhibition of protein synthesis by diphtheria toxin. ...

journal_title：Infection and immunity

authors： Bowman CG,Imhoff JG,Bonventre PF

更新日期：1970-11-01 00:00:00

abstract：:We have investigated the ability of two species of streptococci isolated from the human oral cavity (Streptococcus mutans NCTC 10449 and Streptococcus sobrinus SL-1) to metabolize N-acetylglucosamine (GlcNAc), a naturally occurring amino sugar present in saliva and human glycoproteins, when provided as the sole fermen...

journal_title：Infection and immunity

authors： Homer KA,Patel R,Beighton D

更新日期：1993-01-01 00:00:00

abstract：:Candida albicans is a major opportunistic pathogen in immunocompromised patients. Production of proinflammatory cytokines by host cells in response to C. albicans plays a critical role in the activation of immune cells and final clearance of the organism. Invasion of host cells and tissues is considered one of the vir...

journal_title：Infection and immunity

authors： Villar CC,Kashleva H,Mitchell AP,Dongari-Bagtzoglou A

更新日期：2005-08-01 00:00:00

abstract：:Reverse transcriptase PCR analyses have demonstrated that open reading frames (ORFs) PM0298, PM0299, and PM0300 of the animal pathogen Pasteurella multocida constitute a single transcriptional unit. By cloning and overexpression studies in Escherichia coli cells, the product of ORF PM0300 was shown to bind hemoglobin ...

journal_title：Infection and immunity

authors： Bosch M,Garrido ME,Llagostera M,Pérez De Rozas AM,Badiola I,Barbé J

更新日期：2002-11-01 00:00:00

abstract：:Cysteine proteases, including Arg-gingipain of Porphyromonas gingivalis, have been implicated as important virulence factors in periodontal diseases. These enzymes are also involved in the hemagglutinating activity of the organisms. In order to determine the role of proteases in the colonization of the gingival margin...

journal_title：Infection and immunity

authors： Tokuda M,Duncan M,Cho MI,Kuramitsu HK

更新日期：1996-10-01 00:00:00

abstract：:Cholera enterotoxin and the related heat-labile enterotoxins of Escherichia coli enter their target cells through noncoated vesicles, but how the toxins are processed intracellularly and how they get to their targeted enzyme, adenylate cyclase, remain to be defined. Brefeldin A, an inhibitor of the trans-Golgi network...

journal_title：Infection and immunity

authors： Donta ST,Beristain S,Tomicic TK

更新日期：1993-08-01 00:00:00