Uropathogenic Escherichia coli-induced inflammation alters mouse urinary bladder contraction via an interleukin-6-activated inducible nitric oxide synthase-related pathway.

abstract：:El Tor and non-O1 strains of Vibrio cholerae were analyzed to determine whether synthesis of secreted hemolysin was influenced by the concentration of iron in the medium. Synthesis of hemolysin was found to be iron regulated in both El Tor and non-O1 isolates. Increased levels of hemolytic activity were detected in su...

journal_title：Infection and immunity

authors： Stoebner JA,Payne SM

更新日期：1988-11-01 00:00:00

abstract：:In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phe...

journal_title：Infection and immunity

authors： Rivas-Santiago B,Serrano CJ,Enciso-Moreno JA

更新日期：2009-11-01 00:00:00

abstract：:Studies were performed to determine the optimal sites for primary isolation of Mycoplasma pulmonis from the respiratory system of laboratory rats. In a preliminary study, a group of 42 rats was cultured for respiratory M. pulmonis at several sites. Tracheal washes yielded the highest number of positive cultures (61.9%...

journal_title：Infection and immunity

authors： Lentsch RH,Wagner JE,Owens DR

更新日期：1979-11-01 00:00:00

abstract：:Strain superinfection occurs when a second pathogen strain infects a host already carrying a primary strain. Anaplasma marginale superinfection occurs when the second strain carries a variant repertoire different from that of the primary strain, and the epidemiologic consequences depend on the relative efficiencies of...

journal_title：Infection and immunity

authors： Galletti MF,Ueti MW,Knowles DP Jr,Brayton KA,Palmer GH

更新日期：2009-04-01 00:00:00

abstract：:Previous studies have demonstrated that the Moraxella catarrhalis surface antigen UspA1 is an adhesin for Chang human conjunctival cells. The present report demonstrates that lack of UspA1 expression does not affect the adherence of strain O35E to A549 human lung cells or primary cultures of human middle ear epithelia...

journal_title：Infection and immunity

authors： Holm MM,Vanlerberg SL,Sledjeski DD,Lafontaine ER

更新日期：2003-09-01 00:00:00

abstract：:Bordetella bronchiseptica is a Gram-negative bacterium that infects and causes disease in a wide variety of animals. B. bronchiseptica also infects humans, thereby demonstrating zoonotic transmission. An extensive characterization of human B. bronchiseptica isolates is needed to better understand the distinct genetic ...

journal_title：Infection and immunity

authors： Sukumar N,Nicholson TL,Conover MS,Ganguly T,Deora R

更新日期：2014-04-01 00:00:00

abstract：:Staphylococcus aureus can produce a wide variety of exotoxins, including toxic shock syndrome toxin 1 (TSST-1), staphylococcal enterotoxins, and staphylococcal enterotoxin-like toxins. These toxins share superantigenic activity. To investigate the beta chain (Vbeta) specificities of each of these toxins, TSST-1 and al...

journal_title：Infection and immunity

authors： Thomas D,Dauwalder O,Brun V,Badiou C,Ferry T,Etienne J,Vandenesch F,Lina G

更新日期：2009-05-01 00:00:00

abstract：:Factors which control the levels of catalase within yeast cells of Histoplasma capsulatum were studied. Only a small fraction of the total catalase activity could be detected in whole cells. The bulk of the activity was revealed in cell-free extracts or in cells permeabilized with acetone. The formation of the enzyme ...

journal_title：Infection and immunity

authors： Howard DH

更新日期：1983-03-01 00:00:00

abstract：:During the recent bioterrorism-related outbreaks, inhalational anthrax had a 45% mortality in spite of appropriate antimicrobial therapy, underscoring the need for better adjuvant therapies. The variable latency between exposure and development of disease suggests an important role for the host's innate immune respons...

journal_title：Infection and immunity

authors： Gold JA,Hoshino Y,Hoshino S,Jones MB,Nolan A,Weiden MD

更新日期：2004-03-01 00:00:00

abstract：:Bacterial superantigens (SAgs) have been implicated in inflammatory disease, and SAg-treated mice have increased jejunal T cells. Here we show that T84 cells (a human epithelial cell line) display increased MCP-1 and RANTES mRNA expression and protein production in response to conditioned medium from Staphylococcus au...

journal_title：Infection and immunity

authors： Jedrzkiewicz S,Kataeva G,Hogaboam CM,Kunkel SL,Strieter RM,McKay DM

更新日期：1999-11-01 00:00:00

abstract：:Chromatographic analysis, coupled to mass spectrometry with a high-resolution mass spectrometer, of materials isolated from skin lesions of patients with lepromatous leprosy allows the recognition of characteristic mycobacterial products, mycolic acids. This finding indicates that the "noncultivable" bacteria responsi...

journal_title：Infection and immunity

authors： Etemadi AH,Convit J

更新日期：1974-07-01 00:00:00

abstract：:In Brucella abortus, a gene encoding a major cell envelope protein, omp2, is duplicated within a short segment of the large chromosomal DNA. Although both genes contain open reading frames, encoding proteins of high identity, expression from only one, omp2b, has been detected in laboratory-grown B. abortus. In the pre...

journal_title：Infection and immunity

authors： Marquis H,Ficht TA

更新日期：1993-09-01 00:00:00

abstract：:We have shown previously that Klebsiella pneumoniae receptors for coliphages T3 and T7 also mediate mannose-inhibitable adherence to human epithelial cells and protect bacteria from phagocytosis and intracellular killing by human polymorphonuclear cells. In this paper we analyze the possible role of such mannose-inhib...

journal_title：Infection and immunity

authors： Pruzzo C,Valisena S,Satta G

更新日期：1983-02-01 00:00:00

abstract：:We have investigated the possibility that nitric oxide (NO) synthesis may affect the course of a trypanosome infection via T-cell responses using mice deficient in inducible NO synthase (iNOS). Parasitemia levels increased at the same rate in both iNOS-deficient homozygous and control heterozygous mice, and peak paras...

journal_title：Infection and immunity

authors： Millar AE,Sternberg J,McSharry C,Wei XQ,Liew FY,Turner CM

更新日期：1999-07-01 00:00:00

abstract：:Using the indirect fluorescein-labeled and indirect peroxidase-antiperoxidase-labeled immunohistochemical techniques, and utilizing both antiserum specific for the beta-subunit of choriogonadotropin and antiserum for the total hormone, we have demonstrated the presence of a choriogonadotropin-like immunoreactive mater...

journal_title：Infection and immunity

authors： Acevedo HF,Slifkin M,Pouchet-Melvin GR,Campbell-Acevedo EA

更新日期：1979-06-01 00:00:00

abstract：:Neutrophil collagenase (matrix metalloproteinase 8 [MMP-8]) is an important mediator of tissue destruction in inflammatory diseases. Studies of anaerobic periodontal infections have shown that active MMP-8 in gingival crevicular fluid is associated with the degradation of periodontal tissues in progressive periodontit...

journal_title：Infection and immunity

authors： Romanelli R,Mancini S,Laschinger C,Overall CM,Sodek J,McCulloch CA

更新日期：1999-05-01 00:00:00

abstract：:The porcine immunoglobulins M (IgM), A (IgA), and G (IgG) were isolated and purified and some of the properties of the porcine milk IgA were examined. Monospecific antisera which were prepared against these immunoglobulins in rabbits were then used to absorb a particular class of immunoglobulin from sow serum, colostr...

journal_title：Infection and immunity

authors： Saif LJ,Bohl EH,Gupta RK

更新日期：1972-10-01 00:00:00

abstract：:The Bordetella pertussis BrkA protein protects against the bactericidal activity of complement and antibody; however, some individuals mount an immune response that overcomes this bacterial defense. To further characterize this process, the bactericidal activities of sera from 13 adults with different modes of exposur...

journal_title：Infection and immunity

authors： Weiss AA,Mobberley PS,Fernandez RC,Mink CM

更新日期：1999-03-01 00:00:00

abstract：:There is an emerging paradigm shift from coronary heart disease having a purely hereditary and nutritional causation to possibly having an infectious etiology. Recent epidemiological studies have shown a correlation between periodontal disease and coronary heart disease. However, to date, there is minimal information ...

journal_title：Infection and immunity

authors： Dorn BR,Dunn WA Jr,Progulske-Fox A

更新日期：1999-11-01 00:00:00

abstract：:Malaria toxin causes hypoglycemia and induction of tumor necrosis factor. Extracts of parasitized erythrocytes which were coeluted and copurified with one of the two subtypes of mammalian insulin-mimetic inositolphosphoglycans similarly induced fibroblast proliferation in the absence of serum. In addition, induction o...

journal_title：Infection and immunity

authors： Caro HN,Sheikh NA,Taverne J,Playfair JH,Rademacher TW

更新日期：1996-08-01 00:00:00

abstract：:The presence of soybean meal in the diet of gnotobiotic mice was shown to prevent the establishment of a clostridial strain in the gastrointestinal tract. Soybean meal did not inhibit the growth of Clostridium in vitro, suggesting that the host plays a role in the observed inhibition of bacterial growth. The inhibitor...

journal_title：Infection and immunity

authors： Lhuillery C,Demarne Y,Ducluzeau R,Clara A

更新日期：1982-05-01 00:00:00

abstract：:Once Candida albicans comes in contact with endothelial cells, it induces cellular injury. This endothelial cell injury may be a mechanism by which blood-borne organisms escape from the intravascular compartment and invade the tissue parenchyma during hematogenous infection. We have been investigating the ability of c...

journal_title：Infection and immunity

authors： Fratti RA,Ghannoum MA,Edwards JE Jr,Filler SG

更新日期：1996-11-01 00:00:00

abstract：:In vivo- and in vitro-grown Mycoplasma hyopneumoniae organisms were inoculated onto newborn piglet tracheal organ cultures to provide a model for interaction of this organism with ciliated respiratory epithelium. Ciliostasis and loss of cilia in tracheal rings were induced by M. hyopneumoniae grown in vivo and with lo...

journal_title：Infection and immunity

authors： DeBey MC,Ross RF

更新日期：1994-12-01 00:00:00

abstract：:A concentrated bacterial culture supernatant from the hemolytic Moraxella bovis strain UQV 148NF was used to immunize mice and generate monoclonal antibodies (MAbs). One, MAb G3/D7, neutralized the hemolytic activity of M. bovis and recognized a 94-kDa protein by Western blot analysis in hemolytic M. bovis strains rep...

journal_title：Infection and immunity

authors： Billson FM,Harbour C,Michalski WP,Tennent JM,Egerton JR,Hodgson JL

更新日期：2000-06-01 00:00:00

abstract：:The ApxIIA protein secreted from Actinobacillus pleuropneumoniae is both hemolytic and cytotoxic. However, when the cloned apxII operon is expressed in Escherichia coli, two forms of the ApxIIA protein can be recovered. Toxin which remains intracellular has hemolytic and cytotoxic activities, while toxin that is secre...

journal_title：Infection and immunity

authors： Tu AH,Hausler C,Young R,Struck DK

更新日期：1994-05-01 00:00:00

abstract：:Ribosomal subunits from Mycobacterium smegmatis were analyzed by using sedimentation velocity, sedimentation equilibrium, and acrylamide gel electrophoresis experiments. These s(20.w) values for the subunits are 48.7S and 28.1S. The molecular weight of the 49S subunit is about 1.65 x 10(6), and that of the 28S subunit...

journal_title：Infection and immunity

authors： Loge RV,Hill WE,Baker RE,Larson CL

更新日期：1974-03-01 00:00:00

abstract：:A Gram-negative, filamentous, rod-shaped bacillus which failed to grow in cell-free media was isolated in apparently pure culture from the bronchial scraping and washing of a laboratory rat suffering from chronic respiratory disease by inoculating embryonated chicken eggs via the allantoic route. None of the embryos d...

journal_title：Infection and immunity

authors： Ganaway JR,Spencer TH,Moore TD,Allen AM

更新日期：1985-02-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) glycoprotein gC was purified by affinity chromatography with an immunosorbent column containing monoclonal antibody to HSV-1 gC, and its reactivity with rabbit antisera was measured by enzyme-linked immunosorbent assay and sodium dodecyl sulfate-polyacrylamide gel electrophoretic an...

journal_title：Infection and immunity

authors： Zweig M,Heilman CJ Jr,Bladen SV,Showalter SD,Hampar B

更新日期：1983-08-01 00:00:00

abstract：:Autotransporters of gram-negative bacteria are single-peptide secretion systems that consist of a functional N-terminal alpha-domain ("passenger") fused to a C-terminal beta-domain ("translocator"). How passenger proteins are translocated through the outer membrane has not been resolved, and at present essentially thr...

journal_title：Infection and immunity

authors： Müller D,Benz I,Tapadar D,Buddenborg C,Greune L,Schmidt MA

更新日期：2005-07-01 00:00:00

abstract：:We constructed hha derivatives from both a clinical uropathogenic Escherichia coli isolate (strain FVL4) and a wild E. coli strain causing bovine diarrhea (strain CCB21) and analyzed the effect of the hha allele on the expression of the different virulence factors exhibited by these strains. Expression of hemolysin an...

journal_title：Infection and immunity

authors： Mouriño M,Madrid C,Balsalobre C,Prenafeta A,Muñoa F,Blanco J,Blanco M,Blanco JE,Juarez A

更新日期：1996-07-01 00:00:00