Delayed hypersensitivity reactions provoked by ribosomes from acid-fast bacilli: physical characteristics and immunological aspects of core ribosomal proteins from Mycobacterium smegmatis.

abstract：:Francisella tularensis is a facultative intracellular bacterial pathogen and the causative agent of tularemia. After infection of macrophages, the organism escapes from its phagosome and replicates to high density in the cytosol, but the bacterial factors required for these aspects of virulence are incompletely define...

journal_title：Infection and immunity

authors： Long ME,Lindemann SR,Rasmussen JA,Jones BD,Allen LA

更新日期：2013-03-01 00:00:00

abstract：:The nucleotide sequences of three previously undescribed Pseudomonas aeruginosa pilin structural genes are presented. Comparisons of deduced pilin primary structure and flanking DNA sequence allowed placement of these and six previously published sequences into one of two groups. Epitope mapping, using overlapping imm...

journal_title：Infection and immunity

authors： Castric PA,Deal CD

更新日期：1994-02-01 00:00:00

abstract：:The interactions between Klebsiella pneumoniae and the host environment at the site of infection are largely unknown. Pulmonary surfactant serves as an initial point of contact for inhaled bacteria entering the lung and is thought to contain molecular cues that aid colonization and pathogenesis. To gain insight into t...

journal_title：Infection and immunity

authors： Willsey GG,Ventrone S,Schutz KC,Wallace AM,Ribis JW,Suratt BT,Wargo MJ

更新日期：2018-06-21 00:00:00

abstract：:The objective of these studies was to determine the role of macrophage inflammatory protein 1alpha/CCL3 in pulmonary host defense during Klebsiella pneumoniae infection. Following intratracheal inoculation, 7-day survival of CCL3(-/-) mice was less than 10%, compared to 60% for CCL3(+/+) mice. Survival of CCR5(-/-) mi...

journal_title：Infection and immunity

authors： Lindell DM,Standiford TJ,Mancuso P,Leshen ZJ,Huffnagle GB

更新日期：2001-10-01 00:00:00

abstract：:Adherence to fibrinogen and fibronectin plays a crucial role in Staphylococcus aureus experimental endocarditis. Previous genetic studies have shown that infection and carriage isolates do not systematically differ in their virulence-related genes, including genes conferring adherence, such as clfA and fnbA. We set ou...

journal_title：Infection and immunity

authors： Ythier M,Entenza JM,Bille J,Vandenesch F,Bes M,Moreillon P,Sakwinska O

更新日期：2010-04-01 00:00:00

abstract：:The Plasmodium falciparum liver-stage antigen 3 (LSA3), a recently identified preerythrocytic antigen, induces protection against malaria in chimpanzees. Using antibodies from individuals with hyperimmunity to malaria affinity purified on recombinant or synthetic polypeptides of LSA3, we identified four non-cross-reac...

journal_title：Infection and immunity

authors： Brahimi K,Badell E,Sauzet JP,BenMohamed L,Daubersies P,Guérin-Marchand C,Snounou G,Druilhe P

更新日期：2001-06-01 00:00:00

abstract：:The enteric pathogens enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli employ a type 3 secretion system (T3SS) to manipulate the host inflammatory response during infection. Previously, it has been reported that EPEC, in a T3SS-dependent manner, induces an early proinflammatory response through a...

journal_title：Infection and immunity

authors： Pallett MA,Berger CN,Pearson JS,Hartland EL,Frankel G

更新日期：2014-11-01 00:00:00

abstract：:Growth in colonies with type 1 morphology and the presence of pili are characteristics that have been associated with virulence of gonococci for humans. To determine whether the presence of pili per se might be responsible for colony type 1 morphology, the relationship of pili to colony type was examined in various sp...

journal_title：Infection and immunity

authors： McGee ZA,Dourmashkin RR,Gross JG,Clark JB,Taylor-Robinson D

更新日期：1977-02-01 00:00:00

abstract：:The mannose-resistant, Proteus-like (MR/P) fimbria, responsible for mannose-resistant hemagglutination, is a virulence factor for uropathogenic Proteus mirabilis. Based on known fimbrial gene organization, we postulated that MrpG, a putative minor subunit of the MR/P fimbria, functions as an adhesin responsible for he...

journal_title：Infection and immunity

authors： Li X,Zhao H,Geymonat L,Bahrani F,Johnson DE,Mobley HL

更新日期：1997-04-01 00:00:00

abstract：:Capsular glucuronoxylomannans (GXM) of Cryptococcus neoformans var. neoformans isolates from patients with recurrent cryptococcal meningitis were analyzed by 1H nuclear magnetic resonance spectroscopy and for reactivity with factor sera (Iatron, Tokyo, Japan). For each patient the initial and relapse isolates had prev...

journal_title：Infection and immunity

authors： Cherniak R,Morris LC,Belay T,Spitzer ED,Casadevall A

更新日期：1995-05-01 00:00:00

abstract：:Clostridium botulinum serotype A produces a neurotoxin composed of a 100-kDa heavy chain and a 50-kDa light chain linked by a disulfide bond. This neurotoxin is part of a ca. 900-kDa complex, formed by noncovalent association with a single nontoxin, nonhemagglutinin subunit and a family of hemagglutinating proteins. P...

journal_title：Infection and immunity

authors： Maksymowych AB,Reinhard M,Malizio CJ,Goodnough MC,Johnson EA,Simpson LL

更新日期：1999-09-01 00:00:00

abstract：:Peritoneal exudate cells from chickens immunized with two species of coccidia, Eimeria tenella or Eimeria maxima, were examined for their capacity to phagocytose stages of the parasite in vitro. True phagocytosis of the sporozoite stage is difficult to estimate because of its ability to invade cells, but may be evalua...

journal_title：Infection and immunity

authors： Rose ME

更新日期：1974-10-01 00:00:00

abstract：:Several studies have demonstrated roles for eosinophils during innate and adaptive immune responses to helminth infections. However, evidence that eosinophils are capable of initiating an immune response to parasite antigens is lacking. The goal of the present in vitro study was to investigate the potential of eosinop...

journal_title：Infection and immunity

authors： Padigel UM,Lee JJ,Nolan TJ,Schad GA,Abraham D

更新日期：2006-06-01 00:00:00

abstract：:A cohort of 111 children from Bangui, Central African Republic, was surveyed for enteric Campylobacter infections from birth to the age of 2 years; stools were examined biweekly in these children until 6 months of age and at least four times per year thereafter until 2 years of age and after each diarrheal episode. Bl...

journal_title：Infection and immunity

authors： Martin PM,Mathiot J,Ipero J,Kirimat M,Georges AJ,Georges-Courbot MC

更新日期：1989-08-01 00:00:00

abstract：:Both idiopathic and infectious forms of colitis disrupt normal intestinal epithelial cell (IEC) proliferation and differentiation, although the mechanisms involved remain unclear. Recently, we demonstrated that infection by the attaching and effacing murine pathogen Citrobacter rodentium leads to a significant reducti...

journal_title：Infection and immunity

authors： Chan JM,Bhinder G,Sham HP,Ryz N,Huang T,Bergstrom KS,Vallance BA

更新日期：2013-12-01 00:00:00

abstract：:The role of the hypothalamus-pituitary-adrenal (HPA) axis in regulating the growth of Mycobacterium avium in Mycobacterium bovis BCG-resistant and -susceptible congenic mice was evaluated. Restraint was used to activate the HPA axis, which resulted in an increase in the level of corticosterone in the plasma. Activatio...

journal_title：Infection and immunity

authors： Brown DH,Sheridan J,Pearl D,Zwilling BS

更新日期：1993-11-01 00:00:00

abstract：:ExoU is a potent effector protein that causes rapid host cell death upon injection by the type III secretion system of Pseudomonas aeruginosa. The N-terminal half of ExoU contains a patatin-like phospholipase A(2) (PLA(2)) domain that requires the host cell cofactor superoxide dismutase 1 (SOD1) for activation, while ...

journal_title：Infection and immunity

authors： Veesenmeyer JL,Howell H,Halavaty AS,Ahrens S,Anderson WF,Hauser AR

更新日期：2010-08-01 00:00:00

abstract：:The adherence of Enterococcus faecalis strains to human T24 cells was examined by scanning electron microscopy. Five highly adhesive strains were identified from 30 strains isolated from the urine of patients with urinary tract infections. No efficiently adhesive strains were found among the 30 strains isolated from t...

journal_title：Infection and immunity

authors： Shiono A,Ike Y

更新日期：1999-04-01 00:00:00

abstract：:A monoclonal antibody (MAb) to Candida albicans (MAb B6.1) that protects against candidiasis and the nonprotective MAb B6 were compared for ability to support neutrophil (polymorphonuclear leukocyte [PMN]) candidacidal activity. Both MAbs are immunoglobulin M, and each recognizes distinct C. albicans mannan cell wall ...

journal_title：Infection and immunity

authors： Caesar-TonThat TC,Cutler JE

更新日期：1997-12-01 00:00:00

abstract：:Colonization of the mucosa of the stomach and the duodenum by Helicobacter pylori is the major cause of acute and chronic gastroduodenal pathologies in humans. Duodenal ulcer formation strongly correlates with the expression of an antigen (CagA) that is usually coeexpressed with the vacuolating cytotoxin (VacA), a pro...

journal_title：Infection and immunity

authors： Xiang Z,Censini S,Bayeli PF,Telford JL,Figura N,Rappuoli R,Covacci A

更新日期：1995-01-01 00:00:00

abstract：:Infectious pancreatic necrosis virus was stable for 10 days at 4 C in stream and well water, after which the virus had a half-life of 7.5 days. At 15 C, the virus was stable for 5 days, and then had a half-life between 5 and 6 days. Viral antigen in infected cells developed much more slowly at 4 C than at 20 C. Infect...

journal_title：Infection and immunity

authors： Tu KC,Spendlove RS,Goede RW

更新日期：1975-06-01 00:00:00

abstract：:Borrelia burgdorferi encodes a functional homolog of canonical Lon protease termed Lon-2. In addition, B. burgdorferi encodes a second Lon homolog called Lon-1. Recent studies suggest that Lon-1 may function differently from the prototypical Lon protease. However, the function of Lon-1 in B. burgdorferi biology remain...

journal_title：Infection and immunity

authors： Thompson C,Mason C,Parrilla S,Ouyang Z

更新日期：2020-05-20 00:00:00

abstract：:Urinary tract infections (UTIs) are among the most common infectious diseases of humans, with Escherichia coli responsible for >80% of all cases. One extreme of UTI is asymptomatic bacteriuria (ABU), which occurs as an asymptomatic carrier state that resembles commensalism. To understand the evolution and molecular me...

journal_title：Infection and immunity

authors： Beatson SA,Ben Zakour NL,Totsika M,Forde BM,Watts RE,Mabbett AN,Szubert JM,Sarkar S,Phan MD,Peters KM,Petty NK,Alikhan NF,Sullivan MJ,Gawthorne JA,Stanton-Cook M,Nhu NT,Chong TM,Yin WF,Chan KG,Hancock V,Ussery DW

更新日期：2015-05-01 00:00:00

abstract：:When immunocompetent mice are inoculated with Borrelia burgdorferi, they develop acute arthritis and carditis that undergo spontaneous regression despite the persistence of infection. Specific T- and/or B-cell immunity appears to be necessary for resolution of disease manifestations. Humoral immune responses to B. bur...

journal_title：Infection and immunity

authors： Bockenstedt LK,Barthold S,Deponte K,Marcantonio N,Kantor FS

更新日期：1993-05-01 00:00:00

abstract：:While several diseases associated with Chlamydia psittaci infection have been reported in Phascolarctos cinereus (koala), it is still unclear whether one or more chlamydial strains are responsible. In this study, we provide evidence, obtained by restriction enzyme and gene probe analysis, that two quite distinct strai...

journal_title：Infection and immunity

authors： Girjes AA,Hugall AF,Timms P,Lavin MF

更新日期：1988-08-01 00:00:00

abstract：:Tritrichomonas foetus is a serious veterinary pathogen, causing bovine trichomoniasis, a sexually transmitted disease leading to infertility and abortion. T. foetus infects the mucosal surfaces of the reproductive tract. Infection with T. foetus leads to apoptotic cell death of bovine vaginal epithelial cells (BVECs) ...

journal_title：Infection and immunity

authors： Singh BN,Lucas JJ,Hayes GR,Kumar I,Beach DH,Frajblat M,Gilbert RO,Sommer U,Costello CE

更新日期：2004-07-01 00:00:00

abstract：:Athymic BALB/c nude mice and euthymic BALB/c mice were infected with Rickettsia akari by the intraperitoneal route. The rickettsialpox infection was terminated in euthymic mice with only two intraperitoneal injections of the antibiotic oxytetracycline, whereas prolonged treatment was necessary to terminate the infecti...

journal_title：Infection and immunity

authors： Kenyon RH,Pedersen CE Jr

更新日期：1980-05-01 00:00:00

abstract：:Protection by surface antigen TF1.17 of Tritrichomonas foetus was investigated because it reacted with a monoclonal antibody which immobilized and mediated complement killing of the organism and prevented adherence to vaginal epithelial cells. This monoclonal antibody was used to demonstrate conservation of the antige...

journal_title：Infection and immunity

authors： BonDurant RH,Corbeil RR,Corbeil LB

更新日期：1993-04-01 00:00:00

abstract：:Porphyromonas gingivalis is a major etiologic agent of periodontitis, a chronic inflammatory disease that ultimately results in the loss of the supporting tissues of the teeth. Previous work has demonstrated the usefulness of avirulent Salmonella enterica serovar Typhimurium strains as antigen delivery systems for pro...

journal_title：Infection and immunity

authors： Kozarov E,Miyashita N,Burks J,Cerveny K,Brown TA,McArthur WP,Progulske-Fox A

更新日期：2000-02-01 00:00:00

abstract：:Passive protection, the administration of antibodies to prevent infection, has garnered significant interest in recent years as a potential prophylactic countermeasure to decrease the prevalence of hospital-acquired infections. Pili, polymerized protein structures covalently anchored to the peptidoglycan wall of many ...

journal_title：Infection and immunity

authors： Pinkston KL,Singh KV,Gao P,Wilganowski N,Robinson H,Ghosh S,Azhdarinia A,Sevick-Muraca EM,Murray BE,Harvey BR

更新日期：2014-04-01 00:00:00