Characterization of hemolysin of Moraxella bovis using a hemolysis-neutralizing monoclonal antibody.

abstract：:Bordetella bronchiseptica is a Gram-negative bacterium that infects and causes disease in a wide variety of animals. B. bronchiseptica also infects humans, thereby demonstrating zoonotic transmission. An extensive characterization of human B. bronchiseptica isolates is needed to better understand the distinct genetic ...

journal_title：Infection and immunity

authors： Sukumar N,Nicholson TL,Conover MS,Ganguly T,Deora R

更新日期：2014-04-01 00:00:00

abstract：:Rickettsia rickettsii infection of endothelial cells is manifested in very distinctive changes in cell morphology, consisting of extensive dilatation of the membranes of the endoplasmic reticulum and outer nuclear envelope and blebbing of the plasma membrane, as seen by transmission electron microscopy (D. J. Silverma...

journal_title：Infection and immunity

authors： Eremeeva ME,Silverman DJ

更新日期：1998-05-01 00:00:00

abstract：:Attachment of Fusobacterium nucleatum to various oral surfaces is mediated by several adhesins anchored on its outer surface. Monoclonal antibodies (MAbs) were prepared and used to identify the putative galactose-binding adhesin of F. nucleatum PK1594. Four unique MAbs, 8G7, 26B9, 28G11, and 29D4, were isolated on the...

journal_title：Infection and immunity

authors： Shaniztki B,Hurwitz D,Smorodinsky N,Ganeshkumar N,Weiss EI

更新日期：1997-12-01 00:00:00

abstract：:With large amounts of parasite gene sequence available, additional bioinformatic tools to screen these sequences for identifying genes encoding antigens are needed. Proteins containing tandem repeat (TR) domains are often B-cell antigens, and antibody responses toward TR domains of the proteins are dominant in human i...

journal_title：Infection and immunity

authors： Goto Y,Coler RN,Reed SG

更新日期：2007-02-01 00:00:00

abstract：:A family of high-molecular-weight (HMW) surface-exposed proteins important in the attachment of nontypeable Haemophilus influenzae (NTHi) to human epithelial cells was previously identified (J. W. St. Geme III, S. Falkow, and S. J. Barenkamp, Proc. Natl. Acad. Sci. USA 90:2875-2879, 1993). In the present investigation...

journal_title：Infection and immunity

authors： Bakaletz LO,Barenkamp SJ

更新日期：1994-10-01 00:00:00

abstract：:The ability of intracellular pathogens to sense and adapt to the hostile environment of the host is an important factor governing virulence. We have sequenced the operon encoding the major heat shock proteins GroES and GroEL in the gram-positive food-borne pathogen Listeria monocytogenes. The operon has a conserved or...

journal_title：Infection and immunity

authors： Gahan CG,O'Mahony J,Hill C

更新日期：2001-06-01 00:00:00

abstract：:Strains of Bacteroides fragilis associated with diarrhea in children (termed enterotoxigenic B. fragilis, or ETBF) produce a heat-labile ca. 20-kDa protein toxin (BFT). The purpose of this study was to examine the activity of BFT on polarized monolayers of human intestinal epithelial cells (T84 cells). In Ussing chamb...

journal_title：Infection and immunity

authors： Chambers FG,Koshy SS,Saidi RF,Clark DP,Moore RD,Sears CL

更新日期：1997-09-01 00:00:00

abstract：:Encapsulation of soluble protein antigens in liposomes was previously shown to result in processing of antigen via the major histocompatibility complex class I pathway, as evidenced by costaining of the trans-Golgi region of murine bone marrow-derived macrophages (BMs) by fluorophore-labeled liposomal antigen and by a...

journal_title：Infection and immunity

authors： Richards RL,Rao M,Wassef NM,Glenn GM,Rothwell SW,Alving CR

更新日期：1998-06-01 00:00:00

abstract：:Pathogen attachment to host cells is a key process during infection, and inhibition of pathogen adhesion is a promising approach to the prevention of infectious disease. We have previously shown that multivalent adhesion molecules (MAMs) are abundant in both pathogenic and commensal bacterial species, mediate early at...

journal_title：Infection and immunity

authors： Al-Saedi F,Stones DH,Vaz DP,Krachler AM

更新日期：2016-05-24 00:00:00

abstract：:Clostridium perfringens is an anaerobic, Gram-positive bacterium that causes a range of diseases in humans, including lethal gas gangrene. We have recently shown that strains of C. perfringens move across the surface of agar plates by a unique type IV pilus (TFP)-mediated social motility that had not been previously d...

journal_title：Infection and immunity

authors： Rodgers K,Arvidson CG,Melville S

更新日期：2011-08-01 00:00:00

abstract：:Immunoglobulin A (IgA) was prepared from samples of parotid saliva collected from two individuals over a 150-day period. Standardized solutions of the IgA were tested for agglutinating antibody activity against strains of streptococcus salivarius, S. sanguis, S. mitis, and S. mutans that had been isolated from a homol...

journal_title：Infection and immunity

authors： Bratthall D,Gibbons RJ

更新日期：1975-03-01 00:00:00

abstract：:Bacillus anthracis, the causative agent of anthrax, relies on multiple virulence factors to subvert the host immune defense. Using Caenorhabditis elegans as an infection model, we screened approximately 5,000 transposon mutants of B. anthracis Sterne for decreased virulence. One of the attenuated mutants resulted in l...

journal_title：Infection and immunity

authors： Franks SE,Ebrahimi C,Hollands A,Okumura CY,Aroian RV,Nizet V,McGillivray SM

更新日期：2014-03-01 00:00:00

abstract：:The intracellular protozoan Toxoplasma gondii is well known for its skill at invading and living within host cells. New discoveries are now also revealing the astounding ability of the parasite to inject effector proteins into the cytoplasm to seize control of the host cell. This review summarizes recent advances in o...

journal_title：Infection and immunity

authors： Denkers EY,Bzik DJ,Fox BA,Butcher BA

更新日期：2012-02-01 00:00:00

abstract：:ExoU is a potent effector protein that causes rapid host cell death upon injection by the type III secretion system of Pseudomonas aeruginosa. The N-terminal half of ExoU contains a patatin-like phospholipase A(2) (PLA(2)) domain that requires the host cell cofactor superoxide dismutase 1 (SOD1) for activation, while ...

journal_title：Infection and immunity

authors： Veesenmeyer JL,Howell H,Halavaty AS,Ahrens S,Anderson WF,Hauser AR

更新日期：2010-08-01 00:00:00

abstract：:Since 1984, it has been known that spotted fever group rickettsiosis exists in Japan. We isolated three strains of the causative rickettsiae, designated Katayama, Misaka, and Abe, from patients with the disease and studied the characteristics of the isolates. Nude mice and cyclophosphamide-treated mice died after infe...

journal_title：Infection and immunity

authors： Okada T,Tange Y,Kobayashi Y

更新日期：1990-04-01 00:00:00

abstract：:The recent finding that high numbers of strict anaerobes are present in the respiratory tract of cystic fibrosis (CF) patients has drawn attention to the pathogenic contribution of the CF microbiome to airway disease. In this study, we investigated the specific interactions of the most dominant bacterial CF pathogen, ...

journal_title：Infection and immunity

authors： Pustelny C,Komor U,Pawar V,Lorenz A,Bielecka A,Moter A,Gocht B,Eckweiler D,Müsken M,Grothe C,Lünsdorf H,Weiss S,Häussler S

更新日期：2015-01-01 00:00:00

abstract：:Legionella anisa and the amoeba Hartmannella vermiformis were isolated from an indoor fountain implicated as the infectious reservoir in an outbreak of Pontiac fever. We evaluated the ability of this strain of L. anisa to multiply in cultures of an amoeba (H. vermiformis), a ciliated protozoan (Tetrahymena pyriformis)...

journal_title：Infection and immunity

authors： Fields BS,Barbaree JM,Sanden GN,Morrill WE

更新日期：1990-09-01 00:00:00

abstract：:Vaccine antigen-specific antibody-secreting cell (ASC) responses in peripheral blood of healthy adult volunteers were studied after oral immunization with a prototype enterotoxigenic Escherichia coli (ETEC) vaccine by means of the enzyme-linked immunospot technique. Three doses of vaccine consisting of formalin-killed...

journal_title：Infection and immunity

authors： Wennerås C,Svennerholm AM,Ahrén C,Czerkinsky C

更新日期：1992-07-01 00:00:00

abstract：:Early-onset periodontitis (EOP) is characterized by rapidly progressive alveolar bone loss, chemotactic defects of neutrophils, and significant familial aggregation. We found immature myeloid lineage cells, defined as promyelocytes, in the peripheral blood in patients with EOP. A hematological examination of periphera...

journal_title：Infection and immunity

authors： Nemoto E,Nakamura M,Shoji S,Horiuchi H

更新日期：1997-09-01 00:00:00

abstract：:Previous studies have demonstrated that expression of virulence in Shigella spp. is controlled by growth temperature. To study the regulation of virulence (vir) genes, we set out to develop a rapid, easily-assayed phenotype with which to measure expression of virulence. This report described a procedure for isolating ...

journal_title：Infection and immunity

authors： Maurelli AT,Curtiss R 3rd

更新日期：1984-09-01 00:00:00

abstract：:A 10-amino-acid repeating sequence of the hemagglutinating portion of Clostridium difficile toxin A has been synthesized and used to produce antisera in rabbits. Antipeptide antibody inhibited toxin A-mediated hemagglutination and neutralized cytotoxic activity. Immunoblot analysis with the antipeptide antibody reveal...

journal_title：Infection and immunity

authors： Wren BW,Russell RR,Tabaqchali S

更新日期：1991-09-01 00:00:00

abstract：:Neospora caninum is a recently identified coccidian parasite which shares many features with, but is clearly distinct from, Toxoplasma gondii. N. caninum tachyzoites infect a wide range of mammalian cells both in vivo and in vitro. The mechanisms by which infection is achieved are largely unknown. Recent evidence has ...

journal_title：Infection and immunity

authors： Hemphill A

更新日期：1996-10-01 00:00:00

abstract：:Lipopolysaccharide (LPS) binding protein (LBP) is an acute-phase protein that enhances the responsiveness of immune cells to LPS by virtue of its capacity to transfer LPS to CD14. To determine the role of LBP in the innate immune response to peritonitis, LBP gene-deficient (LBP(-/-)) and normal wild-type mice were int...

journal_title：Infection and immunity

authors： Knapp S,de Vos AF,Florquin S,Golenbock DT,van der Poll T

更新日期：2003-12-01 00:00:00

abstract：:Streptococcus pneumoniae type 14 capsular polysaccharide-bovine serum albumin (S14PS-BSA) conjugates were prepared by water-soluble-carbodiimide-mediated condensation with or without the use of N-hydroxy-sulfosuccinimide. The immunogenicities of the capsular polysaccharide (S14PS) and of the conjugates were studied in...

journal_title：Infection and immunity

authors： Verheul AF,Versteeg AA,De Reuver MJ,Jansze M,Snippe H

更新日期：1989-04-01 00:00:00

abstract：:The fungus Cryptococcus neoformans has emerged as a major cause of meningoencephalitis worldwide. Host response to the fungus involves both innate and adaptive immunity, but fungal genes that modulate these processes are poorly understood. Previous studies demonstrated attenuated virulence of a mutant of a virulence-a...

journal_title：Infection and immunity

authors： Qiu J,Olszewski MA,Williamson PR

更新日期：2013-03-01 00:00:00

abstract：:In order to develop a new system for the analysis of capsular biosynthetic pathways we have explored the possibility of expressing type 3 capsular polysaccharide (CPS) from the pathogen Streptococcus pneumoniae in Lactococcus lactis, an unencapsulated lactic acid bacterium being developed as a vaccine delivery vehicle...

journal_title：Infection and immunity

authors： Gilbert C,Robinson K,Le Page RW,Wells JM

更新日期：2000-06-01 00:00:00

abstract：:Various pathogenic bacteria with the capacity to live within eukaryotic cells activate an apoptotic program in infected host cells. Induction of apoptosis by Listeria monocytogenes in murine dendritic cells and hepatocytes has been described. Here we address the questions of whether and how the pathogen kills macropha...

journal_title：Infection and immunity

authors： Barsig J,Kaufmann SH

更新日期：1997-10-01 00:00:00

abstract：:We demonstrate that transcription of the Staphylococcus aureus collagen adhesin gene (cna) is temporally regulated, with expression being highest in exponentially growing cultures and falling to almost undetectable levels as cultures enter the post-exponential-growth phase. The temporal regulation of cna transcription...

journal_title：Infection and immunity

authors： Gillaspy AF,Patti JM,Smeltzer MS

更新日期：1997-04-01 00:00:00

abstract：:Streptococcus equi is the causative agent of strangles, the most frequently diagnosed infectious disease of horses worldwide. The disease is characterized by abscessation and swelling of the lymph nodes of the head and neck, which can literally strangle the horse to death. S. equi produces four recently acquired phage...

journal_title：Infection and immunity

authors： Paillot R,Robinson C,Steward K,Wright N,Jourdan T,Butcher N,Heather Z,Waller AS

更新日期：2010-04-01 00:00:00

abstract：:Staphylococcus aureus is an important opportunistic pathogen and is the etiological agent of many hospital- and community-acquired infections. The golden pigment, staphyloxanthin, of S. aureus colonies distinguishes it from other staphylococci and related Gram-positive cocci. Staphyloxanthin is the product of a series...

journal_title：Infection and immunity

authors： Hall JW,Yang J,Guo H,Ji Y

更新日期：2017-01-26 00:00:00