Staphylococcus aureus superantigens elicit redundant and extensive human Vbeta patterns.

abstract：:Humoral immunity does not play a prominent role during experimental cryptococcosis. However, previous studies have shown that immunoglobulin G (IgG) anti-Cryptococcus neoformans antibodies can mediate cell-dependent yeast killing in vitro. Therefore, the protective effect of a previously described monoclonal IgG1 anti...

journal_title：Infection and immunity

authors： Dromer F,Charreire J,Contrepois A,Carbon C,Yeni P

更新日期：1987-03-01 00:00:00

abstract：:Vaccination has been proposed for the prevention of disease due to enterohemorrhagic Escherichia coli (EHEC), but the immune response following human infection, including the choice of potential antigens, has not been well characterized. To study this, sera were obtained from five pediatric patients with acute diarrhe...

journal_title：Infection and immunity

authors： Li Y,Frey E,Mackenzie AM,Finlay BB

更新日期：2000-09-01 00:00:00

abstract：:After intranasal inoculation, Brucella melitensis chronically infects the mononuclear phagocyte system in BALB/c mice, but it causes no apparent illness. Adaptive immunity, which can be transferred by either T cells or antibody from immune to naive animals, confers resistance to challenge infection. The role of innate...

journal_title：Infection and immunity

authors： Izadjoo MJ,Polotsky Y,Mense MG,Bhattacharjee AK,Paranavitana CM,Hadfield TL,Hoover DL

更新日期：2000-09-01 00:00:00

abstract：:In this study, we examined the binding of Candida albicans synchronized yeast-phase cells to plastic, immobilized amino acids and bovine serum albumin (BSA) and quantified the binding by using an XTT tetrazolium salt assay and absorbance determination. Our results show that C. albicans binds efficiently and specifical...

journal_title：Infection and immunity

authors： Hawser SP,Islam K

更新日期：1998-01-01 00:00:00

abstract：:Preliminary studies established methods for obtaining maximum yields of viable cells. Liquid shaken cultures of Histoplasma capsulatum provided a maximum of 4 x 10(8) to 5 x 10(8) cells/ml regardless of the inoculum size. Under optimum conditions, cells were viable (90 to 95%) for 168 to 240 hr. Generation times range...

journal_title：Infection and immunity

authors： Garcia JP,Howard DH

更新日期：1971-08-01 00:00:00

abstract：:Lipopolysaccharide (LPS) binding protein (LBP) is an acute-phase protein that enhances the responsiveness of immune cells to LPS by virtue of its capacity to transfer LPS to CD14. To determine the role of LBP in the innate immune response to peritonitis, LBP gene-deficient (LBP(-/-)) and normal wild-type mice were int...

journal_title：Infection and immunity

authors： Knapp S,de Vos AF,Florquin S,Golenbock DT,van der Poll T

更新日期：2003-12-01 00:00:00

abstract：:The application of dissociation techniques, involving gel filtration in the presence of guanidine, to a semipurified preparation of Campylobacter jejuni heat-labile enterotoxin yielded a material whose functional and immunological properties resemble those of the B subunits of cholera toxin and Escherichia coli heat-l...

journal_title：Infection and immunity

authors： Klipstein FA,Engert RF

更新日期：1985-06-01 00:00:00

abstract：:Migration of the fungal pathogen Candida albicans across the endothelial cell layer is considered a prerequisite for the invasion of multiple organs occurring in systemic candidiasis. We developed an experimental system in which C. albicans migrates from a luminal compartment across a monolayer of bovine aortic endoth...

journal_title：Infection and immunity

authors： Zink S,Nass T,Rösen P,Ernst JF

更新日期：1996-12-01 00:00:00

abstract：:Hot phenol-water extraction of smooth Brucella abortus and B. melitensis cells yielded a toxic fraction which was recovered from the phenol phase (fraction 5). Chemically, fractions 5 from both Brucella species were lipid-carbohydrate-protein-2 keto-3-deoxyoctulosonic acid complexes which were stable to heat and resis...

journal_title：Infection and immunity

authors： Leong D,Diaz R,Milner K,Rudbach J,Wilson JB

更新日期：1970-02-01 00:00:00

abstract：:We have investigated the ability of two species of streptococci isolated from the human oral cavity (Streptococcus mutans NCTC 10449 and Streptococcus sobrinus SL-1) to metabolize N-acetylglucosamine (GlcNAc), a naturally occurring amino sugar present in saliva and human glycoproteins, when provided as the sole fermen...

journal_title：Infection and immunity

authors： Homer KA,Patel R,Beighton D

更新日期：1993-01-01 00:00:00

abstract：:An enzyme from Treponema denticola that hydrolyzes a synthetic trypsin substrate, N-alpha-benzoyl-L-arginine-p-nitroanilide (BAPNA), was purified to near homogeneity, as judged by gel electrophoresis. The molecular weight of the enzyme was estimated to be ca. 69,000 by sodium dodecyl sulfate-polyacrylamide gel electro...

journal_title：Infection and immunity

authors： Ohta K,Makinen KK,Loesche WJ

更新日期：1986-07-01 00:00:00

abstract：:Evidence obtained from gene knockout studies supports the role of Toll-like receptor 4 (TLR4) in intestinal inflammation and microbiota recognition. Increased epithelial TLR4 expression is observed in patients with inflammatory bowel disease. However, little is known of the effect of increased TLR4 signaling on intest...

journal_title：Infection and immunity

authors： Dheer R,Santaolalla R,Davies JM,Lang JK,Phillips MC,Pastorini C,Vazquez-Pertejo MT,Abreu MT

更新日期：2016-01-11 00:00:00

abstract：:Culture filtrate from Mycobacterium tuberculosis contains protective antigens of relevance for the generation of a new antituberculosis vaccine. We have identified two previously uncharacterized M. tuberculosis proteins (TB7.3 and TB10.4) from the highly active low-mass fraction of culture filtrate. The molecules were...

journal_title：Infection and immunity

authors： Skjøt RL,Oettinger T,Rosenkrands I,Ravn P,Brock I,Jacobsen S,Andersen P

更新日期：2000-01-01 00:00:00

abstract：:In experiments described herein, it was observed that guinea pigs with delayed-type hypersensitivity to tuberculoproteins under various experimental conditions, with or without passive transfer of serum from immune donors, manifested no acquired immunity against aerogenically induced tuberculosis. These results are di...

journal_title：Infection and immunity

authors： Reggiardo Z,Middlebrook G

更新日期：1974-05-01 00:00:00

abstract：:Antiserum and purified immunoglobulin directed against Mycoplasma pneumoniae membrane protein P1 were examined for their influence on mycoplasma viability, metabolism, and cytadsorption. Anti-P1 immunoglobulin inhibited adherence of M. pneumoniae to hamster tracheal rings in vitro by up to 80% and inhibited hemadsorpt...

journal_title：Infection and immunity

authors： Krause DC,Baseman JB

更新日期：1983-03-01 00:00:00

abstract：:To analyze the role of interleukin-10 (IL-10) in bacterial cerebral infections, we studied cerebral listeriosis in IL-10-deficient (IL-10(-/-)) and wild-type (WT) mice, the latter of which express high levels of IL-10 in both primary and secondary cerebral listeriosis. IL-10(-/-) mice succumbed to primary as well as s...

journal_title：Infection and immunity

authors： Deckert M,Soltek S,Geginat G,Lütjen S,Montesinos-Rongen M,Hof H,Schlüter D

更新日期：2001-07-01 00:00:00

abstract：:Immune cytolysis was measured by release of absorbed radioactive chromium from infected cells that were incubated with antiviral antibody and complement. The presence of virus-specific antigens detected in this manner on the surface of several types of cells infected with Japanese encephalitis (JE) virus did not corre...

journal_title：Infection and immunity

authors： Brandt WE,Russell PK

更新日期：1975-02-01 00:00:00

abstract：:Oligopeptides play important roles in bacterial nutrition and signaling. Using sequences from the available genome database for Mycobacterium tuberculosis H37Rv, the oligopeptide permease operon (oppBCDA) of Mycobacterium bovis BCG was cloned from a cosmid library. An opp mutant strain was constructed by homologous re...

journal_title：Infection and immunity

authors： Green RM,Seth A,Connell ND

更新日期：2000-02-01 00:00:00

abstract：:In order to determine the carrier nature of lipopolysaccharide from Brucella abortus (LPS-BA) in evoking humoral responses, normal and immunodeficient mice were immunized with trinitrophenyl (TNP)-conjugated LPS-BA (TNP-LPS-BA) and the responses were compared with those to known T-dependent and T-independent antigens....

journal_title：Infection and immunity

authors： Betts M,Beining P,Brunswick M,Inman J,Angus RD,Hoffman T,Golding B

更新日期：1993-05-01 00:00:00

abstract：:We determined the diphtheria toxin phenotype of specially selected isolates of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis (C. ovis). All produced proteins similar in size and immunological structure to diphtheria toxin. As with diphtheria toxin, they exhibited ADP-ribosylating activity, and their ...

journal_title：Infection and immunity

authors： Wong TP,Groman N

更新日期：1984-03-01 00:00:00

abstract：:Intracellular multiplication of virulent Legionella pneumophila serogroup 1 was inhibited by human monocyte-derived macrophages activated by a glycoprotein extract of Klebsiella pneumoniae, RU 41.740. Macrophage cultures were infected with L. pneumophila in the presence of immune antibodies on day 7 of culture. Extrac...

journal_title：Infection and immunity

authors： Rajagopalan P,Dournon E,Vildé JL,Pocidalo JJ

更新日期：1987-09-01 00:00:00

abstract：:The bactericidal activity of guinea pig and human polymorphonuclear leukocytes (PMNs) against a smooth-intermediate strain (45/0) and a rough strain (45/20) of Brucella abortus has been examined. After incubation for 120 min, guinea pig PMNs incubated with either the smooth strain 45/0 or the rough strain 45/20 exhibi...

journal_title：Infection and immunity

authors： Kreutzer DL,Dreyfus LA,Robertson DC

更新日期：1979-03-01 00:00:00

abstract：:Phagocytosis of unopsonized Salmonella typhimurium 395, MR-10, opsonized Salmonella typhimurium 395 MS, and Staphylococcus epidermidis by rabbit polymorphonuclear leukocytes was inhibited by heparin at concentrations as low as 0.5 U/ml. Inhibition was dose dependent and nearly complete at 20 U/ml. Provided that hepari...

journal_title：Infection and immunity

authors： Victor M,Weiss J,Elsbach P

更新日期：1981-04-01 00:00:00

abstract：:TB10.4 is a newly identified antigen of Mycobacterium tuberculosis recognized by human and murine T cells upon mycobacterial infection. Here, we show that immunization with Mycobacterium bovis BCG induces a strong, genetically controlled, Th1 immune response against TB10.4 in mice. BALB/c and C57BL/6 strains behave as...

journal_title：Infection and immunity

authors： Hervas-Stubbs S,Majlessi L,Simsova M,Morova J,Rojas MJ,Nouzé C,Brodin P,Sebo P,Leclerc C

更新日期：2006-06-01 00:00:00

abstract：:Yersinia pestis evolved from Y. pseudotuberculosis to become the causative agent of bubonic and pneumonic plague. We identified a homolog of the Salmonella enterica serovar Typhimurium lipoprotein (lpp) gene in Yersinia species and prepared lpp gene deletion mutants of Y. pseudotuberculosis YPIII, Y. pestis KIM/D27 (p...

journal_title：Infection and immunity

authors： Sha J,Agar SL,Baze WB,Olano JP,Fadl AA,Erova TE,Wang S,Foltz SM,Suarez G,Motin VL,Chauhan S,Klimpel GR,Peterson JW,Chopra AK

更新日期：2008-04-01 00:00:00

abstract：:Free lipid A of Bordetella pertussis, Neisseria meningitidis, and Escherichia coli lipopolysaccharide (LPS) was prepared by hydrolysis in acetate buffer (pH 4.5); in addition, lipid A from B. pertussis and E. coli was prepared by hydrolysis in mineral acid (HCl). The precipitates obtained were purified by extraction m...

journal_title：Infection and immunity

authors： Caroff M,Cavaillon JM,Fitting C,Haeffner-Cavaillon N

更新日期：1986-11-01 00:00:00

abstract：:Harvard caries-resistant rats (CR) monoassociated with cariogenic Streptococcus faecalis (SF) for 150 days developed early high levels of specific SF serum agglutinins, moderate levels of salivary antibody, and little or no caries activity. Harvard caries-susceptible (CS) SF-monoassociated rats developed serum antibod...

journal_title：Infection and immunity

authors： Peri BA,Wagner M

更新日期：1977-06-01 00:00:00

abstract：:Bacterial recognition of host sialic acid-containing receptors plays an important role in microbial colonization of the human oral cavity. The sialic acid-binding adhesin of Streptococcus gordonii DL1 was previously associated with the hsa gene encoding a 203-kDa protein. The predicted protein sequence consists of an ...

journal_title：Infection and immunity

authors： Takahashi Y,Yajima A,Cisar JO,Konishi K

更新日期：2004-07-01 00:00:00

abstract：:The suspected correlation between cessation of type C virus production and halt in immunoglobulin secretion by murine myeloma cells was studied. Employing two variants of the murine myeloma MOPC-315, immunoglobulin A-producing and nonproducing cells, we demonstrated that the two myelomas release similar levels of type...

journal_title：Infection and immunity

authors： Gazit A,Yaniv A,Halperin D,Ben-Efraim S

更新日期：1979-08-01 00:00:00

abstract：:A murine model system was established to study immune responses to the Pnu-Imune vaccine, which is made up of 23 different pneumococcal capsular polysaccharides. In this animal model, antibody-forming cell responses to 21 of 23 individual polysaccharides in the vaccine were detected. The Pnu-Imune vaccine elicited goo...

journal_title：Infection and immunity

authors： Garg M,Subbarao B

更新日期：1992-06-01 00:00:00