Experimental infection of newly weaned pigs with human and porcine strains of Serpulina pilosicoli.

abstract：:Oral administration of polymyxin to specific-pathogen-free C3H/Law mice which with previously contaminated with gram-negative bacteria resulted in complete suppression of cecal gram-negative bacteria. Suppression of cecal gram-negative bacteria was accompanied by reduction of the cecal endotoxin concentration from 10 ...

journal_title：Infection and immunity

authors： Goris H,de Boer F,van der Waaij D

更新日期：1985-11-01 00:00:00

abstract：:Aspergillus fumigatus produces conidia that are highly dispersable and resistant to degradation. We have sought to analyze these properties by studying the rodlets which form the outer spore coat protein. Degenerate primers based on hydrophobins in other fungi were applied to genomic DNA from A. fumigatus in PCR. A pr...

journal_title：Infection and immunity

authors： Parta M,Chang Y,Rulong S,Pinto-DaSilva P,Kwon-Chung KJ

更新日期：1994-10-01 00:00:00

abstract：:The expression of T cell differentiation markers is known to increase during Mycobacterium tuberculosis infection, and yet the biological role of such markers remains unclear. We examined the requirement of the T cell differentiation marker killer cell lectin-like receptor G1 (KLRG1) during M. tuberculosis infection u...

journal_title：Infection and immunity

authors： Cyktor JC,Carruthers B,Stromberg P,Flaño E,Pircher H,Turner J

更新日期：2013-04-01 00:00:00

abstract：:Chlamydia trachomatis L2 is an obligate intracellular microorganism with a unique biphasic life cycle. The extracellular form, the elementary body (EB), is infectious but metabolically inactive. Attachment of EBs to host cells is medicated by a heparan sulfate-like glycosaminoglycan. Following attachment, the EB is in...

journal_title：Infection and immunity

authors： Birkelund S,Johnsen H,Christiansen G

更新日期：1994-11-01 00:00:00

abstract：:A hemolysin that appears to be responsible for the zones of beta-hemolysis surrounding colonies of group B streptococci (Streptococcus agalactiae) on blood agar plates has been isolated and partially purified. No soluble hemolysin was detectable in the supernatants of streptococcal cultures grown in several types of m...

journal_title：Infection and immunity

authors： Marchlewicz BA,Duncan JL

更新日期：1980-12-01 00:00:00

abstract：:The search to identify Mycobacterium tuberculosis antigens capable of conferring protective immunity against tuberculosis has received a boost owing to the resurgence of tuberculosis over the past two decades. It has long been recognized that lymphoid cells are required for protection against M. tuberculosis. While tr...

journal_title：Infection and immunity

authors： Kumar P,Amara RR,Challu VK,Chadda VK,Satchidanandam V

更新日期：2003-04-01 00:00:00

abstract：:The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The asymmetric character and unique biochemistry of LPS molecules contribute to the OM's ability to function as a molecular permeability barrier tha...

journal_title：Infection and immunity

authors： Giordano NP,Cian MB,Dalebroux ZD

更新日期：2020-06-22 00:00:00

abstract：:Cell surface protein SSP-5 in the oral bacterium Streptococcus gordonii M5 binds human salivary agglutinin in a Ca(2+)-dependent reaction (D.R. Demuth, E.E. Golub, and D. Malamud, J. Biol. Chem. 265:7120-7126, 1990). The region of the gene encoding an N-terminal segment of a related polypeptide (SspA) in S. gordonii D...

journal_title：Infection and immunity

authors： Jenkinson HF,Terry SD,McNab R,Tannock GW

更新日期：1993-08-01 00:00:00

abstract：:We have previously shown that splenocytes from mice acutely infected with Trypanosoma cruzi exhibit high levels of nitric oxide (NO)-mediated apoptosis. In the present study, we used the gamma interferon (IFN-gamma)-knockout (IFN-gamma(-/-)) mice to investigate the role of IFN-gamma in modulating apoptosis induction a...

journal_title：Infection and immunity

authors： Martins GA,Vieira LQ,Cunha FQ,Silva JS

更新日期：1999-08-01 00:00:00

abstract：:Immunization with avirulent Salmonella typhimurium strain SL3235, a smooth, aroA- derivative, was shown to induce high levels of resistance to challenge with virulent S. typhimurium in innately hypersusceptible C3H/HeJ mice and inherently resistant C3H/HeNCrlBR mice. Strain SL3235 is one of a class of avirulent aroA- ...

journal_title：Infection and immunity

authors： Killar LM,Eisenstein TK

更新日期：1985-03-01 00:00:00

abstract：:The antigenically conserved proteins of Treponema pallidum subsp. pallidum and four nonpathogenic cultivatable treponemes were investigated by phase partitioning with the nonionic detergent Triton X-114 and immunoblot analysis. None of the T. pallidum integral membrane proteins identified by phase partitioning (deterg...

journal_title：Infection and immunity

authors： Radolf JD,Norgard MV

更新日期：1988-07-01 00:00:00

abstract：:Patients with chronic bronchitis are colonized by and may develop acute bronchopulmonary infection due to nontypable Haemophilus influenzae (NTHI) despite the presence of bactericidal and opsonizing antibody to the infecting organism. To test the hypothesis that secretory immunoglobulin A (IgA) interferes with host de...

journal_title：Infection and immunity

authors： Musher DM,Goree A,Baughn RE,Birdsall HH

更新日期：1984-07-01 00:00:00

abstract：:Trichinella spiralis creates a unique intracellular habitat in striated muscle. We report that a proteoglycan, syndecan-1, is induced early in infection yet is not essential for habitat development and exerts a modest influence on the immune response. This report is the first to address the requirement for a specific ...

journal_title：Infection and immunity

authors： Beiting DP,Park PW,Appleton JA

更新日期：2006-03-01 00:00:00

abstract：:Cell-mediated immune (CMI) responses and tumor necrosis factor alpha (TNF-alpha) have been shown to be essential in acquired protection against Cryptococcus neoformans. Induction of a protective anticryptococcal CMI response includes increases in dendritic cells (DC) and activated CD4(+) T cells in draining lymph node...

journal_title：Infection and immunity

authors： Bauman SK,Huffnagle GB,Murphy JW

更新日期：2003-01-01 00:00:00

abstract：:Galactomannan (GM) extracted from mycelia of Aspergillus fumigatus with cold dilute alkali reacted with antiserum specific for an antigen that circulated in invasive aspergillosis in rabbits and humans. The GM was purified by its affinity for concanavalin A and was separated from a nonantigenic glucan by gel permeatio...

journal_title：Infection and immunity

authors： Reiss E,Lehmann PF

更新日期：1979-07-01 00:00:00

abstract：:The influence of the growth medium on the ability of strains of Streptococcus mutans, Actinomyces viscosus and A. naeslundii to attach to saliva-treated hydroxyapatite (S-HA) surfaces was studied. Preliminary experiments indicated that cells of each species harvested in lag, log, and early stationary phases of growth ...

journal_title：Infection and immunity

authors： Peros WJ,Gibbons RJ

更新日期：1981-04-01 00:00:00

abstract：:A Pasteurella haemolytica mutant incapable of producing leukotoxin was created by allelic replacement. Concentrated culture supernatants from wild-type P. haemolytica, but not from the mutant, contained the 102-kDa leukotoxin protein and lysed bovine lymphoma cells and sheep erythrocytes. Wild-type P. haemolytica demo...

journal_title：Infection and immunity

authors： Murphy GL,Whitworth LC,Clinkenbeard KD,Clinkenbeard PA

更新日期：1995-08-01 00:00:00

abstract：:In this analysis we have examined in detail the effects of low concentrations of zinc on the growth and dimorphism of Candida albicans. Evidence is presented that micromolar concentrations of zinc added to growth cultures grown at 25 degrees C (i) cause a twofold increase in the final concentration of spheres at satio...

journal_title：Infection and immunity

authors： Bedell GW,Soll DR

更新日期：1979-10-01 00:00:00

abstract：:Assembly of adherent biofilms is the key mechanism involved in Staphylococcus epidermidis virulence during device-associated infections. Aside from polysaccharide intercellular adhesin (PIA), the accumulation-associated protein Aap and the extracellular matrix binding protein Embp act as intercellular adhesins, mediat...

journal_title：Infection and immunity

authors： Schommer NN,Christner M,Hentschke M,Ruckdeschel K,Aepfelbacher M,Rohde H

更新日期：2011-06-01 00:00:00

abstract：:Oligosaccharides (OSs) related to the pneumococcal type 14 capsular polysaccharide (Pn14PS) were studied for their ability to inhibit the binding between anti-PS14 antisera and native PS14. A synthetic tetrasaccharide corresponding to the repeating unit of the Pn14PS, a hexasaccharide mimic, and an octasaccharide frag...

journal_title：Infection and immunity

authors： Mawas F,Niggemann J,Jones C,Corbel MJ,Kamerling JP,Vliegenthart JF

更新日期：2002-09-01 00:00:00

abstract：:Chronic lung infection by Pseudomonas aeruginosa causes significant morbidity in cystic fibrosis patients initiated by the failure of innate immune responses. We used microarray analysis and real-time PCR to detect transcriptional changes associated with cytokine production in isogenic bronchial epithelial cell lines ...

journal_title：Infection and immunity

authors： Reiniger N,Ichikawa JK,Pier GB

更新日期：2005-10-01 00:00:00

abstract：:Conventionally raised suckling mice were injected intragastrically with 10(5) spores of a Clostridium botulinum type A culture. Botulism was not observed, but 80% or more of mice challenged when 8 to 11 days old had botulinum toxin in the large intestine 3 days later. Mice younger than 7 days or older than 15 days wer...

journal_title：Infection and immunity

authors： Sugiyama H,Mills DC

更新日期：1978-07-01 00:00:00

abstract：:Seven antigens of Borrelia hermsii, B. parkeri, and B. turicatae with isoelectric points in the range of 4.4 to 5.0 and molecular masses of 40 to 43 kilodaltons played a role in the relapse phenomenon of relapsing fever. Based upon location of the antigens in the outer envelope, the molecular weight, and Western blot ...

journal_title：Infection and immunity

authors： Kehl KS,Farmer SG,Komorowski RA,Knox KK

更新日期：1986-12-01 00:00:00

abstract：:Cells of Candida albicans strain WO-1 and related strains switch frequently and reversibly between a white-colony-forming unit (white phase) and a gray-colony-forming unit (opaque phase). Cells in the budding white phase exhibit the usual smooth round phenotype observed in other C. albicans strains, but cells in the b...

journal_title：Infection and immunity

authors： Anderson J,Cundiff L,Schnars B,Gao MX,Mackenzie I,Soll DR

更新日期：1989-02-01 00:00:00

abstract：:Tuberculosis is one of the most important infectious diseases worldwide. The susceptibility to this disease depends to a great extent on the innate immune response against mycobacteria. Host defense peptides (HDP) are one of the first barriers to counteract infection. Cathelicidin (LL-37) is an HDP that has many immun...

journal_title：Infection and immunity

authors： Torres-Juarez F,Cardenas-Vargas A,Montoya-Rosales A,González-Curiel I,Garcia-Hernandez MH,Enciso-Moreno JA,Hancock RE,Rivas-Santiago B

更新日期：2015-12-01 00:00:00

abstract：:Lesions caused by Leishmania amazonensis normally heal, but relapses occur due to parasite persistence in host tissues. It has been proposed that infection of fibroblasts plays an important role in this process by providing the parasites with a safe haven in which to replicate. However, most previous studies have focu...

journal_title：Infection and immunity

authors： Morehead J,Coppens I,Andrews NW

更新日期：2002-08-01 00:00:00

abstract：:The mechanism by which Helicobacter pylori, which has little or no invasive activity, induces gastric-tissue inflammation and injury has not been well characterized. We have previously demonstrated that water-extracted proteins of H. pylori are capable of activating human monocytes by a lipopolysaccharide (LPS)-indepe...

journal_title：Infection and immunity

authors： Pérez-Pérez GI,Shepherd VL,Morrow JD,Blaser MJ

更新日期：1995-04-01 00:00:00

abstract：:In mammals, the natural resistance-associated macrophage protein 1 gene, Nramp1, plays a major role in resistance to mycobacterial infections. Chesapeake Bay striped bass (Morone saxatilis) is currently experiencing an epizootic of mycobacteriosis that threatens the health of this ecologically and economically importa...

journal_title：Infection and immunity

authors： Burge EJ,Gauthier DT,Ottinger CA,Van Veld PA

更新日期：2004-03-01 00:00:00

abstract：:A gene, dmcA, expressing a methyl-accepting chemotaxis protein (MCP) from the oral spirochete Treponema denticola has been characterized. The gene was initially identified as an open reading frame immediately upstream from the previously characterized prtB protease gene of strain ATCC 35405. Nucleotide sequencing of t...

journal_title：Infection and immunity

authors： Kataoka M,Li H,Arakawa S,Kuramitsu H

更新日期：1997-10-01 00:00:00

abstract：:Intracellular survival of Chlamydia psittaci is in part dependent on the ability of the organism to thwart phagolysosome formation. Circumvention of phagolysosome fusion could be either localized to chlamydia-laden vacuoles or generalized to all phagosomes in the host cell. To determine which of these modes is in oper...

journal_title：Infection and immunity

authors： Eissenberg LG,Wyrick PB

更新日期：1981-05-01 00:00:00