Endogenous gamma interferon is essential in granuloma formation induced by glycolipid-containing mycolic acid in mice.

abstract：:Yersinia enterocolitica serotype 9 contained an antigenic component giving a reaction of total identity with Brucella native hapten and polysaccharide B. This component was present in a phenol-water extract (fraction 5; M. Redfearn, Ph.D. Thesis, University of Wisconsin, Madison, 1960) along with the smooth lipopolysa...

journal_title：Infection and immunity

authors： Fernandez-Lago L,Moriyon I,Toyos J,Diaz R

更新日期：1982-11-01 00:00:00

abstract：:We have determined the amounts of specific anti-class 1 outer membrane protein antibodies in sera from 25 patients during the course of systemic meningococcal disease, using purified class 1 protein as the sensitizing antigen in an enzyme-linked immunosorbent assay. The class 1 protein was obtained from a variant of s...

journal_title：Infection and immunity

authors： Guttormsen HK,Wetzler LM,Solberg CO

更新日期：1994-04-01 00:00:00

abstract：:Mice were inoculated with Legionella pneumophila via an intratracheal route to establish an experimental model of infection. Lung lavage fluid obtained from infected mice contained a cytolytic factor identified as tumor necrosis factor (TNF). Peak levels of TNF were produced at about 24 h postinfection and rapidly dec...

journal_title：Infection and immunity

authors： Blanchard DK,Djeu JY,Klein TW,Friedman H,Stewart WE 2nd

更新日期：1987-02-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for large numbers of postsurgical nosocomial infections across the United States and worldwide. Propofol anesthesia is widely used in surgery and in intensive care units, and recent evidence indicates that even brief exposure to propofol can substantial...

journal_title：Infection and immunity

authors： Visvabharathy L,Freitag NE

更新日期：2017-06-20 00:00:00

abstract：:Hamster trachea organ cultres were shown to consume measurable amounts of oxygen when incubated in a closed micro-chamber. Several simple and complex media were evaluated, and the optimal system involved incubating 2 to 4 mg of tracheal tissue in Tyrodes balanced salt solution at 37 C for 60 min, with oxygen activity ...

journal_title：Infection and immunity

authors： Gabridge MG

更新日期：1975-09-01 00:00:00

abstract：:Persistent infection with Borrelia burgdorferi in the presence of a vigorous host immune response has been demonstrated in humans and in animal models of Lyme disease. Long-term persistence of B. burgdorferi was documented recently in our studies of BALB/c and C3H mice infected with cloned and uncloned strains of B. b...

journal_title：Infection and immunity

authors： Persing DH,Mathiesen D,Podzorski D,Barthold SW

更新日期：1994-08-01 00:00:00

abstract：:A clone bank of Pasteurella haemolytica A1 was constructed by partial digestion of the genomic DNA with Sau3A and ligation of 5- to 10-kilobase-pair fragments into the BamHI site of the plasmid vector pBR322. After transformation into Escherichia coli K-12, a total of 4 X 10(3) recombinant clones was obtained. These w...

journal_title：Infection and immunity

authors： Lo RY,Shewen PE,Strathdee CA,Greer CN

更新日期：1985-12-01 00:00:00

abstract：:Virulent Streptococcus suis serotype 2 strains are invasive extracellular bacteria causing septicemia and meningitis in piglets and humans. One objective of this study was to elucidate the function of complement in innate immune defense against S. suis. Experimental infection of wild-type (WT) and C3(-/-) mice demonst...

journal_title：Infection and immunity

authors： Seitz M,Beineke A,Singpiel A,Willenborg J,Dutow P,Goethe R,Valentin-Weigand P,Klos A,Baums CG

更新日期：2014-06-01 00:00:00

abstract：:Once Candida albicans comes in contact with endothelial cells, it induces cellular injury. This endothelial cell injury may be a mechanism by which blood-borne organisms escape from the intravascular compartment and invade the tissue parenchyma during hematogenous infection. We have been investigating the ability of c...

journal_title：Infection and immunity

authors： Fratti RA,Ghannoum MA,Edwards JE Jr,Filler SG

更新日期：1996-11-01 00:00:00

abstract：:Previously we demonstrated that recombinant murine interleukin-12 (rmIL-12) administration can promote a primary Th1 response while suppressing the Th2 response in mice primed with 2,4, 6-trinitrophenyl-keyhole limpet hemocyanin (TNP-KLH). The present studies examined the capacity of rmIL-12 to drive a Th1 response to...

journal_title：Infection and immunity

authors： Schopf LR,Bliss JL,Lavigne LM,Chung CL,Wolf SF,Sypek JP

更新日期：1999-05-01 00:00:00

abstract：:Mesophilic Aeromonas hydrophila strains of serotype O34 typically express smooth lipopolysaccharide (LPS) on their surface. A single mutation in the gene that codes for UDP N-acetylgalactosamine 4-epimerase (gne) confers the O(-) phenotype (LPS without O-antigen molecules) on a strain in serotypes O18 and O34, but not...

journal_title：Infection and immunity

authors： Canals R,Jiménez N,Vilches S,Regué M,Merino S,Tomás JM

更新日期：2006-01-01 00:00:00

abstract：:We have previously demonstrated the existence of Klebsiella pneumoniae clinical isolates deficient in the lipopolysaccharide O side chain, the major factor for resistance to complement-mediated killing in this bacterial species. These isolates are complement resistant, and their mechanisms to resist complement were in...

journal_title：Infection and immunity

authors： Alvarez D,Merino S,Tomás JM,Benedí VJ,Albertí S

更新日期：2000-02-01 00:00:00

abstract：:Chronic actinomycetoma associated with grain production was induced in BALB/c mice by subcutaneous inoculation of live Nocardia brasiliensis in Freund incomplete adjuvant into the hind footpads. Similar inoculation of N. asteroides and N. caviae resulted in local tumor formation which healed spontaneously after 5 mont...

journal_title：Infection and immunity

authors： Zlotnik H,Buckley HR

更新日期：1980-09-01 00:00:00

abstract：:The influence of the growth medium on the ability of strains of Streptococcus mutans, Actinomyces viscosus and A. naeslundii to attach to saliva-treated hydroxyapatite (S-HA) surfaces was studied. Preliminary experiments indicated that cells of each species harvested in lag, log, and early stationary phases of growth ...

journal_title：Infection and immunity

authors： Peros WJ,Gibbons RJ

更新日期：1981-04-01 00:00:00

abstract：:Evidence obtained from gene knockout studies supports the role of Toll-like receptor 4 (TLR4) in intestinal inflammation and microbiota recognition. Increased epithelial TLR4 expression is observed in patients with inflammatory bowel disease. However, little is known of the effect of increased TLR4 signaling on intest...

journal_title：Infection and immunity

authors： Dheer R,Santaolalla R,Davies JM,Lang JK,Phillips MC,Pastorini C,Vazquez-Pertejo MT,Abreu MT

更新日期：2016-01-11 00:00:00

abstract：:We developed a porcine dermal explant model to determine the extent to which Staphylococcus aureus biofilm communities deplete oxygen, change pH, and produce damage in underlying tissue. Microelectrode measurements demonstrated that dissolved oxygen (DO) in biofilm-free dermal tissue was 4.45 ± 1.17 mg/liter, while DO...

journal_title：Infection and immunity

authors： Lone AG,Atci E,Renslow R,Beyenal H,Noh S,Fransson B,Abu-Lail N,Park JJ,Gang DR,Call DR

更新日期：2015-06-01 00:00:00

abstract：:Counts of acid-fast bacilli were made on homogenates of whole liver, whole spleen, and two femurs of CBA mice killed at various time intervals after intravenous infection with Mycobacterium lepraemurium. The growth curves so obtained showed that the bacillus multiplied faster in bone marrow than in liver or spleen. No...

journal_title：Infection and immunity

authors： Brown IN,Krenzien HN

更新日期：1976-02-01 00:00:00

abstract：:To determine the ultrastructural distribution and immunological accessibility of proteins II (P.IIs) on the surfaces of whole gonococci, anti-P.II gold probes were developed and used in electron microscopic studies of viable P.II-expressing variants of Neisseria gonorrhoeae FA1090. Anti-P.II probes clearly marked the ...

journal_title：Infection and immunity

authors： Robinson EN Jr,Clemens CM,McGee ZA,Cannon JG

更新日期：1988-04-01 00:00:00

abstract：:Biomaterial-associated infections (BAI), which are predominantly caused by Staphylococcus epidermidis, are a significant problem in modern medicine. Biofilm formation is considered the pivotal element in the pathogenesis, but in previous mouse studies we retrieved S. epidermidis from peri-implant tissue. To assess the...

journal_title：Infection and immunity

authors： Broekhuizen CA,de Boer L,Schipper K,Jones CD,Quadir S,Feldman RG,Dankert J,Vandenbroucke-Grauls CM,Weening JJ,Zaat SA

更新日期：2007-03-01 00:00:00

abstract：:Transcription of the gene encoding the antiphagocytic M protein (emm) of the group A streptococci has been shown to be regulated by CO2 (M. G. Caparon, R. T. Geist, J. Perez-Casal, and J. R. Scott, J. Bacteriol. 174:5693-5701, 1992). We tested the influence of additional environmental growth conditions on emm expressi...

journal_title：Infection and immunity

authors： McIver KS,Heath AS,Scott JR

更新日期：1995-11-01 00:00:00

abstract：:Antibiotics suppressed development of aster yellows (AY) disease symptoms in plants of china aster [Callistephus chinensis (L.) Nees.] and annual chrysanthemum (Chrysanthemum carinatum, Schousb.). When inoculated chrysanthemum plants were treated by any of several techniques with tetracycline antibiotics or chloramphe...

journal_title：Infection and immunity

authors： Davis RE,Whitcomb RF

更新日期：1970-08-01 00:00:00

abstract：:Cryptococcus neoformans NIH 409 was cultured in a defined medium containing D-[1-13C]xylose (Xyl), D-[1-13C]mannose (Man), or D-[1-13C]mannitol as the sole carbon source. The distribution of 13C in the Man, Xyl, glucuronic acid (GlcA), and O-acetyl constituents of native and de-O-acetylated glucuronoxylomannan (GXM) w...

journal_title：Infection and immunity

authors： Cherniak R,O'Neill EB,Sheng S

更新日期：1998-06-01 00:00:00

abstract：:Listeria monocytogenes is an intracellular bacterial pathogen which causes bacteremia and has a tropism for the central nervous system and a propensity to cause maternofetal infection. L. monocytogenes has been shown to be an effective prophylactic and a therapeutic vaccine vector for viral and tumor antigens in anima...

journal_title：Infection and immunity

authors： Angelakopoulos H,Loock K,Sisul DM,Jensen ER,Miller JF,Hohmann EL

更新日期：2002-07-01 00:00:00

abstract：:Ten micrograms of trehalose-6,6' -dimycolate (cord factor) injected into the footpads of mice increased the antibody response to sheep red blood cells (SRBC) subsequently injected into the same sites. There is a relationship between the antibody response and the cellular reaction induced locally and in the draining ly...

journal_title：Infection and immunity

authors： Bekierkunst A,Yarkoni E,Flechner I,Morecki S,Vilkas E,Lederer E

更新日期：1971-09-01 00:00:00

abstract：:Streptococcus pneumoniae is the most frequent microbe causing middle ear infection. The pathophysiology of pneumococcal otitis media has been characterized by measurement of local inflammatory mediators such as inflammatory cells, lysozyme, oxidative metabolic products, and inflammatory cytokines. The role of cytokine...

journal_title：Infection and immunity

authors： Sato K,Liebeler CL,Quartey MK,Le CT,Giebink GS

更新日期：1999-04-01 00:00:00

abstract：:Streptococcus pneumoniae is a frequent colonizer of the upper respiratory tract and a leading cause of bacterial pneumonia. The innate immune system senses pneumococcal cell wall components, toxin, and nucleic acids, which leads to production of inflammatory mediators to initiate and control antibacterial defense. Her...

journal_title：Infection and immunity

authors： Ruiz-Moreno JS,Hamann L,Jin L,Sander LE,Puzianowska-Kuznicka M,Cambier J,Witzenrath M,Schumann RR,Suttorp N,Opitz B

更新日期：2018-02-20 00:00:00

abstract：:Burkholderia pseudomallei is a Gram-negative rod and the causative agent of melioidosis, an emerging infectious disease of tropical and subtropical areas worldwide. B. pseudomallei harbors a remarkable number of virulence factors, including six type VI secretion systems (T6SS). Using our previously described plaque as...

journal_title：Infection and immunity

authors： Hopf V,Göhler A,Eske-Pogodda K,Bast A,Steinmetz I,Breitbach K

更新日期：2014-05-01 00:00:00

abstract：:Escherichia coli heat-stable enterotoxin (ST) binds to receptors on rat intestinal cells and brush border membranes (BBM). We devised experiments to examine the reversibility of ST binding. We found that both 125I-labeled ST and native ST were spontaneously dissociable from the BBM receptor. Radiolabeled ST bound to B...

journal_title：Infection and immunity

authors： Cohen MB,Thompson MR,Overmann GJ,Giannella RA

更新日期：1987-02-01 00:00:00

abstract：:Porphyromonas gingivalis, a periodontopathic bacterium, is known to invade oral epithelial cells in periodontal lesions, although the mechanism is unclear. In the present study, goat polyclonal anti-intercellular adhesion molecule 1 (anti-ICAM-1) antibody inhibited the invasion of P. gingivalis into KB cells (human or...

journal_title：Infection and immunity

authors： Tamai R,Asai Y,Ogawa T

更新日期：2005-10-01 00:00:00

abstract：:Clostridium perfringens enterotoxin is the major virulence factor involved in the pathogenesis of C. perfringens type A food poisoning and several non-food-borne human gastrointestinal illnesses. The enterotoxin gene, cpe, is located on the chromosome of food-poisoning isolates but is found on a large plasmid in non-f...

journal_title：Infection and immunity

authors： Brynestad S,Sarker MR,McClane BA,Granum PE,Rood JI

更新日期：2001-05-01 00:00:00