Effect of pretreatment with Mycobacterium bovis (strain BCG) and immune syphilitic serum on rabbit resistance to Treponema pallidum.

abstract：:Bacillus anthracis, the causal agent of anthrax, synthesizes two surface layer (S-layer) proteins, EA1 and Sap, which account for 5 to 10% of total protein and are expressed in vivo. A recombinant B. anthracis strain was constructed by integrating into the chromosome a translational fusion harboring the DNA fragments ...

journal_title：Infection and immunity

authors： Mesnage S,Weber-Levy M,Haustant M,Mock M,Fouet A

更新日期：1999-09-01 00:00:00

abstract：:Recent work has demonstrated that the polyketide natural product Aurodox from Streptomyces goldiniensis is able to block the pathogenesis of the murine pathogen Citrobacter rodentium In this work, we aimed to gain a better understanding of the mechanism of action of the compound. We show that Aurodox downregulates the...

journal_title：Infection and immunity

authors： McHugh RE,O'Boyle N,Connolly JPR,Hoskisson PA,Roe AJ

更新日期：2019-01-24 00:00:00

abstract：:To characterize the roles of Porphyromonas gingivalis and its components in disease processes, we investigated the cytokine profiles induced by live P. gingivalis, its lipopolysaccharide (LPS), and its major fimbrial protein, fimbrillin (FimA). A cytokine antibody array revealed that human monocyte-derived macrophages...

journal_title：Infection and immunity

authors： Zhou Q,Amar S

更新日期：2006-02-01 00:00:00

abstract：:The purpose of the present study was to analyze Chlamydia pneumoniae-induced, antigen-specific, cell-mediated immunity. Peripheral blood mononuclear cells of four persons infected with C. pneumoniae Kajaani 6 and 17 healthy volunteers were stimulated with antigen composed of whole elementary bodies of C. pneumoniae Ka...

journal_title：Infection and immunity

authors： Surcel HM,Syrjälä H,Leinonen M,Saikku P,Herva E

更新日期：1993-05-01 00:00:00

abstract：:The membrane-damaging properties on human diploid embryonic lung fibroblasts of streptolysin O (from Streptococcus pyogenes) and theta-toxin (from Clostridium perfringens) were compared. The results are consistent with the suggested mechanism for hemolysis by streptolysin O involving one fixation site and one lytic si...

journal_title：Infection and immunity

authors： Thelestam M,Möllby R

更新日期：1980-09-01 00:00:00

abstract：:A heterogeneous subset of extraintestinal pathogenic Escherichia coli (ExPEC) strains, referred to as uropathogenic E. coli (UPEC), causes most uncomplicated urinary tract infections. However, no core set of virulence factors exists among UPEC strains. Instead, the focus of the analysis of urovirulence has shifted to ...

journal_title：Infection and immunity

authors： Engstrom MD,Alteri CJ,Mobley HL

更新日期：2014-09-01 00:00:00

abstract：:The development of chronic pathology in mice at 2 to 10 months after inoculation of 10(2) T. cruzi trypomastigotes can be prevented by preimmunization with live, attenuated culture parasites (strain TCC). Swiss mice received one or three immunizing inoculations of 10(6) TCC organisms and were challenged with 10(2) Tul...

journal_title：Infection and immunity

authors： Basombrío MA,Besuschio S

更新日期：1982-04-01 00:00:00

abstract：:A solid-phase radioimmunoassay method has been developed for the detection of rotavirus in the form of a purified antigen and in stool. The parameters of the radioimmunoassay were examined and optimized to give high sensitivity and same-day results. Compared with electron microscopy, the assay is up to 10 times as sen...

journal_title：Infection and immunity

authors： Middleton PJ,Holdaway MD,Petric M,Szymanski MT,Tam JS

更新日期：1977-05-01 00:00:00

abstract：:While gamma/delta T cells are involved in host defense and immunopathology in a variety of infectious diseases, their precise role is not yet clearly defined. In the absence of gamma/delta T cells, mice die after infection with a dose of Listeria monocytogenes that is not lethal in immunologically intact animals. Morb...

journal_title：Infection and immunity

authors： Skeen MJ,Rix EP,Freeman MM,Ziegler HK

更新日期：2001-12-01 00:00:00

abstract：:Salmonella enterica serovar Enteritidis (S. Enteritidis) is a major etiologic agent of nontyphoid salmonellosis in the United States. S. Enteritidis persistently and silently colonizes the intestinal and reproductive tract of laying hens, resulting in contaminated poultry products. The consumption of contaminated poul...

journal_title：Infection and immunity

authors： McKelvey JA,Yang M,Jiang Y,Zhang S

更新日期：2014-12-01 00:00:00

abstract：:Mice were infected with Chlamydia trachomatis (L2/434) and at various intervals after infection their lymphoid cells were tested directly for cytotoxic activity against Chlamydia-infected L929 cells. In a modified cell-mediated lympholysis assay, splenic, lymph node, and peritoneal exudate cells did not significantly ...

journal_title：Infection and immunity

authors： Pavia CS,Schachter J

更新日期：1983-03-01 00:00:00

abstract：:Dendritic cells (DC) suffer a maturation defect following interaction with erythrocytes infected with malaria parasites and become unable to induce protective malaria liver-stage immunity. Here we show that, by contrast, maturation-arrested DC in vitro are capable of the successful induction of antigen-specific gamma ...

journal_title：Infection and immunity

authors： Pouniotis DS,Proudfoot O,Bogdanoska V,Apostolopoulos V,Fifis T,Plebanski M

更新日期：2004-09-01 00:00:00

abstract：:The effect of human-specific antibody on surface membrane antigens of trypomastigotes of Trypanosoma cruzi was studied in vitro by using immunofluorescence methods. Immune sera induced aggregation of surface antigens in trypomastigotes to form polar cell caps. ...

journal_title：Infection and immunity

authors： Schmuñis GA,Szarfman A,Langembach T,de Souza W

更新日期：1978-05-01 00:00:00

abstract：:Streptococcus equi and Streptococcus zooepidemicus are major etiological agents of upper and lower airway disease in horses. Despite the considerable animal suffering and economic burden associated with these diseases, the factors that contribute to the virulence of these equine pathogens have not been extensively inv...

journal_title：Infection and immunity

authors： Harrington DJ,Greated JS,Chanter N,Sutcliffe IC

更新日期：2000-10-01 00:00:00

abstract：:Mesophilic Aeromonas hydrophila strains of serotype O34 typically express smooth lipopolysaccharide (LPS) on their surface. A single mutation in the gene that codes for UDP N-acetylgalactosamine 4-epimerase (gne) confers the O(-) phenotype (LPS without O-antigen molecules) on a strain in serotypes O18 and O34, but not...

journal_title：Infection and immunity

authors： Canals R,Jiménez N,Vilches S,Regué M,Merino S,Tomás JM

更新日期：2006-01-01 00:00:00

abstract：:Staphylococcus aureus experimental endocarditis relies on sequential fibrinogen binding (for valve colonization) and fibronectin binding (for endothelial invasion) conferred by peptidoglycan-attached adhesins. Fibronectin-binding protein A (FnBPA) reconciles these two properties--as well as elastin binding--and promot...

journal_title：Infection and immunity

authors： Piroth L,Que YA,Widmer E,Panchaud A,Piu S,Entenza JM,Moreillon P

更新日期：2008-08-01 00:00:00

abstract：:Thirty-two clinical isolates of Shiga-like toxin (SLT)-producing Escherichia coli associated with single cases or outbreaks of bloody diarrhea, hemorrhagic colitis, the hemolytic uremic syndrome, or edema disease of swine were examined for multiple copies of genes belonging to the slt-I or slt-II toxin families. Five ...

journal_title：Infection and immunity

authors： Schmitt CK,McKee ML,O'Brien AD

更新日期：1991-03-01 00:00:00

abstract：:In studies of experimental Lyme disease, a major obstacle has been the unavailability of a suitable animal model. We found that irradiated LSH/Ss Lak hamsters developed arthritis after injection of Borrelia burgdorferi in the hind paws. When nonirradiated hamsters were injected in the hind paws with B. burgdorferi, ac...

journal_title：Infection and immunity

authors： Schmitz JL,Schell RF,Hejka A,England DM,Konick L

更新日期：1988-09-01 00:00:00

abstract：:P.69 pertactin (P.69 Prn), an adhesion molecule from the causative agent of pertussis, Bordetella pertussis, is present in cellular and most acellular vaccines that are currently used worldwide. Although both humoral immunity and cellular immunity directed against P.69 Prn have been implicated in protective immune mec...

journal_title：Infection and immunity

authors： Stenger RM,Poelen MC,Moret EE,Kuipers B,Bruijns SC,Hoogerhout P,Hijnen M,King AJ,Mooi FR,Boog CJ,van Els CA

更新日期：2009-02-01 00:00:00

abstract：:A clone expressing a 58-kDa protein reactive with human convalescent-phase serum was isolated from a recombinant library of Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis. Sequencing identified two open reading frames, one encoding a 10.3-kDa polypeptide consisting of 94 amino acids and another encod...

journal_title：Infection and immunity

authors： Sumner JW,Sims KG,Jones DC,Anderson BE

更新日期：1993-08-01 00:00:00

abstract：:We previously demonstrated the suppression of cell-mediated immunity to Listeria monocytogenes by Pseudomonas aeruginosa-induced, macrophage-like cells. The present study was undertaken to evaluate the mechanism for this suppression. P. aeruginosa supernatant was shown to activate macrophages by the criteria of increa...

journal_title：Infection and immunity

authors： Petit JC,Richard G,Burghoffer B,Daguet GL

更新日期：1985-08-01 00:00:00

abstract：:Experiments were performed to study the effect of antibody to Streptococcus mutans glucosyltransferase (GTF) on the implantation of these organisms in hamsters. Salivary (immunoglobulin A) and serum (immunoglobulin G) antibodies to GTF and GTF-inhibiting activity were elicited by injection of GTF in Freund complete ad...

journal_title：Infection and immunity

authors： Smith DJ,Taubman MA,Ebersole JL

更新日期：1982-08-01 00:00:00

abstract：:Lipoprotein I (OprI) is one of the major proteins of the outer membrane of Pseudomonas aeruginosa. OprI is a candidate for a vaccine against P. aeruginosa, because it cross-reacts antigenically in all serotype strains of the International Antigenic Typing Scheme. We recently cloned and expressed the gene coding for Op...

journal_title：Infection and immunity

authors： Finke M,Duchêne M,Eckhardt A,Domdey H,von Specht BU

更新日期：1990-07-01 00:00:00

abstract：:Genetic diversity and relationships among 109 isolates of Neisseria meningitidis obtained from throat cultures of healthy individuals in Norway in 1984 were assessed by analyzing electrophoretically demonstrable allelic variation at 15 enzyme-encoding chromosomal genes. Seventy-eight distinctive electrophoretic types ...

journal_title：Infection and immunity

authors： Caugant DA,Kristiansen BE,Frøholm LO,Bøvre K,Selander RK

更新日期：1988-08-01 00:00:00

abstract：:To evaluate the enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides, the rate of isolation of these organisms was compared among individuals with and without diarrhea in Thailand. In two groups of American travelers, A. hydrophila, but not P. shigelloides, was associated with episodes of travelers...

journal_title：Infection and immunity

authors： Pitarangsi C,Echeverria P,Whitmire R,Tirapat C,Formal S,Dammin GJ,Tingtalapong M

更新日期：1982-02-01 00:00:00

abstract：:In malarial infections of primates, the spleen has been shown to modulate parasite antigen expression on the surfaces of infected erythrocytes. The processes affected include cytoadherence, which is central to the pathophysiology of severe falciparum malaria, and the related phenomenon of rosette formation. In this st...

journal_title：Infection and immunity

authors： Ho M,Bannister LH,Looareesuwan S,Suntharasamai P

更新日期：1992-06-01 00:00:00

abstract：:We determined the diphtheria toxin phenotype of specially selected isolates of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis (C. ovis). All produced proteins similar in size and immunological structure to diphtheria toxin. As with diphtheria toxin, they exhibited ADP-ribosylating activity, and their ...

journal_title：Infection and immunity

authors： Wong TP,Groman N

更新日期：1984-03-01 00:00:00

abstract：:The present study was performed to determine whether Histoplasma capsulatum (yeast phase) is able to activate the alternative complement pathway. H. capsulatum yeasts were shown to consume C3 in C4-deficient guinea pig serum. Immunoelectrophoretic conversion of alternative pathway component factor B confirmed that C3 ...

journal_title：Infection and immunity

authors： Ratnoff WD,Pepple JM,Winkelstein JA

更新日期：1980-10-01 00:00:00

abstract：:A procedure was developed to purify dermonecrotic toxin (DNT) from a sonic extract of a serotype D strain of Pasteurella multocida. Sonic extract containing DNT was applied to a DEAE-Sephacel column and eluted by a linear gradient of NaCl. Upon rechromatographing, fractions with dermonecrotic activity for guinea pigs ...

journal_title：Infection and immunity

authors： Nakai T,Sawata A,Tsuji M,Samejima Y,Kume K

更新日期：1984-11-01 00:00:00

abstract：:The kinetics of infection and the pathogenic effects on the reproductive function of laboratory mice infected with Bartonella birtlesii recovered from an Apodemus species are described. B. birtlesii infection, as determined by bacteremia, occurred in BALB/c mice inoculated intravenously. Inoculation with a low-dose in...

journal_title：Infection and immunity

authors： Boulouis HJ,Barrat F,Bermond D,Bernex F,Thibault D,Heller R,Fontaine JJ,Piémont Y,Chomel BB

更新日期：2001-09-01 00:00:00