Inhibitory effects of protamines on proteolytic and adhesive activities of Porphyromonas gingivalis.

abstract：:In this report, we demonstrate that the variable antigens present on the surface of Plasmodium knowlesi-infected erythrocytes could not be found on the surface of merozoites. A number of technical problems had to be solved to make such a comparative study possible, including the purification of merozoites by affinity ...

journal_title：Infection and immunity

authors： Hommel M,David PH

更新日期：1981-07-01 00:00:00

abstract：:Infection with mycobacterial species, including Mycobacterium tuberculosis, has long been implicated in the etiopathology of rheumatoid arthritis (RA) on the basis of clinical and pathological similarities between tuberculosis and RA. Despite evidence of immune responses to mycobacterial antigens in RA patient synovia...

journal_title：Infection and immunity

authors： Kempsell KE,Cox CJ,McColm AA,Bagshaw JA,Reece R,Veale DJ,Emery P,Isaacs JD,Gaston JS,Crowe JS

更新日期：2001-03-01 00:00:00

abstract：:Inner ear dysfunction secondary to chronic otitis media (OM), including high-frequency sensorineural hearing loss or vertigo, is not uncommon. Although chronic middle ear inflammation is believed to cause inner ear dysfunction by entry of OM pathogen components or cytokines from the middle ear into the inner ear, the ...

journal_title：Infection and immunity

authors： Moon SK,Woo JI,Lee HY,Park R,Shimada J,Pan H,Gellibolian R,Lim DJ

更新日期：2007-07-01 00:00:00

abstract：:Previous studies demonstrated that Mycoplasma arthritidis strain 158 acquired a high degree of virulence upon lysogenization with bacteriophage MAV1. In the present study, the association between MAV1 and virulence was reexamined by creating new lysogens of 158 and of a relatively avirulent mutant, strain 158-1. In th...

journal_title：Infection and immunity

authors： Clapper B,Tu AH,Simmons WL,Dybvig K

更新日期：2004-12-01 00:00:00

abstract：:Seven antigens of Borrelia hermsii, B. parkeri, and B. turicatae with isoelectric points in the range of 4.4 to 5.0 and molecular masses of 40 to 43 kilodaltons played a role in the relapse phenomenon of relapsing fever. Based upon location of the antigens in the outer envelope, the molecular weight, and Western blot ...

journal_title：Infection and immunity

authors： Kehl KS,Farmer SG,Komorowski RA,Knox KK

更新日期：1986-12-01 00:00:00

abstract：:Conditions are described for the production of an extracellular cytotoxin or CHO cell-killing factor by Vibrio fluvialis, a recently recognized enteric pathogen. The cell-killing factor was ammonium sulfate precipitable, heat labile, and inactivated by proteases, and had an isoelectric point (estimated by sucrose dens...

journal_title：Infection and immunity

authors： Wall VW,Kreger AS,Richardson SH

更新日期：1984-12-01 00:00:00

abstract：:Staphylococcal enterotoxins A through D (SEA through SED) and toxic shock syndrome toxin-1 display superantigen properties, i.e., they stimulate a great fraction of T cells expressing certain T-cell receptor V beta sequences. Using a newly established rat model of septic Staphylococcus aureus arthritis, we have recent...

journal_title：Infection and immunity

authors： Bremell T,Tarkowski A

更新日期：1995-10-01 00:00:00

abstract：:Forty-seven bacterial strains representing four different group C streptococcal species were tested for binding of human and bovine immunoglobulin G (IgG) subclasses. Specific binding sites for IgG were found in all bacterial species studied. The four species included differed, however, in their capacities to interact...

journal_title：Infection and immunity

authors： Myhre EB,Kronvall G

更新日期：1980-03-01 00:00:00

abstract：:The search to identify Mycobacterium tuberculosis antigens capable of conferring protective immunity against tuberculosis has received a boost owing to the resurgence of tuberculosis over the past two decades. It has long been recognized that lymphoid cells are required for protection against M. tuberculosis. While tr...

journal_title：Infection and immunity

authors： Kumar P,Amara RR,Challu VK,Chadda VK,Satchidanandam V

更新日期：2003-04-01 00:00:00

abstract：:One aspect in a broad spectrum of possible mechanisms of cariostatic reactions of fluoride is its interaction with the metabolism of oral bacteria. Information on the mechanisms and kinetics of fluoride inhibition of essential enzymes of the glycolytic pathway of the relevant bacteria is lacking. In this work, the iso...

journal_title：Infection and immunity

authors： Hüther FJ,Psarros N,Duschner H

更新日期：1990-04-01 00:00:00

abstract：:Analysis of the specificity of bactericidal antibodies in normal, convalescent, and postvaccination human sera is important in understanding human immunity to meningococcal infections and can aid in the design of an effective group B vaccine. A collection of human sera, including group C and group B convalescent-phase...

journal_title：Infection and immunity

authors： Schmiel DH,Moran EE,Keiser PB,Brandt BL,Zollinger WD

更新日期：2011-10-01 00:00:00

abstract：:Protective immunity against pulmonary tuberculosis (TB) is characterized by the formation in the lungs of granulomas consisting of macrophages and activated T cells producing tumor necrosis factor alpha and gamma interferon, both required for the activation of the phagocytes. In 90% of immunocompetent humans, this res...

journal_title：Infection and immunity

authors： Kaplan G,Post FA,Moreira AL,Wainwright H,Kreiswirth BN,Tanverdi M,Mathema B,Ramaswamy SV,Walther G,Steyn LM,Barry CE 3rd,Bekker LG

更新日期：2003-12-01 00:00:00

abstract：:The surface antigen makeup of metacyclic trypomastigote forms of strain G of Trypanosoma cruzi, which produce a subpatent infection in mice, differed from those of the virulent strains Y and CL. A 100,000-molecular-weight protein, barely detectable on the Y or CL cell surface, appeared as the main surface antigen of t...

journal_title：Infection and immunity

authors： Yoshida N

更新日期：1983-05-01 00:00:00

abstract：:Mannan (MAN) extracted from Candida albicans 20A was investigated for its potential as an antigen in the detection of cell-mediated immunity (CMI) in vivo and in vitro and for its ability to modulate CMI when administered intravenously (i.v.). CBA/J mice were either immunized as adults by the cutaneous inoculation of ...

journal_title：Infection and immunity

authors： Domer JE,Garner RE,Befidi-Mengue RN

更新日期：1989-03-01 00:00:00

abstract：:We have investigated the roles of gamma interferon (IFN-gamma) and interleukin-4 (IL-4) in host defense against Brugia malayi. Our data suggest that the lack of either IFN-gamma or IL-4 prolongs the time required to achieve sterile immunity, suggesting that both canonical type 1 and type 2 responses are involved in th...

journal_title：Infection and immunity

authors： Babu S,Ganley LM,Klei TR,Shultz LD,Rajan TV

更新日期：2000-05-01 00:00:00

abstract：:Anaplasma phagocytophilum is an obligate intracellular bacterium that infects myeloid cells in the mammalian host. Msp2 (p44) is the major immunodominant outer-membrane protein of these bacteria. We hypothesized that Msp2 acts as an adhesin for A. phagocytophilum entry into granulocytes. This potential role was invest...

journal_title：Infection and immunity

authors： Park J,Choi KS,Dumler JS

更新日期：2003-07-01 00:00:00

abstract：:Based upon the lipopolysaccharide (LPS) structure and antigenicity of Shigella group B, a strategy for broad cross-protection against 14 Shigella flexneri serotypes was designed. This strategy involves the use of two S. flexneri serotypes (2a and 3a), which together bear the all of the major antigenic group factors of...

journal_title：Infection and immunity

authors： Noriega FR,Liao FM,Maneval DR,Ren S,Formal SB,Levine MM

更新日期：1999-02-01 00:00:00

abstract：:Staphylococcus aureus is an important opportunistic pathogen and is the etiological agent of many hospital- and community-acquired infections. The golden pigment, staphyloxanthin, of S. aureus colonies distinguishes it from other staphylococci and related Gram-positive cocci. Staphyloxanthin is the product of a series...

journal_title：Infection and immunity

authors： Hall JW,Yang J,Guo H,Ji Y

更新日期：2017-01-26 00:00:00

abstract：:The ability of oral immunization to interfere with the establishment of infection with Helicobacter felis was examined. Groups of Swiss Webster mice were immunized orally with 250 micrograms of Helicobacter pylori recombinant urease (rUrease) and 10 micrograms of cholera toxin (CT) adjuvant, 1 mg of H. felis sonicate ...

journal_title：Infection and immunity

authors： Pappo J,Thomas WD Jr,Kabok Z,Taylor NS,Murphy JC,Fox JG

更新日期：1995-04-01 00:00:00

abstract：:Calprotectin, an S100 calcium-binding protein with broad-spectrum antimicrobial activity in vitro, is expressed in neutrophils, monocytes, and gingival keratinocytes. In periodontitis, calprotectin appears upregulated and is detected at higher levels in gingival crevicular fluid and tissue specimens. How calprotectin ...

journal_title：Infection and immunity

authors： Nisapakultorn K,Ross KF,Herzberg MC

更新日期：2001-07-01 00:00:00

abstract：:The Pseudomonas aeruginosa quorum-sensing systems, las and rhl, control the production of numerous virulence factors. In this study, we have used the burned-mouse model to examine the contribution of quorum-sensing systems to the pathogenesis of P. aeruginosa infections in burn wounds. Different quorum-sensing mutants...

journal_title：Infection and immunity

authors： Rumbaugh KP,Griswold JA,Iglewski BH,Hamood AN

更新日期：1999-11-01 00:00:00

abstract：:The roles of different ribonucleotide reductases (RNRs) in bacterial pathogenesis have not been studied systematically. In this work we analyzed the importance of the different Pseudomonas aeruginosa RNRs in pathogenesis using the Drosophila melanogaster host-pathogen interaction model. P. aeruginosa codes for three d...

journal_title：Infection and immunity

authors： Sjöberg BM,Torrents E

更新日期：2011-07-01 00:00:00

abstract：:Immunoprecipitation of radiolabeled antigens with bovine antisera indicated that many Babesia bigemina and Babesia bovis merozoite proteins contain isolate-common epitopes, while at least 16 B. bigemina and 8 B. bovis proteins contain species-cross-reactive epitopes. One immunogenic, isolate-common, and species-specif...

journal_title：Infection and immunity

authors： McElwain TF,Palmer GH,Goff WL,McGuire TC

更新日期：1988-06-01 00:00:00

abstract：:Monoclonal antibodies were raised against a bactericidal protein fraction that was purified from an extract of bovine neutrophil granules and that was previously shown (A. Savoini, R. Marzari, L. Dolzani, D. Serranò, G. Graziosi, R. Gennaro, and D. Romeo, Antimicrob. Agents Chemother. 26:405-407, 1984) to inhibit bact...

journal_title：Infection and immunity

authors： Marzari R,Scaggiante B,Skerlavaj B,Bittolo M,Gennaro R,Romeo D

更新日期：1988-08-01 00:00:00

abstract：:We have previously identified two K88ac adhesion receptors (210 and 240 kDa) which are present in membrane preparations from adhesive but not nonadhesive porcine intestinal brush border cells; these adhesin receptors are postulated to be important determinants of the susceptibility of pigs to K88ac+ enterotoxigenic Es...

journal_title：Infection and immunity

authors： Erickson AK,Baker DR,Bosworth BT,Casey TA,Benfield DA,Francis DH

更新日期：1994-12-01 00:00:00

abstract：:The development of immunoglobulin-containing cells and antigen-specific plasma cells in retropharyngeal and bronchial lymph nodes, in lung tissue, and in nasal mucous membrane was followed during an experimental infection of pigs with Mycoplasma hyopneumoniae. An enzyme-linked immunosorbent assay was used to follow st...

journal_title：Infection and immunity

authors： Suter M,Kobisch M,Nicolet J

更新日期：1985-09-01 00:00:00

abstract：:Previous studies have demonstrated antigenic differences among the pili expressed by various strains of Haemophilus influenzae type b (Hib). In order to understand the molecular basis for these differences, the structural gene for pilin was cloned from Hib strain Eagan (p+) and the nucleotide sequence was compared to ...

journal_title：Infection and immunity

authors： Forney LJ,Marrs CF,Bektesh SL,Gilsdorf JR

更新日期：1991-06-01 00:00:00

abstract：:Staphylococcus aureus is an important pathogen of humans and other animals, causing bacteremia, abscesses, endocarditis, and other infectious syndromes. A signature-tagged mutagenesis (STM) system was adapted for use in studying the genes required for in vivo survival of S. aureus. An STM library was ultimately create...

journal_title：Infection and immunity

authors： Schwan WR,Coulter SN,Ng EY,Langhorne MH,Ritchie HD,Brody LL,Westbrock-Wadman S,Bayer AS,Folger KR,Stover CK

更新日期：1998-02-01 00:00:00

abstract：:Clostridium difficile toxins A and B (TcdA and TcdB) are the causative agents of antibiotic-associated pseudomembranous colitis. Mucosal mast cells play a crucial role in the inflammatory processes underlying this disease. We studied the direct effects of TcdA and TcdB on the human mast cell line HMC-1 with respect to...

journal_title：Infection and immunity

authors： Meyer GK,Neetz A,Brandes G,Tsikas D,Butterfield JH,Just I,Gerhard R

更新日期：2007-08-01 00:00:00

abstract：:The action of injected bacterial lipopolysaccharide upon the uptake of cytophilic antibodies by macrophages was found to be unrelated either to changes in surface charge or to the rate of anaerobic glycolysis of these cells. It is apparently mediated by alterations in the levels of material in the serum which enhances...

journal_title：Infection and immunity

authors： Tizard IR

更新日期：1971-10-01 00:00:00