Abstract:
:Deciphering the mechanisms by which Borrelia burgdorferi controls the synthesis of proteins associated with mammalian infection will be an important step toward understanding the pathogenic properties of Lyme disease-causing bacteria. We present results of studies indicating that B. burgdorferi senses a wide variety of environmental stimuli, including soluble chemicals, which enables it to independently control synthesis of the Erp and OspC proteins. Regulation of OspC and Erp expression appears to occur at the level of transcription. In this regard, we observed that one or more DNA-binding proteins interact specifically with erp promoter DNA but not with the ospC promoter.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Babb K,El-Hage N,Miller JC,Carroll JA,Stevenson Bdoi
10.1128/IAI.69.6.4146-4153.2001keywords:
subject
Has Abstractpub_date
2001-06-01 00:00:00pages
4146-53issue
6eissn
0019-9567issn
1098-5522journal_volume
69pub_type
杂志文章abstract::Apical membrane antigen 1 (AMA1) is expressed on the surfaces of Plasmodium falciparum merozoites and is thought to play an important role in the invasion of erythrocytes by malaria parasites. To select for peptides that mimic conformational B-cell epitopes on AMA1, we screened a phage display library of >10(8) indivi...
journal_title:Infection and immunity
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更新日期:2004-02-01 00:00:00
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journal_title:Infection and immunity
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更新日期:1991-09-01 00:00:00
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更新日期:1989-12-01 00:00:00
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journal_title:Infection and immunity
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更新日期:2017-09-20 00:00:00
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更新日期:1994-04-01 00:00:00
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journal_title:Infection and immunity
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doi:
更新日期:1999-12-01 00:00:00
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journal_title:Infection and immunity
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更新日期:1976-05-01 00:00:00
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更新日期:2020-12-15 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:1985-09-01 00:00:00
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journal_title:Infection and immunity
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更新日期:2000-07-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.64.4.1140-1145.1996
更新日期:1996-04-01 00:00:00
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更新日期:2012-04-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.35.3.800-808.1982
更新日期:1982-03-01 00:00:00
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journal_title:Infection and immunity
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更新日期:2003-08-01 00:00:00
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更新日期:2011-07-01 00:00:00
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journal_title:Infection and immunity
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doi:10.1128/IAI.14.1.95-99.1976
更新日期:1976-07-01 00:00:00
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journal_title:Infection and immunity
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更新日期:1990-03-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.33.1.130-135.1981
更新日期:1981-07-01 00:00:00
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journal_title:Infection and immunity
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更新日期:1984-06-01 00:00:00
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journal_title:Infection and immunity
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doi:10.1128/IAI.32.2.681-689.1981
更新日期:1981-05-01 00:00:00
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journal_title:Infection and immunity
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更新日期:1979-07-01 00:00:00
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journal_title:Infection and immunity
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更新日期:1996-06-01 00:00:00
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更新日期:1981-04-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:1992-08-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:1974-11-01 00:00:00