Recombinant 56-kilodalton major outer membrane protein antigen of Orientia tsutsugamushi Shanxi and its antigenicity.

abstract：:We used an in vitro opsonophagocytic killing assay to measure the functional activity of antibody directed at the mucoid exopolysaccharide (MEP) antigen expressed by Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. Rabbit antibodies raised to purified MEP were able to mediate phagocytic killing i...

journal_title：Infection and immunity

authors： Ames P,DesJardins D,Pier GB

更新日期：1985-08-01 00:00:00

abstract：:Saccharomyces boulardii is a nonpathogenic yeast used in the treatment of Clostridium difficile diarrhea and colitis. We have reported that S. boulardii inhibits C. difficile toxin A enteritis in rats by releasing a 54-kDa protease which digests the toxin A molecule and its brush border membrane (BBM) receptor (I. Cas...

journal_title：Infection and immunity

authors： Castagliuolo I,Riegler MF,Valenick L,LaMont JT,Pothoulakis C

更新日期：1999-01-01 00:00:00

abstract：:Infection of L cells with Chlamydia psittaci inhibited the burst of deoxyribonucleic acid synthesis that occurs when the host cells are released from a double thymidine block. ...

journal_title：Infection and immunity

authors： Tribby II,Moulder JW

更新日期：1971-02-01 00:00:00

abstract：:The protozoan parasite Cryptosporidium parvum is a significant cause of diarrheal disease worldwide. Attachment to and invasion of host intestinal epithelial cells by C. parvum sporozoites are crucial steps in the pathogenesis of cryptosporidiosis. The molecular basis of these initial interactions is unknown. In order...

journal_title：Infection and immunity

authors： Cevallos AM,Bhat N,Verdon R,Hamer DH,Stein B,Tzipori S,Pereira ME,Keusch GT,Ward HD

更新日期：2000-09-01 00:00:00

abstract：:The skin microenvironment at the site of infection plays a role in the early events that determine protective T helper 1/type 1 immune responses during cutaneous leishmaniasis (CL) infection. During CL in nonhealing BALB/c mice, early interleukin-4 (IL-4) can instruct dendritic cells for protective Th1 immunity. Addit...

journal_title：Infection and immunity

authors： Govender M,Hurdayal R,Martinez-Salazar B,Gqada K,Pillay S,Gcanga L,Passelli K,Nieuwenhuizen NE,Tacchini-Cottier F,Guler R,Brombacher F

更新日期：2018-11-20 00:00:00

abstract：:Pools of rat antiserum to Plasmodium berghei had different levels of protective activity as assessed by a passive transfer test. Preincubation of parasite inocula with an effective pool before injection did not significantly enhance protective activity. Removal of the antiserum from preincubated parasite inocula aboli...

journal_title：Infection and immunity

authors： Brown IN,Phillips RS

更新日期：1974-12-01 00:00:00

abstract：:Western blot (immunoblot) analysis of sera from cattle vaccinated with Brucella abortus S19 exhibit an elevated serologic response to Hsp62, the GroEL homolog (BaGroEL). Serologic screening of individual cows vaccinated with B. abortus S19 revealed no correlation between the immune response to BaGroEL and protection a...

journal_title：Infection and immunity

authors： Lin J,Adams LG,Ficht TA

更新日期：1996-10-01 00:00:00

abstract：:One aspect in a broad spectrum of possible mechanisms of cariostatic reactions of fluoride is its interaction with the metabolism of oral bacteria. Information on the mechanisms and kinetics of fluoride inhibition of essential enzymes of the glycolytic pathway of the relevant bacteria is lacking. In this work, the iso...

journal_title：Infection and immunity

authors： Hüther FJ,Psarros N,Duschner H

更新日期：1990-04-01 00:00:00

abstract：:Iron is limiting in the human host, and bacterial pathogens respond to this environment by regulating gene expression through the ferric uptake regulator protein (Fur). In vitro studies have demonstrated that Neisseria gonorrhoeae controls the expression of several critical genes through an iron- and Fur-mediated mech...

journal_title：Infection and immunity

authors： Agarwal S,King CA,Klein EK,Soper DE,Rice PA,Wetzler LM,Genco CA

更新日期：2005-07-01 00:00:00

abstract：:To study the immunological activity of proteins secreted by Mycobacterium tuberculosis, we carried out comparative studies in guinea pigs infected intravenously with 2.5 x 10(3) CFU of this organism or with 2.5 x 10(4) CFU of Mycobacterium bovis BCG. Groups of infected guinea pigs were skin tested with fractions of se...

journal_title：Infection and immunity

authors： Hasløv K,Andersen A,Nagai S,Gottschau A,Sørensen T,Andersen P

更新日期：1995-03-01 00:00:00

abstract：:Groups of mice were immunized either subcutaneously or intranasally with purified Brucella melitensis lipopolysaccharide (LPS) or with LPS as a noncovalent complex with Neisseria meningitidis group B outer membrane protein (LPS-GBOMP). Control mice were inoculated with sterile saline. Two doses of vaccine were given 4...

journal_title：Infection and immunity

authors： Bhattacharjee AK,Izadjoo MJ,Zollinger WD,Nikolich MP,Hoover DL

更新日期：2006-10-01 00:00:00

abstract：:The affinity of uropathogenic Escherichia coli to kidneys and bladders of experimentally infected mice was shown to be determined in part by the adhesive properties of the infecting bacteria. Mice were infected with various pairwise combinations of two homogeneic sets of bacteria: (i) mutants derived from a human pyel...

journal_title：Infection and immunity

authors： Hagberg L,Hull R,Hull S,Falkow S,Freter R,Svanborg Edén C

更新日期：1983-04-01 00:00:00

abstract：:Cholera enterotoxin and the related heat-labile enterotoxins of Escherichia coli enter their target cells through noncoated vesicles, but how the toxins are processed intracellularly and how they get to their targeted enzyme, adenylate cyclase, remain to be defined. Brefeldin A, an inhibitor of the trans-Golgi network...

journal_title：Infection and immunity

authors： Donta ST,Beristain S,Tomicic TK

更新日期：1993-08-01 00:00:00

abstract：:Interactions between Yersinia enterocolitica and rabbit ileal mucus were examined. Strains carrying the Yersinia virulence plasmid, pYV, adhered to crude mucus but not to intestinal luminal contents that had been immobilized on polystyrene. Using an Y. enterocolitica O:9 mutant in which the yadA gene (formerly called ...

journal_title：Infection and immunity

authors： Paerregaard A,Espersen F,Jensen OM,Skurnik M

更新日期：1991-01-01 00:00:00

abstract：:We report the immunizing capacity of Salmonella enteritidis AL1192, a strain that has been cured of a 36-megadalton plasmid, to protect ddY mice against subsequent challenge with virulent salmonellas. This strain, which was given subcutaneously at a dose of 10(6) organisms, provided significant protection against oral...

journal_title：Infection and immunity

authors： Nakamura M,Sato S,Ohya T,Suzuki S,Ikeda S,Koeda T

更新日期：1985-11-01 00:00:00

abstract：:Intracellular survival of Chlamydia psittaci is in part dependent on the ability of the organism to thwart phagolysosome formation. Circumvention of phagolysosome fusion could be either localized to chlamydia-laden vacuoles or generalized to all phagosomes in the host cell. To determine which of these modes is in oper...

journal_title：Infection and immunity

authors： Eissenberg LG,Wyrick PB

更新日期：1981-05-01 00:00:00

abstract：:Lipopolysaccharide (LPS) is one of the most potent trigger substances for monocytes and macrophages causing secretion of tumor necrosis factor alpha (TNF-alpha) and other inflammatory mediators. The nature of the nuclear factors involved in human TNF-alpha gene regulation is still unknown. Nuclear factor kappa B (NF-k...

journal_title：Infection and immunity

authors： Takashiba S,Van Dyke TE,Shapira L,Amar S

更新日期：1995-04-01 00:00:00

abstract：:Active immunization with Porphyromonas gingivalis whole-cell preparations has been shown to prevent P. gingivalis infection and oral bone loss. Employing passive antibody transfer and opsonization, we demonstrate with this study that immunization-elicited P. gingivalis-specific immunoglobulin G facilitates clearance o...

journal_title：Infection and immunity

authors： Gibson FC 3rd,Gonzalez DA,Wong J,Genco CA

更新日期：2004-04-01 00:00:00

abstract：:Phagocytosis and killing by alveolar macrophages from humans, rabbits, rats, and hamsters, were compared in vitro. In the absence of serum opsonins, human alveolar macrophages could phagocytize Staphylococcus aureus Cowan I (protein A positive), but not S. aureus EMS (protein A negative) or Pseudomonas aeruginosa MN. ...

journal_title：Infection and immunity

authors： Nguyen BY,Peterson PK,Verbrugh HA,Quie PG,Hoidal JR

更新日期：1982-05-01 00:00:00

abstract：:Eperythrozoon coccoides is a common blood parasite of rodents and the etiological agent of a chronic infection present in many mouse colonies. After primary infection, mice develop a parasitemia and anemia followed by a chronic, latent infection. During the acute phase of infection, mice manifest a striking suppressio...

journal_title：Infection and immunity

authors： Glasgow LA,Odugbemi T,Dwyer P,Ritterson AL

更新日期：1971-10-01 00:00:00

abstract：:The region of DNA encoding the mannose-fucose-resistant hemagglutinin (MFRHA) of Vibrio cholerae O1 has been localized, and the nucleotide sequence has been determined. The region contains a single open reading frame encoding 230 amino acids, corresponding to a protein of 26.9 kDa. The N terminus of this protein is at...

journal_title：Infection and immunity

authors： Franzon VL,Barker A,Manning PA

更新日期：1993-07-01 00:00:00

abstract：:Human peripheral blood monocytes become apoptotic following phagocytosis of Staphylococcus aureus. In this study, we investigated the mechanisms involved in this phenomenon. Cells exposed to bacteria were examined for the surface expression of Fas and Fas ligand (FasL). The level of soluble form of FasL was also measu...

journal_title：Infection and immunity

authors： Baran J,Weglarczyk K,Mysiak M,Guzik K,Ernst M,Flad HD,Pryjma J

更新日期：2001-03-01 00:00:00

abstract：:Resistance to phagocytosis is a hallmark of virulent Streptococcus pyogenes (group A streptococcus). Surface-bound C5a peptidase reduces recruitment of phagocytes to the site of infection, and hyaluronic acid capsules and/or the M protein limit the uptake of streptococci. In this study the relative impact of M and M-l...

journal_title：Infection and immunity

authors： Ji Y,Schnitzler N,DeMaster E,Cleary P

更新日期：1998-11-01 00:00:00

abstract：:We constructed the expression vector pSK-SCP containing the streptococcal exotoxin B gene (spe b) which expressed protease activity. We showed that the recombinant streptococcal pyogenic exotoxin B/streptococcal cysteine protease (rSPE B/SCP) was secreted into the culture supernatant of the transformant and retained i...

journal_title：Infection and immunity

authors： Watanabe Y,Todome Y,Ohkuni H,Sakurada S,Ishikawa T,Yutsudo T,Fischetti VA,Zabriskie JB

更新日期：2002-07-01 00:00:00

abstract：:Porphyromonas gingivalis is a periodontal pathogen capable of invading primary cultures of normal human gingival epithelial cells (NHGEC). Involvement of P. gingivalis fimbriae in the invasion process was examined. Purified P. gingivalis 33277 fimbriae blocked invasion of this organism into NHGEC in a dose-dependent m...

journal_title：Infection and immunity

authors： Weinberg A,Belton CM,Park Y,Lamont RJ

更新日期：1997-01-01 00:00:00

abstract：:Attachment and ingestion of Mycobacterium avium subsp. paratuberculosis by two epithelial cell lines were enhanced by soluble fibronectin (FN). Peptide blocking of the FN attachment protein (FAP-P) inhibited the internalization of M. avium subsp. paratuberculosis. Disruption of FAP-P expression significantly reduced a...

journal_title：Infection and immunity

authors： Secott TE,Lin TL,Wu CC

更新日期：2002-05-01 00:00:00

abstract：:Herein we characterized various genetic markers and the biological behavior of a natural recombinant strain of Toxoplasma gondii (P-Br). From nine genetic markers analyzed, three (B1, ROP1, and SAG1) and three (cS10-A6, GRA6, and SAG3) markers belong to parasites from the type I and type III lineages, respectively. Th...

journal_title：Infection and immunity

authors： Fux B,Rodrigues CV,Portela RW,Silva NM,Su C,Sibley D,Vitor RW,Gazzinelli RT

更新日期：2003-11-01 00:00:00

abstract：:We characterized outer membrane proteins (OMPs) from selected Campylobacter jejuni, C. coli, and C. fetus strains by two-dimensional gel electrophoresis (2DGE), using isoelectric focusing and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and by immunoblotting with immune rabbit serum. The flage...

journal_title：Infection and immunity

authors： Dunn BE,Blaser MJ,Snyder EL

更新日期：1987-07-01 00:00:00

abstract：:Genetic diversity and relationships among 109 isolates of Neisseria meningitidis obtained from throat cultures of healthy individuals in Norway in 1984 were assessed by analyzing electrophoretically demonstrable allelic variation at 15 enzyme-encoding chromosomal genes. Seventy-eight distinctive electrophoretic types ...

journal_title：Infection and immunity

authors： Caugant DA,Kristiansen BE,Frøholm LO,Bøvre K,Selander RK

更新日期：1988-08-01 00:00:00

abstract：:Borrelia burgdorferi, the Lyme disease pathogen, dramatically alters its protein profile when it is transmitted between ticks and mammals. Several differentially expressed proteins have been shown to be critical for the enzootic cycle of B. burgdorferi. In this study, we demonstrated that expression of the surface lip...

journal_title：Infection and immunity

authors： Xu H,He M,He JJ,Yang XF

更新日期：2010-07-01 00:00:00