Immunological response to the Brucella abortus GroEL homolog.

abstract：:The immune response of humans and mice to temperature-specific, plasmid- or chromosome-encoded proteins of yersinia pestis and Yersinia enterocolitica was investigated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting. Extracts from Y. pestis and Y. enterocolitica strains with and witho...

journal_title：Infection and immunity

authors： Mazza G,Karu AE,Kingsbury DT

更新日期：1985-06-01 00:00:00

abstract：:Mycobacterium tuberculosis has a unique family of PE-PGRS proteins with conserved N-terminal domains (PE) containing site-specific proline-glutamine residues and polymorphic GC-rich repetitive sequences (PGRS). Tuberculosis (TB) patients produce antibodies against some such proteins, but it is not clear whether these ...

journal_title：Infection and immunity

authors： Koh KW,Soh SE,Seah GT

更新日期：2009-08-01 00:00:00

abstract：:Recent epidemiological observations suggest that clinical evolution of Plasmodium falciparum infections might be influenced by the concurrent presence of another Plasmodium species, and such mixed-species infections are now known to occur frequently in residents of most areas of endemicity. We used mice infected with ...

journal_title：Infection and immunity

authors： Voza T,Vigário AM,Belnoue E,Grüner AC,Deschemin JC,Kayibanda M,Delmas F,Janse CJ,Franke-Fayard B,Waters AP,Landau I,Snounou G,Rénia L

更新日期：2005-08-01 00:00:00

abstract：:Mice were protected against a lethal infection with Listeria monocytogenes when treated with low doses of an anti-CD3 monoclonal antibody (MAb). Injection of anti-CD3 MAb induced rapid production of endogenous tumor necrosis factor (TNF) in the spleens and endogenous gamma interferon (IFN-gamma) in the bloodstreams an...

journal_title：Infection and immunity

authors： Nakane A,Okamoto M,Asano M,Kohanawa M,Minagawa T

更新日期：1993-07-01 00:00:00

abstract：:The effect of a deficiency in the C5 component of complement on the pathophyisology of infection with the fungal pathogen Candida albicans was studied by using the A/J inbred mouse strain and the BcA17 congenic mouse strain. Acute infection caused by intravenous injection of C. albicans blastospores is associated with...

journal_title：Infection and immunity

authors： Mullick A,Leon Z,Min-Oo G,Berghout J,Lo R,Daniels E,Gros P

更新日期：2006-08-01 00:00:00

abstract：:Neisseria lactamica, a common human pharyngeal commensal, contributes to acquired immunity to Neisseria meningitidis. To define the surface antigens shared between these two species, we used monoclonal antibodies (MAbs) to study 35 N. lactamica strains isolated in various parts of the world for cross-reactivity with m...

journal_title：Infection and immunity

authors： Kim JJ,Mandrell RE,Griffiss JM

更新日期：1989-02-01 00:00:00

abstract：:Conventional adult mice were pretreated with metronidazole to make their intestinal tracts receptive to colonization by Clostridium botulinum. These mice, in groups of 10, were fed 0 (controls), 10(2), 10(3), 10(4), or 10(5) C. botulinum type B spores and were placed for observation in filter-lid cages whose screen fl...

journal_title：Infection and immunity

authors： Wang Y,Sugiyama H

更新日期：1984-12-01 00:00:00

abstract：:Curli are thin, coiled fibers expressed on the surface of Escherichia coli that bind several matrix and plasma proteins such as fibronectin, laminin, plasminogen, tissue plasminogen activator, and H-kininogen. In this work, we examined the interactions between curli-expressing E. coli and human major histocompatibilit...

journal_title：Infection and immunity

authors： Olsén A,Wick MJ,Mörgelin M,Björck L

更新日期：1998-03-01 00:00:00

abstract：:By using in vitro assays, a group of related, filamentous gram-negative bacteria isolated from subgingival plaque deposits of patients with periodontal disease were found to colonize intact teeth. Tentatively identified as members of the genus Cytophaga, these isolates exhibited a preference for colonizing the cementu...

journal_title：Infection and immunity

authors： Celesk RA,McCabe RM,London J

更新日期：1979-10-01 00:00:00

abstract：:Helicobacter mustelae is a urease-rich bacterium associated with gastritis in ferrets. The ureases of H. mustelae and Helicobacter pylori, a bacterium implicated in human gastritis, share many characteristics. Helicobacter sp. ureases appear to be unique among bacterial enzymes in exhibiting submillimolar Km values an...

journal_title：Infection and immunity

authors： Dunn BE,Sung CC,Taylor NS,Fox JG

更新日期：1991-09-01 00:00:00

abstract：:Corynebacteriophage 782, a phage highly related to the beta family of corynebacteriophages but lacking a tox allele, was isolated from a nontoxinogenic clinical isolate of Corynebacterium diphtheriae. Phage 782 exhibits beta immunity but has a wider host range than beta, forming plaques on strains of C. ulcerans and C...

journal_title：Infection and immunity

authors： Cianciotto N,Groman N

更新日期：1985-07-01 00:00:00

abstract：:Recent preclinical and epidemiologic studies have suggested that certain Mycobacterium tuberculosis genotypes (in particular, Beijing lineage strains) may be resistant to Mycobacterium bovis BCG vaccine-induced antituberculosis protective immunity. To investigate the strain specificity of BCG-induced protective respon...

journal_title：Infection and immunity

authors： Jeon BY,Derrick SC,Lim J,Kolibab K,Dheenadhayalan V,Yang AL,Kreiswirth B,Morris SL

更新日期：2008-11-01 00:00:00

abstract：:The role of CD8 T cells in controlling Mycobacterium tuberculosis infections in mice was confirmed by comparing the levels of growth of the organism in control, major histocompatibility complex class II knockout, and athymic mice and by transferring T-cell populations into athymic mice. By using donor mice which were ...

journal_title：Infection and immunity

authors： Tascon RE,Stavropoulos E,Lukacs KV,Colston MJ

更新日期：1998-02-01 00:00:00

abstract：:Bacterial products from gram-positive bacteria, such as peptidoglycan, teichoic acid, and toxins, activate mononuclear cells to produce tumor necrosis factor alpha (TNF). The present study evaluated the release of soluble cell wall components from Staphylococcus epidermidis capable of inducing TNF after exposure of th...

journal_title：Infection and immunity

authors： Mattsson E,Van Dijk H,Verhoef J,Norrby R,Rollof J

更新日期：1996-10-01 00:00:00

abstract：:Factors which control the levels of catalase within yeast cells of Histoplasma capsulatum were studied. Only a small fraction of the total catalase activity could be detected in whole cells. The bulk of the activity was revealed in cell-free extracts or in cells permeabilized with acetone. The formation of the enzyme ...

journal_title：Infection and immunity

authors： Howard DH

更新日期：1983-03-01 00:00:00

abstract：:Human gingival fibroblasts were exposed in culture to cell extracts of different black-pigmented Bacteroides species, and their growth was monitored by determining thymidine uptake and counting cells. Of the Bacteroides species tested (B. gingivalis, B. asaccharolyticus, and B. intermedius), B. gingivalis gave the ext...

journal_title：Infection and immunity

authors： Larjava H,Uitto VJ,Eerola E,Haapasalo M

更新日期：1987-01-01 00:00:00

abstract：:Cell-mediated immunity to varicella-zoster (V-Z) virus in persons immune to varicella has been demonstrated, using a tissue culture technique. Cell-mediated immunity was reflected by the ability of peripheral leukocytes (lymphocytes and monocytes) from human donors to inactivate V-Z virus. Leukocytes were stimulated b...

journal_title：Infection and immunity

authors： Gershon AA,Steinberg S,Smith M

更新日期：1976-06-01 00:00:00

abstract：:The pathogenesis of Staphylococcus aureus infections is influenced by multiple virulence factors that are expressed under variable conditions, and this has complicated the design of an effective vaccine. Clinical trials that targeted the capsule or clumping factor A (ClfA) failed to protect the recipients against stap...

journal_title：Infection and immunity

authors： Tuchscherr LP,Buzzola FR,Alvarez LP,Lee JC,Sordelli DO

更新日期：2008-12-01 00:00:00

abstract：:Mouse spleen cultures were infected with murine cytomegalovirus, either before or after separating the cells into various classes, and the growth of virus and production of infectious centers were measured in each cell class. The separation techniques, which were used in various combinations, comprised: adherence to p...

journal_title：Infection and immunity

authors： Loh L,Hudson JB

更新日期：1979-12-01 00:00:00

abstract：:After transmission by Anopheles mosquitoes, Plasmodium sporozoites travel to the liver, infect hepatocytes, and rapidly develop as intrahepatocytic liver stages (LS). Rodent models of malaria exhibit large differences in the magnitude of liver infection, both between parasite species and between strains of mice. This ...

journal_title：Infection and immunity

authors： Kaushansky A,Austin LS,Mikolajczak SA,Lo FY,Miller JL,Douglass AN,Arang N,Vaughan AM,Gardner MJ,Kappe SH

更新日期：2015-01-01 00:00:00

abstract：:In a previous report (Y. Ohmori, S. Hanazawa, S. Amano, T. Miyoshi, K. Hirose, and S. Kitano, infect. Immun. 55:947-954, 1987), we showed that human gingival fibroblasts spontaneously produce thymocyte-activating factor (FTAF), which stimulates mitogen-induced thymocyte proliferation. In the present study, we examined...

journal_title：Infection and immunity

authors： Hanazawa S,Hirose K,Ohmori Y,Amano S,Kitano S

更新日期：1988-01-01 00:00:00

abstract：:The structural gene of pneumolysin was randomly mutagenized. A screen, developed to identify mutants with reduced hemolytic activity, identified substitutions within the cysteine-containing region and also at residues toward the N terminus of the toxin. These are the first reported changes within the N-terminal region...

journal_title：Infection and immunity

authors： Hill J,Andrew PW,Mitchell TJ

更新日期：1994-02-01 00:00:00

abstract：:Previous studies have demonstrated that the Moraxella catarrhalis surface antigen UspA1 is an adhesin for Chang human conjunctival cells. The present report demonstrates that lack of UspA1 expression does not affect the adherence of strain O35E to A549 human lung cells or primary cultures of human middle ear epithelia...

journal_title：Infection and immunity

authors： Holm MM,Vanlerberg SL,Sledjeski DD,Lafontaine ER

更新日期：2003-09-01 00:00:00

abstract：:In its canonical role the reverse transcriptase telomerase recovers the telomeric repeats that are lost during DNA replication. Other locations and activities have been recently described for the telomerase protein subunit TERT in mammalian cells. In the present work, using biochemistry, molecular biology, and electro...

journal_title：Infection and immunity

authors： Campelo R,Díaz Lozano I,Figarella K,Osuna A,Ramírez JL

更新日期：2015-01-01 00:00:00

abstract：:It has been proposed that a multivalent malaria vaccine is necessary to mimic the naturally acquired resistance to this disease observed in humans. A major experimental challenge is to identify the optimal components to be used in such a multivalent vaccine. Expression library immunization (ELI) is a method for screen...

journal_title：Infection and immunity

authors： Rainczuk A,Scorza T,Smooker PM,Spithill TW

更新日期：2003-08-01 00:00:00

abstract：:Mannan (MAN) extracted from Candida albicans 20A was investigated for its potential as an antigen in the detection of cell-mediated immunity (CMI) in vivo and in vitro and for its ability to modulate CMI when administered intravenously (i.v.). CBA/J mice were either immunized as adults by the cutaneous inoculation of ...

journal_title：Infection and immunity

authors： Domer JE,Garner RE,Befidi-Mengue RN

更新日期：1989-03-01 00:00:00

abstract：:Bordetella pertussis adenylate cyclase-hemolysin (AC-Hly), encoded by the cyaA gene, belongs to the RTX family of toxins with extensive glycine-rich repeats in the carboxy-terminal portion. AC-Hly possesses both adenylate cyclase toxic and hemolytic activities that depend on a posttranslational modification mediated b...

journal_title：Infection and immunity

authors： Betsou F,Sebo P,Guiso N

更新日期：1993-09-01 00:00:00

abstract：:The ability of various strains of rats to produce interferon in response to polyriboinosinic-polyribocytodilic acid was investigated. ACI and DA (RT-1a), BN (RT-1n), Buffalo (RT-1b), August (RT-1c), and GH (RT-1l) strains produced low levels of interferon in response to intraperitoneal administration of polyriboinosin...

journal_title：Infection and immunity

authors： Davis CT,Blankenhorn EP,Murasko DM

更新日期：1984-02-01 00:00:00

abstract：:Pneumocystis carinii pneumonia (PcP) is a clinically important infection of immunocompromised patients. Although the interaction of Pneumocystis with the alveolar epithelium has been well documented, very little information regarding the epithelial response to Pneumocystis is currently available. In order to study Pne...

journal_title：Infection and immunity

authors： Wang J,Gigliotti F,Maggirwar S,Johnston C,Finkelstein JN,Wright TW

更新日期：2005-05-01 00:00:00

abstract：:Shigella flexneri is a gram-negative bacterium that causes bacillary dysentery in humans that is characterized by an acute inflammatory response of the colon. The fate of phagocytes that are infected in vitro with virulent Shigella has been the subject of some investigation and debate. In this study we found that viru...

journal_title：Infection and immunity

authors： Koterski JF,Nahvi M,Venkatesan MM,Haimovich B

更新日期：2005-01-01 00:00:00