Neisseria lactamica and Neisseria meningitidis share lipooligosaccharide epitopes but lack common capsular and class 1, 2, and 3 protein epitopes.

abstract：:The opacity (Opa) proteins mediate a variety of interactions between the bacterium Neisseria meningitidis and its human host. These interactions are thought to be of central importance in both the asymptomatic colonization of the nasopharynx and the sporadic occurrence of meningococcal disease. The receptor specificit...

journal_title：Infection and immunity

authors： Callaghan MJ,Jolley KA,Maiden MC

更新日期：2006-09-01 00:00:00

abstract：:Collectins play important roles in host defense against infectious microorganisms. We now demonstrate that the serum collectins mannose-binding lectin (MBL) and conglutinin have less ability to bind to, aggregate, and enhance neutrophil uptake of several strains of gram-negative and gram-positive bacteria than pulmona...

journal_title：Infection and immunity

authors： Hartshorn KL,White MR,Crouch EC

更新日期：2002-11-01 00:00:00

abstract：:Intravenous injection of rat anti-mouse gamma interferon (IFN-gamma) monoclonal antibody as well as rabbit anti-mouse tumor necrosis factor (TNF) antibody into mice which had received a sublethal infection with Listeria monocytogenes cells resulted in acceleration of listeriosis. Endogenous IFN-gamma seemed to be prod...

journal_title：Infection and immunity

authors： Nakane A,Minagawa T,Kohanawa M,Chen Y,Sato H,Moriyama M,Tsuruoka N

更新日期：1989-11-01 00:00:00

abstract：:No studies to date clearly define the interactions between Porphyromonas gingivalis and human peripheral blood polymorphonuclear leukocytes (PMN), nor has a protective role for antibody to P. gingivalis been defined. Using a fluorochrome phagocytosis microassay, we investigated PMN phagocytosis and killing of P. gingi...

journal_title：Infection and immunity

authors： Cutler CW,Kalmar JR,Arnold RR

更新日期：1991-06-01 00:00:00

abstract：:Tularemia is caused by the Gram-negative bacterial pathogen Francisella tularensis Infection of macrophages and their subsequent death are believed to play important roles in the progression of disease. Because complement is a particularly effective opsonin for Francisella, we asked whether complement-dependent uptake...

journal_title：Infection and immunity

authors： Brock SR,Parmely MJ

更新日期：2017-09-20 00:00:00

abstract：:Recruitment of neutrophils to lung tissue and airspaces is a hallmark of inflammatory events following inhalation of endotoxins. We studied the role of different lymphocyte subsets in this inflammation, which is assumed to primarily involve the innate immune system. Inhalation of aerosolized Escherichia coli lipopolys...

journal_title：Infection and immunity

authors： Larsson R,Rocksén D,Lilliehöök B,Jonsson A,Bucht A

更新日期：2000-12-01 00:00:00

abstract：:The formation of water-insoluble glucan by extracellular glucosyltransferase from Streptococcus mutans 6715 found to be greatly stimulated by various mono- or divalent cations. An enzyme preparation, obtained by ethanol fractionation, was able to catalyze the formation of water-insoluble glucan from sucrose in the pre...

journal_title：Infection and immunity

authors： Mukasa H,Shimamura A,Tsumori H

更新日期：1979-03-01 00:00:00

abstract：:The Lyme disease spirochete, Borrelia burgdorferi, is introduced into human hosts via tick bites. Among the cell types present in the skin which may initially contact spirochetes are mast cells. Since spirochetes are known to activate a variety of cell types in vitro, we tested whether B. burgdorferi spirochetes could...

journal_title：Infection and immunity

authors： Talkington J,Nickell SP

更新日期：1999-03-01 00:00:00

abstract：:Streptococcus pneumoniae, a Gram-positive bacterial pathogen, causes pneumonia, meningitis, and septicemia. Innate immune responses are critical for the control and pathology of pneumococcal infections. It has been demonstrated that S. pneumoniae induces the production of type I interferons (IFNs) by host cells and th...

journal_title：Infection and immunity

authors： Fang R,Hara H,Sakai S,Hernandez-Cuellar E,Mitsuyama M,Kawamura I,Tsuchiya K

更新日期：2014-06-01 00:00:00

abstract：:Secretion of immunoglobulin A1 (IgA1) proteases is a characteristic of Haemophilus influenzae and several other bacterial pathogens causing infectious diseases, including meningitis. Indirect evidence suggests that the proteases are important virulence factors. In this study, we cloned the iga gene encoding immunoglob...

journal_title：Infection and immunity

authors： Poulsen K,Brandt J,Hjorth JP,Thøgersen HC,Kilian M

更新日期：1989-10-01 00:00:00

abstract：:Sephadex G-200 filtration was used for fractionating dengue type 2 (DEN-2)-infected suckling mouse brain (SMB) supernatant fluids. The high-molecular-weight fraction, which was eluted in the void volume, showed no increase in type specificity when tested against immune ascitic fluid to the four prototype dengue viruse...

journal_title：Infection and immunity

authors： Cornesky RA,Hammon WM,Atchison RW,Sather GE

更新日期：1972-12-01 00:00:00

abstract：:Transposon mutagenesis was used to analyze Mycoplasma pneumoniae cytadherence. Mycoplasmas were electroporated with Tn4001, and transformants were identified by antibiotic selection using gentamicin. The resulting colonies were screened for hemadsorption (HA) as an indicator for cytadherence. Six HA- colonies from ind...

journal_title：Infection and immunity

authors： Hedreyda CT,Krause DC

更新日期：1995-09-01 00:00:00

abstract：:Mesophilic Aeromonas hydrophila strains of serotype O34 typically express smooth lipopolysaccharide (LPS) on their surface. A single mutation in the gene that codes for UDP N-acetylgalactosamine 4-epimerase (gne) confers the O(-) phenotype (LPS without O-antigen molecules) on a strain in serotypes O18 and O34, but not...

journal_title：Infection and immunity

authors： Canals R,Jiménez N,Vilches S,Regué M,Merino S,Tomás JM

更新日期：2006-01-01 00:00:00

abstract：:Virulent strains of Yersinia enterocolitica and their plasmidless, avirulent derivatives were examined for their cell surface properties. Increased surface charge and hydrophobicity of Y. enterocolitica were found to be associated with the possession of a 40- to 48-megadalton plasmid. These surface properties were exp...

journal_title：Infection and immunity

authors： Lachica RV,Zink DL

更新日期：1984-05-01 00:00:00

abstract：:The expression of the Shigella flexneri chromosomal aerobactin genes during growth of the bacterium within tissue culture cells was assayed. During intracellular growth, aerobactin promoter activity was repressed relative to the level observed in bacteria grown extracellularly, even when the bacteria had been starved ...

journal_title：Infection and immunity

authors： Headley V,Hong M,Galko M,Payne SM

更新日期：1997-02-01 00:00:00

abstract：:Pretreatment with multiple doses of polymyxin B and colistimethate was evaluated as to its ability to sequester sufficient antibiotic in tissues to neutralize the effects of endotoxin in three animal models. Animals were challenged with endotoxin 24, 48, or 72 h after the last dose of antibiotic when there was minimal...

journal_title：Infection and immunity

authors： Craig WA,Turner JH,Kunin CM

更新日期：1974-08-01 00:00:00

abstract：:Trypanosoma musculi produces a chronic infection with a consistently elevated parasitemia in nude mice. Thymic reconstitution of nude mice restores immunity to the infection. ...

journal_title：Infection and immunity

authors： Rank RG,Roberts DW,Weidanz WP

更新日期：1977-05-01 00:00:00

abstract：:Brucella abortus is recognized by several Toll-like receptor (TLR)-associated pathways triggering proinflammatory responses that affect both the nature and intensity of the immune response. Previously, we demonstrated that B. abortus-mediated dendritic cell (DC) maturation and control of infection are dependent on the...

journal_title：Infection and immunity

authors： de Almeida LA,Macedo GC,Marinho FA,Gomes MT,Corsetti PP,Silva AM,Cassataro J,Giambartolomei GH,Oliveira SC

更新日期：2013-05-01 00:00:00

abstract：:Rabbits were immunized with the synthetic peptide EENVEHDA or (EENV)2, corresponding to a tandemly repeated sequence in the C-terminal part of the Plasmodium falciparum antigen Pf155/RESA, or with Escherichia coli-derived fusion proteins containing the corresponding repeats. For all sera, the capacity of the total imm...

journal_title：Infection and immunity

authors： Wåhlin B,Berzins K,Perlmann H,Anders RF,Perlmann P

更新日期：1990-09-01 00:00:00

abstract：:A total of five bacteriological samples from the periodontal pockets of two sisters with localized juvenile periodontitis and their mother with advanced periodontitis was studied. Gram-negative anaerobic rods were predominant in the samples. Bacteroides intermedius and Bacteroides loescheii were the most predominant s...

journal_title：Infection and immunity

authors： Okuda K,Naito Y,Ohta K,Fukumoto Y,Kimura Y,Ishikawa I,Kinoshita S,Takazoe I

更新日期：1984-07-01 00:00:00

abstract：:Exposure to bacterial superantigens such as staphylococcal enterotoxin B (SEB) leads to the induction of toxic shock syndrome which results in multiorgan failure, including liver damage. In the present study, we investigated the role of CD44 in SEB-induced liver injury. Injection of SEB into d-galactosamine-sensitized...

journal_title：Infection and immunity

authors： McKallip RJ,Fisher M,Gunthert U,Szakal AK,Nagarkatti PS,Nagarkatti M

更新日期：2005-01-01 00:00:00

abstract：:F1651 and the pyelonephritis-associated pili (Pap) are two members of the type P family of adhesive factors. They play a key role in establishing disease caused by extraintestinal pathogenic Escherichia coli (ExPEC) strains in animals and humans. Both F1651 and Pap are under the control of an epigenetic and reversible...

journal_title：Infection and immunity

authors： Graveline R,Lavoie R,Garneau P,Daigle F,Sénéchal S,Martin C,Harel J

更新日期：2015-05-01 00:00:00

abstract：:The serotype-specific polysaccharide of Streptococcus mutans AHT (serotype a) was shown to be loosely associated with the cell surface of this organism. The antigen was extracted from whole cells by boiling in sodium acetate buffer, pH 4.0, for 10 min. The purified product was found to be a diheteroglycan of galactose...

journal_title：Infection and immunity

authors： Craig RA,Riege DH,Bleiweis AS

更新日期：1979-12-01 00:00:00

abstract：:Chronic granulomatous disease (CGD) is a genetic disorder of NADPH oxidase in which phagocytes are defective in generating reactive oxidants. CGD patients suffer from recurrent infections and exuberant and persistent tissue granuloma formation. We hypothesized that abnormal granulomata in CGD may result from aberrant ...

journal_title：Infection and immunity

authors： Segal BH,Doherty TM,Wynn TA,Cheever AW,Sher A,Holland SM

更新日期：1999-04-01 00:00:00

abstract：:The mechanism by which bacterial heat-stable enterotoxins (ST I STA) cause diarrhea in humans and animals has been linked to the activation of an intestinal membrane-bound guanylate cyclase. Guanylin, a recently discovered rat intestinal peptide, is homologous in structure to ST I and can activate guanylate cyclase pr...

journal_title：Infection and immunity

authors： Carpick BW,Gariépy J

更新日期：1993-11-01 00:00:00

abstract：:The enteric pathogen Shigella is one of the leading causes of moderate-to-severe diarrhea and death in young children in developing countries. Transformed cell lines and animal models have been widely used to study Shigella pathogenesis. In addition to altered physiology, transformed cell lines are composed of a singl...

journal_title：Infection and immunity

authors： Ranganathan S,Doucet M,Grassel CL,Delaine-Elias B,Zachos NC,Barry EM

更新日期：2019-03-25 00:00:00

abstract：:Toxoplasma gondii is a ubiquitous parasite that persists for the life of a healthy mammalian host. A latent, chronic infection can reactivate upon immunosuppression and cause life-threatening diseases, such as encephalitis. A key to the pathogenesis is the parasite's interconversion between the tachyzoite (in acute in...

journal_title：Infection and immunity

authors： Kim SK,Karasov A,Boothroyd JC

更新日期：2007-04-01 00:00:00

abstract：:Reverse transcriptase PCR analyses have demonstrated that open reading frames (ORFs) PM0298, PM0299, and PM0300 of the animal pathogen Pasteurella multocida constitute a single transcriptional unit. By cloning and overexpression studies in Escherichia coli cells, the product of ORF PM0300 was shown to bind hemoglobin ...

journal_title：Infection and immunity

authors： Bosch M,Garrido ME,Llagostera M,Pérez De Rozas AM,Badiola I,Barbé J

更新日期：2002-11-01 00:00:00

abstract：:Herpes simplex virus (HSV) infection of mouse liver after partial hepatectomy was studied. Partial hepatectomy resulted in the rapid onset of cellular DNA synthesis and the appearance of many mitotic figures (peak, 3 days after surgery). Similar changes were not seen in control animals. After partial hepatectomy, the ...

journal_title：Infection and immunity

authors： Fang ZY,Tenser RB,Rapp F

更新日期：1983-10-01 00:00:00

abstract：:The combining sites of type 1 fimbrial lectins of various species of enterobacteria were studied by measuring the inhibitory activity of linear and branched oligosaccharides and several glycosides of D-mannose on the agglutination of yeast cells by the organisms. The results showed that all five strains of Escherichia...

journal_title：Infection and immunity

authors： Firon N,Ofek I,Sharon N

更新日期：1984-03-01 00:00:00