Discordant influence of Blastomyces dermatitidis yeast-phase-specific gene BYS1 on morphogenesis and virulence.

abstract：:In a cross-sectional survey of 187 Gambian children and adults, we have analyzed prevalence, fine specificity, and 19-kilodalton merozoite surface protein 1 (MSP-1(19))-specific erythrocyte invasion inhibitory activity of antibodies to MSP-1(19) but find no significant association between any of these parameters and p...

journal_title：Infection and immunity

authors： Corran PH,O'Donnell RA,Todd J,Uthaipibull C,Holder AA,Crabb BS,Riley EM

更新日期：2004-10-01 00:00:00

abstract：:Pathogenic strains of Yersinia spp. inject a set of Yop effector proteins into eukaryotic cells by using a plasmid-encoded type III secretion system. In this study, we analyzed the inflammatory response of human umbilical vein endothelial cells (HUVECs) after infection with different Yersinia enterocolitica strains. W...

journal_title：Infection and immunity

authors： Denecker G,Tötemeyer S,Mota LJ,Troisfontaines P,Lambermont I,Youta C,Stainier I,Ackermann M,Cornelis GR

更新日期：2002-07-01 00:00:00

abstract：:Spiroplasmas were propagated in the Drosophila melanogaster cell line Dm-1. Spiroplasma citri and unidentified strains (corn shunt organism, 277F [tick isolate], powder puff, BNR-1, honey bee, and OBMG) grew to 10(8) to 10(9) colony-forming units per ml and could be passaged. Cytopathic effect (CPE) varied with the in...

journal_title：Infection and immunity

authors： Steiner T,McGarrity GJ,Phillips DM

更新日期：1982-01-01 00:00:00

abstract：:T cell-independent antibody responses develop rapidly, within 3 to 4 days, and are critical for preventing blood-borne pathogens from evolving into life-threatening infections. The interaction of BAFF, also known as BLyS, with its receptors BAFFR and TACI on B cells is critical for B cell homeostasis and function. Usi...

journal_title：Infection and immunity

authors： Dickinson GS,Sun G,Bram RJ,Alugupalli KR

更新日期：2014-01-01 00:00:00

abstract：:The adherence of 58 nontypeable Haemophilus influenzae isolates obtained from patients with otitis media or chronic obstructive pulmonary disease (COPD) and obtained from the throats of healthy individuals to Chang and NCI-H292 epithelial cells was compared. Otitis media isolates, but not COPD isolates, adhered signif...

journal_title：Infection and immunity

authors： van Schilfgaarde M,van Ulsen P,Eijk P,Brand M,Stam M,Kouame J,van Alphen L,Dankert J

更新日期：2000-08-01 00:00:00

abstract：:The ocular damage in young adult mice produced by purified Pseudomonas aeruginosa exotoxin A was microscopically characterized at 1 and 5 h and at 1, 3, 5, 7, 10, 14, and 21 days after toxin A challenge, using light, transmission, and scanning electron microscopic techniques. Similarly to previously described infectio...

journal_title：Infection and immunity

authors： Hazlett LD,Berk RS,Iglewski BH

更新日期：1981-12-01 00:00:00

abstract：:Nontypeable Haemophilus influenzae (NTHI) is an important etiological agent of otitis media (OM) and of exacerbated chronic obstructive pulmonary diseases (COPD). Inflammation is a hallmark of both diseases. Interleukin-8 (IL-8), one of the important inflammatory mediators, is induced by NTHI and may play a significan...

journal_title：Infection and immunity

authors： Wang B,Cleary PP,Xu H,Li JD

更新日期：2003-10-01 00:00:00

abstract：:Patients that have suffered a major injury may sustain a period of immunocompromise and altered Th1/Th2 cytokine balance that can predispose them to opportunistic infections. Pseudomonas aeruginosa is frequently a causative organism for nosocomial infections in critically ill patients and is associated with high morta...

journal_title：Infection and immunity

authors： Murphey ED,Herndon DN,Sherwood ER

更新日期：2004-12-01 00:00:00

abstract：:Analysis of the specificity of bactericidal antibodies in normal, convalescent, and postvaccination human sera is important in understanding human immunity to meningococcal infections and can aid in the design of an effective group B vaccine. A collection of human sera, including group C and group B convalescent-phase...

journal_title：Infection and immunity

authors： Schmiel DH,Moran EE,Keiser PB,Brandt BL,Zollinger WD

更新日期：2011-10-01 00:00:00

abstract：:Di-, tri-, and tetrasaccharides, synthesized according to the chemical structure of pneumococcal polysaccharide type 3 (PS3), were coupled to the cross-reactive material (CRM(197)) of modified diphtheria toxin in different molar carbohydrate/protein ratios using the squarate coupling method. To study protective immuni...

journal_title：Infection and immunity

authors： Benaissa-Trouw B,Lefeber DJ,Kamerling JP,Vliegenthart JF,Kraaijeveld K,Snippe H

更新日期：2001-07-01 00:00:00

abstract：:It was shown in this work that the infectivity of metacyclic forms of Trypanosoma cruzi was affected upon interaction with the monoclonal antibody (10D8), which reacts with a carbohydrate epitope of the 35- and 50-kilodalton (kDa) surface glycoconjugates. The invasion of Vero cells by metacyclic forms of strains Tulah...

journal_title：Infection and immunity

authors： Yoshida N,Mortara RA,Araguth MF,Gonzalez JC,Russo M

更新日期：1989-06-01 00:00:00

abstract：:The essential role of T cells in the resolution of primary murine Chlamydia trachomatis genital tract infection is inarguable; however, much less is known about the mechanisms that confer resistance to reinfection. We previously established that CD4+ T cells and B cells contribute importantly to resistance to reinfect...

journal_title：Infection and immunity

authors： Morrison SG,Morrison RP

更新日期：2001-04-01 00:00:00

abstract：:Both dextransucrase and mutansynthetase activities have been purified from the culture fluids of Streptococcus mutans GS-5 (serotype c). Although homogeneous dextransucrase preparations normally synthesize little insoluble glucan, essentially all of the glucan synthesized by this enzyme in the presence of 1.5 M (NH4)2...

journal_title：Infection and immunity

authors： Kuramitsu HK,Wondrack L

更新日期：1983-11-01 00:00:00

abstract：:Acute pyelonephritis, a complication of Escherichia coli bacteriuria, must represent a bacterial invasion through the kidney epithelium. To study this process, we overlaid bacterial suspensions onto monolayers of cultured human kidney proximal tubular epithelial cells and measured cytotoxicity by release of lactate de...

journal_title：Infection and immunity

authors： Mobley HL,Green DM,Trifillis AL,Johnson DE,Chippendale GR,Lockatell CV,Jones BD,Warren JW

更新日期：1990-05-01 00:00:00

abstract：:Cytoadherence-linked asexual gene 9 (Clag9), a conserved Plasmodium protein expressed during the asexual blood stages, is involved in the cytoadherence of infected red blood cells (RBCs) to the endothelial lining of blood vessels. Here, we show that Plasmodium falciparum Clag9 (PfClag9) is a component of the PfClag9-R...

journal_title：Infection and immunity

authors： Chourasia BK,Deshmukh A,Kaur I,Paul G,Panda A,Rathore S,Singh SK,Theisen M,Mohmmed A,Malhotra P

更新日期：2020-01-22 00:00:00

abstract：:The bactericidal activity of guinea pig and human polymorphonuclear leukocytes (PMNs) against a smooth-intermediate strain (45/0) and a rough strain (45/20) of Brucella abortus has been examined. After incubation for 120 min, guinea pig PMNs incubated with either the smooth strain 45/0 or the rough strain 45/20 exhibi...

journal_title：Infection and immunity

authors： Kreutzer DL,Dreyfus LA,Robertson DC

更新日期：1979-03-01 00:00:00

abstract：:Bordetella pertussis fimbriae are composed of a major subunit, Fim2 or Fim3, and the minor subunit FimD. Using immunoelectron microscopy, we provide evidence that FimD is located at the fimbrial tip. The role of FimD in colonization of the mouse respiratory tract was studied by using two fimbrial mutants: a mutant com...

journal_title：Infection and immunity

authors： Geuijen CA,Willems RJ,Bongaerts M,Top J,Gielen H,Mooi FR

更新日期：1997-10-01 00:00:00

abstract：:The population structure of the Bacillus cereus group (52 strains of B. anthracis, B. cereus, and B. thuringiensis) was investigated by sequencing seven gene fragments (rpoB, gyrB, pycA, mdh, mbl, mutS, and plcR). Most of the strains were classifiable into two large subgroups in six housekeeping gene trees but not in ...

journal_title：Infection and immunity

authors： Ko KS,Kim JW,Kim JM,Kim W,Chung SI,Kim IJ,Kook YH

更新日期：2004-09-01 00:00:00

abstract：:To assess the humoral immunological responses at the subclass level in shigellosis, specific antibody responses against Shigella dysenteriae 1 lipopolysaccharide (LPS), S. flexneri Y LPS, invasion plasmid-coded protein antigens (Ipa), and Shiga toxin were analyzed. Antibody responses of 41 patients with S. dysenteriae...

journal_title：Infection and immunity

authors： Islam D,Wretlind B,Ryd M,Lindberg AA,Christensson B

更新日期：1995-05-01 00:00:00

abstract：:The growth of Eimeria vermiformis within cultured murine fibroblastlike (L-929) or rat epithelial-like (RATEC) cells was inhibited by treatment of the cells with the appropriate recombinant gamma interferon. The effect was apparent as a reduction in both the initial numbers of intracellular sporozoites and, to a much ...

journal_title：Infection and immunity

authors： Rose ME,Smith AL,Wakelin D

更新日期：1991-02-01 00:00:00

abstract：:In vitro studies have shown that enterotoxigenic Escherichia coli (ETEC) strains are capable of invading cultured epithelial cells derived from the human ileum and colon. Two separate invasion loci (tia and tib) have previously been isolated from the classical ETEC strain H10407. The tia locus has been shown to direct...

journal_title：Infection and immunity

authors： Mammarappallil JG,Elsinghorst EA

更新日期：2000-12-01 00:00:00

abstract：:The relative roles of serum factors required for opsonization of type XIV Streptococcus pneumoniae were investigated by means of luminol-enhanced chemiluminescence (CL), bactericidal, and immunofluorescence assays employing adult sera containing high (>1,000 ng of antibody nitrogen per ml) or low (<200 ng of antibody ...

journal_title：Infection and immunity

authors： Gardner SE,Anderson DC,Webb BJ,Stitzel AE,Edwards MS,Spitzer RE,Baker CJ

更新日期：1982-03-01 00:00:00

abstract：:Neisseria gonorrhoeae releases peptidoglycan fragments during growth, and these molecules induce an inflammatory response in the human host. The proinflammatory molecules include peptidoglycan monomers, peptidoglycan dimers, and free peptides. These molecules can be released by the actions of lytic transglycosylases o...

journal_title：Infection and immunity

authors： Schaub RE,Perez-Medina KM,Hackett KT,Garcia DL,Dillard JP

更新日期：2019-01-24 00:00:00

abstract：:Borrelia burgdorferi elicits a potent cytokine response through activation of multiple signaling receptors on innate immune cells. Spirochetal lipoproteins initiate expression of NF-κB-dependent cytokines primarily via TLR2, whereas type I interferon (IFN) production is induced through the endosomal receptors TLR7 and...

journal_title：Infection and immunity

authors： Love AC,Schwartz I,Petzke MM

更新日期：2014-06-01 00:00:00

abstract：:CS31A is a K88-related capsule-like surface protein that mediates Escherichia coli and Klebsiella pneumoniae adhesion to the human Caco-2 and Intestine-407 cell lines. In this study, we demonstrate that ClpG, the major subunit of CS31A, contains the adhesive domain of the polymerized structure. We mapped this domain w...

journal_title：Infection and immunity

authors： Di Martino P,Girardeau JP,Der Vartanian M,Joly B,Darfeuille-Michaud A

更新日期：1997-02-01 00:00:00

abstract：:Staphylococcal alpha-toxin was purified from Staphylococcus aureus growth medium using adsorption chromatography on controlled pore glass beads. Elution of alpha-toxin from the unmodified glass surface of the beads with various anions generally followed the chaotropic series. Alpha-toxin, purified by glass bead chroma...

journal_title：Infection and immunity

authors： Cassidy P,Harshman S

更新日期：1976-03-01 00:00:00

abstract：:In its canonical role the reverse transcriptase telomerase recovers the telomeric repeats that are lost during DNA replication. Other locations and activities have been recently described for the telomerase protein subunit TERT in mammalian cells. In the present work, using biochemistry, molecular biology, and electro...

journal_title：Infection and immunity

authors： Campelo R,Díaz Lozano I,Figarella K,Osuna A,Ramírez JL

更新日期：2015-01-01 00:00:00

abstract：:Black melanin-like pigments are produced by several neurotropic fungi, including Cryptococcus neoformans. Pigment production is associated with virulence. In media containing phenolic substrates such as L-dopa, C. neoformans cells become black as a result of pigment accumulation. Pigmented and nonpigmented C. neoforma...

journal_title：Infection and immunity

authors： Wang Y,Aisen P,Casadevall A

更新日期：1995-08-01 00:00:00

abstract：:Leishmania-infected macrophages are potential antigen-presenting cells for CD4+ T lymphocytes, which recognize parasite antigens bound to major histocompatibility complex class II molecules (Ia). However, the intracellular sites where Ia and antigens may interact are far from clear, since parasites grow within the mod...

journal_title：Infection and immunity

authors： Antoine JC,Jouanne C,Lang T,Prina E,de Chastellier C,Frehel C

更新日期：1991-03-01 00:00:00

abstract：:Persistent infection with Borrelia burgdorferi in the presence of a vigorous host immune response has been demonstrated in humans and in animal models of Lyme disease. Long-term persistence of B. burgdorferi was documented recently in our studies of BALB/c and C3H mice infected with cloned and uncloned strains of B. b...

journal_title：Infection and immunity

authors： Persing DH,Mathiesen D,Podzorski D,Barthold SW

更新日期：1994-08-01 00:00:00