Factors affecting colonization and dissemination of Candida albicans from the gastrointestinal tract of mice.

abstract：:Piliated Burkholderia (formerly Pseudomonas) cepacia from sputa of cys tic fibrosis patients in Toronto, Canada, were shown earlier to bind to purified mucins and to a protein receptor on epithelial cells via a 22-kDa adhesin located on unique cable pili. However, a second receptor, thought to be lipid in nature, was ...

journal_title：Infection and immunity

authors： Sylvester FA,Sajjan US,Forstner JF

更新日期：1996-04-01 00:00:00

abstract：:Macrophages can undergo apoptosis after infection with Mycobacterium tuberculosis. This macrophage response deprives the bacillus of its niche cell and supports the host response through better antigen presentation. The intracellular pathways of apoptosis that elaborate this macrophage response are not well understood...

journal_title：Infection and immunity

authors： O'Sullivan MP,O'Leary S,Kelly DM,Keane J

更新日期：2007-04-01 00:00:00

abstract：:The kinetics of cytotoxic T lymphocyte antigen 4 (CTLA-4) expression on T cells responding to Cryptococcus neoformans and its role in regulating the T-cell response were examined. Using peripheral blood mononuclear cells stimulated with encapsulated or acapsular C. neoformans we showed that (i) the encapsulated strain...

journal_title：Infection and immunity

authors： Pietrella D,Perito S,Bistoni F,Vecchiarelli A

更新日期：2001-03-01 00:00:00

abstract：:In order to construct an effector strain for the replacement therapy of dental caries, we wished to combine the properties of low-level acid production and high-level colonization potential in a strain of Streptococcus mutans. To this end, we made a deletion in the lactate dehydrogenase (LDH) gene cloned from the bact...

journal_title：Infection and immunity

authors： Hillman JD,Chen A,Duncan M,Lee SW

更新日期：1994-01-01 00:00:00

abstract：:Heart and muscle tissues appear to be specific target organs for the in vivo inhibition of protein synthesis by diphtheria toxin. ...

journal_title：Infection and immunity

authors： Bowman CG,Imhoff JG,Bonventre PF

更新日期：1970-11-01 00:00:00

abstract：:Brucellosis is a costly disease of water buffaloes (Bubalus bubalis). Latent infections and prolonged incubation of the pathogen limit the efficacy of programs based on the eradication of infected animals. We exploited genetic selection for disease resistance as an approach to the control of water buffalo brucellosis....

journal_title：Infection and immunity

authors： Borriello G,Capparelli R,Bianco M,Fenizia D,Alfano F,Capuano F,Ercolini D,Parisi A,Roperto S,Iannelli D

更新日期：2006-04-01 00:00:00

abstract：:γ9δ2 T cells provide a natural bridge between innate and adaptive immunity, rapidly and potently respond to pathogen infection in mucosal tissues, and are prominently induced by both tuberculosis (TB) infection and bacillus Calmette Guérin (BCG) vaccination. Mycobacterium-expanded γ9δ2 T cells represent only a subset ...

journal_title：Infection and immunity

authors： Xia M,Hesser DC,De P,Sakala IG,Spencer CT,Kirkwood JS,Abate G,Chatterjee D,Dobos KM,Hoft DF

更新日期：2016-08-19 00:00:00

abstract：:Monoclonal antibody WM-25 inhibited the in vitro growth of 13 F38 isolates from goats with contagious caprine pleuropneumonia but not 7 heterologous mycoplasma isolates representing four different species. In contrast to results with polyclonal antisera, growth inhibition by monoclonal antibody WM-25 was specific for ...

journal_title：Infection and immunity

authors： Rurangirwa FR,McGuire TC,Musoke AJ,Kibor A

更新日期：1987-12-01 00:00:00

abstract：:The adherence and aggregation properties of 46 human oral Streptococcus salivarius isolates were examined. A total of 41% of the isolates aggregated with whole human saliva, 50% aggregated with human erythrocytes, and 85% adhered to human buccal epithelial cells. Strains that aggregated with saliva and erythrocytes us...

journal_title：Infection and immunity

authors： Weerkamp AH,McBride BC

更新日期：1980-08-01 00:00:00

abstract：:Anopheles gambiae is the major African vector of Plasmodium falciparum, the most deadly species of human malaria parasite and the most prevalent in Africa. Several strategies are being developed to limit the global impact of malaria via reducing transmission rates, among which are transmission-blocking vaccines (TBVs)...

journal_title：Infection and immunity

authors： Lavazec C,Boudin C,Lacroix R,Bonnet S,Diop A,Thiberge S,Boisson B,Tahar R,Bourgouin C

更新日期：2007-04-01 00:00:00

abstract：:An immunogenic aminopeptidase was purified from Brucella melitensis strain VTRM1. The purification procedure consisted of ammonium sulfate fractionation and three chromatographic steps. This procedure resulted in a yield of 29% and a 144-fold increase in specific activity. The aminopeptidase appeared to be a monomeric...

journal_title：Infection and immunity

authors： Contreras-Rodriguez A,Ramirez-Zavala B,Contreras A,Schurig GG,Sriranganathan N,Lopez-Merino A

更新日期：2003-09-01 00:00:00

abstract：:When tested for their activity in suppressing the acquisition of immunity during acute Besnoitia infection of hamsters, antilymphocyte serum (ALS), aminopterin, cyclophosphamide, cortisol, and whole-body irradiation were the most active agents and effectively blocked the development of immunity during 4 to 12 days of ...

journal_title：Infection and immunity

authors： Wilson HR,Frenkel JK

更新日期：1971-06-01 00:00:00

abstract：:To evaluate the enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides, the rate of isolation of these organisms was compared among individuals with and without diarrhea in Thailand. In two groups of American travelers, A. hydrophila, but not P. shigelloides, was associated with episodes of travelers...

journal_title：Infection and immunity

authors： Pitarangsi C,Echeverria P,Whitmire R,Tirapat C,Formal S,Dammin GJ,Tingtalapong M

更新日期：1982-02-01 00:00:00

abstract：:The objective of this research was to determine whether gram-negative bacteria frequently isolated from periodontally diseased sites contained polyclonal B-cell activators. Polyclonal B-cell activation, which results in nonspecific activation of multiple B-cell clones was analyzed by a hemolysis-in-gel assay designed ...

journal_title：Infection and immunity

authors： Bick PH,Carpenter AB,Holdeman LV,Miller GA,Ranney RR,Palcanis KG,Tew JG

更新日期：1981-10-01 00:00:00

abstract：:Inbred mouse strains differ in their susceptibility to infection with the facultative intracellular bacterium Listeria monocytogenes, largely due to delayed or deficient innate immune responses. Previous antibody depletion studies suggested that neutrophils (polymorphonuclear leukocytes [PMN]) were particularly import...

journal_title：Infection and immunity

authors： Pitts MG,Combs TA,D'Orazio SEF

更新日期：2018-03-22 00:00:00

abstract：:It is proposed that binding of oral streptococci to saliva-coated hydroxylapatite (SHA) surfaces is a multifactorial process involving both specific and nonspecific receptors. In this context, specific binding is described as a high-affinity, saturable interaction between the cell and binding surface. Conversely, nons...

journal_title：Infection and immunity

authors： Staat RH,Peyton JC

更新日期：1984-06-01 00:00:00

abstract：:The presence of hepatitis B surface antigen (HBsAg) and antibody (anti-HBs), hepatitis B e antigen (HBeAg) and antibody (anti-HBe), the nature of T-cell function, and specific cell-mediated immunity to HBsAg were determined and evaluated serially in groups of subjects with chronic HBsAg carrier states and in seronegat...

journal_title：Infection and immunity

authors： Beutner KR,Tiku ML,Ogra PL

更新日期：1978-08-01 00:00:00

abstract：:Many of the virulence factors associated with fulminant group A streptococci (GAS) infection are expressed under in vitro exponential growth conditions. However, the survival of GAS in tissue and intracellularly, as well as colonization of asymptomatic carriers, has been reported for GAS. The bacteria associated with ...

journal_title：Infection and immunity

authors： Leonard BA,Woischnik M,Podbielski A

更新日期：1998-08-01 00:00:00

abstract：:EspG is a conserved protein encoded by the locus of enterocyte effacement (LEE) of attaching and effacing (A/E) pathogens, including enteropathogenic and enterohemorrhagic Escherichia coli and Citrobacter rodentium. EspG is delivered into infected host cells by a type III secretion system. The role of EspG in virulenc...

journal_title：Infection and immunity

authors： Hardwidge PR,Deng W,Vallance BA,Rodriguez-Escudero I,Cid VJ,Molina M,Finlay BB

更新日期：2005-05-01 00:00:00

abstract：:The multiple antigen peptide (MAP) approach is an effective method to chemically synthesize and deliver multiple T-cell and B-cell epitopes as the constituents of a single immunogen. Here we report on the design, chemical synthesis, and immunogenicity of three Plasmodium falciparum MAP vaccines that incorporated antig...

journal_title：Infection and immunity

authors： Mahajan B,Berzofsky JA,Boykins RA,Majam V,Zheng H,Chattopadhyay R,de la Vega P,Moch JK,Haynes JD,Belyakov IM,Nakhasi HL,Kumar S

更新日期：2010-11-01 00:00:00

abstract：:During bacterial infection of the bovine mammary gland, large numbers of leukocytes migrate into the udder, resulting in the establishment of a host response against the pathogen. Currently, the specific leukocyte populations mediating this immune response are not well defined. In the studies described here, we analyz...

journal_title：Infection and immunity

authors： Soltys J,Quinn MT

更新日期：1999-12-01 00:00:00

abstract：:The in vivo role of endogenous interleukin 12 (IL-12) in modulating intrapulmonary growth of Legionella pneumophila was assessed by using a murine model of replicative L. pneumophila lung infection. Intratracheal inoculation of A/J mice with virulent bacteria (10(6) L. pneumophila cells per mouse) resulted in inductio...

journal_title：Infection and immunity

authors： Brieland JK,Remick DG,LeGendre ML,Engleberg NC,Fantone JC

更新日期：1998-01-01 00:00:00

abstract：:Brazilian purpuric fever (BPF)-associated Haemophilus influenzae biogroup aegyptius strain F3031 contains two identical copies of a five gene cluster (hifA to hifE) encoding pili similar to well-characterized Hif fimbriae of H. influenzae type b. HifE, the putative pilus tip adhesin of F3031, shares only 40% amino aci...

journal_title：Infection and immunity

authors： Read TD,Satola SW,Opdyke JA,Farley MM

更新日期：1998-04-01 00:00:00

abstract：:Pseudomallei group Burkholderia species are facultative intracellular parasites that spread efficiently from cell to cell by a mechanism involving the fusion of adjacent cell membranes. Intercellular fusion requires the function of the cluster 5 type VI secretion system (T6SS-5) and its associated valine-glycine repea...

journal_title：Infection and immunity

authors： Toesca IJ,French CT,Miller JF

更新日期：2014-04-01 00:00:00

abstract：:We examined the immunobiological responses to Histoplasma capsulatum in lungs of gamma interferon (IFN-gamma) knockout mice (GKO mice). Naive GKO mice succumbed by day 9 to intranasal challenge with 2.5 x 10(6) yeasts, whereas all wild-type (WT) mice survived for 45 days. Compared to lungs of WT mice, the lungs of acu...

journal_title：Infection and immunity

authors： Allendoerfer R,Deepe GS Jr

更新日期：1997-07-01 00:00:00

abstract：:Virulent Streptococcus suis serotype 2 strains are invasive extracellular bacteria causing septicemia and meningitis in piglets and humans. One objective of this study was to elucidate the function of complement in innate immune defense against S. suis. Experimental infection of wild-type (WT) and C3(-/-) mice demonst...

journal_title：Infection and immunity

authors： Seitz M,Beineke A,Singpiel A,Willenborg J,Dutow P,Goethe R,Valentin-Weigand P,Klos A,Baums CG

更新日期：2014-06-01 00:00:00

abstract：:An enzyme from Treponema denticola that hydrolyzes a synthetic trypsin substrate, N-alpha-benzoyl-L-arginine-p-nitroanilide (BAPNA), was purified to near homogeneity, as judged by gel electrophoresis. The molecular weight of the enzyme was estimated to be ca. 69,000 by sodium dodecyl sulfate-polyacrylamide gel electro...

journal_title：Infection and immunity

authors： Ohta K,Makinen KK,Loesche WJ

更新日期：1986-07-01 00:00:00

abstract：:Trichomonas vaginalis is a sexually transmitted protozoan parasite that undergoes phenotypic variation for numerous surface proteins. A monoclonal antibody (MAb) was used to isolate an approximately 400-bp cDNA encoding a fragment of an important phenotypically varying immunogen of T. vaginalis (Mr = 270 kDa; P270). T...

journal_title：Infection and immunity

authors： Dailey DC,Alderete JF

更新日期：1991-06-01 00:00:00

abstract：:Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in humans and has potential for use as a biological weapon. The genetic basis of the F. tularensis virulence is poorly understood. This study screened a total of 3,936 transposon mutants of the live vaccine strain for infection ...

journal_title：Infection and immunity

authors： Su J,Yang J,Zhao D,Kawula TH,Banas JA,Zhang JR

更新日期：2007-06-01 00:00:00

abstract：:During acute infection with bacteria, viruses or parasites, a fraction of macrophages engulf large numbers of red and white blood cells, a process called hemophagocytosis. Hemophagocytes persist into the chronic stage of infection and have an anti-inflammatory phenotype. Salmonella enterica serovar Typhimurium infecti...

journal_title：Infection and immunity

authors： McDonald EM,Pilonieta MC,Nick HJ,Detweiler CS

更新日期：2015-10-12 00:00:00