Genetic resistance to Brucella abortus in the water buffalo (Bubalus bubalis).

abstract：:In an Escherichia coli strain of human origin, ampicillin resistance and heat-stable enterotoxin activity were shown by EcoRI restriction endonuclease and genetic analysis to be in an 80-megadalton plasmid. ...

journal_title：Infection and immunity

authors： Stieglitz H,Fonseca R,Olarte J,Kupersztoch-Portnoy YM

更新日期：1980-11-01 00:00:00

abstract：:Cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is characterized by a strong Th1 response that leads to skin lesion development. In areas where L. braziliensis transmission is endemic, up to 15% of healthy subjects have tested positive for delayed-type hypersensitivity to soluble leishmania antigen (SLA...

journal_title：Infection and immunity

authors： Cardoso TM,Machado Á,Costa DL,Carvalho LP,Queiroz A,Machado P,Scott P,Carvalho EM,Bacellar O

更新日期：2015-03-01 00:00:00

abstract：:Tularemia is caused by the Gram-negative bacterial pathogen Francisella tularensis Infection of macrophages and their subsequent death are believed to play important roles in the progression of disease. Because complement is a particularly effective opsonin for Francisella, we asked whether complement-dependent uptake...

journal_title：Infection and immunity

authors： Brock SR,Parmely MJ

更新日期：2017-09-20 00:00:00

abstract：:Serologic parameters of kala-azar were evaluated by Western blot analysis. Sera from kala-azar patients with confirmed diagnoses were screened for immunoglobulin G (IgG) and IgG subclass-specific reactivity against Leishmania donovani membrane antigen (LAg). Heterogeneous LAg-specific IgG reactivity with numerous prot...

journal_title：Infection and immunity

authors： Ravindran R,Anam K,Bairagi BC,Saha B,Pramanik N,Guha SK,Goswami RP,Banerjee D,Ali N

更新日期：2004-02-01 00:00:00

abstract：:Swine were infected orally with pure cultures of Treponema hyodysenteriae, and the humoral antibody response was measured by a passive hemolysis test (passive hemagglutination test with the use of complement). Antibody to T. hyodysenteriae was detected as early as 1 week and later on at 4 months after exposure. Howeve...

journal_title：Infection and immunity

authors： Jenkins EM,Sinha PP,Vance RT,Reese GL

更新日期：1976-10-01 00:00:00

abstract：:Pneumolysin is a 471-amino-acid toxin produced by Streptococcus pneumoniae which has both cytolytic and complement activation properties. We have constructed a derivative of the type 2 S. pneumoniae strain D39 in which the portion of the pneumolysin gene encoding amino acids 55 to 437 has been deleted in-frame. The vi...

journal_title：Infection and immunity

authors： Berry AM,Ogunniyi AD,Miller DC,Paton JC

更新日期：1999-02-01 00:00:00

abstract：:Group B streptococci (GBS) are the major cause of neonatal pneumonia, sepsis, and meningitis. Steps considered to be important in the pathogenesis of this infection include colonization of the rectum and vagina of the mother, aspiration of GBS into the fetal lung during or just prior to delivery, and invasion of GBS i...

journal_title：Infection and immunity

authors： Tamura GS,Kuypers JM,Smith S,Raff H,Rubens CE

更新日期：1994-06-01 00:00:00

abstract：:Polyamines such as putrescine, spermidine, and cadaverine are small, polycationic molecules that are required for optimal growth in all cells. The intracellular concentrations of these molecules are maintained by de novo synthesis and transport pathways. The human pathogen Streptococcus pneumoniae possesses a putative...

journal_title：Infection and immunity

authors： Ware D,Jiang Y,Lin W,Swiatlo E

更新日期：2006-01-01 00:00:00

abstract：:Anti-rabbit alveolar macrophage goat serum (AMS), adsorbed of hemolysins and hemagglutinins, exhibited complement-dependent cytotoxicity for the following rabbit target cells: alveolar macrophages, thymocytes, and kidney (RK-13) cells. The intravenous injection of AMS, sufficient to reduce markedly the dermal tubercul...

journal_title：Infection and immunity

authors： Moore VL,Myrvik QN

更新日期：1970-12-01 00:00:00

abstract：:During the systemic phase of murine infection with Salmonella enterica serovar Typhimurium, bacterial virulence is correlated with the ability to grow and survive within host macrophages. Salmonella pathogenicity island 2 (SPI-2), encoding a type three secretion system, has emerged as an important contributor to Salmo...

journal_title：Infection and immunity

authors： Linehan SA,Rytkönen A,Yu XJ,Liu M,Holden DW

更新日期：2005-07-01 00:00:00

abstract：:Menstrually associated toxic shock syndrome (TSS) is attributed primarily to the effects of staphylococcal exotoxin toxic shock syndrome toxin 1 (TSST-1). A region of the 194-amino-acid toxin spanning residues 115 through 144 constitutes a biologically active site. Several point mutations in the TSST-1 gene in that re...

journal_title：Infection and immunity

authors： Bonventre PF,Heeg H,Cullen C,Lian CJ

更新日期：1993-03-01 00:00:00

abstract：:Nontypeable Haemophilus influenzae (NTHi) causes repeated respiratory infections in patients with chronic lung diseases. These infections are characterized by a brisk inflammatory response which results in the accumulation of polymorphonucleated cells in the lungs and is dependent on the expression and secretion of pr...

journal_title：Infection and immunity

authors： Clemans DL,Bauer RJ,Hanson JA,Hobbs MV,St Geme JW 3rd,Marrs CF,Gilsdorf JR

更新日期：2000-08-01 00:00:00

abstract：:The blood-stage development of malaria parasites is initiated by the invasion of merozoites into susceptible erythrocytes. Specific receptor-ligand interactions must occur for the merozoites to first attach to and then invade erythrocytes. Because the invasion process is essential for the parasite's survival and the m...

journal_title：Infection and immunity

authors： Tsuboi T,Kappe SH,al-Yaman F,Prickett MD,Alpers M,Adams JH

更新日期：1994-12-01 00:00:00

abstract：:Studies were carried out to determine whether the in vitro capacity of adherent peritoneal cells to replicate herpes simplex virus type 1 (HSV-1) might correlate with the in vivo susceptibility of mice genetically resistant, moderately susceptible, or very susceptible to HSV-1 infection. Unstimulated and proteose pept...

journal_title：Infection and immunity

authors： Lopez C,Dudas G

更新日期：1979-02-01 00:00:00

abstract：:Nitration of protein A with tetranitromethane incompletely blocks its Fc-binding ability for immunoglobulin G when measured by more sensitive methods of immunoprecipitation and when tested in the enzyme-linked immunosorbent assay. In addition, binding of protein A and blockage by nitration is heterogeneous and depends...

journal_title：Infection and immunity

authors： Sloan GJ,Butler JE

更新日期：1978-08-01 00:00:00

abstract：:Although protective immunity in C57BL/6 mice induced by a single dose of the radiation-attenuated schistosome vaccine is believed to be mediated by Th1-type immune responses, we here report that in BALB/c mice protection can also depend upon signaling via the interleukin-4 (IL-4) receptor which conventionally governs ...

journal_title：Infection and immunity

authors： Mountford AP,Hogg KG,Coulson PS,Brombacher F

更新日期：2001-01-01 00:00:00

abstract：:Bordetella pertussis, the etiological agent of whooping cough, has the ability to modulate its phenotype in response to environmental conditions by using the BvgAS sensory transduction system which is encoded by the vir locus (now known as bvg). The BvgAS system is part of a large family of two-component sensory trans...

journal_title：Infection and immunity

authors： Stenson TH,Peppler MS

更新日期：1995-10-01 00:00:00

abstract：:The in vivo behavior of revertants of Staphylococcus aureus L-phase variants were studied in mice. The Giorgio strain of S. aureus was induced into L-phase variants by methicillin. After 13 serial passages in methicillin agar and six passages in antibiotic-free agar, reversion occurred. Six revertants, all phage untyp...

journal_title：Infection and immunity

authors： Watanakunakorn C,Glotzbecker C

更新日期：1975-06-01 00:00:00

abstract：:Human sera were examined by an enzyme-linked immunosorbent assay for immunoglobulin G (IgG) and IgM antibodies to purified type III polysaccharide of group B streptococci. The antigen-binding capacity of a reference human serum was determined by a radioimmunoassay, and the total antibody content was determined by quan...

journal_title：Infection and immunity

authors： Anthony BF,Concepcion NF,Wass CA,Heiner DC

更新日期：1984-10-01 00:00:00

abstract：:The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The asymmetric character and unique biochemistry of LPS molecules contribute to the OM's ability to function as a molecular permeability barrier tha...

journal_title：Infection and immunity

authors： Giordano NP,Cian MB,Dalebroux ZD

更新日期：2020-06-22 00:00:00

abstract：:We have cloned and sequenced the d15 gene from two strains of Haemophilus influenzae type b (Hib) and two strains of nontypeable H. influenzae (NTHI). The nucleotide and deduced protein sequences of d15 are highly conserved, with only a small variable region identified near the carboxyl terminus of the protein. Analys...

journal_title：Infection and immunity

authors： Loosmore SM,Yang YP,Coleman DC,Shortreed JM,England DM,Klein MH

更新日期：1997-09-01 00:00:00

abstract：:Complement-fixing antibodies were first detected in mice 7 days after intravenous injection with Mycoplasma arthritidis. Peak titers were observed at 21 days, and high levels of antibody persisted through 293 days. The metabolism-inhibiting antibody response was minimal. On fractionation of mouse sera, only 7S antibod...

journal_title：Infection and immunity

authors： Coke BC,Ward JR,Golightly-Rowland C,Trapp GA

更新日期：1971-10-01 00:00:00

abstract：:Two distinct and complementary pathways, one mediated by perforin and the other dependent upon CD95 (Fas), effect cell-mediated cytotoxicity. We examined the relative roles of these pathways in host defenses against the intracellular bacterial pathogen Listeria monocytogenes by using murine listeriosis as a model syst...

journal_title：Infection and immunity

authors： Jensen ER,Glass AA,Clark WR,Wing EJ,Miller JF,Gregory SH

更新日期：1998-09-01 00:00:00

abstract：:Toxic shock syndrome (TSS) toxin 1 (TSST1) is produced by strains of Staphylococcus aureus associated with TSS. Purified TSST1 induces in rabbits a shock-like illness with many features similar to TSS in humans. These symptoms were also induced by TSST1-producing bacteria in diffusion chambers implanted in the rabbit ...

journal_title：Infection and immunity

authors： de Azavedo JC,Foster TJ,Hartigan PJ,Arbuthnott JP,O'Reilly M,Kreiswirth BN,Novick RP

更新日期：1985-10-01 00:00:00

abstract：:The purpose of the present study was to evaluate the effectiveness of an attenuated Salmonella enterica serovar Typhimurium vaccine strain expressing the saliva-binding region (SBR) of the Streptococcus mutans antigen I/II adhesin, either alone or linked with the mucosal adjuvant cholera toxin A2 and B subunits (CTA2/...

journal_title：Infection and immunity

authors： Huang Y,Hajishengallis G,Michalek SM

更新日期：2001-04-01 00:00:00

abstract：:Expression of virulence determinants by Bordetella pertussis, the primary etiological agent of whooping cough, is regulated by the BvgAS two-component regulatory system. The role of a second two-component regulatory system, encoded by risAS, in this process is not defined. Here, we show that mutation of B. pertussis r...

journal_title：Infection and immunity

authors： Stenson TH,Allen AG,Al-Meer JA,Maskell D,Peppler MS

更新日期：2005-09-01 00:00:00

abstract：:Four strains of Staphylococcus aureus of a phage type other than the second group, isolated from patients with impetigo and Ritter's disease, were found to produce an exotoxin similar to those reported by Melish et al. (1972), Kapral and Miller (1971), and Arbuthnott et al. (1973). This toxin could elicit a general ex...

journal_title：Infection and immunity

authors： Kondo I,Sakurai S,Sarai Y

更新日期：1974-10-01 00:00:00

abstract：:Bacillus cereus causes exotoxin-mediated diarrheal food poisoning. Hemolysin BL (HBL) is a well-characterized B. cereus toxin composed of three components (B, L1, and L2) that together possess hemolytic, cytotoxic, dermonecrotic, and vascular permeability activities. Here, we show that HBL causes fluid accumulation in...

journal_title：Infection and immunity

authors： Beecher DJ,Schoeni JL,Wong AC

更新日期：1995-11-01 00:00:00

abstract：:The attachment of isogenic fimbriated and nonfimbriated Haemophilus influenzae type b variants to human cells was studied by using a radioactive assay and an indirect immunofluorescent assay. As described previously, fimbriated H. influenzae variants adhered to a greater extent than nonfimbriated variants to human buc...

journal_title：Infection and immunity

authors： Sable NS,Connor EM,Hall CB,Loeb MR

更新日期：1985-04-01 00:00:00

abstract：:The application of dissociation techniques, involving gel filtration in the presence of guanidine, to a semipurified preparation of Campylobacter jejuni heat-labile enterotoxin yielded a material whose functional and immunological properties resemble those of the B subunits of cholera toxin and Escherichia coli heat-l...

journal_title：Infection and immunity

authors： Klipstein FA,Engert RF

更新日期：1985-06-01 00:00:00