Immunoglobulin G and M composition of naturally occurring antibody to type III group B streptococci.

abstract：:The epitope specificities of 13 hybridomas secreting monoclonal antibodies (MAbs) specific for pertussis toxin (PT) is described. Hybridoma lines were derived by the fusion of spleen cells from mice immunized with native PT, Formalin-detoxified PT, or isolated PT subunits (S1 to S5) with the myeloma line X63-Ag8.653. ...

journal_title：Infection and immunity

authors： Lang AB,Ganss MT,Cryz SJ Jr

更新日期：1989-09-01 00:00:00

abstract：:Escherichia coli is a versatile pathogen causing millions of infections in humans every year. This bacterium can form multicellular aggregates when it expresses a self-associating protein, antigen 43 (Ag43), on its surface. We have discovered that Ag43-expressing E. coli cells are efficiently taken up by human defense...

journal_title：Infection and immunity

authors： Fexby S,Bjarnsholt T,Jensen PØ,Roos V,Høiby N,Givskov M,Klemm P

更新日期：2007-01-01 00:00:00

abstract：:Mice infected with various strains of Salmonella enteritidis and S. typhimurium were found to be more sensitive to the cell wall lipopolysaccharide (LPS) extracted from certain strains of Salmonella than noninfected mice. This hypersensitivity was induced by those smooth or rough strains which possessed a polysacchari...

journal_title：Infection and immunity

authors： Kawakami M,Hara Y,Osawa N

更新日期：1971-11-01 00:00:00

abstract：:Virulent Treponema pallidum organisms, extracted from infected rabbit testes, were subjected to velocity sedimentation in discontinuous gradients of Hypaque, a high density, low viscosity material. After centrifugation of extracts at 20 C for 45 min at 100,000 x g, treponemes separated into two distinct bands based up...

journal_title：Infection and immunity

authors： Baseman JB,Nichols JC,Rumpp JW,Hayes NS

更新日期：1974-11-01 00:00:00

abstract：:Lymphocyte blastogenesis assays and immunoblotting were used to investigate and compare murine B-cell responses to preparations of extracellular membrane blebs (BAg) and spirochetes (Ag) of Borrelia burgdorferi. Immunoblotting BAg, Ag, and medium control preparations with serum from naive and infected C57BL/10 mice re...

journal_title：Infection and immunity

authors： Whitmire WM,Garon CF

更新日期：1993-04-01 00:00:00

abstract：:The development of immunoglobulin-containing cells and antigen-specific plasma cells in retropharyngeal and bronchial lymph nodes, in lung tissue, and in nasal mucous membrane was followed during an experimental infection of pigs with Mycoplasma hyopneumoniae. An enzyme-linked immunosorbent assay was used to follow st...

journal_title：Infection and immunity

authors： Suter M,Kobisch M,Nicolet J

更新日期：1985-09-01 00:00:00

abstract：:Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent approach, using multiple-antigen vaccines (MAV) prepared from S. pneumoniae TIGR4...

journal_title：Infection and immunity

authors： Chan WY,Entwisle C,Ercoli G,Ramos-Sevillano E,McIlgorm A,Cecchini P,Bailey C,Lam O,Whiting G,Green N,Goldblatt D,Wheeler JX,Brown JS

更新日期：2019-02-21 00:00:00

abstract：:The three most abundant extracellular proteins of Mycobacterium tuberculosis, the 30-, 32-, and 16-kDa major extracellular proteins, are particularly promising vaccine candidates. We have mapped T-cell epitopes of these three proteins in outbred guinea pigs by immunizing the animals with each protein and assaying sple...

journal_title：Infection and immunity

authors： Lee BY,Horwitz MA

更新日期：1999-05-01 00:00:00

abstract：:Infection of CFW mice with Trichinella spiralis induced a state of relative unresponsiveness to passive cutaneous anaphylaxis (PCA) induced with hen egg albumin and its corresponding antibodies. The unresponsiveness was to PCA produced either with immunoglobulin G1 (IgG1) or IgE type of antibodies, but was more pronou...

journal_title：Infection and immunity

authors： Munoz JJ,Cole RL

更新日期：1977-01-01 00:00:00

abstract：:Activation of macrophages was assessed in strains of mice inoculated intraperitoneally with 1,000 times the 50% lethal dose of Rickettsia akari. Macrophages from mice resistant to R. akari infection (C3H/HeN, C57BL/10J, and BALB/cN) were nonspecifically tumoricidal 2 to 4 days after rickettsial inoculation. Moreover, ...

journal_title：Infection and immunity

authors： Nacy CA,Meltzer MS

更新日期：1982-06-01 00:00:00

abstract：:Host control of Coxiella burnetii infections is believed to be mediated primarily by activated monocytes/macrophages. The activation of macrophages by cytokines leads to the production of reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI) that have potent antimicrobial activities. The contri...

journal_title：Infection and immunity

authors： Brennan RE,Russell K,Zhang G,Samuel JE

更新日期：2004-11-01 00:00:00

abstract：:Neisseria gonorrhoeae, the etiologic agent of gonorrhea, is frequently asymptomatic in women, often leading to chronic infections. One factor contributing to this may be biofilm formation. N. gonorrhoeae can form biofilms on glass and plastic surfaces. There is also evidence that biofilm formation may occur during nat...

journal_title：Infection and immunity

authors： Falsetta ML,Bair TB,Ku SC,Vanden Hoven RN,Steichen CT,McEwan AG,Jennings MP,Apicella MA

更新日期：2009-09-01 00:00:00

abstract：:In an attempt to clarify the mechanism(s) of increased susceptibility to oral infection in diabetics, we examined the levels of salivary antibacterial factors, including lysozyme, lactoperoxidase, and lactoferrin, in diabetic hamsters whose condition was induced with streptozotocin. Saliva was collected from these ham...

journal_title：Infection and immunity

authors： Muratsu K,Morioka T

更新日期：1985-05-01 00:00:00

abstract：:Bacterial products from gram-positive bacteria, such as peptidoglycan, teichoic acid, and toxins, activate mononuclear cells to produce tumor necrosis factor alpha (TNF). The present study evaluated the release of soluble cell wall components from Staphylococcus epidermidis capable of inducing TNF after exposure of th...

journal_title：Infection and immunity

authors： Mattsson E,Van Dijk H,Verhoef J,Norrby R,Rollof J

更新日期：1996-10-01 00:00:00

abstract：:A significant depression in the phagocytic capacity of elicited peritoneal macrophages, pulmonary alveolar macrophages, and elicited peritoneal polymorphonucleated neutrophils was manifested when the cells were incubated in medium containing cadmium chloride. With the exception of the neutrophils, a similar influence ...

journal_title：Infection and immunity

authors： Loose LD,Silkworth JB,Simpson DW

更新日期：1978-11-01 00:00:00

abstract：:The type III secretion system (TTSS) of Pseudomonas aeruginosa is induced in vivo upon contact with eukaryotic cells and in vitro by calcium depletion in culture medium. We have observed a previously identified protein, PsrA, necessary for full activation of TTSS gene expression in P. aeruginosa. Electrophoretic mobil...

journal_title：Infection and immunity

authors： Shen DK,Filopon D,Kuhn L,Polack B,Toussaint B

更新日期：2006-02-01 00:00:00

abstract：:Escherichia coli O157:H7 causes food and waterborne enteric infections that can result in hemorrhagic colitis and life-threatening hemolytic uremic syndrome. Intimate adherence of the bacteria to intestinal epithelial cells is mediated by intimin, but E. coli O157:H7 also possess several other putative adhesins, inclu...

journal_title：Infection and immunity

authors： Lloyd SJ,Ritchie JM,Rojas-Lopez M,Blumentritt CA,Popov VL,Greenwich JL,Waldor MK,Torres AG

更新日期：2012-03-01 00:00:00

abstract：:The adherence of Treponema denticola GM-1, TD-4, and MS25 to human gingival fibroblasts (HGFs) was studied to serve as an introduction to investigations into the interactions of these oral bacteria with human host cells. Under both aerobic (5% CO2) and anaerobic (85% N2 plus 10% H2 plus 5% CO2) environments, the inter...

journal_title：Infection and immunity

authors： Weinberg A,Holt SC

更新日期：1990-06-01 00:00:00

abstract：:The influence of the leukotoxin of Pasteurella haemolytica on the generation of arachidonic acid metabolites by bovine polymorphonuclear leukocytes (PMNs) was investigated. PMNs released 5-, 12-, and 15-hydroxyeicosatetraenoic acids (5-, 12-, and 15-HETE) and leukotriene B4 (LTB4) upon stimulation with arachidonic aci...

journal_title：Infection and immunity

authors： Henricks PA,Binkhorst GJ,Drijver AA,Nijkamp FP

更新日期：1992-08-01 00:00:00

abstract：:The development of immunological responsiveness to a soluble cercarial antigenic preparation (CAP) from Schistosoma mansoni was analyzed in inbred CBA/J mice infected with cercariae, one or multiple times, or sensitized using CAP. Repeated exposure to 75 cercariae at three weekly intervals (3X-75) or subcutaneous admi...

journal_title：Infection and immunity

authors： Katz SP,Colley DG

更新日期：1976-08-01 00:00:00

abstract：:Patent filarial infection is associated with the downregulation of parasite-specific immune reactivity. In the present study, the relationship between in vitro parasite antigen-specific humoral and cellular immune responsiveness was investigated in Brugia pahangi-infected jirds and in jirds immunized with soluble anti...

journal_title：Infection and immunity

authors： Prier RC,Lammie PJ

更新日期：1988-12-01 00:00:00

abstract：:Previous studies have demonstrated antigenic differences among the pili expressed by various strains of Haemophilus influenzae type b (Hib). In order to understand the molecular basis for these differences, the structural gene for pilin was cloned from Hib strain Eagan (p+) and the nucleotide sequence was compared to ...

journal_title：Infection and immunity

authors： Forney LJ,Marrs CF,Bektesh SL,Gilsdorf JR

更新日期：1991-06-01 00:00:00

abstract：:Patients with chronic bronchitis are colonized by and may develop acute bronchopulmonary infection due to nontypable Haemophilus influenzae (NTHI) despite the presence of bactericidal and opsonizing antibody to the infecting organism. To test the hypothesis that secretory immunoglobulin A (IgA) interferes with host de...

journal_title：Infection and immunity

authors： Musher DM,Goree A,Baughn RE,Birdsall HH

更新日期：1984-07-01 00:00:00

abstract：:Isolated Bacteroides gingivalis 2561 vesicles aggregated suspensions of Actinomyces viscosus and Actinomyces naeslundii of all taxonomy clusters. Vesicles bound near A. viscosus cell walls and among its surface fibrils. Tritiated vesicles bound slightly better to saliva-coated hydroxyapatite (SHA) than to SHA coated w...

journal_title：Infection and immunity

authors： Ellen RP,Grove DA

更新日期：1989-05-01 00:00:00

abstract：:After aerosol deposition of Serratia marcescens in mice, initial delayed pulmonary clearance was followed between 4 and 24 hr later by progressive elimination. ...

journal_title：Infection and immunity

authors： Southern PM,Pierce AK,Sanford JP

更新日期：1971-01-01 00:00:00

abstract：:Host-driven macrophage apoptosis contributes to innate immunity during bacterial infection. Neisseria meningitidis inhibits apoptosis in a variety of cells, but its impact on macrophage apoptosis is unknown. We demonstrate that N. meningitidis prevents macrophage apoptosis via genes encoding nitric oxide detoxificatio...

journal_title：Infection and immunity

authors： Tunbridge AJ,Stevanin TM,Lee M,Marriott HM,Moir JW,Read RC,Dockrell DH

更新日期：2006-01-01 00:00:00

abstract：:Optimal protective immunity against babesial infection is postulated to require both complement-fixing and opsonizing antibodies in addition to gamma interferon (IFN-gamma)-mediated macrophage activation. The rhoptry-associated protein 1 (RAP-1) of Babesia bigemina induces partial protective immunity and is a candidat...

journal_title：Infection and immunity

authors： Brown WC,McElwain TF,Palmer GH,Chantler SE,Estes DM

更新日期：1999-01-01 00:00:00

abstract：:Escherichia coli strains isolated from newborn infants were injected intraperitoneally into infant rats. Strains possessing the K1 capsular polysaccharide antigen were significantly more virulent than strains lacking this antigen. When 5-day-old animals were injected with 1.2 X 10(1) colony forming units of a K1 E. co...

journal_title：Infection and immunity

authors： Bortolussi R,Ferrieri P,Wannamaker LW

更新日期：1978-11-01 00:00:00

abstract：:The role of macrophages in protecting mice from murine cytomegalovirus (MCMV) was studied in Swiss, CBA/J, and C57BL/6J mice. CBA/J mice were more resistant to virus than were C57BL/6J mice at all ages tested. Prior treatment of adult Swiss mice with 60 mg of silica, a dose selectively toxic to macrophages, increased ...

journal_title：Infection and immunity

authors： Selgrade MK,Osborn JE

更新日期：1974-12-01 00:00:00

abstract：:Adherence to fibrinogen and fibronectin plays a crucial role in Staphylococcus aureus experimental endocarditis. Previous genetic studies have shown that infection and carriage isolates do not systematically differ in their virulence-related genes, including genes conferring adherence, such as clfA and fnbA. We set ou...

journal_title：Infection and immunity

authors： Ythier M,Entenza JM,Bille J,Vandenesch F,Bes M,Moreillon P,Sakwinska O

更新日期：2010-04-01 00:00:00