Both inducible nitric oxide synthase and NADPH oxidase contribute to the control of virulent phase I Coxiella burnetii infections.

abstract：:Shiga toxin type 1 (Stx1) belongs to the Shiga family of bipartite AB toxins that inactivate eukaryotic 60S ribosomes. The A subunit of Stxs are N-glycosidases that share structural and functional features in their catalytic center and in an internal hydrophobic region that shows strong transmembrane propensity. Both ...

journal_title：Infection and immunity

authors： Suhan ML,Hovde CJ

更新日期：1998-11-01 00:00:00

abstract：:Naturally occurring antibodies for Vibrio fetus with whole-cell and O antigen specificities were detected in sera of mature cattle by means of the agglutination and indirect immunofluorescence reactions. O antibodies occurred in each of 21 sera examined, and whole-cell antibodies, in lower concentrations, occurred in ...

journal_title：Infection and immunity

authors： Duncan JR,Wilkie BN,Winter AJ

更新日期：1972-05-01 00:00:00

abstract：:3-O-methylmannose isolated from Coccidioides immitis was characterized by gas chromatographic comparison of derivatives with those of synthetic 3-O-methylmannose. Gas chromatographic behavior of three derivatives of the natural and synthetic sugars was identical. ...

journal_title：Infection and immunity

authors： Porter JF,Scheer ER,Wheat RW

更新日期：1971-11-01 00:00:00

abstract：:The response of ferrets after intranasal inoculation of inactivated A/Hong Kong/68 (H3N2) influenza virus vaccines is reported. Normal ferrets given either saline vaccine in drops or freeze-dried vaccine in an aerosol intranasally did not produce detectable serum or nasal hemagglutination inhibiting antibody and were ...

journal_title：Infection and immunity

authors： McLaren C,Potter CW,Jennings R

更新日期：1974-06-01 00:00:00

abstract：:Previously, in our laboratory, we established a two-chamber system to study translocation of Enterococcus faecalis across monolayers of polarized human colon carcinoma-derived T84 cells. By using the same system in the present study, we now show that disruption of gelE of strain OG1RF, which also has a polar effect on...

journal_title：Infection and immunity

authors： Zeng J,Teng F,Murray BE

更新日期：2005-03-01 00:00:00

abstract：:Acquired cellular immunity to infection with Mycobacterium tuberculosis is believed to reside in the capacity of mononuclear phagocytes of immunized animals to inhibit intracellular multiplication of the parasite. However, in macrophage tissue culture systems, it has been customary to employ streptomycin in the medium...

journal_title：Infection and immunity

authors： Patterson RJ,Youmans GP

更新日期：1970-01-01 00:00:00

abstract：:Four isolates of Staphylococcus aureus from patients with endocarditis and bacteremia were capable of secreting high-molecular-weight soluble peptidoglycans when grown in a minimal cell wall medium containing penicillin G. Vancomycin was not able to substitute for penicillin G in triggering this secretion. Secretion r...

journal_title：Infection and immunity

authors： Zeiger AR,Wong W,Chatterjee AN,Young FE,Tuazon CU

更新日期：1982-09-01 00:00:00

abstract：:Enteropathogenic Escherichia coli (EPEC) interacts with intestinal epithelial cells, activating host signaling pathways leading to cytoskeletal rearrangements and ultimately diarrhea. In this study, we demonstrate that EPEC interacts with the macrophage-like cell line J774A.1 to inhibit phagocytosis by these cells. An...

journal_title：Infection and immunity

authors： Goosney DL,Celli J,Kenny B,Finlay BB

更新日期：1999-02-01 00:00:00

abstract：:The invasion of Rickettsia tsutsugamushi, Gilliam strain, into guinea pig polymorphonuclear leukocytes (PMNs) and the localization and distribution of tracers were followed during the process by electron microscopy. The seven tracers used were: cationized ferritin, ferritin, thorium dioxide (ThO2), carbon particles, l...

journal_title：Infection and immunity

authors： Rikihisa Y,Ito S

更新日期：1980-10-01 00:00:00

abstract：:The primary antibody response of BALB/c splenocytes to sheep erythrocytes in vitro was suppressed by infection with Friend leukemia virus (FLV), with the response capacity decreasing with increasing duration of infection. The acquisition of normal antibody responses was amplified by macrophage-produced antibody respon...

journal_title：Infection and immunity

authors： Butler RC,Frier JM,Chapekar MS,Graham MO,Friedman H

更新日期：1983-03-01 00:00:00

abstract：:V beta 10(+) and V beta 14(+) T cells were selectively increased 7 to 14 days following infection in the lungs of naive mice infected with Histoplasma capsulatum. Following secondary challenge of immune mice, V beta 1(+) and V beta 8.1(+) cells were sporadically increased. Elimination of V beta 10(+) and V beta 14(+) ...

journal_title：Infection and immunity

authors： Deepe GS Jr,Gibbons RS,Ward SR

更新日期：2002-03-01 00:00:00

abstract：:In an effort to relate the protein profile to virulence, proteins from the cellular fractions and from culture supernatants of Streptococcus suis capsular type 2 strains from different geographical origins were compared by using Western blots (immunoblots). The protein profiles of the cellular fractions were similar f...

journal_title：Infection and immunity

authors： Quessy S,Dubreuil JD,Caya M,Higgins R

更新日期：1995-05-01 00:00:00

abstract：:A solid-phase radioimmunoassay method has been developed for the detection of rotavirus in the form of a purified antigen and in stool. The parameters of the radioimmunoassay were examined and optimized to give high sensitivity and same-day results. Compared with electron microscopy, the assay is up to 10 times as sen...

journal_title：Infection and immunity

authors： Middleton PJ,Holdaway MD,Petric M,Szymanski MT,Tam JS

更新日期：1977-05-01 00:00:00

abstract：:Antigen-presenting cells (APCs) are key players in the induction and regulation of immune responses. In Plasmodium falciparum malaria, determination of which cells and pathways are activated in the network of APCs remains elusive. We therefore investigated the effects of a controlled human malaria infection in healthy...

journal_title：Infection and immunity

authors： Teirlinck AC,Roestenberg M,Bijker EM,Hoffman SL,Sauerwein RW,Scholzen A

更新日期：2015-09-01 00:00:00

abstract：:Endotoxin-treated mice exhibit a rapid rise in the level of the serum amyloid A (SAA) protein, but this effect is not observed in endotoxin-resistant C3H/HeJ mice. To evaluate the role of lymphoid cells in the production of SAA protein, C3H/HeJ mice were adoptively transfused with endotoxin-sensitive (C3H/HeN) bone ma...

journal_title：Infection and immunity

authors： Rosenstreich DL,McAdam KP

更新日期：1979-01-01 00:00:00

abstract：:B cell activating factor of the tumor necrosis factor family (BAFF) is an essential survival factor for B cells and has been shown to regulate T cell-independent (TI) IgM production. During Ehrlichia muris infection, TI IgM secretion in the spleen was BAFF dependent, and antibody-mediated BAFF neutralization led to an...

journal_title：Infection and immunity

authors： Jones DD,Jones M,DeIulio GA,Racine R,MacNamara KC,Winslow GM

更新日期：2013-12-01 00:00:00

abstract：:Specific proteolytic destruction of the human chemotaxin, C5a, is a property of group A and B streptococcal pathogens. Here we show that virulent group G streptococci from human sources also express C5a peptidase activity. The enzyme responsible for this activity is approximately the same size as and is antigenically ...

journal_title：Infection and immunity

authors： Cleary PP,Peterson J,Chen C,Nelson C

更新日期：1991-07-01 00:00:00

abstract：:A Gram-negative, filamentous, rod-shaped bacillus which failed to grow in cell-free media was isolated in apparently pure culture from the bronchial scraping and washing of a laboratory rat suffering from chronic respiratory disease by inoculating embryonated chicken eggs via the allantoic route. None of the embryos d...

journal_title：Infection and immunity

authors： Ganaway JR,Spencer TH,Moore TD,Allen AM

更新日期：1985-02-01 00:00:00

abstract：:Screening of a Mycobacterium tuberculosis genomic DNA library in the lambda gt11 expression vector was carried out by using, as probes, sera from tuberculous patients and murine monoclonal antibody H61.3 recognizing a mycobacterial 35-kilodalton protein present only on the M. tuberculosis complex. The recombinant beta...

journal_title：Infection and immunity

authors： Vismara D,Mezzopreti MF,Gilardini Montani MS,Del Porto P,Lombardi G,Piccolella E,Damiani G,Rappuoli R,Colizzi V

更新日期：1990-01-01 00:00:00

abstract：:Membrane and soluble fractions of Mycoplasma pneumoniae, M. pulmonis, and M. laidlawii B were prepared by hypotonic lysis of whole cells. The membranes of M. pneumoniae and M. laidlawii B contained, as percentage of dry weight: 34 to 37% protein, 59 to 61% lipid, 3 to 4% carbohydrate as hexose, and 0.2% ribonucleic ac...

journal_title：Infection and immunity

authors： Pollack JD,Somerson NL,Senterfit LB

更新日期：1970-09-01 00:00:00

abstract：:Both interleukin-17A (IL-17A) and IL-17F are proinflammatory cytokines that have an important role in intestinal homeostasis via receptor signaling. These cytokines have been characterized in chickens, but very little is known about their receptors and their functional activity. We provide here the first description o...

journal_title：Infection and immunity

authors： Kim WH,Jeong J,Park AR,Yim D,Kim S,Chang HH,Yang SH,Kim DH,Lillehoj HS,Min W

更新日期：2014-09-01 00:00:00

abstract：:Nonviable Mycobacterium tuberculosis strain Jamaica suspended in oil-droplet emulsions was used to enhance resistance of mice against encephalomyocarditis virus (EMCV). The mycobacteria-injected mice were significantly resistant to 50,000 50% lethal doses of EMCV. Similar concentrations of virus in plasma of normal an...

journal_title：Infection and immunity

authors： Lodmell DL,Ewalt LC

更新日期：1978-12-01 00:00:00

abstract：:Staphylococcus aureus and Salmonella enterica serovar Dublin invade osteoblasts and are causative agents of human bone disease. In the present study, we examined the ability of S. aureus and Salmonella serovar Dublin to induce the production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by normal ...

journal_title：Infection and immunity

authors： Alexander EH,Bento JL,Hughes FM Jr,Marriott I,Hudson MC,Bost KL

更新日期：2001-03-01 00:00:00

abstract：:A hemagglutinin with an M(r) of 67,000 (pMGA) from Mycoplasma gallisepticum S6 was purified by using monoclonal antibody affinity chromatography. Purified pMGA was treated with a number of enzymes, the resultant peptides were purified, and their amino acid sequence was determined by using an Applied Biosystems (model ...

journal_title：Infection and immunity

authors： Markham PF,Glew MD,Whithear KG,Walker ID

更新日期：1993-03-01 00:00:00

abstract：:Although recent evidence suggests that fibronectin may be involved in the attachment of treponemes to mammalian cells, its possible role in promoting phagocytosis of Treponema pallidum has not been investigated. In the present study, we examined the antibody-independent interactions of fibronectin, C1q, and human poly...

journal_title：Infection and immunity

authors： Baughn RE

更新日期：1986-11-01 00:00:00

abstract：:Antigen-specific T-cell responses and histopathological changes were studied in mice experimentally inoculated with Borrelia burgdorferi B31. Inbred mice with different H-2 haplotypes and/or different genetic backgrounds were inoculated with B. burgdorferi organisms and tested for antigen-specific T-cell responses in ...

journal_title：Infection and immunity

authors： Schaible UE,Kramer MD,Justus CW,Museteanu C,Simon MM

更新日期：1989-01-01 00:00:00

abstract：:The surface antigen makeup of metacyclic trypomastigote forms of strain G of Trypanosoma cruzi, which produce a subpatent infection in mice, differed from those of the virulent strains Y and CL. A 100,000-molecular-weight protein, barely detectable on the Y or CL cell surface, appeared as the main surface antigen of t...

journal_title：Infection and immunity

authors： Yoshida N

更新日期：1983-05-01 00:00:00

abstract：:Amastigotes obtained from spleens of mice infected with different strains of Trypanosoma cruzi were examined for their ability to invade macrophages and L929 cells and to initiate infection in mice. Both types of cells were readily invaded by organisms of the strains Y, MR, and Tulahuen. Organisms of the CL strain wer...

journal_title：Infection and immunity

authors： McCabe RE,Remington JS,Araujo FG

更新日期：1984-11-01 00:00:00

abstract：:The cell surface hydrophobicity of 10 pigmented and 4 nonpigmented clinical Serratia marcescens strains was studied, based on the ability of the strains to adhere to hydrocarbons and to polystyrene. The cell surface hydrophobicity depended greatly on growth temperature; all of the strains tested were adherent followin...

journal_title：Infection and immunity

authors： Rosenberg M,Blumberger Y,Judes H,Bar-Ness R,Rubinstein E,Mazor Y

更新日期：1986-03-01 00:00:00

abstract：:Streptococcus pneumoniae is a major cause of pneumonia and meningitis. Airway colonization is a necessary precursor to disease, but little is known about how the bacteria establish and maintain colonization. Carbohydrates are required as a carbon source for pneumococcal growth and, therefore, for colonization. Free ca...

journal_title：Infection and immunity

authors： Marion C,Burnaugh AM,Woodiga SA,King SJ

更新日期：2011-03-01 00:00:00