Abstract:
:V beta 10(+) and V beta 14(+) T cells were selectively increased 7 to 14 days following infection in the lungs of naive mice infected with Histoplasma capsulatum. Following secondary challenge of immune mice, V beta 1(+) and V beta 8.1(+) cells were sporadically increased. Elimination of V beta 10(+) and V beta 14(+) cells from naive mice did not alter the course of infection over a period of 21 days. Thus, overexpression of V beta families does not necessarily signify a key role in host defense.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Deepe GS Jr,Gibbons RS,Ward SRdoi
10.1128/iai.70.3.1648-1652.2002keywords:
subject
Has Abstractpub_date
2002-03-01 00:00:00pages
1648-52issue
3eissn
0019-9567issn
1098-5522journal_volume
70pub_type
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journal_title:Infection and immunity
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journal_title:Infection and immunity
pub_type: 杂志文章
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journal_title:Infection and immunity
pub_type: 杂志文章
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