Biofilm formation enhances fomite survival of Streptococcus pneumoniae and Streptococcus pyogenes.

abstract：:Pregnant mice, guinea pigs, rats, and rabbits responded to injections of Moraxella bovis strain EPP-63(300) with abortion, death, embryo resorption, and production of small litters. The nature of response appeared to depend primarily on the number of viable cells injected and to some extent on the species of animal an...

journal_title：Infection and immunity

authors： Norman JO,Elissalde MH

更新日期：1979-05-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is an inflammatory disease that has been linked to several risk factors, including periodontitis. Identification of new anti-inflammatory compounds to treat arthritis is needed. We had previously demonstrated the beneficial effect of Kava-241, a kavain-derived compound, in the management of P...

journal_title：Infection and immunity

authors： Huck O,You J,Han X,Cai B,Panek J,Amar S

更新日期：2018-08-22 00:00:00

abstract：:Tularemia is caused by the Gram-negative bacterial pathogen Francisella tularensis Infection of macrophages and their subsequent death are believed to play important roles in the progression of disease. Because complement is a particularly effective opsonin for Francisella, we asked whether complement-dependent uptake...

journal_title：Infection and immunity

authors： Brock SR,Parmely MJ

更新日期：2017-09-20 00:00:00

abstract：:The immunoprophylactic effect of chemically inactivated Pseudomonas aeruginosa exotoxin A in experimental pseudomonas infections was studied. Exotoxin A toxoids were prepared by Formalin (f-TXD) or glutaraldehyde (g-TXD) treatment. Immunization of mice with three or four doses (10 micrograms each) of f-TXD and the syn...

journal_title：Infection and immunity

authors： Pavlovskis OR,Edman DC,Leppla SH,Wretlind B,Lewis LR,Martin KE

更新日期：1981-05-01 00:00:00

abstract：:The recent development of acellular pertussis vaccines has been a significant improvement in the conventional whole-cell diphtheria-pertussis-tetanus toxoid vaccines, but high production costs will limit its widespread use in developing countries. Since Mycobacterium bovis BCG vaccination against tuberculosis is used ...

journal_title：Infection and immunity

authors： Nascimento IP,Dias WO,Mazzantini RP,Miyaji EN,Gamberini M,Quintilio W,Gebara VC,Cardoso DF,Ho PL,Raw I,Winter N,Gicquel B,Rappuoli R,Leite LC

更新日期：2000-09-01 00:00:00

abstract：:The mouse system provides an excellent model for studying host resistance to Naegleria fowleri, the agent of primary amoebic meningoencephalitis. Innate resistance to infection with N. fowleri was examined with respect to infecting dose and the age, sex, and strain of mice. Intravenous inoculation with 10(7) amoebae p...

journal_title：Infection and immunity

authors： Haggerty RM,John DT

更新日期：1978-04-01 00:00:00

abstract：:Antibody to Pseudomonas aeruginosa exotoxin was detected in human sera by using a cytotoxicity-neutralization assay. Serum antitoxin was present in high titer in all 14 patients who recovered from serious pseudomonas infections (log2 of 50% neutralization titer, mean +/- standard deviation = 6.0 +/- 1.2). In contrast,...

journal_title：Infection and immunity

authors： Pollack M,Callahan LT 3rd,Taylor NS

更新日期：1976-10-01 00:00:00

abstract：:Analysis of the partition in a two-polymer phase system of Salmonella typhimurium R mutants with different susceptibility to phagocytosis distinguished between the mutants. Close to 80% of the R mutants least resistant to phagocytosis accumulated in the dextran-rich phase, whereas more phagocytosis-resistant mutants s...

journal_title：Infection and immunity

authors： Stendahl O,Tagesson C,Edebo M

更新日期：1973-07-01 00:00:00

abstract：:The serum antibody response to proteins encoded by the virulence-associated plasmid of Shigella flexneri was determined in monkeys challenged with virulent S. flexneri serotype 2a. With water-extractable antigen in an enzyme-linked immunosorbent assay, a significant increase in antibody titer against proteins from a p...

journal_title：Infection and immunity

authors： Oaks EV,Hale TL,Formal SB

更新日期：1986-07-01 00:00:00

abstract：:Cytoadherence-linked asexual gene 9 (Clag9), a conserved Plasmodium protein expressed during the asexual blood stages, is involved in the cytoadherence of infected red blood cells (RBCs) to the endothelial lining of blood vessels. Here, we show that Plasmodium falciparum Clag9 (PfClag9) is a component of the PfClag9-R...

journal_title：Infection and immunity

authors： Chourasia BK,Deshmukh A,Kaur I,Paul G,Panda A,Rathore S,Singh SK,Theisen M,Mohmmed A,Malhotra P

更新日期：2020-01-22 00:00:00

abstract：:The selC tRNA gene is a common site for the insertion of pathogenicity islands in a variety of bacterial enteric pathogens. We demonstrate here that Escherichia coli that produces Shiga toxin 2d and does not harbor the locus of enterocyte effacement (LEE) contains, instead, a novel genomic island. In one representativ...

journal_title：Infection and immunity

authors： Schmidt H,Zhang WL,Hemmrich U,Jelacic S,Brunder W,Tarr PI,Dobrindt U,Hacker J,Karch H

更新日期：2001-11-01 00:00:00

abstract：:The production of delta-toxin is supposed to be responsible for various pathophysiological effects during infection with Staphylococcus aureus. We compared the effects of delta-toxin with the structurally related bee venom toxin melittin on granulocyte functions and inflammatory mediator release. Delta-toxin and melit...

journal_title：Infection and immunity

authors： Kasimir S,Schönfeld W,Alouf JE,König W

更新日期：1990-06-01 00:00:00

abstract：:Transposon Tn916 was used to insertionally inactivate a coaggregation-relevant locus of Streptococcus gordonii DL1 (Challis). One mutant (F11) was isolated that lost the ability to coaggregate with the streptococcal partners of DL1 but retained the ability to coaggregate with partners belonging to other genera. A prob...

journal_title：Infection and immunity

authors： Whittaker CJ,Clemans DL,Kolenbrander PE

更新日期：1996-10-01 00:00:00

abstract：:Members of our group reported recently that neisseria infection of human epithelial cells results in accelerated degradation of the major lysosomal integral membrane protein LAMP1 and that this is due to hydrolysis of this glycoprotein at its immunoglobulin A1 (IgA1)-like hinge by the neisseria type 2 IgA1 protease (L...

journal_title：Infection and immunity

authors： Ayala P,Lin L,Hopper S,Fukuda M,So M

更新日期：1998-10-01 00:00:00

abstract：:A procedure is described for isolating a high-molecular-weight polysaccharide (PS) from the slime of Pseudomonas aeruginosa immunotype 1. The resultant material, obtained from the void volume of a Sephadex G-100 column, was composed of carbohydrate and water. No lipopolysaccharide (LPS), 2-keto-3-deoxyoctonoate, hepto...

journal_title：Infection and immunity

authors： Pier GB,Sidberry HF,Zolyomi S,Sadoff JC

更新日期：1978-12-01 00:00:00

abstract：:A complex of trehalose-6, 6'-dimycolate (cord factor) and methylated bovine serum albumin was prepared, and its effect on the toxicity of cord factor in mice was studied. Either the active immunization with cord factor-methylated bovine serum albumin complex or the passive transfer of sera of rabbits vaccinated with t...

journal_title：Infection and immunity

authors： Kato M

更新日期：1972-02-01 00:00:00

abstract：:We have previously identified two K88ac adhesion receptors (210 and 240 kDa) which are present in membrane preparations from adhesive but not nonadhesive porcine intestinal brush border cells; these adhesin receptors are postulated to be important determinants of the susceptibility of pigs to K88ac+ enterotoxigenic Es...

journal_title：Infection and immunity

authors： Erickson AK,Baker DR,Bosworth BT,Casey TA,Benfield DA,Francis DH

更新日期：1994-12-01 00:00:00

abstract：:Complement-fixing antibodies were first detected in mice 7 days after intravenous injection with Mycoplasma arthritidis. Peak titers were observed at 21 days, and high levels of antibody persisted through 293 days. The metabolism-inhibiting antibody response was minimal. On fractionation of mouse sera, only 7S antibod...

journal_title：Infection and immunity

authors： Coke BC,Ward JR,Golightly-Rowland C,Trapp GA

更新日期：1971-10-01 00:00:00

abstract：:Mice with a null deletion mutation in the gamma interferon (IFN-gamma) receptor gene were used to study the role of IFN-gamma responsiveness during experimental pulmonary cryptococcosis. Cryptococcus neoformans was inoculated intratracheally into mice lacking the IFN-gamma receptor gene (IFN-gammaR-/-) and into contro...

journal_title：Infection and immunity

authors： Chen GH,McDonald RA,Wells JC,Huffnagle GB,Lukacs NW,Toews GB

更新日期：2005-03-01 00:00:00

abstract：:Experimental Helicobacter pylori infection was studied in Mongolian gerbils with fresh human isolates that carry or do not carry cagA (cagA-positive or cagA-negative, respectively), multiply passaged laboratory strains, wild-type strain G1.1, or isogenic ureA, cagA, or vacA mutants of G1.1. Animals were sacrificed 1 t...

journal_title：Infection and immunity

authors： Wirth HP,Beins MH,Yang M,Tham KT,Blaser MJ

更新日期：1998-10-01 00:00:00

abstract：:Francisella tularensis is a facultative intracellular bacterial pathogen and the causative agent of tularemia. After infection of macrophages, the organism escapes from its phagosome and replicates to high density in the cytosol, but the bacterial factors required for these aspects of virulence are incompletely define...

journal_title：Infection and immunity

authors： Long ME,Lindemann SR,Rasmussen JA,Jones BD,Allen LA

更新日期：2013-03-01 00:00:00

abstract：:Toxin preparations were obtained by growing Clostridium difficile VPI strain 10463 in 2-liter brain heart infusion dialysis flasks at 37 degrees C for 3 days. The initial step of the purification scheme involved ultrafiltration through an XM-100 membrane filter. Two toxic activities, designated toxins A and B, were se...

journal_title：Infection and immunity

authors： Sullivan NM,Pellett S,Wilkins TD

更新日期：1982-03-01 00:00:00

abstract：:Toll-like receptors and Nod-like receptors (NLR) play an important role in sensing invading microorganisms for pathogen clearance and eliciting adaptive immunity for protection against rechallenge. Nod1 and Nod2, members of the NLR family, are capable of detecting bacterial peptidoglycan motifs in the host cytosol for...

journal_title：Infection and immunity

authors： Loving CL,Osorio M,Kim YG,Nuñez G,Hughes MA,Merkel TJ

更新日期：2009-10-01 00:00:00

abstract：:It was demonstrated that complement-coated sheep erythrocytes bind to Candida albicans cells grown in serum-free RPMI 1640 medium. Testing of purified complement components proved that iC3b and C3d were responsible for the reaction, whereas C3b and C3b-H reacted only slightly if at all. Binding occurred only to C. alb...

journal_title：Infection and immunity

authors： Heidenreich F,Dierich MP

更新日期：1985-11-01 00:00:00

abstract：:A cytoplasmic 75-kDa immunogen from Chlamydia trachomatis serovar L2 has previously been characterized as being similar to the Escherichia coli heat shock protein DnaK. We have localized a linear epitope for one monoclonal antibody specific for C. trachomatis DnaK. By use of a recombinant DNA technique, the epitope wa...

journal_title：Infection and immunity

authors： Birkelund S,Larsen B,Holm A,Lundemose AG,Christiansen G

更新日期：1994-05-01 00:00:00

abstract：:The effect of continuous exposure to 80% oxygen on newborn mice with Ureaplasma urealyticum pneumonia was determined. Mice were inoculated intranasally with either U. urealyticum or sterile broth and then housed in either 80% oxygen or room air (21% oxygen). The mice were sacrificed at either 7 or 14 days after inocul...

journal_title：Infection and immunity

authors： Crouse DT,Cassell GH,Waites KB,Foster JM,Cassady G

更新日期：1990-11-01 00:00:00

abstract：:We have previously identified mgrA (rat) as a regulator of autolysis in Staphylococcus aureus. Besides its effect on autolytic activity, we recently found alterations in the expression of regulator and target virulence genes in the mgrA mutant. Northern analysis and transcription fusion assays showed that inactivation...

journal_title：Infection and immunity

authors： Ingavale S,van Wamel W,Luong TT,Lee CY,Cheung AL

更新日期：2005-03-01 00:00:00

abstract：:F344 rats chronically infected with Ureaplasma parvum develop two distinct profiles: asymptomatic urinary tract infection (UTI) and UTI complicated by struvite urolithiasis. To identify factors that affect disease outcome, we characterized the temporal host immune response during infection by histopathologic analysis ...

journal_title：Infection and immunity

authors： Reyes L,Alvarez S,Allam A,Reinhard M,Brown MB

更新日期：2009-10-01 00:00:00

abstract：:After uptake and retrograde transport pertussis toxin acts by ADP-ribosylating alpha-Gi proteins. We show that uptake via many different receptor proteins followed by retrograde transport and intoxication is not restricted to a particular cell type. The efficiency of cellular intoxication, however, was found to be cel...

journal_title：Infection and immunity

authors： el Bayâ A,Brückener K,Schmidt MA

更新日期：1999-01-01 00:00:00

abstract：:Agglutinogen 1 of Bordetella pertussis strain 353/Z (serotype 1) was separated from protective antigen and histamine-sensitizing factor by starch-block electrophoresis. Most of the agglutinogen 1 migrated towards the cathode in starch-block electrophoresis, although some remained near the origin. Fractions containing ...

journal_title：Infection and immunity

authors： Ross RF,Munoz J

更新日期：1971-02-01 00:00:00