Clearance of Serratia marcescens from Lungs of Normal Mice.

abstract：:Ribosomes of strain NOR-7 of group B Neisseria meningitidis were isolated by a procedure that included treatment of the cells with sodium dodecyl sulfate, disruption in a French pressure cell, and differential centrifugation. These preparations consisted of 66% ribonucleic acid and 24% protein and sedimented as a sing...

journal_title：Infection and immunity

authors： Thomas DW,Weiss E

更新日期：1972-09-01 00:00:00

abstract：:In vivo administration of Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) to mice induced apoptosis before a specific immune response. Apoptosis was associated with the expression of immunoglobulin and Ia on B cells and of CD5 and several markers on T cells. Apoptosis peaked in the spleen and lymph nodes on day 2...

journal_title：Infection and immunity

authors： Isogai E,Isogal H,Kimura K,Fujii N,Takagi S,Hirose K,Hayashi M

更新日期：1996-04-01 00:00:00

abstract：:Antibody rises to various virus subcomponents were measured by enzyme-linked immunosorbent assay in the paired sera of volunteers experimentally infected with human coronavirus 229E group viruses. Most of the antibody made during infection was directed against the virus surface projections, with only small amounts of ...

journal_title：Infection and immunity

authors： Macnaughton MR,Hasony HJ,Madge MH,Reed SE

更新日期：1981-03-01 00:00:00

abstract：:Vaccination with native full-length merozoite surface protein 1 (MSP1) or with recombinant C-terminal peptides protects mice against lethal challenge with virulent malaria parasites. To determine whether other regions of MSP1 can also induce protection, Plasmodium yoelii MSP1 was divided into four separate regions. Ea...

journal_title：Infection and immunity

authors： Tian JH,Kumar S,Kaslow DC,Miller LH

更新日期：1997-08-01 00:00:00

abstract：:Escherichia coli F-18 is a human fecal isolate that makes type 1 fimbriae, encoded by the fim gene cluster, and is an excellent colonizer of the streptomycin-treated mouse intestine. E. coli F-18 fimA::tet, lacking type 1 fimbriae, was constructed by bacteriophage P1 transduction of the fim region of the E. coli K-12 ...

journal_title：Infection and immunity

authors： Sweeney NJ,Klemm P,McCormick BA,Moller-Nielsen E,Utley M,Schembri MA,Laux DC,Cohen PS

更新日期：1996-09-01 00:00:00

abstract：:As reported elsewhere, an enterotoxigenic strain of Escherichia coli serotype O25:K98:NM was epidemiologically incriminated as the etiological agent in a shipboard outbreak of diarrheal illness. This enterotoxigenic E. coli strain and possibly other enteric isolates were found to produce heat-labile toxin and not heat...

journal_title：Infection and immunity

authors： Wachsmuth K,Wells J,Shipley P,Ryder R

更新日期：1979-06-01 00:00:00

abstract：:Bordetella bronchiseptica is a Gram-negative bacterium that infects and causes disease in a wide variety of animals. B. bronchiseptica also infects humans, thereby demonstrating zoonotic transmission. An extensive characterization of human B. bronchiseptica isolates is needed to better understand the distinct genetic ...

journal_title：Infection and immunity

authors： Sukumar N,Nicholson TL,Conover MS,Ganguly T,Deora R

更新日期：2014-04-01 00:00:00

abstract：:A single intradermal administration of recombinant interleukin-7 (IL-7) has been shown to aggravate the course of murine schistosomiasis, to favor the development of Th2-associated antibodies specific for the parasite, and to alter migration kinetics and/or migratory route of the parasite within its vertebrate host. H...

journal_title：Infection and immunity

authors： Wolowczuk I,Nutten S,Roye O,Delacre M,Capron M,Murray RM,Trottein F,Auriault C

更新日期：1999-08-01 00:00:00

abstract：:Cell surface proteins SspA and SspB in Streptococcus gordonii and SpaP in Streptococcus mutans are members of the antigen I/II family of polypeptides produced by oral streptococci. These proteins are adhesins and mediate species-specific binding of cells to a variety of host and bacterial receptors. Here we show that ...

journal_title：Infection and immunity

authors： Love RM,McMillan MD,Jenkinson HF

更新日期：1997-12-01 00:00:00

abstract：:We have isolated full-length cDNAs encoding two distinct types of CuZn superoxide dismutases (SODs) from the filarial nematode parasite Brugia pahangi. The derived amino acid sequences suggested that one class of cDNAs represented a cytoplasmic form of SOD and the second class represented an extracellular (EC) variant...

journal_title：Infection and immunity

authors： Tang L,Ou X,Henkle-Dührsen K,Selkirk ME

更新日期：1994-03-01 00:00:00

abstract：:We measured the microbicidal peptides MCP-1 and MCP-2 in rabbit alveolar macrophages (AM), comparing rabbits pretreated with complete Freund adjuvant with untreated control animals. Levels of MCP-1 increased from 4.7 +/- 0.6 microgram/10(7) resident AM to 13.2 +/- 0.1 microgram/10(7) complete Freund adjuvant-elicited ...

journal_title：Infection and immunity

authors： Lehrer RI,Szklarek D,Selsted ME,Fleischmann J

更新日期：1981-09-01 00:00:00

abstract：:A cysteine-containing peptide motif, EWSPCSVTCG, is found highly conserved in the circumsporozoite protein (CSP) and the thrombospondin-related anonymous protein (TRAP) of all the Plasmodium species analyzed so far and has been shown to be crucially involved in the sporozoite invasion of hepatocytes. We have recently ...

journal_title：Infection and immunity

authors： Bharadwaj A,Sharma P,Joshi SK,Singh B,Chauhan VS

更新日期：1998-07-01 00:00:00

abstract：:Porphyromonas gingivalis is a periodontal pathogen capable of invading primary cultures of normal human gingival epithelial cells (NHGEC). Involvement of P. gingivalis fimbriae in the invasion process was examined. Purified P. gingivalis 33277 fimbriae blocked invasion of this organism into NHGEC in a dose-dependent m...

journal_title：Infection and immunity

authors： Weinberg A,Belton CM,Park Y,Lamont RJ

更新日期：1997-01-01 00:00:00

abstract：:Erythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously shown that a Plasmodium falciparum trophozoite cysteine proteinase, now termed falcipain, is required for hemoglobin degradation, and we have hypothesized that this proteinase is re...

journal_title：Infection and immunity

authors： Salas F,Fichmann J,Lee GK,Scott MD,Rosenthal PJ

更新日期：1995-06-01 00:00:00

abstract：:Yersinia pestis KIM5 was found to be cytotoxic for the IC21 and P388D1 mouse macrophage cell lines, as well as for resident peritoneal macrophages from C57BL/6 mice. Affected cells phagocytosed KIM5 inefficiently, became spherical, detached readily from culture dishes, and retained 51Cr poorly. The cytotoxic effect wa...

journal_title：Infection and immunity

authors： Goguen JD,Walker WS,Hatch TP,Yother J

更新日期：1986-03-01 00:00:00

abstract：:The relative roles of serum factors required for opsonization of type XIV Streptococcus pneumoniae were investigated by means of luminol-enhanced chemiluminescence (CL), bactericidal, and immunofluorescence assays employing adult sera containing high (>1,000 ng of antibody nitrogen per ml) or low (<200 ng of antibody ...

journal_title：Infection and immunity

authors： Gardner SE,Anderson DC,Webb BJ,Stitzel AE,Edwards MS,Spitzer RE,Baker CJ

更新日期：1982-03-01 00:00:00

abstract：:Helicobacter pylori infection is thought to be involved in the development of several gastric diseases. Two H. pylori virulence factors (vacuolating cytotoxin A and cytotoxin-associated gene A) reportedly interact with lipid rafts in gastric epithelial cells. The role of Toll-like receptor (TLR)-mediated signaling in ...

journal_title：Infection and immunity

authors： Lu DY,Chen HC,Yang MS,Hsu YM,Lin HJ,Tang CH,Lee CH,Lai CK,Lin CJ,Shyu WC,Lin FY,Lai CH

更新日期：2012-05-01 00:00:00

abstract：:Periodontitis is a bacterium-induced chronic inflammation that destroys tissues that attach teeth to jaw bone. Pathologically excessive matrix metalloproteinase 8 (MMP-8) is among the key players in periodontal destruction by initiating type I collagen degradation. We studied MMP-8 in Porphyromonas gingivalis-induced ...

journal_title：Infection and immunity

authors： Kuula H,Salo T,Pirilä E,Tuomainen AM,Jauhiainen M,Uitto VJ,Tjäderhane L,Pussinen PJ,Sorsa T

更新日期：2009-02-01 00:00:00

abstract：:To study responses to Mycobacterium leprae antigens, we developed an in vitro model system in which latex particles coated with M. leprae sonic extract (MLSON) antigen were presented to monocytes. Uptake and oxidative response as measured by superoxide production to these antigens were investigated. Phagocytosis of ML...

journal_title：Infection and immunity

authors： Hasan RS,Dockrell HM,Jamil S,Chiang TJ,Hussain R

更新日期：1993-09-01 00:00:00

abstract：:Interactions between bacteria and salivary components are thought to be important in the establishment and ecology of the oral microflora. alpha-Amylase, the predominant salivary enzyme in humans, binds to Streptococcus gordonii, a primary colonizer of the tooth. Previous studies have implicated this interaction in ad...

journal_title：Infection and immunity

authors： Rogers JD,Palmer RJ Jr,Kolenbrander PE,Scannapieco FA

更新日期：2001-11-01 00:00:00

abstract：:Type 1 fimbrial phase-locked mutants of uropathogenic Escherichia coli cystitis isolate F11 were used to assess the role of the invertible element during urinary tract infection. Compared to the wild type, the phase-locked off mutant was attenuated, and constitutive production of type 1 fimbriae by the phase-locked on...

journal_title：Infection and immunity

authors： Snyder JA,Lloyd AL,Lockatell CV,Johnson DE,Mobley HL

更新日期：2006-02-01 00:00:00

abstract：:Escherichia coli O45 isolates associated with swine postweaning diarrhea in Québec were characterized with respect to virulence determinants genetically and investigated for their attaching and effacing (A/E) activities by experimental inoculation of gnotobiotic piglets and by the HEp-2 cell adherence assay. All of 32...

journal_title：Infection and immunity

authors： Zhu C,Harel J,Jacques M,Desautels C,Donnenberg MS,Beaudry M,Fairbrother JM

更新日期：1994-10-01 00:00:00

abstract：:Alpha-2,3-sialyltransferase (Lst) is expressed on the outer membrane of Neisseria gonorrhoeae and Neisseria meningitidis and sialylates surface lipooligosaccharide (LOS), facilitating resistance to complement-mediated killing. The enzyme is constitutively expressed from a single gene (lst) and does not undergo antigen...

journal_title：Infection and immunity

authors： Packiam M,Shell DM,Liu SV,Liu YB,McGee DJ,Srivastava R,Seal S,Rest RF

更新日期：2006-05-01 00:00:00

abstract：:Specific pathogen-free guinea pigs were infected via the respiratory route with viable, attenuated Mycobacterium tuberculosis H37Ra and maintained on purified isocaloric diets. The control diet contained 30% protein (ovalbumin) and 50 ppm of added zinc (50 micrograms/g), the low protein diet contained 10% protein and ...

journal_title：Infection and immunity

authors： McMurray DN,Carlomagno MA,Cumberland PA

更新日期：1983-02-01 00:00:00

abstract：:Human gingival fibroblasts were exposed in culture to cell extracts of different black-pigmented Bacteroides species, and their growth was monitored by determining thymidine uptake and counting cells. Of the Bacteroides species tested (B. gingivalis, B. asaccharolyticus, and B. intermedius), B. gingivalis gave the ext...

journal_title：Infection and immunity

authors： Larjava H,Uitto VJ,Eerola E,Haapasalo M

更新日期：1987-01-01 00:00:00

abstract：:The ability of oral immunization to interfere with the establishment of infection with Helicobacter felis was examined. Groups of Swiss Webster mice were immunized orally with 250 micrograms of Helicobacter pylori recombinant urease (rUrease) and 10 micrograms of cholera toxin (CT) adjuvant, 1 mg of H. felis sonicate ...

journal_title：Infection and immunity

authors： Pappo J,Thomas WD Jr,Kabok Z,Taylor NS,Murphy JC,Fox JG

更新日期：1995-04-01 00:00:00

abstract：:Peptidoglycans of Leptotrichia buccalis ATCC 14201 and ATCC 19616 were isolated by extraction with sodium dodecyl sulfate and subsequent digestion of the sodium dodecyl sulfate-insoluble residue with proteases and alpha-amylase. Cell wall fractions obtained by sodium dodecyl sulfate extraction and protease digestion w...

journal_title：Infection and immunity

authors： Fukuhara H,Umemoto T,Sagawa H,Kato K,Kotani S

更新日期：1983-01-01 00:00:00

abstract：:Restoration of the ability of hypogammaglobulinemic serum to support opsonophagocytosis and intracellular killing of Bacteroides fragilis and Bacteroides thetaiotaomicron by human polymorphonuclear leukocytes was achieved by supplementation with normal human immunoglobulin M, but not with normal human immunoglobulin G...

journal_title：Infection and immunity

authors： Bjornson AB,Bjornson HS,Kitko BP

更新日期：1980-05-01 00:00:00

abstract：:Significant resistance against influenza virus and Mycobacterium tuberculosis infections was induced when trehalose dimycolate from M. tuberculosis or M. bovis but not M. avium was combined with muramyl dipeptide. Trehalose dimycolate from M. tuberculosis, in contrast to that from M. avium, could confer resistance aga...

journal_title：Infection and immunity

authors： Masihi KN,Brehmer W,Lange W,Werner H,Ribi E

更新日期：1985-12-01 00:00:00

abstract：:The concept of translational research, which aims to facilitate the application of basic scientific discoveries in clinical and community settings, is currently in vogue. While there are powerful forces driving this trend, support for translational research must be accompanied by a robust investment in basic science, ...

journal_title：Infection and immunity

authors： Fang FC,Casadevall A

更新日期：2010-02-01 00:00:00