Differential expression and transcriptional analysis of the alpha-2,3-sialyltransferase gene in pathogenic Neisseria spp.

abstract：:Identification of antigenically conserved surface components of Haemophilus ducreyi may facilitate the development of reagents to diagnose and prevent chancroid. A hybridoma derived from a mouse immunized with nontypeable Haemophilus influenzae produced a monoclonal antibody (MAb), designated 3B9, that bound to 35 of ...

journal_title：Infection and immunity

authors： Spinola SM,Griffiths GE,Bogdan J,Menegus MA

更新日期：1992-02-01 00:00:00

abstract：:The immune mechanism by which hamsters acquire resistance to infection with Treponema pertenue, the causative agent of frambesia, or yaws, has not been elucidated. Serum or cells (spleen or lymph node) obtained from hamsters resistant to frambesial infection were transferred to normal syngenic recipients, who are subs...

journal_title：Infection and immunity

authors： Schell RF,Le Frock JL,Babu JP

更新日期：1978-08-01 00:00:00

abstract：:The symptoms of Lyme disease are caused by inflammation induced by species of the Borrelia burgdorferisensu lato complex. The various presentations of Lyme disease in the population suggest that differences exist in the intensity and regulation of the host response to the spirochete. Previous work has described correl...

journal_title：Infection and immunity

authors： Siebers EM,Liedhegner ES,Lawlor MW,Schell RF,Nardelli DT

更新日期：2020-10-19 00:00:00

abstract：:Interstitial lung macrophages from tuberculosis-susceptible I/St and tuberculosis-resistant A/Sn mice demonstrated significant constitutive differences in gene expression levels, whereas in vitro infection of these cells with Mycobacterium tuberculosis had only a modulatory impact on gene expression. We conclude that ...

journal_title：Infection and immunity

authors： Orlova MO,Majorov KB,Lyadova IV,Eruslanov EB,M'lan CE,Greenwood CM,Schurr E,Apt AS

更新日期：2006-06-01 00:00:00

abstract：:Interactions between Yersinia enterocolitica and rabbit ileal mucus were examined. Strains carrying the Yersinia virulence plasmid, pYV, adhered to crude mucus but not to intestinal luminal contents that had been immobilized on polystyrene. Using an Y. enterocolitica O:9 mutant in which the yadA gene (formerly called ...

journal_title：Infection and immunity

authors： Paerregaard A,Espersen F,Jensen OM,Skurnik M

更新日期：1991-01-01 00:00:00

abstract：:The cytopathic effect (CPE) of Escherichia coli producing cytotoxic necrotizing factor type 1 (CNF1) was investigated by using a human epithelial cell (HeLa) model of infection with CNF1-producing E. coli BM2-1. This strain was shown to bind loosely, but massively, to HeLa cells. A 4-h interaction between bacteria and...

journal_title：Infection and immunity

authors： De Rycke J,Mazars P,Nougayrede JP,Tasca C,Boury M,Herault F,Valette A,Oswald E

更新日期：1996-05-01 00:00:00

abstract：:Mice with disrupted beta 2-microglobulin (beta 2m-/-), I-A (class II-/-), or CD4 (CD4-/-) genes were examined for their capacity to resolve Chlamydia trachomatis genital tract infection. C57BL/6 and beta 2m-/- mice resolved infection similarly and were culture negative by 4 to 5 weeks following infection. Conversely, ...

journal_title：Infection and immunity

authors： Morrison RP,Feilzer K,Tumas DB

更新日期：1995-12-01 00:00:00

abstract：:We previously demonstrated the suppression of cell-mediated immunity to Listeria monocytogenes by Pseudomonas aeruginosa-induced, macrophage-like cells. The present study was undertaken to evaluate the mechanism for this suppression. P. aeruginosa supernatant was shown to activate macrophages by the criteria of increa...

journal_title：Infection and immunity

authors： Petit JC,Richard G,Burghoffer B,Daguet GL

更新日期：1985-08-01 00:00:00

abstract：:The antigenic relationship of glucosyltransferases (GTF) produced by different serotypes of Streptococcus mutans was studied by using a functional inhibition assay. Rat, rabbit, or hamster immune fluids, directed to cell-associated or supernatant-derived GTF, were tested against ammonium sulfate-precipitated culture s...

journal_title：Infection and immunity

authors： Smith DJ,Taubman MA

更新日期：1977-01-01 00:00:00

abstract：:Continuous virus production is a characteristic of chicken embryo fibroblasts (CEF) infected and transformed by a nondefective Schmidt-Ruppin subgroup A Rous sarcoma virus. This virus production has been examined with particular attention to the amount of newly budded virus which remained cell-associated, and to the a...

journal_title：Infection and immunity

authors： Volkmann KR,Morgan HR

更新日期：1974-10-01 00:00:00

abstract：:Brucellosis is a bacterial disease of animals and humans. Brucella abortus barely activates the innate immune system at the onset of infection, and this bacterium is resistant to the microbicidal action of complement. Since complement stands as the first line of defense during bacterial invasions, we explored the role...

journal_title：Infection and immunity

authors： González-Espinoza G,Barquero-Calvo E,Lizano-González E,Alfaro-Alarcón A,Arias-Gómez B,Chaves-Olarte E,Lomonte B,Moreno E,Chacón-Díaz C

更新日期：2018-09-21 00:00:00

abstract：:Urinary tract infection (UTI) is the second most common infection in humans, making it a global health priority. Nearly half of all women will experience a symptomatic UTI, with uropathogenic Escherichia coli (UPEC) being the major causative agent of the infection. Although there has been extensive research on UPEC vi...

journal_title：Infection and immunity

authors： Sintsova A,Smith S,Subashchandrabose S,Mobley HL

更新日期：2018-02-20 00:00:00

abstract：:Intestinal epithelial cells (IECs), including secretory goblet cells, form essential physiochemical barriers that separate luminal bacteria from underlying immune cells in the intestinal mucosa. IECs are common targets for enteric bacterial pathogens, with hosts responding to these microbes through innate toll-like re...

journal_title：Infection and immunity

authors： Bhinder G,Stahl M,Sham HP,Crowley SM,Morampudi V,Dalwadi U,Ma C,Jacobson K,Vallance BA

更新日期：2014-09-01 00:00:00

abstract：:In the mouse model of Lyme borreliosis, the host immune response during infection with Borrelia burgdorferi results in the remission of carditis and arthritis, as well as global reduction of spirochete numbers in tissues, without elimination of infection. These events were recapitulated by passive transfer of immune s...

journal_title：Infection and immunity

authors： Barthold SW,Hodzic E,Tunev S,Feng S

更新日期：2006-08-01 00:00:00

abstract：:Citrobacter rodentium, a murine model pathogen for enteropathogenic Escherichia coli, colonizes the surface of intestinal epithelial cells and causes mucosal inflammation. This bacterium is an ideal model for investigating pathogen-host immune interactions in the gut. It is well known that gene transcripts for Th1 cyt...

journal_title：Infection and immunity

authors： Shiomi H,Masuda A,Nishiumi S,Nishida M,Takagawa T,Shiomi Y,Kutsumi H,Blumberg RS,Azuma T,Yoshida M

更新日期：2010-06-01 00:00:00

abstract：:Antibodies induced in sera and saliva of rats and rabbits immunized with ribosomal preparations from Streptococcus mutans 6715 inhibited transport of glucose by the phosphotransferase system by greater than 60%, acid production from sucrose by greater than 95%, and growth of the homologous S. mutans by greater than 59...

journal_title：Infection and immunity

authors： Gregory RL,Michalek SM,Shechmeister IL,McGhee JR

更新日期：1984-07-01 00:00:00

abstract：:The tetrasaccharide 3-deoxy-alpha-D-manno-2-octulosonic acid (alpha-KDO) (2----8)-alpha-KDO(2----4)-alpha-KDO(2----6)-beta GlcNAc, a partial structure of chlamydial lipopolysaccharide (LPS) representing a genus-specific epitope, was synthesized and covalently linked to bovine serum albumin, resulting in an artificial ...

journal_title：Infection and immunity

authors： Fu Y,Baumann M,Kosma P,Brade L,Brade H

更新日期：1992-04-01 00:00:00

abstract：:Susceptibility to the lethal toxicity of endotoxin in mice pretreated with emulsified trehalose-6,6'-dimycolate was enhanced by (i) increasing the oil concentration while keeping the Tween concentration constant; and (ii) decreasing the Tween concentration, while keeping the oil concentration constant. ...

journal_title：Infection and immunity

authors： Yarkoni E,Rapp HJ

更新日期：1979-05-01 00:00:00

abstract：:Culture fluids after growth of Mycobacterium bovis BCG on Sauton medium contain actively secreted proteins and proteins released by bacterial lysis. BCG culture fluids and sonicates of Mycobacterium tuberculosis and Mycobacterium paratuberculosis were tested after separation by gel filtration and sodium dodecyl sulfat...

journal_title：Infection and immunity

authors： Harboe M,Wiker HG,Ulvund G,Lund-Pedersen B,Andersen AB,Hewinson RG,Nagai S

更新日期：1998-01-01 00:00:00

abstract：:The obligate intracellular parasite Toxoplasma gondii critically relies on host cell invasion during infection. Proteins secreted from the apical micronemes are central components for host cell recognition, invasion, egress, and virulence. Although previous work established that the sporozoite protein with an altered ...

journal_title：Infection and immunity

authors： Huynh MH,Boulanger MJ,Carruthers VB

更新日期：2014-10-01 00:00:00

abstract：:Chemiluminescence of human alveolar macrophages (AM) was evaluated in vitro. Unstimulated AM generated chemiluminescence that remained constant during incubation. Addition of heat-killed Staphylococcus aureus 502A (HKB) or a chemical agent, phorbol myristate acetate, produced high rates of chemiluminescence that were ...

journal_title：Infection and immunity

authors： Beall GD,Repine JE,Hoidal JR,Rasp FL

更新日期：1977-07-01 00:00:00

abstract：:The antiphagocytic effect of the Staphylococcus aureus capsule is known to be related to its ability to interfere with opsonization by normal human serum. In this study, evidence is presented with isolated cell surface components which indicates that the capsule hinders opsonization by masking cell wall peptidoglycan....

journal_title：Infection and immunity

authors： Wilkinson BJ,Peterson PK,Quie PG

更新日期：1979-02-01 00:00:00

abstract：:Spleen cells from BALB/c mice infected with 2 X 10(7) L. major promastigotes and developing progressive disease produced significantly lower levels of interleukin-2 (IL-2) in response to concanavalin A stimulation than did spleen cells from uninfected mice. In contrast, spleen cells from sublethally irradiated and inf...

journal_title：Infection and immunity

authors： Cillari E,Liew FY,Lelchuk R

更新日期：1986-11-01 00:00:00

abstract：:Gastroesophageal reflux (GER) frequently occurs in patients with respiratory disease and is particularly prevalent in patients with cystic fibrosis. GER is a condition in which the duodenogastric contents of the stomach leak into the esophagus, in many cases resulting in aspiration into the respiratory tract. As such,...

journal_title：Infection and immunity

authors： Legendre C,Reen FJ,Woods DF,Mooij MJ,Adams C,O'Gara F

更新日期：2014-09-01 00:00:00

abstract：:Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that other mechanisms of vir...

journal_title：Infection and immunity

authors： McClelland EE,Perrine WT,Potts WK,Casadevall A

更新日期：2005-10-01 00:00:00

abstract：:Patients with chronic bronchitis are colonized by and may develop acute bronchopulmonary infection due to nontypable Haemophilus influenzae (NTHI) despite the presence of bactericidal and opsonizing antibody to the infecting organism. To test the hypothesis that secretory immunoglobulin A (IgA) interferes with host de...

journal_title：Infection and immunity

authors： Musher DM,Goree A,Baughn RE,Birdsall HH

更新日期：1984-07-01 00:00:00

abstract：:Escherichia coli 536 (O6:K15:H31), which was isolated from a case of urinary tract infection, determines high nephropathogenicity in a rat pyelonephritis system as measured by renal bacterial counts 7 days after infection. The loss of S fimbrial adhesin formation (Sfa-) (mannose-resistant hemagglutination [Mrh-] and f...

journal_title：Infection and immunity

authors： Marre R,Hacker J,Henkel W,Goebel W

更新日期：1986-12-01 00:00:00

abstract：:Brucella abortus is recognized by several Toll-like receptor (TLR)-associated pathways triggering proinflammatory responses that affect both the nature and intensity of the immune response. Previously, we demonstrated that B. abortus-mediated dendritic cell (DC) maturation and control of infection are dependent on the...

journal_title：Infection and immunity

authors： de Almeida LA,Macedo GC,Marinho FA,Gomes MT,Corsetti PP,Silva AM,Cassataro J,Giambartolomei GH,Oliveira SC

更新日期：2013-05-01 00:00:00

abstract：:In the presence of temporary obstruction (20 h), ascending Escherichia coli urinary infection leads to irreversible acute exudative pyelonephritis (AEP) in rats. The purpose of the present study was to investigate the early inflammatory events which take place in response to the presence of bacteria in the kidney pare...

journal_title：Infection and immunity

authors： Glauser MP,Francioli PB,Bille J,Bonard M,Meylan P

更新日期：1983-05-01 00:00:00

abstract：:Vibrio cholerae O1 has two biotypes, El Tor and Classical, and the latter is now presumed to be extinct in nature. Under carbohydrate-rich growth conditions, El Tor biotype strains produce the neutral fermentation end product 2,3-butanediol (2,3-BD), which prevents accumulation of organic acids from mixed acid ferment...

journal_title：Infection and immunity

authors： Bari W,Song YJ,Yoon SS

更新日期：2011-08-01 00:00:00