Anti-Pneumococcal Capsular Polysaccharide Antibody Response and CD5 B Lymphocyte Subsets.

abstract：:Pseudomonas aeruginosa, an important opportunistic pathogen of humans, exploits epithelial damage to establish infection. We have rigorously explored the role of N-glycoproteins and heparan sulfate proteoglycans (HSPGs) in P. aeruginosa-mediated attachment and subsequent downstream events at the apical (AP) and basola...

journal_title：Infection and immunity

authors： Bucior I,Mostov K,Engel JN

更新日期：2010-03-01 00:00:00

abstract：:Acquired cellular immunity to infection with Mycobacterium tuberculosis is believed to reside in the capacity of mononuclear phagocytes of immunized animals to inhibit intracellular multiplication of the parasite. However, in macrophage tissue culture systems, it has been customary to employ streptomycin in the medium...

journal_title：Infection and immunity

authors： Patterson RJ,Youmans GP

更新日期：1970-01-01 00:00:00

abstract：:Adhesion of Trichomonas vaginalis is believed to be dependent on four adhesion proteins, which are thought to bind to vaginal epithelial cells in a specific manner with a ligand-receptor type of interaction. However, the specific receptors on the host cell have not yet been identified. In this work, the ability of the...

journal_title：Infection and immunity

authors： Addis MF,Rappelli P,Fiori PL

更新日期：2000-07-01 00:00:00

abstract：:Vitamin D(3) (1,25-dihydroxycholecalciferol) induced the phagocyte oxidative burst and intracellular killing of Salmonella enterica serovar Typhimurium in a phosphatidylinositol 3-kinase-dependent manner. The antimicrobial effect was more pronounced for Salmonella SodCI and SodCII mutants, confirming the role of the p...

journal_title：Infection and immunity

authors： Sly LM,Guiney DG,Reiner NE

更新日期：2002-09-01 00:00:00

abstract：:Macrophages are critical mediators of innate immunity and must be overcome for bacterial pathogens to cause disease. The Gram-positive bacterium Staphylococcus aureus produces virulence factors that impede macrophages and other immune cells. We previously determined that production of the metabolic cofactor lipoic aci...

journal_title：Infection and immunity

authors： Grayczyk JP,Alonzo F 3rd

更新日期：2019-09-19 00:00:00

abstract：:Immune responses of mice to Streptococcus mutans serotype c were analyzed by means of the enzyme-linked immunospot assay to determine the predominant specificities of the antibodies developed. In general, the numbers of splenic antibody-secreting cells correlated with serum antibody levels. A low dose (10(8) CFU) of k...

journal_title：Infection and immunity

authors： Russell MW,Czerkinsky C,Moldoveanu Z

更新日期：1986-08-01 00:00:00

abstract：:The antigenic relationship of six different strains of Paracoccidioides brasiliensis was investigated by the agar-gel immunodiffusion test. Soluble antigens prepared from the two morphological phases of the fungus were diffused against human sera obtained from eight patients with paracoccidioidomycosis (South American...

journal_title：Infection and immunity

authors： Restrepo-Moreno A

更新日期：1970-09-01 00:00:00

abstract：:We determined the diphtheria toxin phenotype of specially selected isolates of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis (C. ovis). All produced proteins similar in size and immunological structure to diphtheria toxin. As with diphtheria toxin, they exhibited ADP-ribosylating activity, and their ...

journal_title：Infection and immunity

authors： Wong TP,Groman N

更新日期：1984-03-01 00:00:00

abstract：:Campylobacter rectus is a putative periodontopathogen which expresses a proteinaceous surface layer (S-layer) external to the outer membrane. S-layers are considered to play a protective role for the microorganism in hostile environments. The S-layer proteins from six different C. rectus strains (five human isolates a...

journal_title：Infection and immunity

authors： Nitta H,Holt SC,Ebersole JL

更新日期：1997-02-01 00:00:00

abstract：:Newly hatched chicks were vaccinated orally with a genetically defined Salmonella enteritidis aroA candidate, strain CVL30. In chickens immunized with 10(5) or 10(9) CFU and challenged by the intravenous route with 10(8) CFU of S. enteritidis 109 Nalr at 8 weeks old, there were similar reductions in colonization of th...

journal_title：Infection and immunity

authors： Cooper GL,Venables LM,Woodward MJ,Hormaeche CE

更新日期：1994-11-01 00:00:00

abstract：:Treatment of Rickettsia prowazekii-infected L929 cells with gamma interferon (IFN-gamma) immediately after infection altered the lipid metabolism of the host cells as determined by measurement of phospholipid hydrolysis and oleic acid incorporation into phospholipids and neutral lipids. At 48 h postinfection, there wa...

journal_title：Infection and immunity

authors： Winkler HH,Day L,Daugherty R,Turco J

更新日期：1993-08-01 00:00:00

abstract：:Adoptive immunity is poorly expressed in normal syngeneic mice. This phenomenon was studied by using experimental antituberculosis immunity as a model system representing pure cell-mediated immunity. Expression of adoptive immunity was facilitated by pretreating recipients with sublethal ionizing radiation (500 rads) ...

journal_title：Infection and immunity

authors： Lefford MJ

更新日期：1983-07-01 00:00:00

abstract：:Targeting an antigen to Fc receptors (FcR) can enhance the immune response to the antigen in the absence of adjuvant. Furthermore, we recently demonstrated that intranasal immunization with an FcγR-targeted antigen enhances protection against a category A intracellular mucosal pathogen, Francisella tularensis. To dete...

journal_title：Infection and immunity

authors： Bitsaktsis C,Iglesias BV,Li Y,Colino J,Snapper CM,Hollingshead SK,Pham G,Gosselin DR,Gosselin EJ

更新日期：2012-03-01 00:00:00

abstract：:Apical membrane antigen 1 (AMA-1) is an invasion-related Plasmodium antigen that is expressed during both intracellular and extracellular asexual stages of the parasite's life cycle, making it an ideal target for induction of humoral and cellular immune responses that can protect against malaria. We show here that whe...

journal_title：Infection and immunity

authors： Bouillet LÉ,Dias MO,Dorigo NA,Moura AD,Russell B,Nosten F,Renia L,Braga EM,Gazzinelli RT,Rodrigues MM,Soares IS,Bruna-Romero O

更新日期：2011-09-01 00:00:00

abstract：:Minor salivary glands of the oral mucosa in healthy monkeys (Macaca fascicularis and Macaca mulatta) contain organized structural units suitable for recognizing and processing antigens. A previous study of M. fascicularis monkeys provided experimental evidence of retrograde access of oral antigens deep into the minor ...

journal_title：Infection and immunity

authors： Nair PN,Schroeder HE

更新日期：1983-07-01 00:00:00

abstract：:Immunization of monkeys with the 82-kDa rhoptry protein (p82) of Plasmodium falciparum can protect them against a lethal blood stage challenge, and monoclonal antibodies to p82 inhibit parasite growth in vitro. The role that a p82-specific immune response might play in human immunity to the parasite is not known. To d...

journal_title：Infection and immunity

authors： Howard RF,Jensen JB,Franklin HL

更新日期：1993-07-01 00:00:00

abstract：:Specific proteolytic destruction of the human chemotaxin, C5a, is a property of group A and B streptococcal pathogens. Here we show that virulent group G streptococci from human sources also express C5a peptidase activity. The enzyme responsible for this activity is approximately the same size as and is antigenically ...

journal_title：Infection and immunity

authors： Cleary PP,Peterson J,Chen C,Nelson C

更新日期：1991-07-01 00:00:00

abstract：:In vivo administration of Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) to mice induced apoptosis before a specific immune response. Apoptosis was associated with the expression of immunoglobulin and Ia on B cells and of CD5 and several markers on T cells. Apoptosis peaked in the spleen and lymph nodes on day 2...

journal_title：Infection and immunity

authors： Isogai E,Isogal H,Kimura K,Fujii N,Takagi S,Hirose K,Hayashi M

更新日期：1996-04-01 00:00:00

abstract：:Helicobacter pylori infection is thought to be involved in the development of several gastric diseases. Two H. pylori virulence factors (vacuolating cytotoxin A and cytotoxin-associated gene A) reportedly interact with lipid rafts in gastric epithelial cells. The role of Toll-like receptor (TLR)-mediated signaling in ...

journal_title：Infection and immunity

authors： Lu DY,Chen HC,Yang MS,Hsu YM,Lin HJ,Tang CH,Lee CH,Lai CK,Lin CJ,Shyu WC,Lin FY,Lai CH

更新日期：2012-05-01 00:00:00

abstract：:To analyze the role of interleukin-10 (IL-10) in bacterial cerebral infections, we studied cerebral listeriosis in IL-10-deficient (IL-10(-/-)) and wild-type (WT) mice, the latter of which express high levels of IL-10 in both primary and secondary cerebral listeriosis. IL-10(-/-) mice succumbed to primary as well as s...

journal_title：Infection and immunity

authors： Deckert M,Soltek S,Geginat G,Lütjen S,Montesinos-Rongen M,Hof H,Schlüter D

更新日期：2001-07-01 00:00:00

abstract：:This longitudinal prospective study shows that antibodies to the N-terminal block 2 region of the Plasmodium falciparum merozoite surface protein 1 (MSP-1) are associated with protection against clinical malaria in an area of stable but seasonal malaria transmission of Ghana. Antibodies to the block 2 region of MSP-1 ...

journal_title：Infection and immunity

authors： Cavanagh DR,Dodoo D,Hviid L,Kurtzhals JA,Theander TG,Akanmori BD,Polley S,Conway DJ,Koram K,McBride JS

更新日期：2004-11-01 00:00:00

abstract：:A soluble hemagglutinin/protease produced by Vibrio cholerae, which has previously been shown to hydrolyze fibronectin and ovomucin and to cleave lactoferrin and the A subunit of the heat-labile enterotoxin of Escherichia coli, appears to be a zinc metalloendopeptidase. Both its hemagglutinative and protease functions...

journal_title：Infection and immunity

authors： Booth BA,Boesman-Finkelstein M,Finkelstein RA

更新日期：1983-11-01 00:00:00

abstract：:Yersinia enterocolitica is a human pathogen that is ubiquitous in livestock, especially pigs. The bacteria are able to colonize the intestinal tract of a variety of mammalian hosts, but the severity of induced gut-associated diseases (yersiniosis) differs significantly between hosts. To gain more information about the...

journal_title：Infection and immunity

authors： Schaake J,Kronshage M,Uliczka F,Rohde M,Knuuti T,Strauch E,Fruth A,Wos-Oxley M,Dersch P

更新日期：2013-11-01 00:00:00

abstract：:Actinlike material was obtained from disrupted Pseudomonas aeruginosa cells by a modification of the method of Hancock and Nikaido (J. Bacteriol. 136:381-390) for isolating outer membrane vesicles. Pelleted membranes were dissolved in Laemmli sample buffer and electrophoresed in parallel lanes with purified rabbit ske...

journal_title：Infection and immunity

authors： Berk RS,Moon M,Higbee R,Cramer C,Roher A,Weis M,Hazlett L

更新日期：1985-11-01 00:00:00

abstract：:Group A streptococci of M protein type 5 have been epidemiologically related to acute rheumatic fever in a number of reported outbreaks. Preliminary bacteriological evidence suggests that M5 may be an important "rheumatogenic" type in Santiago, Chile. To assess further the relationship of this streptococcal serotype t...

journal_title：Infection and immunity

authors： Bisno AL,Berrios X,Quesney F,Monroe DM Jr,Dale JB,Beachey EH

更新日期：1982-11-01 00:00:00

abstract：:Salmonella enterica serovar Pullorum is worldwide a poultry pathogen of considerable economic importance, particularly in those countries with a developing poultry industry. In addition to the characteristic high mortality rates among young chicks, one of the features of Salmonella serovar Pullorum infection is that i...

journal_title：Infection and immunity

authors： Wigley P,Berchieri A Jr,Page KL,Smith AL,Barrow PA

更新日期：2001-12-01 00:00:00

abstract：:Both dextransucrase and mutansynthetase activities have been purified from the culture fluids of Streptococcus mutans GS-5 (serotype c). Although homogeneous dextransucrase preparations normally synthesize little insoluble glucan, essentially all of the glucan synthesized by this enzyme in the presence of 1.5 M (NH4)2...

journal_title：Infection and immunity

authors： Kuramitsu HK,Wondrack L

更新日期：1983-11-01 00:00:00

abstract：:The mechanisms of immunity to salmonellae conferred by immunization with live vaccines were studied by adoptive transfer using the mouse-virulent strain Salmonella typhimurium C5 and innately susceptible BALB/c (ltys) mice. This organism cannot establish a sublethal infection in naive BALB/c mice. Animals immunized 2 ...

journal_title：Infection and immunity

authors： Mastroeni P,Villarreal-Ramos B,Hormaeche CE

更新日期：1993-09-01 00:00:00

abstract：:The group R streptococcal group antigen has been shown to be a polysaccharide located at the surface of the cell wall of the organism. The antigen was extracted from cell walls in 0.05 n HCl or 5% trichloracetic acid at 100 C, from whole cells at room temperature in 0.85% NaCl or 0.1 m acetate (pH 5.0), and by sonic o...

journal_title：Infection and immunity

authors： Soprey P,Slade HD

更新日期：1972-01-01 00:00:00

abstract：:The ultrastructural appearance of the "halozone" formed at the interface between the spotted fever agent Rickettsia rickettsii and the cytoplasm of persistently infected cultured vole cells (Microtus pennsylvanicus) was studied by transmission electron microscopy. In sections of epoxy-embedded specimens stained with u...

journal_title：Infection and immunity

authors： Todd WJ,Burgdorfer W,Wray GP

更新日期：1983-09-01 00:00:00