Human and animal isolates of Yersinia enterocolitica show significant serotype-specific colonization and host-specific immune defense properties.

abstract：:Adherence to fibrinogen and fibronectin plays a crucial role in Staphylococcus aureus experimental endocarditis. Previous genetic studies have shown that infection and carriage isolates do not systematically differ in their virulence-related genes, including genes conferring adherence, such as clfA and fnbA. We set ou...

journal_title：Infection and immunity

authors： Ythier M,Entenza JM,Bille J,Vandenesch F,Bes M,Moreillon P,Sakwinska O

更新日期：2010-04-01 00:00:00

abstract：:A large-scale DNA vaccination trial was performed with sheep to investigate whether an antigen targeted by CTLA-4 enhanced and accelerated the humoral immune response. Vaccination with genetically detoxified phospholipase D (DeltaPLD) has been shown to be effective, at least partially, against Corynebacterium pseudotu...

journal_title：Infection and immunity

authors： Chaplin PJ,De Rose R,Boyle JS,McWaters P,Kelly J,Tennent JM,Lew AM,Scheerlinck JP

更新日期：1999-12-01 00:00:00

abstract：:Pro- and anti-inflammatory cytokines and their signaling pathways play key roles in protection from and pathogenesis of mycobacterial infection, and their balance and dynamic changes may control or predict clinical outcome. Peripheral blood cells' capacity to produce proinflammatory (tumor necrosis factor alpha [TNF-a...

journal_title：Infection and immunity

authors： Sahiratmadja E,Alisjahbana B,de Boer T,Adnan I,Maya A,Danusantoso H,Nelwan RH,Marzuki S,van der Meer JW,van Crevel R,van de Vosse E,Ottenhoff TH

更新日期：2007-02-01 00:00:00

abstract：:The objective of this research was to determine whether gram-negative bacteria frequently isolated from periodontally diseased sites contained polyclonal B-cell activators. Polyclonal B-cell activation, which results in nonspecific activation of multiple B-cell clones was analyzed by a hemolysis-in-gel assay designed ...

journal_title：Infection and immunity

authors： Bick PH,Carpenter AB,Holdeman LV,Miller GA,Ranney RR,Palcanis KG,Tew JG

更新日期：1981-10-01 00:00:00

abstract：:Analyses of chemical composition in whole cells of Rickettsia tsutsugamushi were performed and compared with those of the other rickettsiae and gram-negative bacteria. The results indicated that R. tsutsugamushi does not contain detectable amounts of 3-deoxy-D-mannooctulosonic acid, heptose, muramic acid, or glucosami...

journal_title：Infection and immunity

authors： Amano K,Tamura A,Ohashi N,Urakami H,Kaya S,Fukushi K

更新日期：1987-09-01 00:00:00

abstract：:Antiserum and purified immunoglobulin directed against Mycoplasma pneumoniae membrane protein P1 were examined for their influence on mycoplasma viability, metabolism, and cytadsorption. Anti-P1 immunoglobulin inhibited adherence of M. pneumoniae to hamster tracheal rings in vitro by up to 80% and inhibited hemadsorpt...

journal_title：Infection and immunity

authors： Krause DC,Baseman JB

更新日期：1983-03-01 00:00:00

abstract：:V beta 10(+) and V beta 14(+) T cells were selectively increased 7 to 14 days following infection in the lungs of naive mice infected with Histoplasma capsulatum. Following secondary challenge of immune mice, V beta 1(+) and V beta 8.1(+) cells were sporadically increased. Elimination of V beta 10(+) and V beta 14(+) ...

journal_title：Infection and immunity

authors： Deepe GS Jr,Gibbons RS,Ward SR

更新日期：2002-03-01 00:00:00

abstract：:Phagocytosis of Borrelia burgdorferi by human polymorphonuclear leukocytes triggers oxygen-dependent and -independent mechanisms of potentially cidal outcome. Nevertheless, no factor or process has yet been singled out as being borreliacidal. We have studied the B. burgdorferi-killing ability of the myeloperoxidase-H2...

journal_title：Infection and immunity

authors： Garcia R,Gusmani L,Murgia R,Guarnaccia C,Cinco M,Rottini G

更新日期：1998-04-01 00:00:00

abstract：:Pneumocystis carinii pneumonia (PcP) is a clinically important infection of immunocompromised patients. Although the interaction of Pneumocystis with the alveolar epithelium has been well documented, very little information regarding the epithelial response to Pneumocystis is currently available. In order to study Pne...

journal_title：Infection and immunity

authors： Wang J,Gigliotti F,Maggirwar S,Johnston C,Finkelstein JN,Wright TW

更新日期：2005-05-01 00:00:00

abstract：:We previously identified a cell wall-associated protein from Fusobacterium nucleatum, a Gram-negative bacterium of the oral cavity, that induces human beta defensin 2 (hBD-2) in primary human oral epithelial cells (HOECs) and designated it FAD-I (Fusobacterium-associated defensin inducer). Here, we report differential...

journal_title：Infection and immunity

authors： Bhattacharyya S,Ghosh SK,Shokeen B,Eapan B,Lux R,Kiselar J,Nithianantham S,Young A,Pandiyan P,McCormick TS,Weinberg A

更新日期：2016-04-22 00:00:00

abstract：:Previous examination of thin sections of L929 cells heavily infected with the Q fever Priscilla isolate by conventional transmission electron microscopy indicated that the rickettsiae resided within multiple vacuoles. The present study using high-voltage electron microscopy and three-dimensional reconstruction reveale...

journal_title：Infection and immunity

authors： Hechemy KE,McKee M,Marko M,Samsonoff WA,Roman M,Baca O

更新日期：1993-10-01 00:00:00

abstract：:Vibrio cholerae is the causal organism of the diarrheal disease cholera. The rugose variant of V. cholerae is associated with the secretion of an exopolysaccharide. The rugose polysaccharide has been shown to confer increased resistance to a variety of agents, such as chlorine, bioacids, and oxidative and osmotic stre...

journal_title：Infection and immunity

authors： Ali A,Johnson JA,Franco AA,Metzger DJ,Connell TD,Morris JG Jr,Sozhamannan S

更新日期：2000-04-01 00:00:00

abstract：:Mice were infected with 170 Trichinella spiralis larvae, and their blood clearance of carbon particles was studied 4, 7, 13, 32, and 135 days later and compared with that of noninfected control mice. Clearance in mice with a 4-day-old infection was comparable to that in the controls; clearances in mice with 7- and 13-...

journal_title：Infection and immunity

authors： Barriga OO

更新日期：1980-12-01 00:00:00

abstract：:Newly hatched chicks were vaccinated orally with a genetically defined Salmonella enteritidis aroA candidate, strain CVL30. In chickens immunized with 10(5) or 10(9) CFU and challenged by the intravenous route with 10(8) CFU of S. enteritidis 109 Nalr at 8 weeks old, there were similar reductions in colonization of th...

journal_title：Infection and immunity

authors： Cooper GL,Venables LM,Woodward MJ,Hormaeche CE

更新日期：1994-11-01 00:00:00

abstract：:We characterized outer membrane proteins (OMPs) from selected Campylobacter jejuni, C. coli, and C. fetus strains by two-dimensional gel electrophoresis (2DGE), using isoelectric focusing and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and by immunoblotting with immune rabbit serum. The flage...

journal_title：Infection and immunity

authors： Dunn BE,Blaser MJ,Snyder EL

更新日期：1987-07-01 00:00:00

abstract：:Neuronal dysfunction can occur in the course of sepsis without meningitis. Sepsis-associated neuronal damage (SAND) was observed in the hippocampus within hours in experimental pneumococcal bacteremia. Intravascular challenge with purified bacterial cell wall recapitulated SAND. SAND persisted in PAFr(-/-) mice but wa...

journal_title：Infection and immunity

authors： Orihuela CJ,Fillon S,Smith-Sielicki SH,El Kasmi KC,Gao G,Soulis K,Patil A,Murray PJ,Tuomanen EI

更新日期：2006-07-01 00:00:00

abstract：:Fimbrial adhesins that mediate attachment to host cells are produced by most virulent Escherichia coli isolates. These virulence factors play an important role in the initial stages of bacterial colonization and also in determination of the host and tissue specificity. Isolates belonging to serotype O78 are known to c...

journal_title：Infection and immunity

authors： Babai R,Stern BE,Hacker J,Ron EZ

更新日期：2000-10-01 00:00:00

abstract：:Livers of normal mice trapped over 80% of intravenously injected 51Cr-labeled lipopolysaccharide after 1 h. Liver fractionation studies showed that nearly 45% of the labeled endotoxin was associated with cell nuclei, 20% with the mitochondrial-lysosomal fraction, and approximately 30% with the cell sap. Analysis of th...

journal_title：Infection and immunity

authors： Zlydaszyk JC,Moon RJ

更新日期：1976-07-01 00:00:00

abstract：:To develop targeted gene integration in the periodontal pathogen Actinobacillus actinomycetemcomitans, a ColE1-based, spectinomycin-resistant plasmid containing a segment of the leukotoxin gene was electroporated into strain JP2. In all of the stable spectinomycin-resistant transformants that arose, the plasmid had re...

journal_title：Infection and immunity

authors： Kolodrubetz D,Phillips LH,Ezzo PJ,Kraig E

更新日期：1995-07-01 00:00:00

abstract：:Cytokine gene expression in cells migrating in afferent and efferent intestinal lymph was monitored for extended time periods in individual sheep experimentally infected with the nematode Trichostrongylus colubriformis. Animals from stable selection lines with increased levels of either genetic resistance (R) or susce...

journal_title：Infection and immunity

authors： Pernthaner A,Cole SA,Morrison L,Hein WR

更新日期：2005-04-01 00:00:00

abstract：:Human gamma delta T cells are known to respond at high frequencies to pathogenic mycobacteria. Here we show that opportunistic strains of mycobacteria share with pathogenic mycobacteria the ability to trigger at high frequencies human V gamma 9V delta 2 T-cell-receptor-positive T lymphocytes. Stimulating ligands were ...

journal_title：Infection and immunity

authors： Häcker G,Kromer S,Heeg K,Ivanyi J,Wagner H,Pfeffer K

更新日期：1992-07-01 00:00:00

abstract：:Salivary proline-rich proteins (PRPs), which were purified from parotid saliva, were adsorbed onto 15-nm-diameter gold particles to visualize specific binding of the salivary molecules to Actinomyces viscosus type 1 fimbriae. Negatively stained preparations incubated with PRP-gold conjugates but not bovine serum album...

journal_title：Infection and immunity

authors： Leung KP,Nesbitt WE,Fischlschweiger W,Hay DI,Clark WB

更新日期：1990-06-01 00:00:00

abstract：:Moraxella (Branhamella) catarrhalis is an important bacterial cause of otitis media in children and lower respiratory tract infections in adults. In this study, we describe the presence of a novel high-molecular-weight outer membrane protein (HMW-OMP). This protein varies from 350 to 720 kDa in apparent molecular mass...

journal_title：Infection and immunity

authors： Klingman KL,Murphy TF

更新日期：1994-04-01 00:00:00

abstract：:Each of the four epidermal growth factor (EGF)-like domains of the Plasmodium falciparum sexual-stage antigen Pfs25 has been individually expressed as a yeast-secreted recombinant protein (yEGF1 through yEGF4). All four are recognized by the immune sera of animals and humans vaccinated with TBV25H (the corresponding y...

journal_title：Infection and immunity

authors： Stowers AW,Keister DB,Muratova O,Kaslow DC

更新日期：2000-10-01 00:00:00

abstract：:The NikR protein is a nickel-dependent regulatory protein which is a member of the ribbon-helix-helix family of transcriptional regulators. The gastric pathogen Helicobacter pylori expresses a NikR ortholog, which was previously shown to mediate regulation of metal metabolism and urease expression, but the mechanism g...

journal_title：Infection and immunity

authors： Ernst FD,Kuipers EJ,Heijens A,Sarwari R,Stoof J,Penn CW,Kusters JG,van Vliet AH

更新日期：2005-11-01 00:00:00

abstract：:Science has a critical role to play in addressing humanity's most important challenges in the twenty-first century. However, the contemporary scientific enterprise has developed in ways that prevent it from reaching maximum effectiveness and detract from the appeal of a research career. To be effective, the methodolog...

journal_title：Infection and immunity

authors： Fang FC,Casadevall A

更新日期：2012-03-01 00:00:00

abstract：:Ocular inflammation is one of the consequences of infection with the protozoan parasite Toxoplasma gondii. Even if lesions are self-healing in immunocompetent persons, they pose a lifetime risk of reactivation and are a serious threat to vision. As there are virtually no immunological data on reactivating ocular toxop...

journal_title：Infection and immunity

authors： Rochet É,Brunet J,Sabou M,Marcellin L,Bourcier T,Candolfi E,Pfaff AW

更新日期：2015-05-01 00:00:00

abstract：:The pattern of invasion of human hair in vitro by the dermatophyte Microsporum gypseum was studied by transmission and scanning electron microscopy. Mycelia that invaded the hair cortex through the edge of cuticles showed a flattened "frond" growth in contrast to the filamentous form seen on ordinary laboratory media....

journal_title：Infection and immunity

authors： Kanbe T,Tanaka K

更新日期：1982-11-01 00:00:00

abstract：:The immunoprophylactic effect of chemically inactivated Pseudomonas aeruginosa exotoxin A in experimental pseudomonas infections was studied. Exotoxin A toxoids were prepared by Formalin (f-TXD) or glutaraldehyde (g-TXD) treatment. Immunization of mice with three or four doses (10 micrograms each) of f-TXD and the syn...

journal_title：Infection and immunity

authors： Pavlovskis OR,Edman DC,Leppla SH,Wretlind B,Lewis LR,Martin KE

更新日期：1981-05-01 00:00:00

abstract：:The development of vaccines for prevention of diseases caused by pathogenic species can encounter major obstacles if high sequence diversity is observed between individual strains. Therefore, development might be restricted either to conserved antigens, which are often rare, or to multivalent vaccines, which renders t...

journal_title：Infection and immunity

authors： Nayak A,Schüler W,Seidel S,Gomez I,Meinke A,Comstedt P,Lundberg U

更新日期：2020-03-23 00:00:00