The nickel-responsive regulator NikR controls activation and repression of gene transcription in Helicobacter pylori.

abstract：:Protective immunity against Toxoplasma gondii is known to be mediated mainly by T lymphocytes and gamma interferon (IFN-gamma). The contribution of CD4(+) and CD8(+) T-lymphocyte subsets to protective immune responses against T. gondii infection, triggered by a GRA1 (p24) DNA vaccine, was assessed in this study. In vi...

journal_title：Infection and immunity

authors： Scorza T,D'Souza S,Laloup M,Dewit J,De Braekeleer J,Verschueren H,Vercammen M,Huygen K,Jongert E

更新日期：2003-01-01 00:00:00

abstract：:Human immunodeficiency virus (HIV)-infected individuals are predisposed to recurrent oral candidiasis, and, although it has been assumed that this is because of deficient mucosal immune responses, this has not been properly established. The present study aimed to compare the concentrations and secretion rates of immun...

journal_title：Infection and immunity

authors： Coogan MM,Sweet SP,Challacombe SJ

更新日期：1994-03-01 00:00:00

abstract：:The importance of intact host defense mechanisms for successful antimicrobial therapy was investigated in an animal model. Recovery from lobar pneumococcal pneumonia as a result of penicillin therapy was studied in normal rats and in rats treated with cobra venom factor. This factor was used to selectively suppress th...

journal_title：Infection and immunity

authors： Bakker-Woudenberg IA,de Jong-Hoenderop JY,Michel MF

更新日期：1979-07-01 00:00:00

abstract：:In previous work, we identified xanthine oxidase (XO) as an important enzyme in the interaction between the host and enteropathogenic Escherichia coli(EPEC) and Shiga-toxigenic E. coli(STEC). Many of the biological effects of XO were due to the hydrogen peroxide produced by the enzyme. We wondered, however, if uric ac...

journal_title：Infection and immunity

authors： Crane JK,Broome JE,Lis A

更新日期：2016-03-24 00:00:00

abstract：:Influenza A/Scotland/74 (H3N2) and A/Victoria/75 (H3N2) cold-adapted (ca) recombinant viruses, prepared by mating the A/Ann Arbor/6/60 (H2N2) ca donor virus and influenza A wild-type virus, were evaluated in adult seronegative volunteers (serum hemagglutination-inhibiting antibody titer,

journal_title：Infection and immunity

authors： Murphy BR,Holley HP Jr,Berquist EJ,Levine MM,Spring SB,Maassab HF,Kendal AP,Chanock RM

更新日期：1979-02-01 00:00:00

abstract：:Ecto-5'-nucleotidase (CD73) is expressed abundantly on the apical surface of intestinal epithelial cells (IECs) and functions as the terminal enzyme in the generation of extracellular adenosine. Previous work demonstrated that adenosine signaling in IECs results in a number of tissue-protective effects during inflamma...

journal_title：Infection and immunity

authors： Kao DJ,Saeedi BJ,Kitzenberg D,Burney KM,Dobrinskikh E,Battista KD,Vázquez-Torres A,Colgan SP,Kominsky DJ

更新日期：2017-09-20 00:00:00

abstract：:The present study was performed to determine whether Histoplasma capsulatum (yeast phase) is able to activate the alternative complement pathway. H. capsulatum yeasts were shown to consume C3 in C4-deficient guinea pig serum. Immunoelectrophoretic conversion of alternative pathway component factor B confirmed that C3 ...

journal_title：Infection and immunity

authors： Ratnoff WD,Pepple JM,Winkelstein JA

更新日期：1980-10-01 00:00:00

abstract：:Oophorectomized, estrogen-treated rats were immunized by the intravaginal or intranasal route with a mannoprotein extract (MP) or secreted aspartyl proteinases (Sap) of Candida albicans, with or without cholera toxin as a mucosal adjuvant. Both routes of immunization were equally effective in (i) inducing anti-MP and ...

journal_title：Infection and immunity

authors： De Bernardis F,Boccanera M,Adriani D,Girolamo A,Cassone A

更新日期：2002-05-01 00:00:00

abstract：:We previously showed that the Uganda Palo Alto line of Plasmodium falciparum propagated in Saimiri monkeys and the line maintained in culture in human erythrocytes for many years in our laboratory are genetically unrelated (T. Fandeur, S. Bonnefoy, and O. Mercereau-Puijalon, Mol. Biochem. Parasitol. 47:167, 1991). Whe...

journal_title：Infection and immunity

authors： Fandeur T,Gysin J,Mercereau-Puijalon O

更新日期：1992-04-01 00:00:00

abstract：:Adherence of blastoconidia to epidermal corneocytes is an early event in Candida colonization and infection of the skin. Pathogenic species adhere more avidly than nonpathogenic species, transform to hyphal growth, and invade the stratum corneum of the skin. Adherence was studied by scanning electron microscopy of exp...

journal_title：Infection and immunity

authors： Ray TL,Payne CD

更新日期：1988-08-01 00:00:00

abstract：:Streptococcal pyrogenic exotoxin B (SpeB), a conserved cysteine protease expressed by virtually all Streptococcus pyogenes strains, has recently been shown to be an important virulence factor (S. Lukomski, S. Sreevatsan, C. Amberg, W. Reichardt, M. Woischnik, A. Podbielski, and J. M. Musser, J. Clin. Invest. 99:2574-2...

journal_title：Infection and immunity

authors： Lukomski S,Burns EH Jr,Wyde PR,Podbielski A,Rurangirwa J,Moore-Poveda DK,Musser JM

更新日期：1998-02-01 00:00:00

abstract：:Chronic infections play a significant role in the morbidity and mortality of patients with chronic airflow limitation. By stimulating airway inflammation, persistent infection has the potential to cause airway fibrosis. However, in patient this condition is most typically found in lungs damaged by other factors, such ...

journal_title：Infection and immunity

authors： McIntosh JC,Simecka JW,Ross SE,Davis JK,Miller EJ,Cassell GH

更新日期：1992-07-01 00:00:00

abstract：:Cells in the Brucella spp. are intracellular pathogens that survive and replicate within host monocytes. Brucella maintains persistent infections in animals despite the production of high levels of anti-Brucella-specific antibodies. To determine the effect of antibody opsonization on the ability of Brucella to establi...

journal_title：Infection and immunity

authors： Bellaire BH,Roop RM 2nd,Cardelli JA

更新日期：2005-06-01 00:00:00

abstract：:Bordetella pertussis, a causative agent of whooping cough, expresses BrkA, which confers serum resistance, but the closely related human pathogen that also causes whooping cough, Bordetella parapertussis, does not. Interestingly, B. parapertussis, but not B. pertussis, produces an O antigen, a factor shown in other mo...

journal_title：Infection and immunity

authors： Goebel EM,Wolfe DN,Elder K,Stibitz S,Harvill ET

更新日期：2008-04-01 00:00:00

abstract：:A murine monoclonal antibody was raised against the B95-8 strain of Epstein-Barr virus (EBV), which was isolated from a case of mononucleosis after blood transfusion (Hoffman et al. Proc. Natl. Acad. Sci. U.S.A. 77:2979, 1980). We provide evidence that neutralization of immortalization by this monoclonal antibody is v...

journal_title：Infection and immunity

authors： Miller G,Heston L,Hoffman G

更新日期：1982-09-01 00:00:00

abstract：:Antibiotic-resistant Klebsiella pneumoniae isolates constitute a great clinical challenge. One important resistance mechanism in K. pneumoniae is the metallo-β-lactamases (MBLs), which require zinc for their function. Thus, zinc chelation could be a strategy to resensitize K. pneumoniae to β-lactams. However, the pote...

journal_title：Infection and immunity

authors： Karadottir H,Coorens M,Liu Z,Wang Y,Agerberth B,Giske CG,Bergman P

更新日期：2019-12-17 00:00:00

abstract：:Individual strains of Staphylococcus aureus have different capacities to become internalized by osteoblasts. Here we report that the levels of sigma(B) expressed by S. aureus correlate with the capacity of this bacterium to be internalized by osteoblasts. However, sigma(B) is not essential for internalization and does...

journal_title：Infection and immunity

authors： Nair SP,Bischoff M,Senn MM,Berger-Bächi B

更新日期：2003-07-01 00:00:00

abstract：:Enterotoxigenic Escherichia coli (ETEC) is a major cause of traveler's diarrhea as well as of endemic diarrhea and stunting in children in developing areas. However, a small-mammal model has been badly needed to better understand and assess mechanisms, vaccines, and interventions. We report a murine model of ETEC diar...

journal_title：Infection and immunity

authors： Bolick DT,Medeiros PHQS,Ledwaba SE,Lima AAM,Nataro JP,Barry EM,Guerrant RL

更新日期：2018-06-21 00:00:00

abstract：:The response to reinfection with Ethiopian Leishmania donovani was evaluated in genetically determined noncure (H-2d) B10.D2 mice that are able to resolve infection due to sublethal irradiation pretreatment after inoculation with a low parasite dose and in C57BL/10 mice that demonstrate the genetically determined cure...

journal_title：Infection and immunity

authors： Ulczak OM,Ghadirian E,Skamene E,Blackwell JM,Kongshavn PA

更新日期：1989-09-01 00:00:00

abstract：:We constructed hha derivatives from both a clinical uropathogenic Escherichia coli isolate (strain FVL4) and a wild E. coli strain causing bovine diarrhea (strain CCB21) and analyzed the effect of the hha allele on the expression of the different virulence factors exhibited by these strains. Expression of hemolysin an...

journal_title：Infection and immunity

authors： Mouriño M,Madrid C,Balsalobre C,Prenafeta A,Muñoa F,Blanco J,Blanco M,Blanco JE,Juarez A

更新日期：1996-07-01 00:00:00

abstract：:In Pseudomonas aeruginosa, the second messenger cyclic-di-GMP and Gac/Rsm signaling pathways are associated with the transition from acute to chronic infection. Therefore, identification of the molecular mechanisms that govern lifestyle choice in bacteria is very important. Here, we identified a novel cyclic-di-GMP mo...

journal_title：Infection and immunity

authors： Jiao H,Li F,Wang T,Yam JKH,Yang L,Liang H

更新日期：2021-01-19 00:00:00

abstract：:We have reported that P388D1 cell line murine macrophages stimulated with lipopolysaccharide (LPS) from Actinobacillus actinomycetemcomitans release interleukin-1 (IL-1) inhibitor. The IL-1 inhibitor was purified from conditioned media of P388D1 cells stimulated with A. actinomycetemcomitans LPS for 72 h to homogeneit...

journal_title：Infection and immunity

authors： Nishihara T,Ohsaki Y,Ueda N,Saito N,Mundy GR

更新日期：1994-02-01 00:00:00

abstract：:Lyme disease (LD), the most prevalent tick-borne illness in North America, is caused by Borrelia burgdorferi The long-term survival of B. burgdorferi spirochetes in the mammalian host is achieved though VlsE-mediated antigenic variation. It is mathematically predicted that a highly variable surface antigen prolongs ba...

journal_title：Infection and immunity

authors： Rogovskyy AS,Gillis DC,Ionov Y,Gerasimov E,Zelikovsky A

更新日期：2016-12-29 00:00:00

abstract：:Preliminary studies established methods for obtaining maximum yields of viable cells. Liquid shaken cultures of Histoplasma capsulatum provided a maximum of 4 x 10(8) to 5 x 10(8) cells/ml regardless of the inoculum size. Under optimum conditions, cells were viable (90 to 95%) for 168 to 240 hr. Generation times range...

journal_title：Infection and immunity

authors： Garcia JP,Howard DH

更新日期：1971-08-01 00:00:00

abstract：:The development of vaccines for prevention of diseases caused by pathogenic species can encounter major obstacles if high sequence diversity is observed between individual strains. Therefore, development might be restricted either to conserved antigens, which are often rare, or to multivalent vaccines, which renders t...

journal_title：Infection and immunity

authors： Nayak A,Schüler W,Seidel S,Gomez I,Meinke A,Comstedt P,Lundberg U

更新日期：2020-03-23 00:00:00

abstract：:We used inhibitors of receptor-mediated endocytosis to study the mechanisms of infectivity, especially the uptake mechanism, of Chlamydia trachomatis for cultured cells. The effect of methylamine and monodansylcadaverine on the different stages of the chlamydial growth cycle in McCoy cells was examined. There was a do...

journal_title：Infection and immunity

authors： Söderlund G,Kihlström E

更新日期：1983-05-01 00:00:00

abstract：:Legionella pneumophila is a gram-negative facultative intracellular parasite of macrophages. Although L. pneumophila is the causative agent of a severe pneumonia known as Legionnaires' disease, it is likely that most infections caused by this organism are cleared by the host innate immune system. It is predicted that ...

journal_title：Infection and immunity

authors： Archer KA,Roy CR

更新日期：2006-06-01 00:00:00

abstract：:Woodchuck sera were tested for antigens and antibodies with tests which detect human hepatitis virus antigens and antibodies. Data on 264 woodchuck sera are presented. ...

journal_title：Infection and immunity

authors： Millman I,Halbherr T,Simmons H

更新日期：1982-02-01 00:00:00

abstract：:Evidence that the bactericidal ability and the stimulated oxidative metabolism of leukocytes appear in parallel during fetal development of the Minnesota Miniature pig has been obtained by application of the techniques applied to studies of human cells. It was demonstrated that leukocytes from 87- to 90-day fetuses we...

journal_title：Infection and immunity

authors： Holmes B,Day N,Haseman J,Good RA

更新日期：1972-02-01 00:00:00

abstract：:We have determined the amounts of specific anti-class 1 outer membrane protein antibodies in sera from 25 patients during the course of systemic meningococcal disease, using purified class 1 protein as the sensitizing antigen in an enzyme-linked immunosorbent assay. The class 1 protein was obtained from a variant of s...

journal_title：Infection and immunity

authors： Guttormsen HK,Wetzler LM,Solberg CO

更新日期：1994-04-01 00:00:00