Deficiency of peptidoglycan and lipopolysaccharide components in Rickettsia tsutsugamushi.

abstract：:A differential-display PCR procedure identified the capsular assembly gene kpsD after Escherichia coli type 1 fimbrial binding to mannose-coated Sepharose beads. Limiting-dilution reverse-transcribed PCRs confirmed down-regulation of the kpsD gene, and Northern blot and lacZ fusion analyses showed down-regulation of t...

journal_title：Infection and immunity

authors： Schwan WR,Beck MT,Hultgren SJ,Pinkner J,Woolever NL,Larson T

更新日期：2005-02-01 00:00:00

abstract：:Legionella pneumophila is ingested by both human macrophages and amoebae, and it multiplies within similar endocytic compartments in both eukaryotic species. Inhibitors of eukaryotic protein synthesis, such as cycloheximide and emetine, had no effect on the uptake of L. pneumophila by macrophages but completely abolis...

journal_title：Infection and immunity

authors： abu Kwaik Y,Fields BS,Engleberg NC

更新日期：1994-05-01 00:00:00

abstract：:The cyst cell wall β-glucans of Pneumocystis have been shown to stimulate immune responses in lung epithelial cells, dendritic cells, and alveolar macrophages. Little is known about how the trophic life forms, which do not have a fungal cell wall, interact with these innate immune cells. Here, we report differences in...

journal_title：Infection and immunity

authors： Evans HM,Bryant GL 3rd,Garvy BA

更新日期：2016-11-01 00:00:00

abstract：:We have reported that P388D1 cell line murine macrophages stimulated with lipopolysaccharide (LPS) from Actinobacillus actinomycetemcomitans release interleukin-1 (IL-1) inhibitor. The IL-1 inhibitor was purified from conditioned media of P388D1 cells stimulated with A. actinomycetemcomitans LPS for 72 h to homogeneit...

journal_title：Infection and immunity

authors： Nishihara T,Ohsaki Y,Ueda N,Saito N,Mundy GR

更新日期：1994-02-01 00:00:00

abstract：:Neutralizing antibodies were raised in mice that had been inoculated repeatedly with moderate quantities of human leukocyte interferon highly purified by affinity chromatography on immobilized anti-interferon globulins. Interferon preparations of lesser purity sensitized the mice to subsequent inoculations of interfer...

journal_title：Infection and immunity

authors： Dalton BJ,Ogburn CA,Paucker K

更新日期：1978-02-01 00:00:00

abstract：:We report here the identification and characterization of two zinc uptake systems, ZurAM and ZinABC, in the intracellular pathogen Listeria monocytogenes. Transcription of both operons was zinc responsive and regulated by the zinc-sensing repressor Zur. Deletion of either zurAM or zinA had no detectable effect on grow...

journal_title：Infection and immunity

authors： Corbett D,Wang J,Schuler S,Lopez-Castejon G,Glenn S,Brough D,Andrew PW,Cavet JS,Roberts IS

更新日期：2012-01-01 00:00:00

abstract：:The immune response to the mycobacterial 65-kDa heat shock protein (hsp65) is considered an important event in the induction of adjuvant arthritis (AA) in rats; this induction probably occurs through a molecular mimicry mechanism involving cross-reactivity against the rat homolog hsp60. To analyze the role of mammalia...

journal_title：Infection and immunity

authors： López-Guerrero JA,López-Bote JP,Ortiz MA,Gupta RS,Páez E,Bernabeu C

更新日期：1993-10-01 00:00:00

abstract：:Antigen 2 (Ag2), a major immunoreactive component of Coccidioides immitis mycelium- and spherule-phase cell walls, was recently cloned in our laboratory and was shown to elicit T-cell responses in Coccidioides-immune mice. In this investigation, we evaluated recombinant Ag2 (rAg2) and PCR-generated Ag2 truncations for...

journal_title：Infection and immunity

authors： Zhu Y,Tryon V,Magee DM,Cox RA

更新日期：1997-08-01 00:00:00

abstract：:Ingestion of 14C-amino acid-labeled Chlamydia psittaci (6BC) by mouse fibroblasts (L cells) was inhibited when the host cells were incubated for 30 min at 37 degrees C in Earle salts containing 10 mug of crystalline trypsin per ml. Tryptic digestion also inhibited the ingestion of 1-mum polystrene latex beads. Trypsin...

journal_title：Infection and immunity

authors： Byrne GI

更新日期：1976-09-01 00:00:00

abstract：:The role of cysteine proteinases in adherence of Trichomonas vaginalis NYH 286 to HeLa and human vaginal epithelial cells was evaluated. Only pretreatment of trichomonads, but not epithelial cells, with N-alpha-p-tosyl-L-lysine chloromethyl ketone (TLCK), an inhibitor of trichomonad cysteine proteinases, greatly dimin...

journal_title：Infection and immunity

authors： Arroyo R,Alderete JF

更新日期：1989-10-01 00:00:00

abstract：:Invasive aspergillosis is a major threat for patients suffering from chronic granulomatous disease (CGD). Although Aspergillus fumigatus is the most commonly encountered Aspergillus species, the presence of A. nidulans appears to be disproportionately high in CGD patients. The purpose of this study was to investigate ...

journal_title：Infection and immunity

authors： Henriet SS,Hermans PW,Verweij PE,Simonetti E,Holland SM,Sugui JA,Kwon-Chung KJ,Warris A

更新日期：2011-02-01 00:00:00

abstract：:Streptococcus mutans, a major oral pathogen responsible for dental caries formation, possesses a variety of mechanisms for survival in the human oral cavity, where the conditions of the external environment are diverse and in a constant state of flux. The formation of biofilms, survival under conditions of acidic pH, ...

journal_title：Infection and immunity

authors： Chong P,Drake L,Biswas I

更新日期：2008-07-01 00:00:00

abstract：:To look for a possible correlation between the virulence of Rhodococcus equi and its cytokine-inducing capacity, we evaluated intracellular survival and measured cytokine induction by mouse macrophages infected with a virulent strain containing an 85-kb plasmid and expressing VapA (103+), its avirulent plasmid-cured d...

journal_title：Infection and immunity

authors： Giguère S,Prescott JF

更新日期：1998-05-01 00:00:00

abstract：:The ability of human clinical isolates of Yersinia enterocolitica to interact with HEp-2 cells was found to vary considerably between the serotypes O:3, O:8, and O:9. Although all three serotypes adhered initially to the cell surface, regardless of incubation temperature of the bacterial inoculum or presence of the 40...

journal_title：Infection and immunity

authors： Lassen J,Kapperud G

更新日期：1986-04-01 00:00:00

abstract：:Mammalian hosts often develop distinct immune response against the diverse parasitic helminths that have evolved for immune evasion. Interleukin-25 (IL-25), an IL-17 cytokine family member, plays a key role in initiating the protective immunity against several parasitic helminths; however, the involvement and underlyi...

journal_title：Infection and immunity

authors： Angkasekwinai P,Srimanote P,Wang YH,Pootong A,Sakolvaree Y,Pattanapanyasat K,Chaicumpa W,Chaiyaroj S,Dong C

更新日期：2013-10-01 00:00:00

abstract：:Helicobacter pylori maintains colonization in its human host using a limited set of taxis sensors. TlpD is a proposed energy taxis sensor of H. pylori and dominant under environmental conditions of low bacterial energy yield. We studied the impact of H. pylori TlpD on colonization in vivo using a gerbil infection mode...

journal_title：Infection and immunity

authors： Behrens W,Schweinitzer T,Bal J,Dorsch M,Bleich A,Kops F,Brenneke B,Didelot X,Suerbaum S,Josenhans C

更新日期：2013-10-01 00:00:00

abstract：:Acquired cellular immunity to infection with Mycobacterium tuberculosis is believed to reside in the capacity of mononuclear phagocytes of immunized animals to inhibit intracellular multiplication of the parasite. However, in macrophage tissue culture systems, it has been customary to employ streptomycin in the medium...

journal_title：Infection and immunity

authors： Patterson RJ,Youmans GP

更新日期：1970-01-01 00:00:00

abstract：:Cells of Yersinia pestis strain EV76 are known to cease growth after a shift from 26 to 37 degrees C in neutral Ca2+-deficient medium; this effect is potentiated by Mg2+. With 2.5 mM Mg2+ and no added Ca2+, restriction was relaxed at elevated pH at which maximum cell yields occurred in the presence of 20 mM exogenous ...

journal_title：Infection and immunity

authors： Zahorchak RJ,Brubaker RR

更新日期：1982-12-01 00:00:00

abstract：:Edema disease (ED) of weanling pigs is caused by an infection with Escherichia coli that produces Shiga-like toxin II variant (SLT-IIv). Pathology identical to that caused by ED can be duplicated in pigs that are injected with less than 10 ng of purified SLT-IIv per kg of body weight. Therefore, SLT-IIv was mutated to...

journal_title：Infection and immunity

authors： Gordon VM,Whipp SC,Moon HW,O'Brien AD,Samuel JE

更新日期：1992-02-01 00:00:00

abstract：:Pools of rat antiserum to Plasmodium berghei had different levels of protective activity as assessed by a passive transfer test. Preincubation of parasite inocula with an effective pool before injection did not significantly enhance protective activity. Removal of the antiserum from preincubated parasite inocula aboli...

journal_title：Infection and immunity

authors： Brown IN,Phillips RS

更新日期：1974-12-01 00:00:00

abstract：:Infection of C57BL/6 mice with the third-stage larvae of Brugia pahangi results in a rapid expansion of NK1.1(+) T cells in the spleen and draining lymph nodes. NK T cells produced interleukin-4 in the spleen within 24 h of infection, and these cells were CD4(-). ...

journal_title：Infection and immunity

authors： Balmer P,Devaney E

更新日期：2002-04-01 00:00:00

abstract：:Mice with a null deletion mutation in the gamma interferon (IFN-gamma) receptor gene were used to study the role of IFN-gamma responsiveness during experimental pulmonary cryptococcosis. Cryptococcus neoformans was inoculated intratracheally into mice lacking the IFN-gamma receptor gene (IFN-gammaR-/-) and into contro...

journal_title：Infection and immunity

authors： Chen GH,McDonald RA,Wells JC,Huffnagle GB,Lukacs NW,Toews GB

更新日期：2005-03-01 00:00:00

abstract：:The fibronectin-binding proteins (FnBPs) of Staphylococcus aureus are believed to be implicated in the pathogen's adherence to and colonization of bovine mammary glands, thus leading to infectious mastitis. In vitro studies have shown that FnBPs help the adhesion of the pathogen to bovine mammary epithelial cells. How...

journal_title：Infection and immunity

authors： Brouillette E,Talbot BG,Malouin F

更新日期：2003-04-01 00:00:00

abstract：:Free lipid A of Bordetella pertussis, Neisseria meningitidis, and Escherichia coli lipopolysaccharide (LPS) was prepared by hydrolysis in acetate buffer (pH 4.5); in addition, lipid A from B. pertussis and E. coli was prepared by hydrolysis in mineral acid (HCl). The precipitates obtained were purified by extraction m...

journal_title：Infection and immunity

authors： Caroff M,Cavaillon JM,Fitting C,Haeffner-Cavaillon N

更新日期：1986-11-01 00:00:00

abstract：:Infection of resistant or susceptible mice with Trichuris muris provokes mesenteric lymph node responses which are polarized towards Th2 or Th1, respectively. These responses are well documented in the literature. In contrast, little is known about the local responses occurring within the infected intestine. Through m...

journal_title：Infection and immunity

authors： Datta R,deSchoolmeester ML,Hedeler C,Paton NW,Brass AM,Else KJ

更新日期：2005-07-01 00:00:00

abstract：:Helicobacter pylori colonizes the gastric mucosa and secretes a pore-forming toxin (VacA). Two main types of VacA, m1 and m2, can be distinguished by phylogenetic analysis. Type m1 forms of VacA have been extensively studied, but there has been relatively little study of m2 forms. In this study, we generated H. pylori...

journal_title：Infection and immunity

authors： Caston RR,Sierra JC,Foegeding NJ,Truelock MD,Campbell AM,Frick-Cheng AE,Bimczok D,Wilson KT,McClain MS,Cover TL

更新日期：2020-05-20 00:00:00

abstract：:CD8 T cells are effective mediators of specific immunity to infection by Listeria monocytogenes, a bacterial pathogen that initially infects macrophages in the spleen and liver and subsequently spreads to hepatocytes and unidentified parenchymal cells in the spleen. To identify the in vivo target cells of L. monocytog...

journal_title：Infection and immunity

authors： Harty JT,Bevan MJ

更新日期：1996-09-01 00:00:00

abstract：:Brucella abortus is a facultative intracellular bacterial pathogen that causes abortion in domestic animals and undulant fever in humans. The mechanism of virulence of Brucella spp. is not fully understood yet. Furthermore, genes that allow Brucella to reach the intracellular niche and to interact with host cells need...

journal_title：Infection and immunity

authors： Rosinha GM,Freitas DA,Miyoshi A,Azevedo V,Campos E,Cravero SL,Rossetti O,Splitter G,Oliveira SC

更新日期：2002-09-01 00:00:00

abstract：:The Chagas' disease parasite Trypanosoma cruzi commonly infects humans through skin abrasions or mucosa from reduviid bug excreta. Yet most studies on animal models start with subcutaneous or intraperitoneal injections, a distant approximation of the skin abrasion route. We show here that atraumatic placement of T. cr...

journal_title：Infection and immunity

authors： Caradonna K,Pereiraperrin M

更新日期：2009-04-01 00:00:00

abstract：:Monoclonal antibodies to Trichomonas vaginalis were prepared by immunizing mice with a cloned isolate of T. vaginalis. Eight antibodies reacted with the same four isolates or strains but did not react with the other T. vaginalis strains or isolates tested. All eight antibodies reacted uniformly with both the body and ...

journal_title：Infection and immunity

authors： Torian BE,Connelly RJ,Stephens RS,Stibbs HH

更新日期：1984-01-01 00:00:00