Cytokine induction in murine macrophages infected with virulent and avirulent Rhodococcus equi.

abstract：:gammaG-globulin from nonimmunized rabbits and from rabbits immunized with various bacteria reacted in the immunofluorescence technique with protein A-containing Staphylococcus aureus. Pepsin digestion of most immunoglobulin preparations eliminated the reaction, thus showing that the Fc fragment is involved and that th...

journal_title：Infection and immunity

authors： Forsgren A,Forsum U

更新日期：1970-10-01 00:00:00

abstract：:Exoenzyme S (ExoS), an ADP-ribosylating enzyme produced by the opportunistic pathogen Pseudomonas aeruginosa, is directly translocated into eukaryotic cells by bacterial contact. Within the cell, ExoS ADP-ribosylates the cell signaling protein Ras and causes inhibition of DNA synthesis and alterations in cytoskeletal ...

journal_title：Infection and immunity

authors： Olson JC,Fraylick JE,McGuffie EM,Dolan KM,Yahr TL,Frank DW,Vincent TS

更新日期：1999-06-01 00:00:00

abstract：:In bacterial infections, mononuclear and polymorphonuclear phagocytes are key components of host defenses. Recent investigations have indicated that chemokines are able to recruit and activate phagocytes. In particular, interleukin-8 (IL-8) attracts polymorphonuclear leukocytes (PMNs), while monocyte chemoattractant p...

journal_title：Infection and immunity

authors： Tonetti MS,Imboden MA,Gerber L,Lang NP,Laissue J,Mueller C

更新日期：1994-09-01 00:00:00

abstract：:Passive transfer of antibody may be useful for preexposure prophylaxis against biological agents used as weapons of terror, such as Bacillus anthracis. Studies were performed to evaluate the ability of anthrax antiprotective antigen (anti-PA) and antilethal factor (anti-LF) neutralizing monoclonal antibodies (mAbs) to...

journal_title：Infection and immunity

authors： Staats HF,Alam SM,Scearce RM,Kirwan SM,Zhang JX,Gwinn WM,Haynes BF

更新日期：2007-11-01 00:00:00

abstract：:Monoclonal antibodies (MAbs) specific for Plasmodium falciparum rhoptry-associated protein 1 (RAP-1) were generated and tested for inhibition of parasite growth in vitro. The majority of indirect immunofluorescence assay (IFA)-positive MAbs raised against recombinant RAP-1 positions 23 to 711 (rRAP-1(23-711)) recogniz...

journal_title：Infection and immunity

authors： Moreno R,Pöltl-Frank F,Stüber D,Matile H,Mutz M,Weiss NA,Pluschke G

更新日期：2001-04-01 00:00:00

abstract：:Toxoplasma gondii infection in pregnant women may result in abortion or in fetal teratogenesis; however, the underlying mechanisms are still unclear. In this paper, based on a murine model, we showed that maternal infection with RH strain T. gondii tachyzoites induced elevated production of reactive oxygen species (RO...

journal_title：Infection and immunity

authors： Xu X,Liu T,Zhang A,Huo X,Luo Q,Chen Z,Yu L,Li Q,Liu L,Lun ZR,Shen J

更新日期：2012-06-01 00:00:00

abstract：:Monolayer cultures of LLC-MK2 rhesus monkey kidney cells become persistently infected with simian virus 40 after infection at input multiplicities of 100, 10, or 1 plaque-forming unit per cell. After 3 weeks, all cells of the cultures infected at a multiplicity of 1 plaque-forming unit per cell produced the simian vir...

journal_title：Infection and immunity

authors： Norkin LC

更新日期：1977-12-01 00:00:00

abstract：:We studied the antigenicity of a wild-type flagellate and motile (F+M+) Campylobacter jejuni strain (81116) and two daughter mutants, one flagellate and immotile (F+M-) and one aflagellate and immotile (F-M-). By sodium dodecyl sulfate-polyacrylamide gel electrophoresis of acid-extracted surface proteins, a 63-kilodal...

journal_title：Infection and immunity

authors： Blaser MJ,Hopkins JA,Perez-Perez GI,Cody HJ,Newell DG

更新日期：1986-07-01 00:00:00

abstract：:Murine bone marrow-derived dendritic cells (DC) can phagocytose and process Salmonella enterica serovar Typhimurium for peptide presentation on major histocompatibility complex class I (MHC-I) and MHC-II molecules. To investigate if a serovar Typhimurium encounter with DC induces maturation and downregulates their abi...

journal_title：Infection and immunity

authors： Svensson M,Johansson C,Wick MJ

更新日期：2000-11-01 00:00:00

abstract：:The adherence of several strains of Escherichia coli to human buccal epithelial cells was studied, using cells obtained from five groups: healthy adults, healthy children, children with acute diarrhea, children with persistent diarrhea associated with cryptosporidial parasites, and children with noncryptosporidial per...

journal_title：Infection and immunity

authors： Walser BL,Newman RD,Lima AA,Guerrant RL

更新日期：1992-11-01 00:00:00

abstract：:The effector mechanism, which operates against challenge parasites in the lungs of C57BL/6 mice vaccinated once with irradiated cercariae of Schistosoma mansoni, is mediated by CD4+ T helper lymphocytes. However, adoptive transfer of immunity from vaccinated donors to naive recipients by using sensitized T cells has n...

journal_title：Infection and immunity

authors： Coulson PS,Wilson RA

更新日期：1997-01-01 00:00:00

abstract：:A major surface antigen of Trichomonas vaginalis was purified by using three independently derived monoclonal antibodies (two immunoglobulin M and one immunoglobulin G1) prepared against T. vaginalis PHS-2J. A 115,000-molecular-weight antigen and one or more components with a molecular weight of 58,000 to 64,000 were ...

journal_title：Infection and immunity

authors： Connelly RJ,Torian BE,Stibbs HH

更新日期：1985-08-01 00:00:00

abstract：:Pseudomonas aeruginosa can invade corneal epithelial cells and translocates multilayered corneal epithelia in vitro, but it does not penetrate the intact corneal epithelium in vivo. In healthy corneas, the epithelium is separated from the underlying stroma by a basement membrane containing extracellular matrix protein...

journal_title：Infection and immunity

authors： Alarcon I,Kwan L,Yu C,Evans DJ,Fleiszig SM

更新日期：2009-08-01 00:00:00

abstract：:The type III secretion system (T3SS) plays a crucial role in the pathogenesis of many Gram-negative bacteria, including Edwardsiella tarda, an important fish pathogen. Within the E. tarda T3SS, there are three proteins (EsaB/EsaL/EsaM) that are homologous to proteins present in many other bacteria, including SpiC/SsaL...

journal_title：Infection and immunity

authors： Liu LY,Nie P,Yu HB,Xie HX

更新日期：2017-08-18 00:00:00

abstract：:The ability of Klebsiella pneumoniae strains to resist the bactericidal activity of serum was quantitated. The K. pneumoniae strains tested included mutants lacking the capsular polysaccharide and mutants having a modified lipopolysaccharide structure. The last mutants were obtained as phage-resistant mutants, and the...

journal_title：Infection and immunity

authors： Tomás JM,Benedí VJ,Ciurana B,Jofre J

更新日期：1986-10-01 00:00:00

abstract：:The she gene of Shigella flexneri 2a, which also harbors the internal enterotoxin genes set1A and set1B (F. R. Noriega, GenBank accession no. U35656, 1995) encodes a homolog of the virulence-related immunoglobulin A (IgA) protease-like family of secreted proteins, Tsh, EspC, SepA, and Hap, from an avian pathogenic Esc...

journal_title：Infection and immunity

authors： Rajakumar K,Sasakawa C,Adler B

更新日期：1997-11-01 00:00:00

abstract：:In vivo accumulation of D-serine by Escherichia coli CFT073 leads to elevated expression of PAP fimbriae and hemolysin by an unknown mechanism. Loss of D-serine catabolism by CFT073 leads to a competitive advantage during murine urinary tract infection (UTI), but loss of both D- and L-serine catabolism results in atte...

journal_title：Infection and immunity

authors： Anfora AT,Halladin DK,Haugen BJ,Welch RA

更新日期：2008-12-01 00:00:00

abstract：:PtlH is an essential component of the Ptl system, the type IV transporter responsible for secretion of pertussis toxin (PT) across the outer membrane of Bordetella pertussis. The nine Ptl proteins are believed to interact to form a membrane-spanning apparatus through which the toxin is secreted. In this study, we moni...

journal_title：Infection and immunity

authors： Verma A,Burns DL

更新日期：2007-05-01 00:00:00

abstract：:Cells of the marine fish pathogen Vibrio anguillarum 775 harboring a plasmid associated with virulence can grow unaffected in the presence of iron-binding compounds such as transferrin. In contrast, the growth of isogenic plasmidless derivatives is inhibited by the presence of iron chelators. Radioactive from (55Fe3+)...

journal_title：Infection and immunity

authors： Crosa JH,Hodges LL

更新日期：1981-01-01 00:00:00

abstract：:Borrelia burgdorferi encodes a functional homolog of canonical Lon protease termed Lon-2. In addition, B. burgdorferi encodes a second Lon homolog called Lon-1. Recent studies suggest that Lon-1 may function differently from the prototypical Lon protease. However, the function of Lon-1 in B. burgdorferi biology remain...

journal_title：Infection and immunity

authors： Thompson C,Mason C,Parrilla S,Ouyang Z

更新日期：2020-05-20 00:00:00

abstract：:The interaction between bacteria and fibronectin is believed to play an important role in the pathogenicity of clinically important Gram-positive cocci. In the present study, we identified a gene encoding a predicted fibronectin-binding protein of Enterococcus faecium (fnm), a homologue of Streptococcus pneumoniae pav...

journal_title：Infection and immunity

authors： Somarajan SR,La Rosa SL,Singh KV,Roh JH,Höök M,Murray BE

更新日期：2015-12-01 00:00:00

abstract：:The invasion of Rickettsia tsutsugamushi, Gilliam strain, into guinea pig polymorphonuclear leukocytes (PMNs) and the localization and distribution of tracers were followed during the process by electron microscopy. The seven tracers used were: cationized ferritin, ferritin, thorium dioxide (ThO2), carbon particles, l...

journal_title：Infection and immunity

authors： Rikihisa Y,Ito S

更新日期：1980-10-01 00:00:00

abstract：:Citrate is a ubiquitous compound and can be utilized by many bacterial species, including enteric pathogens, as a carbon and energy source. Genes involved in citrate utilization have been extensively studied in some enteric bacteria, such as Klebsiella pneumoniae; however, their role in pathogenesis is still not clear...

journal_title：Infection and immunity

authors： Liu M,Hao G,Li Z,Zhou Y,Garcia-Sillas R,Li J,Wang H,Kan B,Zhu J

更新日期：2019-02-21 00:00:00

abstract：:Peru-15 is a live attenuated oral vaccine derived from a Vibrio cholerae O1 El Tor Inaba strain by a series of deletions and modifications, including deletion of the entire CT genetic element. Peru-15 is also a stable, motility-defective strain and is unable to recombine with homologous DNA. We wished to determine whe...

journal_title：Infection and immunity

authors： Cohen MB,Giannella RA,Bean J,Taylor DN,Parker S,Hoeper A,Wowk S,Hawkins J,Kochi SK,Schiff G,Killeen KP

更新日期：2002-04-01 00:00:00

abstract：:We report here on the isolation of isogenic strains of Aeromonas hydrophila AB3 deleted for a segment of the aerolysin gene. All aer mutants obtained lacked the 49-kilodalton aerolysin gene product and were neither hemolytic for blood erythrocytes nor cytotoxic for Chinese hamster ovary tissue culture cells. One such ...

journal_title：Infection and immunity

authors： Chakraborty T,Huhle B,Hof H,Bergbauer H,Goebel W

更新日期：1987-09-01 00:00:00

abstract：:The heparin-binding hemagglutinin (HBHA) of Mycobacterium tuberculosis is a surface-expressed adhesin that can affect binding to host cells via a unique, methylated, carboxyl-terminal, lysine-, alanine-, and proline-rich repeat region. It has been implicated in extrapulmonary dissemination of M. tuberculosis from the ...

journal_title：Infection and immunity

authors： Parra M,Pickett T,Delogu G,Dheenadhayalan V,Debrie AS,Locht C,Brennan MJ

更新日期：2004-12-01 00:00:00

abstract：:NF-κB is a critical regulator of gene expression during severe infections. NF-κB comprises homo- and heterodimers of proteins from the Rel family. Among them, p50 and p65 have been clearly implicated in the pathophysiology of sepsis. In contrast, the role of cRel in sepsis is still controversial and has been poorly st...

journal_title：Infection and immunity

authors： Courtine E,Pène F,Cagnard N,Toubiana J,Fitting C,Brocheton J,Rousseau C,Gerondakis S,Chiche JD,Ouaaz F,Mira JP

更新日期：2011-05-01 00:00:00

abstract：:Studies conducted with F1 and F2 progeny of crosses between strains of inbred mice that differ greatly in their capacity to make an antibody response to type III pneumococcal polysaccharide, dextran B-1355, and lipopolysaccharide from Escherichia coli 0113 have shown that multiple genes influence the magnitude of the ...

journal_title：Infection and immunity

authors： Baker PJ,Rudbach JA,Prescott B,Caldes G,Evans C,Stashak PW

更新日期：1984-07-01 00:00:00

abstract：:The protein P2 comprises a large proportion of the outer membrane of nontypable Haemophilus influenzae and functions as a porin. In view of the importance of the protein as a surface antigen, the present study was designed to purify and analyze P2 with particular emphasis on detection of antigenic determinants express...

journal_title：Infection and immunity

authors： Murphy TF,Bartos LC

更新日期：1988-05-01 00:00:00

abstract：:This study determined the role of crl in the production of curli by, the hemagglutination activity of, and fibronectin binding by avian pathogenic Escherichia coli chi 7122. Curli, an extracellular structure that binds fibronectin, was recently described (A. Olsén, A. Jonsson, and S. Normark, Nature [London] 338:652-6...

journal_title：Infection and immunity

authors： Provence DL,Curtiss R 3rd

更新日期：1992-11-01 00:00:00