Structural and antigenic conservation of the P2 porin protein among strains of Haemophilus influenzae type b.

abstract：:The effects of tolerance to Escherichia coli endotoxin on the phagocytic and bactericidal activity of the hepatic reticuloendothelial system against viable E. coli were examined using ex vivo perfused rat livers. Livers were isolated from control and endotoxin-tolerant rats and perfused with a medium containing 5% hom...

journal_title：Infection and immunity

authors： Ruggiero G,Andreana A,Utili R,Galante D

更新日期：1980-03-01 00:00:00

abstract：:Shiga toxin type 1 (Stx1) belongs to the Shiga family of bipartite AB toxins that inactivate eukaryotic 60S ribosomes. The A subunit of Stxs are N-glycosidases that share structural and functional features in their catalytic center and in an internal hydrophobic region that shows strong transmembrane propensity. Both ...

journal_title：Infection and immunity

authors： Suhan ML,Hovde CJ

更新日期：1998-11-01 00:00:00

abstract：:The 25-kb linear plasmid lp25 and one of the 28-kb linear plasmids (lp28-1) are required for experimental infection in Borrelia burgdorferi, the etiologic agent of Lyme disease. The loss of these plasmids either eliminates infectivity (lp25) or significantly increases the 50% infective dose during a 2-week infection p...

journal_title：Infection and immunity

authors： Labandeira-Rey M,Seshu J,Skare JT

更新日期：2003-08-01 00:00:00

abstract：:Streptococcus mutans, a major pathogen of dental caries, is considered one of the causative agents of infective endocarditis (IE). Recently, bacterial DNA encoding 120-kDa cell surface collagen-binding proteins (CBPs) has frequently been detected from S. mutans-positive IE patients. In addition, some of the CBP-positi...

journal_title：Infection and immunity

authors： Otsugu M,Nomura R,Matayoshi S,Teramoto N,Nakano K

更新日期：2017-11-17 00:00:00

abstract：:Human enterotoxigenic Escherichia coli (ETEC) producing colonization factor antigen III (CFA/III) and coli surface antigens 4, 5, and 6 (CS4, CS5, and CS6) of CFA/IV were examined ultrastructurally and for ability to adhere to human small intestinal enterocytes and to cultured human intestinal mucosa. Strains of serot...

journal_title：Infection and immunity

authors： Knutton S,McConnell MM,Rowe B,McNeish AS

更新日期：1989-11-01 00:00:00

abstract：:Changes in the structural components of the Streptococcus pyogenes membrane between exponential and early stationary phases of growth are reported. The overall protein composition ranged from 70 to 73% of the dry weight of the membranes, irrespective of the phase of growth from which they were isolated. Amino acid ana...

journal_title：Infection and immunity

authors： van de Rijn I,Kessler RE

更新日期：1979-12-01 00:00:00

abstract：:The adsorption of (3)H-labeled Streptococcus mutans 6715 cells to disks of hydroxyapatite (HA) was studied. The number of streptococci that adsorbed was logarithmically related to the concentration of cells available up to at least 2 x 10(8) per ml; equilibrium occurred within 45 min. Assay reliability was verified by...

journal_title：Infection and immunity

authors： Clark WB,Gibbons RJ

更新日期：1977-11-01 00:00:00

abstract：:The M1inv+ subclone of M1 group A streptococci that spread globally in the late 1980s and early 1990s was previously identified by restriction fragment length polymorphism (RFLP), M protein, and SpeA exotoxin sequence analyses. Strains representing this subclone were characterized with regard to carriage of bacterioph...

journal_title：Infection and immunity

authors： Cleary PP,LaPenta D,Vessela R,Lam H,Cue D

更新日期：1998-11-01 00:00:00

abstract：:The role of capsule in the adherence of Haemophilus influenzae type b to human epithelial cells in vitro was examined. A group of 30 nonadherent isolates did not differ in degree of encapsulation compared with their respective adherent variants. Furthermore, capsule-deficient mutants of both nonadherent and adherent v...

journal_title：Infection and immunity

authors： LiPuma JJ,Gilsdorf JR

更新日期：1987-09-01 00:00:00

abstract：:The action of trehalose-6, 6'-dimycolate (cord factor) of Mycobacterium tuberculosis to induce site II-specific inhibition of mitochondrial oxidative phosphorylation and to stimulate adenosine triphosphatase activity was neutralized by its specific antibody. The activity was restored after dissociation of cord factor ...

journal_title：Infection and immunity

authors： Kato M

更新日期：1974-07-01 00:00:00

abstract：:In mice infected with virulent blood (trypomastigote) forms of Trypanosoma cruzi, complement depletion with cobra venom factor caused a marked exacerbation of the disease evidenced by significantly increased parasitemia levels and early mortality as compared with those of untreated infected animals. The effect was gre...

journal_title：Infection and immunity

authors： Budzko DB,Pizzimenti MC,Kierszenbaum F

更新日期：1975-01-01 00:00:00

abstract：:Brucella spp. are intracellular bacteria that cause the most frequent zoonosis in the world. Although recent work has advanced the field of Brucella vaccine development, there remains no safe human vaccine. In order to produce a safe and effective human vaccine, the immune response to Brucella spp. requires greater un...

journal_title：Infection and immunity

authors： Durward MA,Harms J,Magnani DM,Eskra L,Splitter GA

更新日期：2010-01-01 00:00:00

abstract：:Aerobic microorganisms were isolated and identified from 9 of 10 malignant tissues aseptically obtained from surgical patients. The organisms isolated are species commonly associated with the flora of the human body. When these cancer-associated organisms were grown in Trypticase soy broth (BBL Microbiology Systems), ...

journal_title：Infection and immunity

authors： Backus BT,Affronti LF

更新日期：1981-06-01 00:00:00

abstract：:Several strains of group B Streptococcus agalactiae were found to be lethal for young adult rats. When bacteria were heat killed and then injected intraperitoneally into rats, rapid death (14 to 18 h) of the rats occurred, characterized by labored breathing, hemolyzed serum, hemoglobinuria, and subungual hemorrhages. ...

journal_title：Infection and immunity

authors： Warejcka DJ,Goodrum KJ,Spitznagel JK

更新日期：1985-05-01 00:00:00

abstract：:The cytokine response to the agent of human granulocytic ehrlichiosis (HGE) was assessed in a murine infection model and the role of gamma interferon (IFN-gamma), a cytokine that is crucial for host defenses against intracellular pathogens, was investigated by using IFN-gamma-deficient mice. The agent of HGE (aoHGE) i...

journal_title：Infection and immunity

authors： Akkoyunlu M,Fikrig E

更新日期：2000-04-01 00:00:00

abstract：:Antisera were produced by inoculation of mycoplasma cells grown in PPLO broth supplemented with rabbit serum alone or rabbit serum plus Freund complete or incomplete adjuvant. By using an enzyme-linked immunosorbent assay, immunoglobulin G antibodies to cholesterol were detected in antisera to mycoplasmas (Mycoplasma ...

journal_title：Infection and immunity

authors： Watanabe T,Kumazawa T

更新日期：1991-06-01 00:00:00

abstract：:Current evidence indicates that Mycobacterium avium infection in patients with AIDS is acquired mostly through the gastrointestinal (GI) tract and that M. avium binds to and invades GI mucosal cells in vitro. Since M. avium is exposed to specific environmental conditions in the GI tract such as changes in pH, low oxyg...

journal_title：Infection and immunity

authors： Bermudez LE,Petrofsky M,Goodman J

更新日期：1997-09-01 00:00:00

abstract：:Vibrio cholerae O1 has two biotypes, El Tor and Classical, and the latter is now presumed to be extinct in nature. Under carbohydrate-rich growth conditions, El Tor biotype strains produce the neutral fermentation end product 2,3-butanediol (2,3-BD), which prevents accumulation of organic acids from mixed acid ferment...

journal_title：Infection and immunity

authors： Bari W,Song YJ,Yoon SS

更新日期：2011-08-01 00:00:00

abstract：:The effects of heat and chemical inactivation on the antigenicity and immunogenicity of Vibrio cholerae 1418 in rabbits were studied. V. cholerae 1418 was inactivated with heat and chemical inactivants (phenol or Formalin) alone or in combination. Enzyme-linked immunoassay systems employing whole cells of V. cholerae ...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Fürer E,Germanier R

更新日期：1982-10-01 00:00:00

abstract：:The biological activity of C-ASWS, an alkali-soluble, water-soluble cell wall antigen isolated from mycelial-phase cells of Coccidioides immitis, was compared with that of a commercial coccidioidin (CDN; Cutter Laboratories); CDN-TS, a toluene-induced lysate of mycelial-phase cells; and spherulin, a spherule-derived e...

journal_title：Infection and immunity

authors： Cox RA,Brummer E,Lecara G

更新日期：1977-03-01 00:00:00

abstract：:Previous attempts to induce mucosal antibodies in rhesus monkeys by enteric immunization have resulted in only modest and short-lived responses, dominated by immunoglobulin M (IgM) antibodies in the plasma. In this study, two groups of rhesus monkeys were immunized intranasally three times at 2-week intervals with a b...

journal_title：Infection and immunity

authors： Russell MW,Moldoveanu Z,White PL,Sibert GJ,Mestecky J,Michalek S M

更新日期：1996-04-01 00:00:00

abstract：:A preparation procedure for scanning electron microscopy was developed by which gononcoccal colonies can be studied directly on the agar surface. After glutaraldehyde fixation directly in petri dishes, small agar pieces were cut out and dehydrated stepwise in increasing concentrations of ethanol. The blocks were there...

journal_title：Infection and immunity

authors： Elmros T,Hörstedt P,Winblad B

更新日期：1975-09-01 00:00:00

abstract：:Murine embryo fibroblasts (MEF) were found to secrete tumor necrosis factor (TNF) in response to stimulation with endotoxin. Endotoxin-induced TNF production by MEF was inhibited by cycloheximide. However, reversal of the effect of this inhibitor on protein synthesis results in TNF being secreted in amounts equivalent...

journal_title：Infection and immunity

authors： Havell EA,Rogerson BJ

更新日期：1993-05-01 00:00:00

abstract：:Development of hemolytic uremic syndrome (HUS) after infection by Shigella dysenteriae 1 or enterohemorrhagic Escherichia coli has been associated with the production of Shiga toxins (verotoxins). The putative target of Shiga toxins in HUS is the renal microvascular endothelium. This report shows that preincubation of...

journal_title：Infection and immunity

authors： Kaye SA,Louise CB,Boyd B,Lingwood CA,Obrig TG

更新日期：1993-09-01 00:00:00

abstract：:Anaplasma marginale subsp. centrale was the first vaccine used to protect against a rickettsial disease and is still in widespread use a century later. As its use preceded development of either cryopreservation or cell culture, the vaccine strain was maintained for decades by sequential passage among donor animals, ex...

journal_title：Infection and immunity

authors： Herndon DR,Ueti MW,Reif KE,Noh SM,Brayton KA,Agnes JT,Palmer GH

更新日期：2013-05-01 00:00:00

abstract：:Pseudomonas aeruginosa exotoxin A (PA), a potent protein synthesis inhibitor, was found to be a weak T-cell mitogen for murine splenocytes. Maximal stimulation of [3H]thymidine incorporation was obtained with 10 to 100 ng of toxin per ml following a 4-day induction. PA was also shown to be a polyclonal activator of cy...

journal_title：Infection and immunity

authors： Zehavi-Willner T

更新日期：1988-01-01 00:00:00

abstract：:We studied the influence of staphylococcal toxic shock syndrome toxin 1 and streptococcal erythrogenic (pyrogenic) toxin A (ETA) on intact and digitonin-permeabilized human polymorphonuclear granulocytes (PMNs). As was shown by reversed-phase high-performance liquid chromatography analysis, toxic shock syndrome toxin ...

journal_title：Infection and immunity

authors： Hensler T,Köller M,Geoffroy C,Alouf JE,König W

更新日期：1993-03-01 00:00:00

abstract：:Pathogen attachment to host cells is a key process during infection, and inhibition of pathogen adhesion is a promising approach to the prevention of infectious disease. We have previously shown that multivalent adhesion molecules (MAMs) are abundant in both pathogenic and commensal bacterial species, mediate early at...

journal_title：Infection and immunity

authors： Al-Saedi F,Stones DH,Vaz DP,Krachler AM

更新日期：2016-05-24 00:00:00

abstract：:Whole-genome sequencing analysis of ∼800 strains of group A Streptococcus (GAS) found that the gene encoding the multiple virulence gene regulator of GAS (mga) is highly polymorphic in serotype M59 strains but not in strains of other serotypes. To help understand the molecular mechanism of gene regulation by Mga and i...

journal_title：Infection and immunity

authors： Sanson M,Makthal N,Gavagan M,Cantu C,Olsen RJ,Musser JM,Kumaraswami M

更新日期：2015-06-01 00:00:00

abstract：:Vibrio vulnificus is an oyster-associated bacterial pathogen that causes life-threatening fulminating septicemia and necrotizing wound infections in humans. The capsular polysaccharide of V. vulnificus (VvPS) is critical for virulence. Previously we showed that active immunization of mice with a VvPS-tetanus toxoid (V...

journal_title：Infection and immunity

authors： Devi SJ,Hayat U,Powell JL,Morris JG Jr

更新日期：1996-06-01 00:00:00