HLA-restricted T lymphocyte-mediated cytotoxicity against herpes simplex virus-infected cells in humans.

abstract：:Characteristics of four transmissible gastroenteritis (TGE) virus field strains (Miller, Purdue, Bl, and V203) and four cell culture-attenuated strains (Purdue, SH, CKp, and Bl) were studied to find methods of differentiation between the two groups of viruses. TGE field virus strains did not replicate as well as atten...

journal_title：Infection and immunity

authors： Hess RG,Bachmann PA

更新日期：1976-06-01 00:00:00

abstract：:Restoration of the ability of hypogammaglobulinemic serum to support opsonophagocytosis and intracellular killing of Bacteroides fragilis and Bacteroides thetaiotaomicron by human polymorphonuclear leukocytes was achieved by supplementation with normal human immunoglobulin M, but not with normal human immunoglobulin G...

journal_title：Infection and immunity

authors： Bjornson AB,Bjornson HS,Kitko BP

更新日期：1980-05-01 00:00:00

abstract：:Isolates of Thermoplasma acidophilum were divided into serological groups based on immunodiffusion studies of solubilized-membrane preparations. ...

journal_title：Infection and immunity

authors： Bohlool BB,Brock TD

更新日期：1974-07-01 00:00:00

abstract：:Urease from ureaplasmas was purified by immunoaffinity chromatography, and the N-terminal amino acid sequence was determined for two of the three subunits. These sequences were used to design primers for a polymerase chain reaction (PCR) that amplified most of the gene coding for one of the subunits. By using a novel ...

journal_title：Infection and immunity

authors： Willoughby JJ,Russell WC,Thirkell D,Burdon MG

更新日期：1991-07-01 00:00:00

abstract：:The Th1/Th2 cytokines involved in human periodontitis remain unclear; therefore, we established a humanized mouse model to investigate this issue in Actinobacillus actinomycetemcomitans-mediated periodontal infection. Quantitative-PCR analysis clearly demonstrates a predominantly mixed Th1 and Th2 expression profile a...

journal_title：Infection and immunity

authors： Teng YT

更新日期：2002-09-01 00:00:00

abstract：:The HT29MTXE12 (E12) cell line harbors an adherent mucus layer, providing a novel technique to model mucosal infection in vitro. In this study, we have characterized the interaction of Campylobacter jejuni with the E12 cell line and exploited its unique mucus layer to examine the potential efficacy of probiotic treatm...

journal_title：Infection and immunity

authors： Alemka A,Clyne M,Shanahan F,Tompkins T,Corcionivoschi N,Bourke B

更新日期：2010-06-01 00:00:00

abstract：:Defensins are antibiotic peptides expressed in human and animal myeloid and epithelial cells. Due to the limited availability of natural peptides, the properties of human epithelial defensins have not been studied. We assayed the microbicidal activity of recombinant human intestinal defensin 5 (rHD-5) in the presence ...

journal_title：Infection and immunity

authors： Porter EM,van Dam E,Valore EV,Ganz T

更新日期：1997-06-01 00:00:00

abstract：:Colony variants of Neisseria gonorrhoeae differ in their interactions with eucaryotic cells. When gonococci were cultivated with HeLa cell monolayers, the opacity phenotype (Op) became increasingly dominant in the subpopulation of organisms which adhered to the HeLa cells. Once bound, Op organisms displayed very low l...

journal_title：Infection and immunity

authors： Bessen D,Gotschlich EC

更新日期：1986-10-01 00:00:00

abstract：:Streptococcus agalactiae (group B streptococcus [GBS]) is the leading cause of neonatal pneumonia, sepsis, and meningitis. An in silico genome analysis indicated that GBS strain NEM316 encodes 35 proteins containing an LPXTG motif which are thought to be covalently linked to the peptidoglycan by an enzyme called sorta...

journal_title：Infection and immunity

authors： Lalioui L,Pellegrini E,Dramsi S,Baptista M,Bourgeois N,Doucet-Populaire F,Rusniok C,Zouine M,Glaser P,Kunst F,Poyart C,Trieu-Cuot P

更新日期：2005-06-01 00:00:00

abstract：:Synthetic oligosaccharides derived from the capsular polysaccharide (PRP) of Haemophilus influenzae type b were conjugated to carrier proteins via a thioether linkage. Conjugates were made of trimeric and tetrameric ribose-ribitol-phosphate and tetanus toxoid or diphtheria toxin. All conjugates elicited anti-PRP antib...

journal_title：Infection and immunity

authors： Peeters CC,Evenberg D,Hoogerhout P,Käyhty H,Saarinen L,van Boeckel CA,van der Marel GA,van Boom JH,Poolman JT

更新日期：1992-05-01 00:00:00

abstract：:Peritoneal exudate cells from chickens immunized with two species of coccidia, Eimeria tenella or Eimeria maxima, were examined for their capacity to phagocytose stages of the parasite in vitro. True phagocytosis of the sporozoite stage is difficult to estimate because of its ability to invade cells, but may be evalua...

journal_title：Infection and immunity

authors： Rose ME

更新日期：1974-10-01 00:00:00

abstract：:Purified cell walls representing a wide variety in teichoic acid and peptidoglycan structure prepared from eight different gram-positive bacterial species induced the production of tumor necrosis factor alpha (TNF-alpha) and interleukin-6 from human monocytes in the presence of 10% plasma or serum. Significant amounts...

journal_title：Infection and immunity

authors： Heumann D,Barras C,Severin A,Glauser MP,Tomasz A

更新日期：1994-07-01 00:00:00

abstract：:AMA-1 of Plasmodium falciparum is a promising candidate antigen in malaria vaccine development. In this study, we have mapped the immunodominant T-cell determinants in this antigen by using synthetic peptides. From the amphipathic scores, 17 putative T-cell determinants were identified. Nine of the 17 peptides complem...

journal_title：Infection and immunity

authors： Lal AA,Hughes MA,Oliveira DA,Nelson C,Bloland PB,Oloo AJ,Hawley WE,Hightower AW,Nahlen BL,Udhayakumar V

更新日期：1996-03-01 00:00:00

abstract：:We characterized outer membrane proteins (OMPs) from selected Campylobacter jejuni, C. coli, and C. fetus strains by two-dimensional gel electrophoresis (2DGE), using isoelectric focusing and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and by immunoblotting with immune rabbit serum. The flage...

journal_title：Infection and immunity

authors： Dunn BE,Blaser MJ,Snyder EL

更新日期：1987-07-01 00:00:00

abstract：:Oral treponemes are considered to be important in the development and progression of periodontal diseases. We investigated the mechanisms of recognition and activation of human gingival epithelial cells (HGEC) with the oral treponemes Treponema denticola, Treponema vincentii, and Treponema medium and their outer membr...

journal_title：Infection and immunity

authors： Asai Y,Jinno T,Ogawa T

更新日期：2003-02-01 00:00:00

abstract：:Ninety-six Aeromonas hydrophila isolates were tested for cytotoxin and hemolysin production. Sixty-six (69%) of the isolates were both cytotoxic and hemolytic, whereas the rest produced neither cytotoxin nor hemolysin. No evidence of a separate cytotonic activity could be found in any of the isolates. Cytotoxin activi...

journal_title：Infection and immunity

authors： Cumberbatch N,Gurwith MJ,Langston C,Sack RB,Brunton JL

更新日期：1979-03-01 00:00:00

abstract：:Serological tests used in current brucellosis eradication schemes, such as bacterial tube agglutination, do not readily distinguish between infected animals and those immunized with strain 19 or 45/20 Brucella abortus vaccines. In this study, sera from naturally infected cattle were used to identify serologically impo...

journal_title：Infection and immunity

authors： Raybould TJ,Chantler S

更新日期：1980-08-01 00:00:00

abstract：:We report that hbhA is differentially regulated during Mycobacterium tuberculosis infection. Upregulation was observed in epithelial cell infection but not in macrophage infection and in the lungs but not in the spleens of infected mice, and it was greater during the early steps of infection, when bacilli disseminate ...

journal_title：Infection and immunity

authors： Delogu G,Sanguinetti M,Posteraro B,Rocca S,Zanetti S,Fadda G

更新日期：2006-05-01 00:00:00

abstract：:The mechanism by which hamsters acquire resistance to yaws or frambesia is poorly understood. This investigation has shown that immune lymphoid cells (spleen and lymph node) could confer on hamsters resistance to infection with Treponema pertenue. Treatment of these immune cells with a specific antithymocyte serum (AT...

journal_title：Infection and immunity

authors： Chan JK,Schell RF,LeFrock JL

更新日期：1979-07-01 00:00:00

abstract：:The infiltration of neutrophils which phagocytose and kill microorganisms is an important defense mechanism against infections of the airways. Bordetella pertussis is a human respiratory pathogen which colonizes ciliated epithelium, causing whooping cough. We have investigated the effects of the peptidoglycan fragment...

journal_title：Infection and immunity

authors： Cundell DR,Kanthakumar K,Taylor GW,Goldman WE,Flak T,Cole PJ,Wilson R

更新日期：1994-02-01 00:00:00

abstract：:The immunogenicity of a single dose of a whole-cell vaccine of inactivated Borrelia burgdorferi HSF (human spinal fluid isolate) was evaluated. Syrian hamsters were vaccinated subcutaneously and challenged by the intraperitoneal injection of 1,000 50% infectious doses of B. burgdorferi HSF 30 or 90 days postvaccinatio...

journal_title：Infection and immunity

authors： Johnson RC,Kodner C,Russell M

更新日期：1986-12-01 00:00:00

abstract：:Polymorphonuclear leukocytes (PMN) from patients with chronic granulomatous disease (CGD) fail to produce microbicidal concentrations of reactive oxygen species (ROS) due to mutations in NOX2. Patients with CGD suffer from severe, life-threatening infections and inflammatory complications. Granulibacter bethesdensis i...

journal_title：Infection and immunity

authors： Greenberg DE,Sturdevant DE,Marshall-Batty KR,Chu J,Pettinato AM,Virtaneva K,Lane J,Geller BL,Porcella SF,Gallin JI,Holland SM,Zarember KA

更新日期：2015-11-01 00:00:00

abstract：:Interleukin-10 (IL-10) is associated with inhibition of cell-mediated immunity and downregulation of the expression of costimulatory molecules required for T-cell activation. When IL-10-deficient (IL-10KO) mice are infected with Toxoplasma gondii, they succumb to a T-cell-mediated shock-like reaction characterized by ...

journal_title：Infection and immunity

authors： Villegas EN,Wille U,Craig L,Linsley PS,Rennick DM,Peach R,Hunter CA

更新日期：2000-05-01 00:00:00

abstract：:Since secondary Streptococcus pneumoniae infections greatly increase the mortality of influenza infections, we determined the relative roles of neutrophil-dependent and -independent mechanisms in increased susceptibility to S. pneumoniae during influenza infection. Mice infected with influenza for 6 days, but not 3 da...

journal_title：Infection and immunity

authors： McNamee LA,Harmsen AG

更新日期：2006-12-01 00:00:00

abstract：:Legionella pneumophila and Coxiella burnetii are phylogenetically related intracellular bacteria that cause aerosol-transmitted lung infections. In host cells both pathogens proliferate in vacuoles whose biogenesis displays some common features. To test the functional similarity of their respective intracellular niche...

journal_title：Infection and immunity

authors： Sauer JD,Shannon JG,Howe D,Hayes SF,Swanson MS,Heinzen RA

更新日期：2005-08-01 00:00:00

abstract：:A nonclonal population of Borrelia burgdorferi N40 (passage 3) that survived protective immunity following challenge inoculation of outer surface protein (Osp) A- or B-hyperimmunized mice were characterized for the molecular basis of evasion of immunity. Two of six B. burgdorferi isolates, cultured from OspA-immunized...

journal_title：Infection and immunity

authors： Fikrig E,Tao H,Barthold SW,Flavell RA

更新日期：1995-05-01 00:00:00

abstract：:The pathogenesis of middle ear inflammation caused by Streptococcus pneumoniae was explored in the chinchilla model with different pneumococcal cell wall (CW) preparations, including isolated native CW, M1 muramidase CW (M1-CW) digest, amidase CW digest, and M1 peptidoglycan (M1-PG) digest. Inflammatory cell and lysoz...

journal_title：Infection and immunity

authors： Carlsen BD,Kawana M,Kawana C,Tomasz A,Giebink GS

更新日期：1992-07-01 00:00:00

abstract：:Streptococcus pneumoniae is a fermentative microorganism and causes serious diseases in humans, including otitis media, bacteremia, meningitis, and pneumonia. However, the mechanisms enabling pneumococcal survival in the host and causing disease in different tissues are incompletely understood. The available evidence ...

journal_title：Infection and immunity

authors： Gaspar P,Al-Bayati FA,Andrew PW,Neves AR,Yesilkaya H

更新日期：2014-12-01 00:00:00

abstract：:Numerous studies have reported that asialo-GM(1), gangliotetraosylceramide, or moieties serve as epithelial cell receptors for Pseudomonas aeruginosa. Usually this interaction is confirmed with antibodies to asialo-GM(1). However, few, if any, of these reports have evaluated the binding of fresh clinical isolates of P...

journal_title：Infection and immunity

authors： Schroeder TH,Zaidi T,Pier GB

更新日期：2001-02-01 00:00:00

abstract：:A novel immunobiologically active fraction was prepared from a phenol-water extract of Prevotella intermedia ATCC 25611 by Sephadex G-100 column chromatography. The fraction consisted mainly of carbohydrate and protein and was devoid of fatty acid. The fraction showed high-molecular-weight bands (10,000 to 12,000) on ...

journal_title：Infection and immunity

authors： Iki K,Kawahara K,Sawamura S,Arakaki R,Sakuta T,Sugiyama A,Tamura H,Sueda T,Hamada S,Takada H

更新日期：1997-11-01 00:00:00