Role of the bacterial cell wall in middle ear inflammation caused by Streptococcus pneumoniae.

abstract：:Borrelia burgdorferi, the bacterium that causes Lyme disease, has a unique segmented genome consisting of numerous linear and circular plasmids and a linear chromosome. Many of these genetic elements have been found to encode factors critical for B. burgdorferi to complete the infectious cycle. However, several plasmi...

journal_title：Infection and immunity

authors： Dulebohn DP,Bestor A,Rosa PA

更新日期：2013-08-01 00:00:00

abstract：:Vibrio parahaemolyticus is the leading cause of bacterial seafood-borne gastroenteritis worldwide, yet little is known about how this pathogen colonizes the human intestine. The alternative sigma factor RpoN/sigma-54 is a global regulator that controls flagellar synthesis, as well as a wide range of nonflagellar genes...

journal_title：Infection and immunity

authors： Whitaker WB,Richards GP,Boyd EF

更新日期：2014-02-01 00:00:00

abstract：:An array of pro- and anti-inflammatory mediators of the innate immune system was analyzed in stool, urine, and rectal mucosa samples from adults and children with shigellosis to better understand their role in recovery from and in the immunopathogenesis of the disease. Increased concentrations of lactoferrin (Lf), mye...

journal_title：Infection and immunity

authors： Raqib R,Mia SM,Qadri F,Alam TI,Alam NH,Chowdhury AK,Mathan MM,Andersson J

更新日期：2000-06-01 00:00:00

abstract：:Hamster trachea organ cultres were shown to consume measurable amounts of oxygen when incubated in a closed micro-chamber. Several simple and complex media were evaluated, and the optimal system involved incubating 2 to 4 mg of tracheal tissue in Tyrodes balanced salt solution at 37 C for 60 min, with oxygen activity ...

journal_title：Infection and immunity

authors： Gabridge MG

更新日期：1975-09-01 00:00:00

abstract：:Cryptococcus neoformans is an opportunistic fungal pathogen that primarily causes disease in immunocompromised individuals. Dendritic cells (DCs) can phagocytose C. neoformans, present cryptococcal antigen, and kill C. neoformans. However, early events following C. neoformans phagocytosis by DCs are not well defined. ...

journal_title：Infection and immunity

authors： Wozniak KL,Levitz SM

更新日期：2008-10-01 00:00:00

abstract：:Polymicrobial intra-abdominal infections (IAI) are clinically prevalent and cause significant morbidity and mortality, especially those involving fungi. Our laboratory developed a mouse model of polymicrobial IAI and demonstrated that coinfection with Candida albicans and Staphylococcus aureus (C. albicans/S. aureus) ...

journal_title：Infection and immunity

authors： Lilly EA,Yano J,Esher SK,Hardie E,Fidel PL Jr,Noverr MC

更新日期：2019-07-23 00:00:00

abstract：:Neonatal piglets have been used as models to study human campylobacteriosis and helicobacteriosis. The purpose of this study was to determine the relative pathogenicities, on the basis of the duration of fecal shedding and colonization of tissues, of three Arcobacter species in 1-day-old cesarean-derived colostrum-dep...

journal_title：Infection and immunity

authors： Wesley IV,Baetz AL,Larson DJ

更新日期：1996-06-01 00:00:00

abstract：:Haemophilus ducreyi expresses 2 OmpA homologs, designated MOMP and OmpA2, whose genes are arranged in tandem on the chromosome. Northern blot analysis indicated that momp and ompA2 are transcribed independently. Sequences of the momp open reading frame (ORF) lacking the transcriptional start site were amplified by PCR...

journal_title：Infection and immunity

authors： Throm RE,Al-Tawfiq JA,Fortney KR,Katz BP,Hood AF,Slaughter CA,Hansen EJ,Spinola SM

更新日期：2000-05-01 00:00:00

abstract：:Previously, in our laboratory, we established a two-chamber system to study translocation of Enterococcus faecalis across monolayers of polarized human colon carcinoma-derived T84 cells. By using the same system in the present study, we now show that disruption of gelE of strain OG1RF, which also has a polar effect on...

journal_title：Infection and immunity

authors： Zeng J,Teng F,Murray BE

更新日期：2005-03-01 00:00:00

abstract：:To identify potential vaccine candidates for the prevention of infection with the filarial nematode Onchocerca volvulus, we screened an O. volvulus L3 stage cDNA library with sera from putatively immune (PI) subjects, and a prominent immunogenic clone of 1,184 nucleotides was identified. It contained an open reading f...

journal_title：Infection and immunity

authors： McCarthy JS,Wieseman M,Tropea J,Kaslow D,Abraham D,Lustigman S,Tuan R,Guderian RH,Nutman TB

更新日期：2002-02-01 00:00:00

abstract：:The comparative immunogenicity of the two cross-reacting group 6 pneumococcal capsular polysaccharides, type 6A(6) and type 6B(26), was studied with hyperimmune rabbit typing antisera and with sera from adult volunteers injected with polyvalent pneumococcal vaccines containing either 50 mug of type 6A (U.S. designatio...

journal_title：Infection and immunity

authors： Robbins JB,Lee CJ,Rastogi SC,Schiffman G,Henrichsen J

更新日期：1979-12-01 00:00:00

abstract：:Henle 407 and HeLa cells were compared as hosts for Shigella dysenteriae at a low multiplicity of infection. Efficiency of attachment and invasion without centrifugation, as well as selectivity for pathogenic over nonpathogenic S. dysenteriae without Congo red, were much greater for Henle 407 cells than for HeLa cells...

journal_title：Infection and immunity

authors： Sen A,Leon MA,Palchaudhuri S

更新日期：1990-07-01 00:00:00

abstract：:Human gamma delta T cells are known to respond at high frequencies to pathogenic mycobacteria. Here we show that opportunistic strains of mycobacteria share with pathogenic mycobacteria the ability to trigger at high frequencies human V gamma 9V delta 2 T-cell-receptor-positive T lymphocytes. Stimulating ligands were ...

journal_title：Infection and immunity

authors： Häcker G,Kromer S,Heeg K,Ivanyi J,Wagner H,Pfeffer K

更新日期：1992-07-01 00:00:00

abstract：:Intestinal segmented filamentous bacteria (SFB) protect from ameba infection, and protection is transferable with bone marrow dendritic cells (BMDCs). SFB cause an increase in serum amyloid A (SAA), suggesting that SAA might mediate SFB's effects on BMDCs. Here we further explored the role of bone marrow in SFB-mediat...

journal_title：Infection and immunity

authors： Burgess SL,Saleh M,Cowardin CA,Buonomo E,Noor Z,Watanabe K,Abhyankar M,Lajoie S,Wills-Karp M,Petri WA Jr

更新日期：2016-09-19 00:00:00

abstract：:The antigenic cross-reactivity between Treponema pallidum and several pathogenic members of the family Spirochaetaceae was examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting techniques. Blots of T. pallidum antigens were incubated with antiserum from rabbits infected or immunize...

journal_title：Infection and immunity

authors： Baker-Zander SA,Lukehart SA

更新日期：1984-10-01 00:00:00

abstract：:In studies of immunity to malaria, the absence of febrile malaria is commonly considered evidence of "protection." However, apparent "protection" may be due to a lack of exposure to infective mosquito bites or due to immunity. We studied a cohort that was given curative antimalarials before monitoring began and docume...

journal_title：Infection and immunity

authors： Bejon P,Warimwe G,Mackintosh CL,Mackinnon MJ,Kinyanjui SM,Musyoki JN,Bull PC,Marsh K

更新日期：2009-05-01 00:00:00

abstract：:Whole cells, morphological components, and various extracts of Candida albicans were tested for toxicity by methods involving biological activities ordinarily used to characterize bacterial endotoxin. Fungal preparations exerted several of these activities, but only at much higher dose levels than those required for b...

journal_title：Infection and immunity

authors： Cutler JE,Friedman L,Milner KC

更新日期：1972-10-01 00:00:00

abstract：:In this communication, we examine the specificity of anti-herpes simplex virus (HSV) cytotoxic T lymphocytes (CTL). Serological studies of the two related HSV serotypes (HSV-1 and HSV-2) have revealed both type-specific and cross-reactive antigenic determinants in the viral envelope and on the surface of infected cell...

journal_title：Infection and immunity

authors： Eberle R,Russell RG,Rouse BT

更新日期：1981-12-01 00:00:00

abstract：:Our previous work suggests that one mechanism through which connective tissue breakdown might occur in periodontal diseases is the production of metalloproteinases, including collagenase, by gingival fibroblasts. In this study we investigated whether highly purified preparations of lipopolysaccharide (LPS) and lipotei...

journal_title：Infection and immunity

authors： Heath JK,Atkinson SJ,Hembry RM,Reynolds JJ,Meikle MC

更新日期：1987-09-01 00:00:00

abstract：:Avian pathogenic Escherichia coli (APEC) cause extraintestinal disease in avian species via respiratory tract infection. Virulence factors associated with APEC include type 1 and P fimbriae, curli, aerobactin, lipopolysaccharide (LPS), K1 capsular antigen, temperature-sensitive hemagglutinin (Tsh), and an uncharacteri...

journal_title：Infection and immunity

authors： Mellata M,Dho-Moulin M,Dozois CM,Curtiss R 3rd,Lehoux B,Fairbrother JM

更新日期：2003-01-01 00:00:00

abstract：:Polymorphonuclear leukocytes from 46 adults (age 18 to 35), 19 adults (age 70 to 91), 10 children (age 1 to 3), and 22 neonates (cord blood samples) were tested for their chemiluminescence response to opsonized zymosan. Results indicated that both cord blood leukocytes and those from individuals over 70 were significa...

journal_title：Infection and immunity

authors： Van Epps DE,Goodwin JS,Murphy S

更新日期：1978-10-01 00:00:00

abstract：:Alpha-toxin, the major cytolysin of Staphylococcus aureus, preferentially attacks human platelets and cultured monocytes, thereby promoting coagulation and the release of interleukin-1 and tumor necrosis factor. Titers of naturally occurring antibodies in human blood are not high enough to substantially inhibit these ...

journal_title：Infection and immunity

authors： Bhakdi S,Mannhardt U,Muhly M,Hugo F,Ronneberger H,Hungerer KD

更新日期：1989-10-01 00:00:00

abstract：:Antibodies against the Plasmodium falciparum P0 ribosomal phosphoprotein (PfP0) have been detected exclusively but extensively in malaria-immune persons. Polyclonal rabbit and mice sera were raised against two recombinant polypeptides of P. falciparum P0 protein, PfP0N and PfP0C, covering amino acids 17 to 61 and the ...

journal_title：Infection and immunity

authors： Chatterjee S,Singh S,Sohoni R,Singh NJ,Vaidya A,Long C,Sharma S

更新日期：2000-07-01 00:00:00

abstract：:The role of CD8 T cells in controlling Mycobacterium tuberculosis infections in mice was confirmed by comparing the levels of growth of the organism in control, major histocompatibility complex class II knockout, and athymic mice and by transferring T-cell populations into athymic mice. By using donor mice which were ...

journal_title：Infection and immunity

authors： Tascon RE,Stavropoulos E,Lukacs KV,Colston MJ

更新日期：1998-02-01 00:00:00

abstract：:Salmonella enterica serovars Typhimurium and Dublin lysed primary bovine alveolar macrophages and immortalized J774.2 macrophage-like cells in the absence of either the morphological changes or DNA fragmentation characteristic of apoptosis. Macrophage lysis was dependent on a subset of caspases and an intact sipB gene...

journal_title：Infection and immunity

authors： Watson PR,Gautier AV,Paulin SM,Bland AP,Jones PW,Wallis TS

更新日期：2000-06-01 00:00:00

abstract：:The bactericidal and opsonizing effects of normal human serum on six strains of Salmonella typhimurium LT-2 having different lipopolysaccharide (LPS) composition were demonstrated through five indices. Complement activity in the presence of antibody was important for the opsonization of all six strains and for the bac...

journal_title：Infection and immunity

authors： Shaio MF,Rowland H

更新日期：1985-09-01 00:00:00

abstract：:Commercial fluid used for peritoneal lavage in peritonitis and in peritoneal dialysis suppressed the activity of peripheral blood leukocytes as measured by chemiluminescence, phagocytosis, and bacterial killing. Suppression was found to be due to the low pH and high osmolality of the fluid. The pH was adjusted to noni...

journal_title：Infection and immunity

authors： Duwe AK,Vas SI,Weatherhead JW

更新日期：1981-07-01 00:00:00

abstract：:Previous studies in our laboratory have indicated that naturally resistant, inbred DBA/2J mice mount a greater serum antibody response to Pseudomonas aeruginosa 19660 than susceptible C57BL/6J mice. However, the specificity of the antibody produced was not known. The present study examines the specificity and kinetics...

journal_title：Infection and immunity

authors： Preston MJ,Berk JM,Hazlett LD,Berk RS

更新日期：1991-06-01 00:00:00

abstract：:Streptococcus pneumoniae sortase A (SrtA) is a transpeptidase that is highly conserved among pneumococcal strains, whose involvement in adhesion/colonization has been reported. We found that intraperitoneal immunization with recombinant SrtA conferred to mice protection against S. pneumoniae intraperitoneal challenge ...

journal_title：Infection and immunity

authors： Gianfaldoni C,Maccari S,Pancotto L,Rossi G,Hilleringmann M,Pansegrau W,Sinisi A,Moschioni M,Masignani V,Rappuoli R,Del Giudice G,Ruggiero P

更新日期：2009-07-01 00:00:00

abstract：:Staphylococcal alpha-toxin was purified from Staphylococcus aureus growth medium using adsorption chromatography on controlled pore glass beads. Elution of alpha-toxin from the unmodified glass surface of the beads with various anions generally followed the chaotropic series. Alpha-toxin, purified by glass bead chroma...

journal_title：Infection and immunity

authors： Cassidy P,Harshman S

更新日期：1976-03-01 00:00:00