Allele specificity of naturally acquired antibody responses against Plasmodium falciparum apical membrane antigen 1.

abstract：:Peptide 9 (TDAYNQKLSERRAN) and peptide 10 (NATAEGRAINRRVE) represent surface-exposed epitopes of outer membrane protein F of Pseudomonas aeruginosa. Rats immunized with four intramuscular inoculations on days 0, 14, 28, and 42 with either peptide 9 or peptide 10 conjugated to keyhole limpet hemocyanin were afforded pr...

journal_title：Infection and immunity

authors： Gilleland LB,Gilleland HE Jr

更新日期：1995-06-01 00:00:00

abstract：:The gastric spirillum Helicobacter felis, originally isolated from the cat stomach, colonizes the stomachs of germfree rats. Studies were designed to examine the pathological and serological responses of germfree rats inoculated orally with H. felis. At 2 weeks postinoculation, the gastric mucosa of germfree rats had ...

journal_title：Infection and immunity

authors： Fox JG,Lee A,Otto G,Taylor NS,Murphy JC

更新日期：1991-03-01 00:00:00

abstract：:A recent study found that group A Streptococcus (GAS) expresses a cell surface protein with similarity to human collagen (S. Lukomski, K. Nakashima, I. Abdi, V. J. Cipriano, R. M. Ireland, S. R. Reid, G. G. Adams, and J. M. Musser, Infect. Immun. 68:6542-6553, 2000). This streptococcal collagen-like protein (Scl) cont...

journal_title：Infection and immunity

authors： Lukomski S,Nakashima K,Abdi I,Cipriano VJ,Shelvin BJ,Graviss EA,Musser JM

更新日期：2001-03-01 00:00:00

abstract：:Toxicity of lipopolysaccharide (LPS) (endotoxin) is, to a large extent, mediated by the activation of monocytes/macrophages and subsequent release of monokines, such as interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-alpha). It is known that LPS binds readily to serum lipoproteins and that LPS-lipoprotein co...

journal_title：Infection and immunity

authors： Flegel WA,Wölpl A,Männel DN,Northoff H

更新日期：1989-07-01 00:00:00

abstract：:We examined the intracellular growth of 20 strains within six species of Legionella in thioglycolate-elicited peritoneal macrophages from A/J and C57BL/6 mice and a congenic strain derived from them (A.B Lgn1). With the exception of Legionella pneumophila Togus-1 and Bloomington-2, the intracellular growth of the 15 L...

journal_title：Infection and immunity

authors： Miyamoto H,Maruta K,Ogawa M,Beckers MC,Gros P,Yoshida S

更新日期：1996-05-01 00:00:00

abstract：:A cytotoxin was found in culture filtrates of a number of Escherichia coli strains that differed from the known heat-stable and heat-labile enterotoxins of E. coli. It was cytotoxic for Vero but not for Y-1 or CHO cells, and its effect on Vero was distinctly different from that of heat-labile enterotoxin. It was labil...

journal_title：Infection and immunity

authors： Konowalchuk J,Speirs JI,Stavric S

更新日期：1977-12-01 00:00:00

abstract：:The pathogenesis of Staphylococcus aureus infections is influenced by multiple virulence factors that are expressed under variable conditions, and this has complicated the design of an effective vaccine. Clinical trials that targeted the capsule or clumping factor A (ClfA) failed to protect the recipients against stap...

journal_title：Infection and immunity

authors： Tuchscherr LP,Buzzola FR,Alvarez LP,Lee JC,Sordelli DO

更新日期：2008-12-01 00:00:00

abstract：:Relapsing fever (RF) is a spirochetal infection characterized by periods of sickness with fever at time of high bacteremia that alternate with afebrile periods of relative well being during low bacteremia. Patients with epidemic RF who are doing relatively well have extraordinarily high levels of interleukin-10 (IL-10...

journal_title：Infection and immunity

authors： Londoño D,Marques A,Hornung RL,Cadavid D

更新日期：2008-12-01 00:00:00

abstract：:Surface proteins in gram-positive bacteria are frequently required for virulence, and many are attached to the cell wall by sortase enzymes. Bacteria frequently encode more than one sortase enzyme and an even larger number of potential sortase substrates that possess an LPXTG-type cell wall sorting signal. In order to...

journal_title：Infection and immunity

authors： Comfort D,Clubb RT

更新日期：2004-05-01 00:00:00

abstract：:Evidence that the bactericidal ability and the stimulated oxidative metabolism of leukocytes appear in parallel during fetal development of the Minnesota Miniature pig has been obtained by application of the techniques applied to studies of human cells. It was demonstrated that leukocytes from 87- to 90-day fetuses we...

journal_title：Infection and immunity

authors： Holmes B,Day N,Haseman J,Good RA

更新日期：1972-02-01 00:00:00

abstract：:We investigated the ability of two overlapping fragments of staphylococcal enterotoxin B (SEB), which encompass the whole toxin, to induce protection and also examined if passive transfer of chicken anti-SEB antibodies raised against the holotoxin could protect rhesus monkeys against aerosolized SEB. Although both fra...

journal_title：Infection and immunity

authors： LeClaire RD,Hunt RE,Bavari S

更新日期：2002-05-01 00:00:00

abstract：:A number of polymorphonuclear leukocyte (PMN) chemotactic factors derived from complement components have been described. We sought to determine which of these factors accounted for the majority of PMN chemotactic activity in rabbit serum and guinea pig serum treated with preformed immune complexes. Normal rabbit sera...

journal_title：Infection and immunity

authors： Snyderman R,Phillips J,Mergenhagen SE

更新日期：1970-06-01 00:00:00

abstract：:Genetic defects in the Rab27a or Munc13-4 gene lead to immunodeficiencies in humans, characterized by frequent viral and bacterial infections. However, the role of Rab27a and Munc13-4 in the regulation of systemic inflammation initiated by Gram-negative bacterium-derived pathogenic molecules is currently unknown. Usin...

journal_title：Infection and immunity

authors： Johnson JL,Hong H,Monfregola J,Catz SD

更新日期：2011-09-01 00:00:00

abstract：:The presence of soybean meal in the diet of gnotobiotic mice was shown to prevent the establishment of a clostridial strain in the gastrointestinal tract. Soybean meal did not inhibit the growth of Clostridium in vitro, suggesting that the host plays a role in the observed inhibition of bacterial growth. The inhibitor...

journal_title：Infection and immunity

authors： Lhuillery C,Demarne Y,Ducluzeau R,Clara A

更新日期：1982-05-01 00:00:00

abstract：:Previous studies have reported that human vascular endothelial cells lack the membrane-bound lipopolysaccharide (LPS) receptor, CD14 (mCD14). By optimizing assay conditions, including the selection of anti-CD14 monoclonal antibody, we now demonstrate that human umbilical vein endothelial cells (HUVEC) express CD14 on ...

journal_title：Infection and immunity

authors： Jersmann HP,Hii CS,Hodge GL,Ferrante A

更新日期：2001-01-01 00:00:00

abstract：:A water-soluble acylpolygalactosyl (APG) of 34 kDa was obtained from the Klebsiella pneumoniae membrane by alkaline hydrolysis and delipidation. APG comprises a poly(1,3)galactose chain, a core, and a lipid moiety made of a glucosamine disaccharide with two N-linked beta OH-myristates. The monocyte binding sites for A...

journal_title：Infection and immunity

authors： Hmama Z,Mey A,Normier G,Binz H,Revillard JP

更新日期：1994-05-01 00:00:00

abstract：:A protein factor which induces high levels of gamma interferon (IFN-gamma) in resting splenic nonadherent cells was isolated from the sera of mice with generalized inflammation caused by endotoxic shock. The factor was highly purified by ammonium sulfate precipitation followed by ion-exchange column chromatography on ...

journal_title：Infection and immunity

authors： Nakamura K,Okamura H,Nagata K,Komatsu T,Tamura T

更新日期：1993-01-01 00:00:00

abstract：:To study responses to Mycobacterium leprae antigens, we developed an in vitro model system in which latex particles coated with M. leprae sonic extract (MLSON) antigen were presented to monocytes. Uptake and oxidative response as measured by superoxide production to these antigens were investigated. Phagocytosis of ML...

journal_title：Infection and immunity

authors： Hasan RS,Dockrell HM,Jamil S,Chiang TJ,Hussain R

更新日期：1993-09-01 00:00:00

abstract：:In order to determine the carrier nature of lipopolysaccharide from Brucella abortus (LPS-BA) in evoking humoral responses, normal and immunodeficient mice were immunized with trinitrophenyl (TNP)-conjugated LPS-BA (TNP-LPS-BA) and the responses were compared with those to known T-dependent and T-independent antigens....

journal_title：Infection and immunity

authors： Betts M,Beining P,Brunswick M,Inman J,Angus RD,Hoffman T,Golding B

更新日期：1993-05-01 00:00:00

abstract：:Lipopolysaccharide (LPS) is cleared from the blood mainly by the liver. The Kupffer cells are primarily responsible for this clearance; liver endothelial and parenchymal cells contribute to a lesser extent. Although several binding sites have been described, only CD14 is known to be involved in LPS signalling. Among t...

journal_title：Infection and immunity

authors： van Oosten M,van de Bilt E,van Berkel TJ,Kuiper J

更新日期：1998-11-01 00:00:00

abstract：:A veronal buffer extract of Salmonella typhi was used as the reference antigen and its corresponding rabbit antiserum as the reference antibody in crossed immunoelectrophoresis to analyze antibodies in sera obtained from typhoid patients and carriers. Four precipitating antibodies were regularly detected. Three were a...

journal_title：Infection and immunity

authors： Chau PY,Wan KC,Tsang RS

更新日期：1984-03-01 00:00:00

abstract：:During persistence of nonencapsulated Haemophilus influenzae in the respiratory tracts of patients with chronic bronchitis, the major outer membrane proteins (MOMPs) P2 and P5 show antigenic drift. The hypothesis that appearance of antigenic variants is the consequence of antibody-dependent selection was tested in a r...

journal_title：Infection and immunity

authors： Vogel L,Duim B,Geluk F,Eijk P,Jansen H,Dankert J,vanAlphen L

更新日期：1996-03-01 00:00:00

abstract：:Escherichia coli O45 isolates associated with swine postweaning diarrhea in Québec were characterized with respect to virulence determinants genetically and investigated for their attaching and effacing (A/E) activities by experimental inoculation of gnotobiotic piglets and by the HEp-2 cell adherence assay. All of 32...

journal_title：Infection and immunity

authors： Zhu C,Harel J,Jacques M,Desautels C,Donnenberg MS,Beaudry M,Fairbrother JM

更新日期：1994-10-01 00:00:00

abstract：:An antigenic complex has been isolated in a highly purified from from the Melvin strain of Neisseria gonorrhoeae. The complex has a molecular weight of 9.3 x 10(6) and on sodium dodecyl sulfate-polyacrylamide gel electrophoresis was found to consist of several subunits; the most predominant had the following molecular...

journal_title：Infection and immunity

authors： Karkhanis YD,Anderson RL,Zeltner JY,Carlo DJ,Stoudt TH

更新日期：1979-08-01 00:00:00

abstract：:We have previously demonstrated the existence of Klebsiella pneumoniae clinical isolates deficient in the lipopolysaccharide O side chain, the major factor for resistance to complement-mediated killing in this bacterial species. These isolates are complement resistant, and their mechanisms to resist complement were in...

journal_title：Infection and immunity

authors： Alvarez D,Merino S,Tomás JM,Benedí VJ,Albertí S

更新日期：2000-02-01 00:00:00

abstract：:Salmonella enterica serovar Typhimurium causes self-limiting gastroenteritis in humans and a typhoid-like disease in mice that serves as a model for typhoid infections in humans. A critical step in Salmonella pathogenesis is the invasion of enterocytes and M cells of the small intestine via expression of a type III se...

journal_title：Infection and immunity

authors： Boddicker JD,Jones BD

更新日期：2004-04-01 00:00:00

abstract：:The mechanisms that govern the initial interaction between Paracoccidioides brasiliensis, a primary dimorphic fungal pathogen, and cells of the innate immunity need to be clarified. Our previous studies showed that Toll-like receptor 2 (TLR2) and TLR4 regulate the initial interaction of fungal cells with macrophages a...

journal_title：Infection and immunity

authors： Loures FV,Pina A,Felonato M,Feriotti C,de Araújo EF,Calich VL

更新日期：2011-06-01 00:00:00

abstract：:Intracellular bacterial infections affect all vertebrates. Cultured fish are particularly vulnerable because no effective protection measures have been established since such infections emerged approximately 50 years ago. As in other vertebrates, the induction of cell-mediated immunity (CMI) plays an important role in...

journal_title：Infection and immunity

authors： Matsumoto M,Kubota T,Fujita S,Shiozaki K,Kishida S,Yamamoto A

更新日期：2019-10-18 00:00:00

abstract：:An array of pro- and anti-inflammatory mediators of the innate immune system was analyzed in stool, urine, and rectal mucosa samples from adults and children with shigellosis to better understand their role in recovery from and in the immunopathogenesis of the disease. Increased concentrations of lactoferrin (Lf), mye...

journal_title：Infection and immunity

authors： Raqib R,Mia SM,Qadri F,Alam TI,Alam NH,Chowdhury AK,Mathan MM,Andersson J

更新日期：2000-06-01 00:00:00

abstract：:Recurrent urinary tract infections (UTIs) are a significant clinical problem for many women; however, host susceptibility factors have not been completely defined. The mouse model of induced UTI provides an experimental environment in which to identify specific host characteristics that are important in initial bacter...

journal_title：Infection and immunity

authors： Hopkins WJ,Gendron-Fitzpatrick A,Balish E,Uehling DT

更新日期：1998-06-01 00:00:00