Mutation of sarA in Staphylococcus aureus limits biofilm formation.

abstract：:We have previously shown that Bacillus anthracis lethal toxin represses glucocorticoid receptor (GR) transactivation. We now report that repression of GR activity also occurs with the large clostridial toxins produced by Clostridium sordellii and C. difficile. This was demonstrated using a transient transfection assay...

journal_title：Infection and immunity

authors： Tait AS,Dalton M,Geny B,D'Agnillo F,Popoff MR,Sternberg EM

更新日期：2007-08-01 00:00:00

abstract：:Neutralizing antibodies were raised in mice that had been inoculated repeatedly with moderate quantities of human leukocyte interferon highly purified by affinity chromatography on immobilized anti-interferon globulins. Interferon preparations of lesser purity sensitized the mice to subsequent inoculations of interfer...

journal_title：Infection and immunity

authors： Dalton BJ,Ogburn CA,Paucker K

更新日期：1978-02-01 00:00:00

abstract：:Schistosomiasis affects nearly 40 million women of reproductive age. Many of these women are infected while pregnant and lactating. Several studies have demonstrated transplacental trafficking of schistosome antigens; however, little is known regarding how these antigens affect the developing fetus and placenta. To ev...

journal_title：Infection and immunity

authors： McDonald EA,Kurtis JD,Acosta L,Gundogan F,Sharma S,Pond-Tor S,Wu HW,Friedman JF

更新日期：2013-03-01 00:00:00

abstract：:Streptococcal group A, B, and C carbohydrates were analyzed by counterimmunoelectrophoresis, immunoelectrophoresis, and inhibition of immunoprecipitation. Extracts of streptococci group A or C were shown by counterimmunoelectrophoresis to contain both anodic and cathodic migrating components. In immunoelectrophoresis,...

journal_title：Infection and immunity

authors： Fung JC,Wicher K,McCarty M

更新日期：1982-07-01 00:00:00

abstract：:Coxiella burnetii, phase I and II, cells cultivated in the yolk sac of chicken embryos were separated from host cell components by two cycles of isopycnic Renografin gradient centrifugation. Initial steps in the purification of viable C. burnetii involved differential centrifugation and sedimentation through an aqueou...

journal_title：Infection and immunity

authors： Williams JC,Peacock MG,McCaul TF

更新日期：1981-05-01 00:00:00

abstract：:Escherichia coli F-18, isolated from the feces of a healthy human in 1977, is an excellent colonizer of the streptomycin-treated mouse large intestine and displays normal motility and chemotaxis ability. A chemotaxis-defective derivative of E. coli F-18, E, coli F-18 CheA-, and a nonflagellated derivative, E. coli F-1...

journal_title：Infection and immunity

authors： McCormick BA,Laux DC,Cohen PS

更新日期：1990-09-01 00:00:00

abstract：:CD14, the leukocyte receptor for lipopolysaccharide (LPS), is important in the response of human polymorphonuclear leukocytes (PMNs) to infection with gram-negative bacteria. The level of CD14 on the PMN surface increases after exposure to some inflammatory stimuli such as N-formyl-methionyl-leucyl-phenylalanine (fMLP...

journal_title：Infection and immunity

authors： Rodeberg DA,Morris RE,Babcock GF

更新日期：1997-11-01 00:00:00

abstract：:Salmonella infection can cause gastroenteritis in healthy individuals or a serious, systemic infection in immunocompromised patients and has a global impact. CD4 Th1 cells represent the main lymphocyte population that participates in bacterial clearance during both primary and secondary infections in mice of the H-2b ...

journal_title：Infection and immunity

authors： Labuda JC,Depew CE,Pham OH,Benoun JM,Ramirez NA,McSorley SJ

更新日期：2019-10-18 00:00:00

abstract：:Cultured mammalian cells extend the time of survival of Treponema pallidum (Nichols strain). Various parameters that have been previously shown to enhance treponemal survival in vitro were examined for influences on the interaction of T. pallidum with cultured cells. With cells derived from normal rabbit testes, the t...

journal_title：Infection and immunity

authors： Fitzgerald TJ,Johnson RC,Sykes JA,Miller JN

更新日期：1977-02-01 00:00:00

abstract：:In a model of experimental Chagas' disease induced with metacyclic forms of Trypanosoma cruzi, CD4+ but not CD8+ T cells undergo T-cell receptor (TCR)-CD3-mediated activation-induced cell death (AICD) in vitro. CD4+ T cells from T. cruzi-infected mice also developed unresponsiveness in proliferative responses to TCR-C...

journal_title：Infection and immunity

authors： Lopes MF,DosReis GA

更新日期：1996-05-01 00:00:00

abstract：:A total of 224 strains were serogrouped by coagglutination (COA) and serotyped by protein I enzyme-linked immunosorbent assay (ELISA). Of these strains, 61 were from patients with disseminated gonococcal infection, 21 were from patients with pelvic inflammatory disease, and 115 were from patients with uncomplicated go...

journal_title：Infection and immunity

authors： Sandstrom EG,Knapp JS,Buchanan TB

更新日期：1982-01-01 00:00:00

abstract：:Using a murine respiratory infection model, we have demonstrated previously that infection with Bordetella pertussis or immunization with a whole-cell pertussis vaccine induced antigen-specific Th1 cells, which conferred a high level of protection against aerosol challenge. In contrast, immunization with an acellular ...

journal_title：Infection and immunity

authors： Mahon BP,Ryan MS,Griffin F,Mills KH

更新日期：1996-12-01 00:00:00

abstract：:Cultures of Serpulina pilosicoli 95/1000, isolated from a pig with porcine intestinal spirochetosis (PIS), and S. pilosicoli WesB, isolated from an Aboriginal child with diarrhea, were used to infect 5-week-old newly weaned pigs. Four of 12 pigs infected with strain 95/1000 and 2 of 12 pigs infected with strain WesB b...

journal_title：Infection and immunity

authors： Trott DJ,Huxtable CR,Hampson DJ

更新日期：1996-11-01 00:00:00

abstract：:A significant clinical complication of pulmonary infections with Klebsiella pneumoniae is peripheral blood dissemination, resulting in a systemic infection concurrent with the localized pulmonary infection. In this context, little is known about the role of tumor necrosis factor receptor 1 (TNFR1)-mediated innate immu...

journal_title：Infection and immunity

authors： Moore TA,Perry ML,Getsoian AG,Monteleon CL,Cogen AL,Standiford TJ

更新日期：2003-09-01 00:00:00

abstract：:Phagocytosis of unopsonized Salmonella typhimurium 395, MR-10, opsonized Salmonella typhimurium 395 MS, and Staphylococcus epidermidis by rabbit polymorphonuclear leukocytes was inhibited by heparin at concentrations as low as 0.5 U/ml. Inhibition was dose dependent and nearly complete at 20 U/ml. Provided that hepari...

journal_title：Infection and immunity

authors： Victor M,Weiss J,Elsbach P

更新日期：1981-04-01 00:00:00

abstract：:Brucella abortus and polyacrylic acid, two agents whose interferon-inducing capacity in the mouse has been well established, failed to stimulate circulating interferon production in rabbits, yet protected rabbits against local vaccinia virus infection. ...

journal_title：Infection and immunity

authors： De Clercq E,De Somer P

更新日期：1973-10-01 00:00:00

abstract：:Conventional dendritic cells (cDCs) are critical for protection against pulmonary infection with the opportunistic fungal pathogen Cryptococcus neoformans; however, the role of plasmacytoid dendritic cells (pDCs) is unknown. We show for the first time that murine pDCs have direct activity against C. neoformans via rea...

journal_title：Infection and immunity

authors： Hole CR,Leopold Wager CM,Mendiola AS,Wozniak KL,Campuzano A,Lin X,Wormley FL Jr

更新日期：2016-08-19 00:00:00

abstract：:Bile aspirated from chicken gall bladders was found to contain substances neutralizing Newcastle disease virus (NDV). Nonspecific factors were present in the bile, probably the bile acids, which caused a reduction in the infectivity of the virus. Specific anti-NDV activity was found in the bile of birds that had been ...

journal_title：Infection and immunity

authors： Lee JS,Hanson RP

更新日期：1975-04-01 00:00:00

abstract：:Naegleria fowleri produces fatal meningoencephalitis in humans and in experimentally infected laboratory animals. The course of the disease in mice is dependent upon the infecting dose of amoebae, route of inoculation, and prior exposure to Naegleria antigens. DUB/ICR mice were immunized by various routes and antigen ...

journal_title：Infection and immunity

authors： John DT,Weik RR,Adams AC

更新日期：1977-06-01 00:00:00

abstract：:Human immunodeficiency virus (HIV)-infected individuals are predisposed to recurrent oral candidiasis, and, although it has been assumed that this is because of deficient mucosal immune responses, this has not been properly established. The present study aimed to compare the concentrations and secretion rates of immun...

journal_title：Infection and immunity

authors： Coogan MM,Sweet SP,Challacombe SJ

更新日期：1994-03-01 00:00:00

abstract：:The purpose of this study was to determine the effects of human monocytes, macrophages, and polymorphonuclear neutrophils (PMN) on the fungal pathogen Blastomyces dermatitidis in vitro. Peripheral blood monocyte monolayers significantly inhibited the replication of a virulent strain (V) and an avirulent strain (AV) of...

journal_title：Infection and immunity

authors： Brummer E,Stevens DA

更新日期：1982-04-01 00:00:00

abstract：:Cytolethal distending toxins (CDT) constitute an emerging heterogeneous family of bacterial toxins whose common biological property is to inhibit the proliferation of cells in culture by blocking their cycle at G2/M phase. In this study, we investigated the molecular mechanisms underlying the block caused by CDT from ...

journal_title：Infection and immunity

authors： Comayras C,Tasca C,Pérès SY,Ducommun B,Oswald E,De Rycke J

更新日期：1997-12-01 00:00:00

abstract：:A number of studies have substantiated the pivotal role of innate defense mechanisms in protection against invasive aspergillosis. However, experiments demonstrating increased resistance to lethal intravenous (i.v.) infection with Aspergillus fumigatus conidia in cortisone-treated or untreated mice preinfected with a ...

journal_title：Infection and immunity

authors： de Repentigny L,Petitbois S,Boushira M,Michaliszyn E,Sénéchal S,Gendron N,Montplaisir S

更新日期：1993-09-01 00:00:00

abstract：:Mouse spleen cultures were infected with murine cytomegalovirus, either before or after separating the cells into various classes, and the growth of virus and production of infectious centers were measured in each cell class. The separation techniques, which were used in various combinations, comprised: adherence to p...

journal_title：Infection and immunity

authors： Loh L,Hudson JB

更新日期：1979-12-01 00:00:00

abstract：:Secretory immunoglobulin A (SIgA) antibodies directed against the O antigen of lipopolysaccharide (LPS) are the primary determinants of mucosal immunity to gram-negative enteric pathogens. However, the underlying mechanisms by which these antibodies interfere with bacterial colonization and invasion of intestinal epit...

journal_title：Infection and immunity

authors： Forbes SJ,Eschmann M,Mantis NJ

更新日期：2008-09-01 00:00:00

abstract：:The role of a plasmid in the virulence activity of an enteropathogenic Escherichia coli (EPEC) strain belonging to serotype 0111:NM was examined. EPEC strain B171, which is resistant to chloramphenicol, streptomycin, sulfathiazole, and tetracycline, harbors a 54-megadalton plasmid, pYR111, and exhibits localized adher...

journal_title：Infection and immunity

authors： Riley LW,Junio LN,Libaek LB,Schoolnik GK

更新日期：1987-09-01 00:00:00

abstract：:Sera from certain animal species contain a substance(s) which binds hepatitis B surface antigen. The hepatitis B binding substance found in animals is not antibody, but appears to be a glycoprotein which reacted with antigen-coated beads and produced a "false positive" test for antibody. This glycoprotein could be sel...

journal_title：Infection and immunity

authors： Millman I,McMichael JC

更新日期：1978-09-01 00:00:00

abstract：:The results of a test of endotoxic potency based upon the development of histamine hypersensitivity in mice were compared with the results obtained by testing the same materials for pyrogenicity in rabbits and lethality for chicken embryos (CELD50). The results of the histamine hypersensitization test (HHT) correlated...

journal_title：Infection and immunity

authors： Bergman RK,Milner KC,Munoz JJ

更新日期：1977-11-01 00:00:00

abstract：:Numerous investigations have shown that 70-kDa heat shock protein (Hsp70) homologs interact tightly with hydrophobic proteins and functionally assist proteins in membranous organelles and environments. One such protein is the Chlamydia trachomatis Hsp70 that is associated with isolated outer membrane complexes of infe...

journal_title：Infection and immunity

authors： Raulston JE,Davis CH,Paul TR,Hobbs JD,Wyrick PB

更新日期：2002-02-01 00:00:00

abstract：:The relationship between the selective abilities of bacteria to adhere and their predilections for colonizing different mammalian hosts was investigated by using bacteria indigenous to the tongue dorsum of humans and rats as models. Streptococcus salivarius and S. sanguis averaged 22.6 and 2.8%, respectively, of the c...

journal_title：Infection and immunity

authors： Gibbons RJ,Spinell DM,Skobe Z

更新日期：1976-01-01 00:00:00