Ex vivo desequestration of Plasmodium falciparum-infected erythrocytes from human placenta by chondroitin sulfate A.

abstract：:It is currently accepted that malaria-parasitized red blood cells (pRBC) are eliminated, like senescent erythrocytes, phagocytically by macrophages in the red pulp of the spleen. Here, however, we show that self-healing Plasmodium chabaudi malaria activates spleen closure in C57BL/6 mice. Confocal laser scanning micro...

journal_title：Infection and immunity

authors： Krücken J,Mehnert LI,Dkhil MA,El-Khadragy M,Benten WP,Mossmann H,Wunderlich F

更新日期：2005-10-01 00:00:00

abstract：:Unmethylated CpG dinucleotide motifs present in bacterial genomes or synthetic oligodeoxynucleotides (ODNs) serve as strong immunostimulatory agents in mice, monkeys and humans. We determined the adjuvant effect of murine CpG ODN 1826 on the immunogenicity and protective efficacy of the Saccharomyces cerevisiae-expres...

journal_title：Infection and immunity

authors： Kumar S,Jones TR,Oakley MS,Zheng H,Kuppusamy SP,Taye A,Krieg AM,Stowers AW,Kaslow DC,Hoffman SL

更新日期：2004-02-01 00:00:00

abstract：:Previous studies demonstrated that Mycoplasma arthritidis strain 158 acquired a high degree of virulence upon lysogenization with bacteriophage MAV1. In the present study, the association between MAV1 and virulence was reexamined by creating new lysogens of 158 and of a relatively avirulent mutant, strain 158-1. In th...

journal_title：Infection and immunity

authors： Clapper B,Tu AH,Simmons WL,Dybvig K

更新日期：2004-12-01 00:00:00

abstract：:A 75-kilodalton major protein (75K protein) was purified to homogeneity from the cell lysate fraction and the envelope of Bacteroides gingivalis 381. The 75K protein was originally present in the outer membrane or the outermost part of this organism as a large, stable complex with an apparent molecular weight of about...

journal_title：Infection and immunity

authors： Yoshimura F,Watanabe K,Takasawa T,Kawanami M,Kato H

更新日期：1989-11-01 00:00:00

abstract：:MtsABC is a Streptococcus pyogenes ABC transporter which was previously shown to be involved in iron and zinc accumulation. In this study, we showed that an mtsABC mutant has impaired growth, particularly in a metal-depleted medium and an aerobic environment. In metal-depleted medium, growth was restored by the additi...

journal_title：Infection and immunity

authors： Janulczyk R,Ricci S,Björck L

更新日期：2003-05-01 00:00:00

abstract：:Campylobacter jejuni is a microaerobic bacterium that produces an acute, self-limiting, watery or bloody diarrhea in humans. Little is known about how C. jejuni causes disease or even what specific capabilities it requires for survival in vivo. The enzyme, superoxide dismutase (SOD), which catalyzes the breakdown of s...

journal_title：Infection and immunity

authors： Pesci EC,Cottle DL,Pickett CL

更新日期：1994-07-01 00:00:00

abstract：:Helicobacter mustelae is a urease-rich bacterium associated with gastritis in ferrets. The ureases of H. mustelae and Helicobacter pylori, a bacterium implicated in human gastritis, share many characteristics. Helicobacter sp. ureases appear to be unique among bacterial enzymes in exhibiting submillimolar Km values an...

journal_title：Infection and immunity

authors： Dunn BE,Sung CC,Taylor NS,Fox JG

更新日期：1991-09-01 00:00:00

abstract：:The levels of protection found in vaccine studies of murine visceral leishmaniasis are significantly lower than for cutaneous leishmaniasis; whether this is due to the high-challenge murine model employed and/or is a consequence of differences required in tissue-specific local immune responses is not understood. Conse...

journal_title：Infection and immunity

authors： Ahmed S,Colmenares M,Soong L,Goldsmith-Pestana K,Munstermann L,Molina R,McMahon-Pratt D

更新日期：2003-01-01 00:00:00

abstract：:Salmonellae possess the ability to adhere to and invade macrophages and in so doing trigger a number of intracellular events that are associated with cellular activation. As an initial approach to defining the mechanisms by which invasive salmonellae alter macrophage function, we have explored the impact of Salmonella...

journal_title：Infection and immunity

authors： Mizel SB,Kucera LS,Richardson SH,Ciacci F,Iyer NP

更新日期：1995-05-01 00:00:00

abstract：:Pneumolysin (PLY), an important virulence factor of Streptococcus pneumoniae, is known to exert various effects on the host immune cells, including cytokine induction, in addition to its known cytolytic activity as a member of the thiol-activated cytolysins. It is of interest to determine whether cytolytic activity is...

journal_title：Infection and immunity

authors： Baba H,Kawamura I,Kohda C,Nomura T,Ito Y,Kimoto T,Watanabe I,Ichiyama S,Mitsuyama M

更新日期：2002-01-01 00:00:00

abstract：:Cultured L929 cells infected with Rickettsia prowazekii had a greatly increased rate of hydrolysis of fatty acid from the oleic acid-radiolabeled phospholipids of the host cell membranes. The incorporation of fatty acid into phospholipid in an infected cell was only moderately inhibited relative to a mock-infected cel...

journal_title：Infection and immunity

authors： Winkler HH,Daugherty RM

更新日期：1989-01-01 00:00:00

abstract：:Human gingival fibroblasts were exposed in culture to cell extracts of different black-pigmented Bacteroides species, and their growth was monitored by determining thymidine uptake and counting cells. Of the Bacteroides species tested (B. gingivalis, B. asaccharolyticus, and B. intermedius), B. gingivalis gave the ext...

journal_title：Infection and immunity

authors： Larjava H,Uitto VJ,Eerola E,Haapasalo M

更新日期：1987-01-01 00:00:00

abstract：:The invasion of red blood cells (RBCs) by Plasmodium falciparum is dependent on multiple molecular interactions between erythrocyte receptors and parasite ligands. Invasion studies using culture-adapted parasite strains have indicated significant receptor heterogeneity. It is not known whether this heterogeneity refle...

journal_title：Infection and immunity

authors： Lobo CA,de Frazao K,Rodriguez M,Reid M,Zalis M,Lustigman S

更新日期：2004-10-01 00:00:00

abstract：:Using microarray technology, we studied the early differential expression of 3,528 genes in human meningothelial cells in response to meningococcal challenge. Thirty-two genes were up-regulated, and four were down-regulated. Those up-regulated included the tumor necrosis factor alpha, interleukin-6 (IL-6), and IL-8 (b...

journal_title：Infection and immunity

authors： Wells DB,Tighe PJ,Wooldridge KG,Robinson K,Ala' Aldeen DA

更新日期：2001-04-01 00:00:00

abstract：:Various factors affecting the aggregation of Actinomyces naeslundii strain 12104 were studied. When the pH of glucose-supplemented growth medium fell below 5.5, the cells aggregated and formed microbial masses which tenaciously adhered to the culture vessels. When the organism was cultured in the same medium in the ab...

journal_title：Infection and immunity

authors： Miller CH,Palenik CJ,Stamper KE

更新日期：1978-09-01 00:00:00

abstract：:Human monocytic ehrlichiosis (HME) is caused by a tick-borne obligate intracellular pathogen of the order Rickettsiales. HME disease can range from mild to a fatal, toxic shock-like syndrome, yet the mechanisms regulating pathogenesis are not well understood. We define a central role for type I interferons (alpha inte...

journal_title：Infection and immunity

authors： Zhang Y,Thai V,McCabe A,Jones M,MacNamara KC

更新日期：2014-04-01 00:00:00

abstract：:Toll-like receptors (TLRs) are a group of highly conserved molecules that initiate the innate immune response to pathogens by recognizing structural motifs expressed by microbes. We have identified a novel TLR, TLR15, by bioinformatic analysis of the chicken genome, which is distinct from any known vertebrate TLR and ...

journal_title：Infection and immunity

authors： Higgs R,Cormican P,Cahalane S,Allan B,Lloyd AT,Meade K,James T,Lynn DJ,Babiuk LA,O'farrelly C

更新日期：2006-03-01 00:00:00

abstract：:The screening of several inbred strains of mice suggested that the capacity of their spleen cells to respond to the mitogenic effect of lipopolysaccharide (LPS) of gram-negative bacteria was correlated with their resistance to intraperitoneal infection with Salmonella typhimurium. An infection of LPS into mice caused ...

journal_title：Infection and immunity

authors： von Jeney N,Günther E,Jann K

更新日期：1977-01-01 00:00:00

abstract：:Sporothrix schenckii is a human pathogen that causes sporotrichosis, an important cutaneous mycosis with a worldwide distribution. It produces dark-brown conidia, which infect the host. We found that S. schenckii synthesizes melanin via the 1,8-dihydroxynaphthalene pentaketide pathway. Melanin biosynthesis in the wild...

journal_title：Infection and immunity

authors： Romero-Martinez R,Wheeler M,Guerrero-Plata A,Rico G,Torres-Guerrero H

更新日期：2000-06-01 00:00:00

abstract：:Most Campylobacter jejuni strains are sensitive and most Campylobacter fetus strains are resistant to the bactericidal activity in normal human serum. We purified lipopolysaccharides from Campylobacter strains to determine whether their composition and structure relate to serum susceptibility. The lipopolysaccharide o...

journal_title：Infection and immunity

authors： Perez Perez GI,Blaser MJ

更新日期：1985-02-01 00:00:00

abstract：:An improved enterocyte adhesion assay has been used to examine a collection of 44 strains of enterotoxigenic Escherichia coli (ETEC) for their ability to adhere to the brush border of isolated human duodenal enterocytes. Fourteen strains showed good adhesion; in each case the ability to adhere correlated with the prod...

journal_title：Infection and immunity

authors： Knutton S,Lloyd DR,Candy DC,McNeish AS

更新日期：1985-06-01 00:00:00

abstract：:A clone expressing a 58-kDa protein reactive with human convalescent-phase serum was isolated from a recombinant library of Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis. Sequencing identified two open reading frames, one encoding a 10.3-kDa polypeptide consisting of 94 amino acids and another encod...

journal_title：Infection and immunity

authors： Sumner JW,Sims KG,Jones DC,Anderson BE

更新日期：1993-08-01 00:00:00

abstract：:A number of polymorphonuclear leukocyte (PMN) chemotactic factors derived from complement components have been described. We sought to determine which of these factors accounted for the majority of PMN chemotactic activity in rabbit serum and guinea pig serum treated with preformed immune complexes. Normal rabbit sera...

journal_title：Infection and immunity

authors： Snyderman R,Phillips J,Mergenhagen SE

更新日期：1970-06-01 00:00:00

abstract：:Infection of CFW mice with Trichinella spiralis induced a state of relative unresponsiveness to passive cutaneous anaphylaxis (PCA) induced with hen egg albumin and its corresponding antibodies. The unresponsiveness was to PCA produced either with immunoglobulin G1 (IgG1) or IgE type of antibodies, but was more pronou...

journal_title：Infection and immunity

authors： Munoz JJ,Cole RL

更新日期：1977-01-01 00:00:00

abstract：:Three parameters of rotavirus infection, i.e., clinical disease, viral antigen in infected intestines, and infectious virus in feces, were assessed in infant mice nursed by mothers with or without preexisting rotavirus antibody. Diarrhea was the only consistent sign of clinical disease, and its course followed that of...

journal_title：Infection and immunity

authors： Little LM,Shadduck JA

更新日期：1982-11-01 00:00:00

abstract：:Metastatic infection after hematogenous dissemination of Candida species is presumably dependent on the fungus traversing the vascular endothelium. An in vitro model of the earliest events of metastatic Candida infection was developed with whole vascular strips. Freshly obtained porcine blood vessels were secured in a...

journal_title：Infection and immunity

authors： Klotz SA,Drutz DJ,Harrison JL,Huppert M

更新日期：1983-10-01 00:00:00

abstract：:An enzyme-linked immunosorbent assay was developed to detect rabbit immunoglobulin G antibodies against purified lipopolysaccharide of the rough Re mutant of Salmonella minnesota. The time necessary for each step was investigated, and this resulted in a test that could be completed in 1 working day. Serial dilutions o...

journal_title：Infection and immunity

authors： Bruins SC,Ingwer I,Zeckel ML,White AC

更新日期：1978-09-01 00:00:00

abstract：:The amino acid sequence of heat-stable enterotoxin produced by enterotoxigenic Escherichia coli 18D has been revised. Amino acids originally assigned to positions 11 and 18, i.e., Tyr and Asn, respectively, were found to occupy positions 18 and 11, respectively. Thus all heat-stable enterotoxins composed of 18 amino a...

journal_title：Infection and immunity

authors： Thompson MR,Giannella RA

更新日期：1985-03-01 00:00:00

abstract：:Kinetic, microscopic, and biochemical studies show that virulent Ti (tumor inducing)-plasmid-containing strains of Agrobacterium attach to normal tobacco and carrot tissue culture cells. Kinetic studies showed that virulent strains of A. tumefaciens attach to the plant tissue culture cells in increasing numbers during...

journal_title：Infection and immunity

authors： Matthysse AG,Wyman PM,Holmes KV

更新日期：1978-11-01 00:00:00

abstract：:Enterotoxigenic Escherichia coli (ETEC) is a major cause of traveler's diarrhea as well as of endemic diarrhea and stunting in children in developing areas. However, a small-mammal model has been badly needed to better understand and assess mechanisms, vaccines, and interventions. We report a murine model of ETEC diar...

journal_title：Infection and immunity

authors： Bolick DT,Medeiros PHQS,Ledwaba SE,Lima AAM,Nataro JP,Barry EM,Guerrant RL

更新日期：2018-06-21 00:00:00