Isoprinosine augmentation of phytohemagglutinin-induced lymphocyte proliferation.

abstract：:The tetraspanins are a superfamily of transmembrane proteins with diverse functions and can form extended microdomains within the plasma membrane in conjunction with partner proteins, which probably includes receptors for bacterial adhesins. Neisseria meningitidis, the causative agent of meningococcal disease, attache...

journal_title：Infection and immunity

authors： Green LR,Monk PN,Partridge LJ,Morris P,Gorringe AR,Read RC

更新日期：2011-06-01 00:00:00

abstract：:The attachment and invasion of chicken ovarian granulosa cells by Salmonella enteritidis was examined in vitro. The attachment was inhibited by preincubation of granulosa cells with anti-chicken fibronectin antibody (approximately 70% reduction in attachment) or preincubation with a 14-kDa fimbrial protein isolated fr...

journal_title：Infection and immunity

authors： Thiagarajan D,Saeed M,Turek J,Asem E

更新日期：1996-12-01 00:00:00

abstract：:Cultured mammalian cells extend the time of survival of Treponema pallidum (Nichols strain). Various parameters that have been previously shown to enhance treponemal survival in vitro were examined for influences on the interaction of T. pallidum with cultured cells. With cells derived from normal rabbit testes, the t...

journal_title：Infection and immunity

authors： Fitzgerald TJ,Johnson RC,Sykes JA,Miller JN

更新日期：1977-02-01 00:00:00

abstract：:The two enteropathogens Yersinia pseudotuberculosis and Yersinia enterocolitica penetrate eukaryotic cells in vitro through invasin, a surface-exposed protein. In contrast, Yersinia pestis, the causative agent of plague, is unable to enter mammalian cell lines, although the inv gene is present on its chromosome. Altho...

journal_title：Infection and immunity

authors： Simonet M,Riot B,Fortineau N,Berche P

更新日期：1996-01-01 00:00:00

abstract：:Mice were infected with Chlamydia trachomatis (L2/434) and at various intervals after infection their lymphoid cells were tested directly for cytotoxic activity against Chlamydia-infected L929 cells. In a modified cell-mediated lympholysis assay, splenic, lymph node, and peritoneal exudate cells did not significantly ...

journal_title：Infection and immunity

authors： Pavia CS,Schachter J

更新日期：1983-03-01 00:00:00

abstract：:Acute lethality was induced in rabbits by the sequential injection of Propionibacterium acnes and lipopolysaccharide (LPS). P. acnes induced the infiltration of inflammatory cells into the liver lobules during the early phase, and LPS in the late phase caused death in association with pathological changes mimicking he...

journal_title：Infection and immunity

authors： Ikeda N,Mukaida N,Kaneko S,Fujioka N,Su S,Nariuchi H,Unoura M,Harada K,Nakanuma Y,Kobayashi K

更新日期：1995-12-01 00:00:00

abstract：:Salmonella serovars are associated with human diseases that range from mild gastroenteritis to host-disseminated enteric fever. Human infections by Salmonella enterica serovar Typhi can lead to typhoid fever, but this serovar does not typically cause disease in mice or other animals. In contrast, S. enterica serovar T...

journal_title：Infection and immunity

authors： Schwan WR,Huang XZ,Hu L,Kopecko DJ

更新日期：2000-03-01 00:00:00

abstract：:Nonvertebrate model hosts represent valuable tools for the study of host-pathogen interactions because they facilitate the identification of bacterial virulence factors and allow the discovery of novel components involved in host innate immune responses. In this report, we determined that the greater wax moth caterpil...

journal_title：Infection and immunity

authors： Miyata S,Casey M,Frank DW,Ausubel FM,Drenkard E

更新日期：2003-05-01 00:00:00

abstract：:Results from studies using mice deficient in specific complement factors and clinical data on patients with an inherited deficiency of the classical complement pathway component C2 suggest that the classical pathway is vital for immunity to Streptococcus pneumoniae. However, the consequences of defects in classical pa...

journal_title：Infection and immunity

authors： Yuste J,Sen A,Truedsson L,Jönsson G,Tay LS,Hyams C,Baxendale HE,Goldblatt F,Botto M,Brown JS

更新日期：2008-08-01 00:00:00

abstract：:Group B streptococci (GBS) adhere to surface receptors present on epithelial cells; these receptors include fibronectin and laminin. To identify other possible receptors, plasma membranes from A549 cells, a respiratory tract epithelial cell line, were prepared. These plasma membranes were tested in a protein blot anal...

journal_title：Infection and immunity

authors： Tamura GS,Nittayajarn A

更新日期：2000-04-01 00:00:00

abstract：:Persistent infection with Borrelia burgdorferi in the presence of a vigorous host immune response has been demonstrated in humans and in animal models of Lyme disease. Long-term persistence of B. burgdorferi was documented recently in our studies of BALB/c and C3H mice infected with cloned and uncloned strains of B. b...

journal_title：Infection and immunity

authors： Persing DH,Mathiesen D,Podzorski D,Barthold SW

更新日期：1994-08-01 00:00:00

abstract：:Although Streptococcus intermedius and Streptococcus mutans are regarded as members of the commensal microflora of the body, S. intermedius is often associated with deep-seated purulent infections, whereas S. mutans is frequently associated with dental caries. In this study, we investigated the roles of the S. mutans ...

journal_title：Infection and immunity

authors： Petersen FC,Assev S,van der Mei HC,Busscher HJ,Scheie AA

更新日期：2002-01-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4), which recognizes lipopolysaccharide from Gram-negative bacteria, plays a major role in resistance of mice and humans to Salmonella infection. In chickens, Salmonella may establish a carrier state whereby bacteria are able to persist in the host organism without triggering clinical signs. B...

journal_title：Infection and immunity

authors： Chaussé AM,Grépinet O,Bottreau E,Le Vern Y,Menanteau P,Trotereau J,Robert V,Wu Z,Kerboeuf D,Beaumont C,Velge P

更新日期：2011-08-01 00:00:00

abstract：:Humans are the sole reservoir of Neisseria gonorrhoeae, an organism which undergoes a marked increase in metabolic rate after exposure to a low-molecular-weight, heat-stable component(s) of human serum. Further studies on the effect of serum on gonococcal metabolism were undertaken. Gonococcal broth (GCB) is commonly ...

journal_title：Infection and immunity

authors： Britigan BE,Chai Y,Cohen MS

更新日期：1985-12-01 00:00:00

abstract：:Pneumolysin (PLY), an important virulence factor of Streptococcus pneumoniae, is known to exert various effects on the host immune cells, including cytokine induction, in addition to its known cytolytic activity as a member of the thiol-activated cytolysins. It is of interest to determine whether cytolytic activity is...

journal_title：Infection and immunity

authors： Baba H,Kawamura I,Kohda C,Nomura T,Ito Y,Kimoto T,Watanabe I,Ichiyama S,Mitsuyama M

更新日期：2002-01-01 00:00:00

abstract：:The Yersinia high-pathogenicity island (HPI) is common to multiple virulence strategies used by Escherichia coli strains associated with urinary tract infection (UTI). Among the genes in this island are ybtP and ybtQ, encoding distinctive ATP binding cassette (ABC) proteins associated with iron(III)-yersiniabactin imp...

journal_title：Infection and immunity

authors： Koh EI,Hung CS,Henderson JP

更新日期：2016-04-22 00:00:00

abstract：:Nasopharyngeal colonization represents the initial interaction between Haemophilus influenzae and its human host. Factors that influence bacterial carriage likely affect transmission and incidence of infection. Therefore, we investigated host factors involved in limiting H. influenzae colonization in BALB/c mice, as c...

journal_title：Infection and immunity

authors： Zola TA,Lysenko ES,Weiser JN

更新日期：2009-08-01 00:00:00

abstract：:The protective efficacy of Mycobacterium bovis BCG can be markedly augmented by stable integration of Mycobacterium tuberculosis genomic region RD1. BCG complemented with RD1 (BCG::RD1) encodes nine additional proteins. Among them, 10-kDa culture filtrate protein (CFP-10) and ESAT-6 (6-kDa early secreted antigenic tar...

journal_title：Infection and immunity

authors： Demangel C,Brodin P,Cockle PJ,Brosch R,Majlessi L,Leclerc C,Cole ST

更新日期：2004-04-01 00:00:00

abstract：:Arthritis is a frequent and major complication of infection with Borrelia burgdorferi sensu stricto. The antigens responsible for the induction of arthritis are unknown. Here we provide direct evidence that a major surface protein, outer surface protein A (OspA), can induce arthritis. Hamsters were vaccinated with 30,...

journal_title：Infection and immunity

authors： Croke CL,Munson EL,Lovrich SD,Christopherson JA,Remington MC,England DM,Callister SM,Schell RF

更新日期：2000-02-01 00:00:00

abstract：:The quantity of membrane-bound and extracellular exotoxin A in four strains of Pseudomonas aeruginosa was investigated. In strain PA-103, which is the prototype strain used for toxin production, all of the toxin was released into the growth medium and little toxin remained with the cell envelope. In a virulent strain ...

journal_title：Infection and immunity

authors： Fernandes PB,Cundy KR

更新日期：1980-05-01 00:00:00

abstract：:Bacillus cereus causes exotoxin-mediated diarrheal food poisoning. Hemolysin BL (HBL) is a well-characterized B. cereus toxin composed of three components (B, L1, and L2) that together possess hemolytic, cytotoxic, dermonecrotic, and vascular permeability activities. Here, we show that HBL causes fluid accumulation in...

journal_title：Infection and immunity

authors： Beecher DJ,Schoeni JL,Wong AC

更新日期：1995-11-01 00:00:00

abstract：:Candida albicans biofilms are formed through three distinct developmental phases and are associated with high fluconazole (FLU) resistance. In the present study, we used a set of isogenic Candida strains lacking one or more of the drug efflux pumps Cdr1p, Cdr2p, and Mdr1p to determine their role in FLU resistance of b...

journal_title：Infection and immunity

authors： Mukherjee PK,Chandra J,Kuhn DM,Ghannoum MA

更新日期：2003-08-01 00:00:00

abstract：:Once in the cytoplasm of mammalian cells, Shigella flexneri expresses a motile phenotype caused by polar directional assembly of actin. This process depends on accumulation of IcsA (VirG), a 120-kDa protein with ATPase activity, at the pole of the bacterium opposite to that at which ongoing septation occurs. IcsA is a...

journal_title：Infection and immunity

authors： d'Hauteville H,Dufourcq Lagelouse R,Nato F,Sansonetti PJ

更新日期：1996-02-01 00:00:00

abstract：:In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phe...

journal_title：Infection and immunity

authors： Rivas-Santiago B,Serrano CJ,Enciso-Moreno JA

更新日期：2009-11-01 00:00:00

abstract：:The Bordetella pertussis BrkA protein protects against the bactericidal activity of complement and antibody; however, some individuals mount an immune response that overcomes this bacterial defense. To further characterize this process, the bactericidal activities of sera from 13 adults with different modes of exposur...

journal_title：Infection and immunity

authors： Weiss AA,Mobberley PS,Fernandez RC,Mink CM

更新日期：1999-03-01 00:00:00

abstract：:Legionella anisa and the amoeba Hartmannella vermiformis were isolated from an indoor fountain implicated as the infectious reservoir in an outbreak of Pontiac fever. We evaluated the ability of this strain of L. anisa to multiply in cultures of an amoeba (H. vermiformis), a ciliated protozoan (Tetrahymena pyriformis)...

journal_title：Infection and immunity

authors： Fields BS,Barbaree JM,Sanden GN,Morrill WE

更新日期：1990-09-01 00:00:00

abstract：:We undertook a morphological and immunochemical comparison of purified outer membrane antigens from oral and nonoral isolates of Bacteroides asaccharolyticus. Electron micrographs of thin sections of whole bacteria revealed a compact, electron-dense capsule external to the outer membrane of oral strains. A loose, web-...

journal_title：Infection and immunity

authors： Mansheim BJ,Coleman SE

更新日期：1980-02-01 00:00:00

abstract：:The fucose-mannose ligand (FML) complex of Leishmania donovani is a promising vaccine candidate against murine and canine visceral leishmaniasis, and its main component is a 36-kDa nucleoside hydrolase (NH36). In this study, we tested the immune response and protection induced by the purified FML, the recombinant NH36...

journal_title：Infection and immunity

authors： Aguilar-Be I,da Silva Zardo R,Paraguai de Souza E,Borja-Cabrera GP,Rosado-Vallado M,Mut-Martin M,García-Miss Mdel R,Palatnik de Sousa CB,Dumonteil E

更新日期：2005-02-01 00:00:00

abstract：:Haemophilus ducreyi is resistant to killing by normal serum antibody and complement. We discovered an H. ducreyi outer membrane protein required for expression of serum resistance and termed it DsrA (for "ducreyi serum resistance A"). The dsrA locus was cloned, sequenced, and mutagenized. An isogenic mutant (FX517) of...

journal_title：Infection and immunity

authors： Elkins C,Morrow KJ Jr,Olsen B

更新日期：2000-03-01 00:00:00

abstract：:Periodontitis is a disease of polymicrobial etiology characterized by inflammation, degradation of host tissue, and bone that irreversibly destroys the supporting apparatus of teeth. Porphyromonas gingivalis contains lipid A with structural heterogeneity that has been postulated to contribute to the initiation of dysb...

journal_title：Infection and immunity

authors： Zenobia C,Hasturk H,Nguyen D,Van Dyke TE,Kantarci A,Darveau RP

更新日期：2014-02-01 00:00:00