Natural antibody to conserved targets of Haemophilus influenzae limits colonization of the murine nasopharynx.

abstract：:Interactions between bacteria and salivary components are thought to be important in the establishment and ecology of the oral microflora. alpha-Amylase, the predominant salivary enzyme in humans, binds to Streptococcus gordonii, a primary colonizer of the tooth. Previous studies have implicated this interaction in ad...

journal_title：Infection and immunity

authors： Rogers JD,Palmer RJ Jr,Kolenbrander PE,Scannapieco FA

更新日期：2001-11-01 00:00:00

abstract：:In this report, we demonstrate that the variable antigens present on the surface of Plasmodium knowlesi-infected erythrocytes could not be found on the surface of merozoites. A number of technical problems had to be solved to make such a comparative study possible, including the purification of merozoites by affinity ...

journal_title：Infection and immunity

authors： Hommel M,David PH

更新日期：1981-07-01 00:00:00

abstract：:Pertussis toxin (PT), a virulence factor secreted by Bordetella pertussis, contributes to respiratory tract infection and disease caused by this pathogen. By comparing a wild-type (WT) B. pertussis strain to a mutant strain with an in-frame deletion of the ptx genes encoding PT (DeltaPT), we recently found that the la...

journal_title：Infection and immunity

authors： Carbonetti NH,Artamonova GV,Andreasen C,Dudley E,Mays RM,Worthington ZE

更新日期：2004-06-01 00:00:00

abstract：:gammaG-globulin from nonimmunized rabbits and from rabbits immunized with various bacteria reacted in the immunofluorescence technique with protein A-containing Staphylococcus aureus. Pepsin digestion of most immunoglobulin preparations eliminated the reaction, thus showing that the Fc fragment is involved and that th...

journal_title：Infection and immunity

authors： Forsgren A,Forsum U

更新日期：1970-10-01 00:00:00

abstract：:Actinlike material was obtained from disrupted Pseudomonas aeruginosa cells by a modification of the method of Hancock and Nikaido (J. Bacteriol. 136:381-390) for isolating outer membrane vesicles. Pelleted membranes were dissolved in Laemmli sample buffer and electrophoresed in parallel lanes with purified rabbit ske...

journal_title：Infection and immunity

authors： Berk RS,Moon M,Higbee R,Cramer C,Roher A,Weis M,Hazlett L

更新日期：1985-11-01 00:00:00

abstract：:Monolayer cultures of LLC-MK2 rhesus monkey kidney cells become persistently infected with simian virus 40 after infection at input multiplicities of 100, 10, or 1 plaque-forming unit per cell. After 3 weeks, all cells of the cultures infected at a multiplicity of 1 plaque-forming unit per cell produced the simian vir...

journal_title：Infection and immunity

authors： Norkin LC

更新日期：1977-12-01 00:00:00

abstract：:Streptococcus pneumoniae cell wall and pneumolysin are important contributors to pneumococcal pathogenicity in some animal models. To further explore these factors in middle ear inflammation caused by pneumococci, penicillin-induced inflammatory acceleration was studied by using three closely related pneumococcal stra...

journal_title：Infection and immunity

authors： Sato K,Quartey MK,Liebeler CL,Le CT,Giebink GS

更新日期：1996-04-01 00:00:00

abstract：:The reproducibility of an experimental result is a fundamental assumption in science. Yet, results that are merely confirmatory of previous findings are given low priority and can be difficult to publish. Furthermore, the complex and chaotic nature of biological systems imposes limitations on the replicability of scie...

journal_title：Infection and immunity

authors： Casadevall A,Fang FC

更新日期：2010-12-01 00:00:00

abstract：:Vaccine candidates against Shigella dysenteriae type 1, which is associated with the most severe cases of bacillary dysentery, were constructed. The rfp and rfb gene clusters, which code for S. dysenteriae 1 O antigen biosynthesis, were randomly integrated into either the chromosome or the virulence plasmid of the rou...

journal_title：Infection and immunity

authors： Klee SR,Tzschaschel BD,Fält I,Kärnell A,Lindberg AA,Timmis KN,Guzmán CA

更新日期：1997-06-01 00:00:00

abstract：:Antibody to Pseudomonas aeruginosa exotoxin was detected in human sera by using a cytotoxicity-neutralization assay. Serum antitoxin was present in high titer in all 14 patients who recovered from serious pseudomonas infections (log2 of 50% neutralization titer, mean +/- standard deviation = 6.0 +/- 1.2). In contrast,...

journal_title：Infection and immunity

authors： Pollack M,Callahan LT 3rd,Taylor NS

更新日期：1976-10-01 00:00:00

abstract：:Chlamydia trachomatis is a strict human pathogen producing infections that cause medically important chronic inflammatory diseases, such as blinding trachoma and tubal factor infertility. Isolates exist as serotypes that fall into distinct biologic and pathological groups corresponding to differences in infection tiss...

journal_title：Infection and immunity

authors： Carlson JH,Hughes S,Hogan D,Cieplak G,Sturdevant DE,McClarty G,Caldwell HD,Belland RJ

更新日期：2004-12-01 00:00:00

abstract：:Inactivated Marek's disease virus-infected chicken kidney cells and inactivated MSB-1 lymphoblastoid Marek's disease tumor cells were used to immunize chickens as virus- and tumor-associated antigens, respectively. Immune and nonimmune birds were then challenged by exposure to live virulent Marek's disease virus. Both...

journal_title：Infection and immunity

authors： Murthy KK,Calnek BW

更新日期：1979-11-01 00:00:00

abstract：:Endotoxemia in rats is associated with the accumulation of neutrophils (polymorphonuclear leukocytes) within the airspaces of the lung. Polymorphonuclear leukocyte influx appears to be regulated by the intrapulmonary accumulation of chemotactic activity. Since alveolar macrophages (AMS) are prevalent cells in the airs...

journal_title：Infection and immunity

authors： Christman JW,Petras SF,Vacek PM,Davis GS

更新日期：1989-03-01 00:00:00

abstract：:Ocular toxoplasmosis is a potentially blinding intraocular inflammation. The intent of this study was to investigate the role of Fas-FasL interaction in a murine model of acquired ocular toxoplasmosis induced by intracameral inoculation of Toxoplasma gondii. Intraocular inflammation, Fas and FasL expression on lymphoc...

journal_title：Infection and immunity

authors： Hu MS,Schwartzman JD,Yeaman GR,Collins J,Seguin R,Khan IA,Kasper LH

更新日期：1999-02-01 00:00:00

abstract：:The parameters of a persistent-state measles virus infection in BGM/MV cells were examined. The BGM/MV cell line was established by cocultivation of measles virus-infected primary C3H mouse brain cells with a stable line of African green monkey kidney cells (BGM). Initially, a morphologically mixed population of cells...

journal_title：Infection and immunity

authors： Menna JH,Collins AR,Flanagan TD

更新日期：1975-01-01 00:00:00

abstract：:The contribution of murine Toll-like receptors 2 and 4 (TLR2 and -4, respectively) to cytokine induction by heat-killed bacteria was analyzed in vitro and in vivo. Gram-negative bacteria induced cytokines primarily via TLR4; the contribution of TLR2 was only minor. Neither TLR4 nor, surprisingly, TLR2 was required in ...

journal_title：Infection and immunity

authors： Lembo A,Kalis C,Kirschning CJ,Mitolo V,Jirillo E,Wagner H,Galanos C,Freudenberg MA

更新日期：2003-10-01 00:00:00

abstract：:Spleen cell cultures from guinea pigs given legionella pneumophila vaccine in complete Freund adjuvant or as a sublethal infection were inhibited in their migration activity in vitro when incubated with specific antigen. Both direct and indirect migration inhibition assays revealed sensitization of the guinea pigs to ...

journal_title：Infection and immunity

authors： Friedman H,Widen R,Lee I,Klein T

更新日期：1983-09-01 00:00:00

abstract：:l-Arginine (1 M) eluted measles virus adsorbed on monkey erythrocytes without affecting the infectious and hemagglutinating activities of the virus. This phenomenon was also observed for encephalomyocarditis virus and Newcastle disease virus. ...

journal_title：Infection and immunity

authors： Lebon P,Protat A,Moline P

更新日期：1975-06-01 00:00:00

abstract：:Toxin preparations were obtained by growing Clostridium difficile VPI strain 10463 in 2-liter brain heart infusion dialysis flasks at 37 degrees C for 3 days. The initial step of the purification scheme involved ultrafiltration through an XM-100 membrane filter. Two toxic activities, designated toxins A and B, were se...

journal_title：Infection and immunity

authors： Sullivan NM,Pellett S,Wilkins TD

更新日期：1982-03-01 00:00:00

abstract：:Plaque samples were obtained from tooth surfaces exhibiting typical lesions of root surface caries and were immediately cultured by a continuous anaerobic procedure. The bacterial composition of root caries flora was determined on individual samples. Representative isolates from each specimen were characterized by mor...

journal_title：Infection and immunity

authors： Syed SA,Loesche WJ,Pape HL Jr,grenier E

更新日期：1975-04-01 00:00:00

abstract：:In the present study, the role of virulence factors in and the effect of opsonization on the interactions between Bordetella pertussis and human monocytes were investigated. The methods used facilitated the distinction between attachment and ingestion of bacteria by monocytes. Nonopsonized virulent B. pertussis cells ...

journal_title：Infection and immunity

authors： Hazenbos WL,van den Berg BM,van't Wout JW,Mooi FR,van Furth R

更新日期：1994-11-01 00:00:00

abstract：:Vitamin D is an important regulator of the expression of antimicrobial peptides, and vitamin D deficiency is associated with respiratory infections. Regulating expression of antimicrobial peptides, such as the human cathelicidin antimicrobial peptide 18 (hCAP18)/LL-37, by vitamin D in bronchial epithelial cells requir...

journal_title：Infection and immunity

authors： Schrumpf JA,van Sterkenburg MA,Verhoosel RM,Zuyderduyn S,Hiemstra PS

更新日期：2012-12-01 00:00:00

abstract：:Fab fragments prepared from the immunoglobulin G monoclonal antibody (MAb) 4C12, which reacts with a determinant expressed on the hyphal extension of germ tubes of Candida albicans, inhibited germ tube formation, but intact MAb 4C12 did not. Indirect immunofluorescence showed a punctate binding pattern on cells incuba...

journal_title：Infection and immunity

authors： Casanova M,Martínez JP,Chaffin WL

更新日期：1990-11-01 00:00:00

abstract：:The ability to bind and utilize hemin is a trait common to many human pathogens. Nevertheless, the relationship between Legionella pneumophila, the agent of Legionnaires' disease, and hemin has received little attention. Thus, we explored the capacity of a virulent, serogroup 1 strain of L. pneumophila to bind hemin a...

journal_title：Infection and immunity

authors： O'Connell WA,Hickey EK,Cianciotto NP

更新日期：1996-03-01 00:00:00

abstract：:In this study, cytokine patterns produced by CD4(+) T cells isolated from antrum or corpus gastral biopsy specimens of 10 patients with Helicobacter pylori-positive gastritis were compared. To this end, expression of intracellular cytokines (interleukin-4 [IL-4] and gamma interferon) and of CD4 was assessed by flow cy...

journal_title：Infection and immunity

authors： Sommer F,Faller G,Konturek P,Kirchner T,Hahn EG,Zeus J,Röllinghoff M,Lohoff M

更新日期：1998-11-01 00:00:00

abstract：:Suppression of the host defense is one of the hallmarks of Yersinia enterocolitica infection. This enteric pathogen resists phagocytosis and interferes with macrophage functions from an extracellular localization (oxidative-burst generation and tumor necrosis factor alpha production). In this study, we investigated th...

journal_title：Infection and immunity

authors： Ruckdeschel K,Roggenkamp A,Lafont V,Mangeat P,Heesemann J,Rouot B

更新日期：1997-11-01 00:00:00

abstract：:Strains of type III group B streptococci isolated from patients with neonatal sepsis are generally resistant to complement-mediated phagocytic killing in the absence of specific antibody. It has been suggested that the resistance of type III group B streptococci to phagocytosis results from inhibition of alternative-c...

journal_title：Infection and immunity

authors： Marques MB,Kasper DL,Pangburn MK,Wessels MR

更新日期：1992-10-01 00:00:00

abstract：:Many pathogenic Escherichia coli produce the toxin alpha-hemolysin (Hly), and lipopolysaccharide (LPS), interleukin-1 (IL-1), and tumor necrosis factor (TNF) have all been recognized as important effector molecules during infections by gram-negative organisms. Despite the characterization of many in vitro effects of h...

journal_title：Infection and immunity

authors： Gleason TG,Houlgrave CW,May AK,Crabtree TD,Sawyer RG,Denham W,Norman JG,Pruett TL

更新日期：1998-09-01 00:00:00

abstract：:Interaction of bacteria with mucosal surfaces can modulate the production of proinflammatory cytokines and adhesion molecules produced by epithelial cells. Previously, we showed that expression of interleukin-8 (IL-8) and intercellular adhesion molecule 1 (ICAM-1) by gingival epithelial cells increases following inter...

journal_title：Infection and immunity

authors： Huang GT,Kim D,Lee JK,Kuramitsu HK,Haake SK

更新日期：2001-03-01 00:00:00

abstract：:The adherence of several strains of Escherichia coli to human buccal epithelial cells was studied, using cells obtained from five groups: healthy adults, healthy children, children with acute diarrhea, children with persistent diarrhea associated with cryptosporidial parasites, and children with noncryptosporidial per...

journal_title：Infection and immunity

authors： Walser BL,Newman RD,Lima AA,Guerrant RL

更新日期：1992-11-01 00:00:00